Download or read book Oral Tolerance written by Howard L. Weiner and published by . This book was released on 1996 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents papers and poster abstracts from the spring 1995 title conference held in New York City, detailing mechanisms of oral tolerance and immune regulation. Sections on anatomy and physiology; mechanisms of oral tolerance; modulation of oral tolerance; and human and animal models of oral toleranc
Download or read book Oral Tolerance written by Olivier Morteau and published by Springer Science & Business Media. This book was released on 2004-08-10 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral tolerance is a major immunological property of the gastrointestinal mucosa. It plays a critical role in immune defence by preventing inflammatory and allergic responses to dietary and non pathogenic microbial antigens. The interest in oral tolerance has been renewed in the recent years, due to novel insights on its cellular mechanisms and potential clinical applications in the treatment of autoimmune diseases. Oral Tolerance: Cellular and Molecular Basis, Clinical Aspects, and Therapeutic Potential, has been designed as a concise yet comprehensive overview of the newest fundamental and clinical advances in the field. Based on the outstanding contribution of world experts, this book will be helpful to students, clinicians, and researchers working in mucosal immunology and gastroenterology. The first part of this volume describes the structure and functions of the gastrointestinal mucosa and the fundamental features and mechanisms of oral tolerance, including the role of T cells, cytokines, IgA antibodies, and bacterial antigens. The second part explores the clinical implications of the disruption of oral tolerance in Inflammatory Bowel Diseases, food and milk allergies, and coeliac disease in particular. The final chapter focuses on the clinical potential of oral tolerance as a promising therapeutic tool.
Download or read book Oral Tolerance written by Howard L. Weiner and published by . This book was released on 2004 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brings three areas together to continue to promote the expansion of knowledge in the area; the explosion in understanding the potential mechanisms of oral tolerance through the use of mouse models, a greater appreciation for the existence of novel regulatory T cells, and a clearer view of the way in which the mucosal immune system responds.
Download or read book Mechanisms of Oral Tolerance written by Hae-Ock Lee and published by . This book was released on 1999 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral protein antigen administration induces a state of immunologic tolerance termed oral tolerance. In the first part of the dissertation, we characterized systemic immune tolerance in adoptive transfer recipient (ATR) mice. Adoptive transfer of TCR transgenic cells from DO11.10 mice provides a means for following antigen-specific T cell responses in vivo. In ATR mice, oral protein activated antigen-specific T cells in the gut associated lymphoid tissue (GALT) and periphery. T cell activation accompanied systemic reduction of IL-2 production and selective induction of IFN-gamma in GALT. Oral antigen induced the homing molecules alpha4beta7, alpha4beta1, and P-selectin ligands on Tg + T cells in Peyer's patches and mesenteric lymph nodes. That suggested tolerant T cells migrate outside GALT. Oral tolerance was demonstrated by reduced T cell responses to peptide antigen administration in adjuvant. OVA feeding blunted Tg+ T cell expansion. T cell effector functions (DTH and antibody responses) and cytokine productions (IFN-gamma, IL-4, and TGF-beta) were reduced. To test the importance of IFN-gamma induction by oral antigen, we blocked IFN-gamma by neutralizing antibodies or utilized IFN-gamma-deficient mice. The absence of IFN-gamma did not interfere with blunted T cell expansion, reduction in cytokines, or the tolerance in antibody responses. In contrast, IFN-gamma inhibition abrogated oral antigeninduced reductions in DTH responses. Furthermore, T cell accumulation at cutaneous sites of inflammation was markedly increased in anti-IFN-gamma mAb-treated mice. These observations suggest that the role of IFN-gamma in oral tolerance may be to limit T cell migration to the sites of effector immune responses.
Download or read book Janeway s Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Download or read book Mechanisms of Immune Regulation written by Richard D. Granstein and published by S. Karger AG (Switzerland). This book was released on 1994 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among the topics reviewed are T and B cell tolerance, clonal deletion, suppressor cells, mechanisms of immune privileged sites and experimental models of tumor immunity. Oral tolerance, ultraviolet radiation and photosensitized effects on immunity, allograft management, T cell vaccination and regulation of immunity with T cell epitopes are discussed from the point of view of possible therapeutic application.
Download or read book Oral Tolerance written by Olivier Morteau and published by Springer. This book was released on 2010-12-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral tolerance is a major immunological property of the gastrointestinal mucosa. It plays a critical role in immune defence by preventing inflammatory and allergic responses to dietary and non pathogenic microbial antigens. The interest in oral tolerance has been renewed in the recent years, due to novel insights on its cellular mechanisms and potential clinical applications in the treatment of autoimmune diseases. Oral Tolerance: Cellular and Molecular Basis, Clinical Aspects, and Therapeutic Potential, has been designed as a concise yet comprehensive overview of the newest fundamental and clinical advances in the field. Based on the outstanding contribution of world experts, this book will be helpful to students, clinicians, and researchers working in mucosal immunology and gastroenterology. The first part of this volume describes the structure and functions of the gastrointestinal mucosa and the fundamental features and mechanisms of oral tolerance, including the role of T cells, cytokines, IgA antibodies, and bacterial antigens. The second part explores the clinical implications of the disruption of oral tolerance in Inflammatory Bowel Diseases, food and milk allergies, and coeliac disease in particular. The final chapter focuses on the clinical potential of oral tolerance as a promising therapeutic tool.
