Download or read book Toxic Phosphorus Esters written by Richard D. O'Brien and published by Elsevier. This book was released on 2013-10-22 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxic Phosphorus Esters: Chemistry, Metabolism, and Biological Effects aims to become a source book on organophosphate research and show how the understanding of the events following organophosphate poisoning of animals can be understood in terms of events at the molecular level. The manuscript first offers information on nonenzymic reactions and the reaction with cholinesterase in vitro. Discussions focus on hydrolysis, isomerization, oxidation, phosphorylation of the enzyme, and selectivity for different cholinesterases. The text then examines enzymic degradation and activation in vitro, effects in mammals, and effects on isolated whole tissues. The publication ponders on the effects in insects and plants, including results of poisoning, metabolism, resistance, antagonism and synergism, and phytotoxicity. The text also reviews selective toxicity, as well as excretion and storage, metabolism, design of new selective compounds, and nature of the target. The manuscript is a dependable reference for readers interested in the composition, reactions, and effects of toxic phosphorus esters.
Download or read book Organophosphorus Esters written by David Ray and published by Mrc Institute for Environment and Health. This book was released on 1998 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Organophosphates Chemistry Fate and Effects written by Janice E. Chambers and published by Elsevier. This book was released on 2013-10-22 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts review the reactivity of organophosphorus compounds with cholinesterase, as well as their metabolism and biological effects on humans and other nontarget organisms. The book not only covers the anticholinesterase actions of organophosphates, but also other, presumably independent, effects, such as teratogenicity, delayed neuropathy, immunotoxicity, and behavioral toxicity. - Offers crucial overviews of chemical and biochemical reactivity and biological responsiveness of mainly nontarget organisms - Reviews new developments in assessment of metabolism and disposition of organophosphorus compounds - Examines organophosphorus compound-induced toxicity mediated by mechanisms other than inhibition of acetylcholinesterase - Covers new research on differences in toxicity induced by the variety of organophosphorus - Analyzes current controversies on the relevance of certain biochemical parameters in actual organophosphate toxicity in vivo
Download or read book Organophosphorus Pesticides written by Morifusa Eto and published by CRC Press. This book was released on 2018-01-18 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to get a general concept of organophosphorus pesticides with such a variety in structure and biological activities, consideration of each aspect of chemistry, biochemistry, and the applied sciences is necessary. This book consists of these three main parts. After the presentation of the background of phosphorus chemistry in Chapter 1, stress was put on the chemical and biochemical reactions of organophosphorus pesticides, including synthesis, analysis, metabolism mode of action, and other interesting aspects in Chapter 2 to 4, and on the structure-pesticidal activity relationship in Chapter 5.
Download or read book Organic Compounds in Organophosporus Pesticide Manufacturing Wastewaters written by Mark Marcus and published by . This book was released on 1978 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Organophosphorus Chemistry written by Robert Engel and published by CRC Press. This book was released on 1992-06-19 with total page 916 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical work summarizes the development of organophosphorus chemistry in topical areas and details the discipline's current state - providing applications and experimental procedures throughout.;Written by 18 leading authorities in the field, the Handbook of Organophosphorus Chemistry: examines advances in the mechanistic understanding of the Perkow and related organophosphorus reactions; describes methods for the reduction of quinquevalent to trivalent phosphorus and their applications to standard synthetic procedures; emphasizes the preparation of phosphonates bearing hydroxy, amino, and thiol functions at the alpha-position relative to the phosphoryl group; reviews the basics of NMR as it applies to the 31P nucleus, considering the use of the latest measurement techniques in solving structural and mechanistic problems; compares the characteristics of polymer-based and monomeric materials; and presents recent progress in the design of insecticides and covers their chemical and biological characteristics.;Generously referenced with close to 3000 bibliographic citations, the Handbook of Organophosphorus Chemistry is an important volume for organic, medicinal, and agricultural chemists and biochemists; pharmacists; chemical engineers; and graduate-level students in these disciplines.
