Download or read book Orthopaedic Implants Recommendations for Retrieval and Examination of Implants and Associated Tissues written by British Standards Institute Staff and published by . This book was released on 1990-08-31 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: Orthopaedic equipment, Implants (surgical), Surgery, Orthopaedics, Histology, Medical specimens, Sampling methods, Materials handling, Packaging, Transportation, Safety measures, Visual inspection (testing), Sterilization (hygiene), Medical equipment, Records (documents), Samples, Marking, Medical inspection, Biological analysis and testing
Download or read book Retrieval and Analysis of Orthopaedic Implants written by Allan Weinstein and published by . This book was released on 1977 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Implant Retrieval written by United States. National Bureau of Standards and published by . This book was released on 1981 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Retrieval Analysis and Finite Element Modeling of Orthopaedic Porous Coated Implants written by Josa Ann Hanzlik and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Nationwide Inpatient Sample (NIS) studies have shown that implant loosening remains one of the common reasons for revision in total joint replacement. In an effort to reduce loosening caused by long-term breakdown of the cement mantle, manufacturers introduced cementless technologies to provide biological fixation by hard tissue ingrowth at the bone-implant interface. One new material, porous tantalum, has had promising clinical results with well-fixed implants and relatively few reported cases of loosening. The factors that may be causing the lower incidence of aseptic loosening remain unknown. Therefore, the goal of this dissertation was to investigate the factors affecting bone fixation in porous tantalum implants through retrieval analysis and finite element (FE) modeling. Through the Implant Research Center0́9s retrieval program, the proportion of implants revised for aseptic loosening was compared between the porous tantalum implants and historical porous-coated implants. Retrieval analysis protocols were developed to assess and determine factors that affect bone ingrowth in porous tantalum hip and knee implants. Porous tantalum tibial trays were histologically analyzed to determine locations of fibrous tissue or bone ingrowth. The results showed that the amount of bone observed varied by implant type and location within each implant for retrieved porous tantalum acetabular shells, femoral stems, patellas and tibial trays. Retrieval results showed that modular tibial tray implants had higher bone ingrowth than the monoblock tibial trays. However, the bone ingrowth in the porous tantalum was lower than that observed in historical porous-coated implants. Histological analyses of tibial trays demonstrated bone ingrowth primarily in the superficial depth of the tibial trays, with fibrous tissue also present. The FE models showed that there was more favorable initial implant stability in the modular tibial tray compared to the monoblock implant. This study showed that the lower incidence of aseptic loosening did not appear to be associated with increased bone ingrowth for the retrieved porous tantalum hip and knee implants. Initial FE models showed that lower micromotion for the modular tibial tray compared the monoblock. This dissertation presents a multifaceted approach for analysis of highly porous biomaterials.
Download or read book Handbook Of Biomaterials Evaluation written by Andreas F von Recum and published by CRC Press. This book was released on 1998-12-18 with total page 944 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook addresses the needs of those who are involved in inventing, developing, and testing implants and are concerned about the interactions between biomaterial and body tissue. The authors explore the physical, chemical, mechanical and regulatory considerations of synthetic materials used in surgical and implant procedures, and how these factors impact the latest developments and new approaches. This updated edition provides the biomaterials professional with necessary information on a range of issues, including bulk characterization, surface evaluations, toxicological evaluations, in vitro methods for safety evaluation, methods for evaluating materials in special applications, surgical considerations, systems implantology, soft and hard tissue history, regulatory aspects, and clinical trials.
Download or read book Histological Diagnosis of Implant associated Pathologies written by Veit Krenn and published by Springer. This book was released on 2017-05-09 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt: Histological evaluation of the periprosthetic soft and osseous tissues is an important analytical tool. Its standardization is essential to generate accurate and reproducible data which allow comparisons for academic institutions, arthroplasty registries, and government regulatory agencies worldwide. It is also part of multidisciplinary evaluation of orthopedic implant failures and provides valuable information to be integrated with the clinical data, allergological tests, radiological exams, microbiological analysis, and biomechanical assessment of the implant wear.