Download or read book Oral Tolerance written by Dominique Bagnard, Ph.D. and published by . This book was released on 2006-12-01 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pediatric Food Allergy written by Ruchi S. Gupta and published by Springer Nature. This book was released on 2020-03-02 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive and practical, this book thoroughly addresses the full range of concerns related to food allergies in the pediatric patient. As food allergies in the pediatric population increase in number and severity, Pediatric Food Allergy: A Clinical Guide provides information on new guidelines and potential treatment options, as well as working to improve awareness, diagnosis, management and prevention practices. Written by experts in their respective fields, chapters are divided into five sections. Opening with an introduction and overview of particular concerns and issues specific to food allergy in the pediatric population, sections two and three address diagnosis and management of comorbid conditions in food allergy, along with development of food allergies and current prevention recommendations. Sections four and five cover food allergy management, prognosis, and therapeutic options with a look to future developments, while all sections include a discussion of epidemiology, differential diagnoses of other potential food-related diseases. In Pediatric Food Allergy: A Clinical Guide, pediatricians and allergists alike will find an invaluable resource as they work with this vulnerable patient population.
Download or read book Improvement of Oral Tolerance During Disease a Role for Neurotransmitters written by Pieter Maria Cobelens and published by . This book was released on 2002 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Caffeine for the Sustainment of Mental Task Performance written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-07 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.
Download or read book Essentials of Mucosal Immunology written by Martin F. Kagnoff and published by Academic Press. This book was released on 1996-08-01 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Mucosal Immunology presents basic concepts as well as new and exciting advances in mucosal immunology and inflammation, the development of mucosal vaccines, and the role of the immune system in mucosal disease. Specific chapters highlight novel approaches to the treatment of autoimmune disease, including the use of oral tolerance; approaches to and vectors for new vaccines; and current concepts in mucosal inflammation and its role in inflammatory bowel disease and ulcer disease. Contains the most current research on mucosal immunology and is comprehensive in scope Includes ideal coverage of both the basic and clinical aspects of the mucosal immune system Provides an understanding of the mucosal immune system with regard to new treatments and preventative methods, including vaccine development Includes contributions from an international team of experts
Download or read book Principles of Mucosal Immunology written by Phillip Smith and published by Garland Science. This book was released on 2020-04-21 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: This respected graduate-level textbook provides comprehensive and accessible coverage of the basic and clinical aspects of the mucosal immune system, addressing the major components of the mucosal barrier ̶ gastrointestinal, upper and lower respiratory, ocular, and genitourinary mucosal immune systems ̶ in a highly user-friendly style. The editors of and contributors to the book, all internationally-recognized leaders, present the current principles, concepts, and basic processes involved in mucosal immunology, mucosal diseases, and host defense at mucosal surfaces. Topics discussed include the development and structure of the mucosal immune system and its cellular constituents, host-microbe relationships, infection, mucosal diseases, and vaccines. The second edition has been carefully updated throughout to reflect the latest developments from clinical research and key literature has been fully updated.
Download or read book Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence written by World Health Organization. Department of Mental Health and Substance Abuse and published by World Health Organization. This book was released on 2009 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: "These guidelines were produced by the World Health Organization (WHO), Department of Mental Health and Substance Abuse, in collaboration with the United Nations Office on Drugs and Crime (UNODC) a Guidelines Development Group of technical experts, and in consultation with the International Narcotics Control Board (INCB) secretariat and other WHO departments. WHO also wishes to acknowledge the financial contribution of UNODC and the Joint United Nations Programme on HIV/AIDS (UNAIDS) to this project. " - p. iv
Download or read book Antigen specific Oral Tolerance for the Treatment of Inflammatory and Allergic Diseases written by Inge Louise Huibregtse and published by . This book was released on 2009 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Oral Mucositis written by Stephen T Sonis and published by Springer Science & Business Media. This book was released on 2013-11-12 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment tolerance is a challenge for most cancer patients, and it is therefore essential that healthcare professionals (HCP) are quick to recognize adverse events and implement management strategies to address them. This pocket book provides an in-depth guide to the epidemiology, diagnosis and management of oral mucositis, a common adverse event of chemotherapy.
Download or read book Handbook of Mucosal Immunology written by and published by Academic Press. This book was released on 2012-12-02 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers have recently made tremendous progress in the area of mucosal immunology, greatly increasing our understanding of the common mucosal immune system, mucosal infections, and oral immunization. However, thisresearch has not previously been made available in a single work. In its large 81/2"x 11"format, Handbook of Mucosal Immunology covers the entire spectrum of mucosal immunity and is organized in two main sections to present the basic biology of the common mucosal immune system and the immune responses of the mucosae.The first section provides an introduction and historical perspective of the mucosal immune system and includes comprehensive discussion of the development and physiology of mucosal defense. It discusses such topics as the structure and function of themucosal epithelium, characteristics of mucosal-associated lymphoid tissue (MALT), Peyers patches, and concepts of mucosal vaccines. The second section focuses on the secretory immune system with special reference to mucosal diseases in the digestive (GALT), respiratory (BALT), and genitourinary tracts. This information is especially important in light of the current interest in the mechanisms, transmission, and prevention of infectious diseases such as AIDS, hepatitis, and tuberculosis.Virtually all chapters have been authored by the original investigators responsible for key observations on which current concepts are based. This handbook will be an invaluable resource for a diverse group of both researchers and practicing clinicians.Molecular biologists, immunologists, veterinarians, public health workers, physicians in specialties from pediatrics to pulmonology, and graduate students of mucosal immunology will all find this handbook the most complete work on the subject.