Download or read book The Chemistry of Organophosphorus Pesticides written by C. Fest and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid progress in the field of organophosphate compounds has made this new edition necessary. Particular attention has been paid to new developments in biologically active products as this is probably of greatest interest to practical chemists. I have therefore updated the chapter on chemistry and, in connection with this, rewritten the chapter on metabolism. I should especially like to thank Professor Dr. HELLMUT HOFFMANN for his constant encouragement and interest in my work and for many fruitful discus sions. The co-author to the 1st edition, Dr. KARL-JULIUS SCHMIDT, died suddenly on November 21, 1980. I treasure the memory of a valued colleague of many years standing. Elberfeld, January 1982 CHRISTA FEST VII Preface to the First Edition Our intention has been to provide a short introduction to the chemistry and mode of action of insecticidal phosphoric acid compounds, with particular ref erence to the relationship between structure and activity. The yearly produc tion of these pesticides is now approaching 100,000 tons and thus offers an im portant example of applied research. If, however, one examines the historical development of these compounds, it is apparent that this was preceded by a hundred years of pure chemistry of phosphorus.
Download or read book Recognition and Management of Pesticide Poisonings 5th Ed written by J. Routt Reigart and published by DIANE Publishing. This book was released on 2009-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 5th ed. is an update and expansion of the 1989 4th ed. This EPA manual provides health professionals with information on the health hazards of pesticides currently in use, and current consensus recommendations for management of poisonings and injuries caused by them. As with previous updates, this new ed. incorporates new pesticide products that are not necessarily widely known among health professionals. Contents: (1) General Information: Introduction; General Principles in the Management of Acute Pesticide Poisonings; Environmental and Occupational History; (2) Insecticides; (3) Herbicides; (4) Other Pesticides; (5) Index of Signs and Symptoms; Index of Pesticide Products. Charts and tables.
Download or read book Toxicology of Organophosphate and Carbamate Compounds written by Ramesh C Gupta and published by Academic Press. This book was released on 2011-04-28 with total page 781 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. - Describes everything you need to know about Organophosphates and Carbamates - Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants - Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates - Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases - Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity - Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis - Provides in vitro and in vivo models for neurotoxicity testing - Integrates knowledge of studies in lab animals and humans - Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues - Describes management of Anticholinesterase poisoning in humans
Download or read book Organophosphorus Monomers and Polymers written by Ye. L. Gefter and published by Elsevier. This book was released on 2013-09-03 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organophosphorus Monomers and Polymers is the first attempt at a generalization and systemization of existent knowledge of the methods of synthesis and the basic properties of monomers and polymers of organophosphorus compounds, and also of their fields of application. It contains valuable reference material, collated in tables (physical constants of the monomers, properties of the polymers and copolymers, etc.). The literature used by the author has covered journals, patents and books up to 1958, and in some cases more recent results are included. The monomers and polymers are tabulated according to the particular class of phosphorus-containing compounds to which they belong: acids of phosphorus, their derivatives, phosphines, polymers and co-polymers of unsaturated esters of acids of phosphorus, etc. Groups of monofunctional unsaturated phosphorus-containing compounds (acids, acid chlorides, amides, etc.) are listed in the order of: (a) the distance of the multiple bonds from the phosphorus atom, and (b) the number of multiple bonds. Within each group, the unsaturated substances are listed from simple to complex according to the rules laid down in The Chemist's Handbook. The book is intended for scientists, research workers, engineers, and technologists working on the preparation, manipulation, and investigation of monomers and high molecular weight compounds, and also for students studying related branches of chemistry.
Download or read book Metabolism of Organophosphorus Insecticides and Alkyl Phosphorus Esters by Soil Microorganisms written by James Michael Tiedje and published by . This book was released on 1966 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Enzyme Inhibitors as Substrates written by W. Norman Aldridge and published by North-Holland. This book was released on 1972 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dictionary of Organophosphorus Compounds written by R. Edmundson and published by CRC Press. This book was released on 1987-11-19 with total page 1404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Chemistry and Use of Organophosphorus Compounds written by and published by . This book was released on 1963 with total page 956 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Organophosphorus Compounds written by Gennady M. Kosolapoff and published by . This book was released on 1950 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemistry and Fate of Organophosphorus Compounds written by E. Merian and published by Taylor & Francis. This book was released on 1987 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1987. Routledge is an imprint of Taylor & Francis, an informa company.
Download or read book Organophosphorus Pesticides written by Morifusa Etō and published by . This book was released on 1974 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nomenclature. Phosphates. Phosphorothionates. Phosphorothilothionates. Phosphorothiolates. Derivates of phosphoramidic acid. Phosphonates. Hydrolysis. Chemical reactions. Biochemistry. Individual Pesticides.