Download or read book Analysis of Comprehensive Measurements from Retrieved Implants to Determine Factors Contributing to Failure Modes and Wear written by Harry McKellop and published by . This book was released on 2013 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implant retrieval analysis offers the opportunity to investigate the causes for failure and mechanisms of wear occurring in vivo, and the biological responses to the wear debris generated during those wear processes. Although the ASTM standard F561 ["Standard for the Retrieval and Analysis of Medical Devices, and Associated Tissues and Fluids,"Annual Book of ASTM Standards, ASTM International, West Conshohocken, PA] recommends a multifaceted analysis (tissue histopathology, chemical analysis for trace metal content, wear particle isolation and characterization, and component analysis) that proceeds from least destructive methods such as visual inspection to destructive means, such as metallographic analysis, typically, only one of these aspects is the focus of published studies of failed metal-on-metal implants. This paper reiterates the advantages of a comprehensive, multifaceted retrieval approach, involving the examination of the radiographic and clinical data, the measurement of wear and characterization of damage via CMM, SEM, semi-quantitative histological analysis of tissue, and the morphological and chemical characterization of wear debris from associated tissues and fluids. The results of these analyses are then correlated with clinical, implant, and surgical factors to establish relationships and risk factors for wear and failure.
Download or read book Retrieval and Analysis of Orthopaedic Implants written by Allan Weinstein and published by Forgotten Books. This book was released on 2018-01-12 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Excerpt from Retrieval and Analysis of Orthopaedic Implants: Proceedings of a Symposium Held at the National Bureau of Standards, Gaithersburg, Maryland, March 5, 1976 Welcome to the National Bureau of Standards (nbs) and to the symposium on Retrieval and Analysis of Orthopaedic Implants. We at nbs are pleased to cosponsor this symposium with the Food and Drug Administration, the American Society for Testing and Materials, the American Academy of Orthopaedic Surgeons, the Orthopaedic Surgical Manufacturers Association, and the Society for Biomaterials. The list of organizations is long and impressive, to be sure. I believe, however, that this multiple sponsorship attests to both the importance of the subject and the fact that a wide variety of competences and interests must be brought to gether if we are to reach our common goal of improving the performance of orthopedic implants, I personally am pleased to appear before you to launch this symposium aimed at achieving this goal. I have felt for many years that nbs could make unique contributions by helping to provide standards, test methods, and data that would enable manufacturers, surgeons, and agencies of Government to operate from common bases. My deputy, Dr. Emanuel Horowitz, and I have sought to build a program to meet the needs of the user community. Dr. Horowitz has been directly involved in many aspects of orthopedic implant development and has worked toward accelerating the development of much needed standards. Our conviction that nbs could make a unique contribution in this area is based upon a number of factors: our long tradi tion for work in failure analysis; our long association with the American Dental Association; and our multidisciplinary laboratory built around competences in chemistry and physics and focused on the properties of metals, ceramics, and polymers. Though we believe that our competence base could be effectively utilized in improving the performance of implant materials, we are very mindful of the fact that standards and measurements are only a part of the problem. For this reason we have sought from the very first to operate through such groups and agencies as those represented here today. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
Download or read book Retrieval and Analysis of Orthopaedic Implants written by Emanuel Horowitz and published by . This book was released on 1977 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book NBS Special Publication written by and published by . This book was released on 1968 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Aseptic Loosening of Orthopedic Implants written by Mehdi Amirhosseini and published by Linköping University Electronic Press. This book was released on 2019-05-24 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aseptic loosening is the main cause of failure of orthopedic prostheses. With no pharmaceuticals to prevent or mitigate periprosthetic bone degradation, a surgery to replace the loose implant with a new one is the only choice to restore patients’ function. Most studies on mechanisms for aseptic loosening investigate wear debris particle-induced osteolysis. However, pathological loading conditions around unstable implants can also trigger osteoclast differentiation and bone loss. In the first study, global gene expression changes induced by mechanical instability of implants, and by titanium particles were compared in a validated rat model for aseptic loosening. Microarray analysis showed that similar signaling pathways and gene expression patterns are involved in particle- and instability-induced periprosthetic osteolysis with an early onset innate immune response as a hallmark of osteolysis induced by mechanical instability. Further, effects of potential therapeutics on restriction of excessive osteoclast differentiation were evaluated. Wnt signaling pathway is known to regulate bone remodeling. In the second study, effects of inactivation of glycogen synthase kinase 3 beta (GSK-3?), a negative regulator of canonical Wnt signaling, on instability-induced periprosthetic osteolysis were examined using our rat model for aseptic loosening. Inhibition of GSK-3? led to a decrease in osteoclast numbers in the periprosthetic bone tissue exposed to mechanical instability while osteoblast perimeter showed an increase. This was accompanied by higher bone volume fraction (BV/TV) in animals treated with the GSK-3? inhibitor. In the third study, potential beneficial effects of two selective inhibitors of cyclindependent kinase 8/19 (CDK8/19) on bone tissue were evaluated. CDK8/19 is a Mediator complex-associated transcriptional regulator involved in several signaling pathways. CDK8/19 inhibitors, mainly under investigation as treatments for tumors, are reported to enhance osteoblast differentiation and bone formation. We show in this study, for the first time, that inhibition of CDK8/19 led to marked suppression of osteoclast differentiation from bone marrow macrophages in vitro through disruption of the RANK signaling. In mouse primary osteoblasts downregulation of osteopontin mRNA, a negative regulator of mineralization, together with increased alkaline phosphatase activity and calcium deposition indicated that osteoblast mineralization was promoted by CDK8/19 inhibition. Moreover, local administration of a CDK8/19 inhibitor promoted cancellous bone regeneration in a rat model for bone healing. These studies contribute to better understanding of mechanisms behind mechanical instability-induced periprosthetic osteolysis and propose potential therapeutics to restrict bone loss with effects on both osteoclasts and osteoblasts.
Download or read book Retrieval and Analysis of Orthopaedic Implants Proceedings of a Symposium National Bureau of Standards Gaithersburg Md 1976 written by A. Weinstein and published by . This book was released on 1977 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bulletin of Prosthetics Research written by and published by . This book was released on 1980 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Retrieval and Analysis of Orthopaedic Implants written by Emanuel Horowitz and published by . This book was released on 1977 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomaterials Science written by Buddy D. Ratner and published by Academic Press. This book was released on 2012-12-31 with total page 1610 pages. Available in PDF, EPUB and Kindle. Book excerpt: The revised edition of this renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science. It provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. - Over 29,000 copies sold, this is the most comprehensive coverage of principles and applications of all classes of biomaterials: "the only such text that currently covers this area comprehensively" - Materials Today - Edited by four of the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials - Fully revised and expanded, key new topics include of tissue engineering, drug delivery systems, and new clinical applications, with new teaching and learning material throughout, case studies and a downloadable image bank
Download or read book Fundamentals of Implant Dentistry written by Gerard Byrne and published by John Wiley & Sons. This book was released on 2014-03-21 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Implant Dentistry is a basic guide to foundational knowledge and skills and their application in clinical practice. More comprehensive than a procedural atlas and more accessible than a specialist reference, this text is an indispensable tool for dental students and clinicians beginning work with dental implants. Fundamentals of Implant Dentistry provides a concise yet comprehensive look at the basic background and science of implantology and includes practical, evidence‐based instruction on common procedures such as single implant crowns, bridges and overdentures. Well‐illustrated with clear line drawings and clinical photos, the book serves as the perfect introduction to this exciting area of dentistry.
Download or read book Spine Surgery 2 Vol Set E Book written by Edward C. Benzel and published by Elsevier Health Sciences. This book was released on 2012-05-14 with total page 2912 pages. Available in PDF, EPUB and Kindle. Book excerpt: Build a solid foundation of knowledge based on the fundamentals and employ step-by-step instruction from Spine Surgery. Edited by Edward C. Benzel, this best-selling medical reference explores the full spectrum of surgical techniques used in spine surgery and delivers the comprehensive, cutting-edge guidance you need to achieve successful outcomes. Online access, thorough updates, contributions by leading international authorities, an abundance of detailed illustrations, and procedural video clips provide everything you need to avoid and manage complex problems. Glean essential, up-to-date, need-to-know information in one comprehensive reference that explores the full spectrum of surgical techniques used in spine surgery. Hone your surgical skills and technique with intraoperative videos and more than 800 outstanding illustrations demonstrating each technique step by step. Grasp and apply the latest knowledge from more than 25 brand-new chapters, as well as extensive revisions or total rewrites to the majority of existing chapters to present all of the most up-to-date information available on every aspect of spine surgery including motion preservation technologies, endovascular management, back pain and psychosocial interactions, biomechanics, and more. Consult with the best. Renowned neurosurgery authority Edward C. Benzel leads an international team of accomplished neurosurgeons and orthopedic surgeons - many new to this edition - who provide dependable guidance and share innovative approaches to surgical techniques and complications management. Equip yourself to address increasing occurrences of pain among aging and physically active patients. Access the information you need, where you need it on your laptop or mobile device via expertconsult.com, with fully searchable text, a wealth of procedural videos, online updates from the experts, downloadable image gallery and links to PubMed.
