Download or read book Optogenetics A Roadmap written by Albrecht Stroh and published by . This book was released on 2018 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the optogenetics workflow, and covers topics on viral vectors, targeting strategies, choice on opsins, animal models and readouts, and applications in systems neuroscience. This book shows readers how to identify the critical aspects of each methodological step, and how to determine the necessary level of complexity to address the particular research question. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and cutting-edge, Optogenetics: A Roadmap is a valuable guide for both the optogenetics novices and the experts.
Download or read book Optogenetics written by Peter Hegemann and published by Walter de Gruyter. This book was released on 2013-08-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optogenetics combines genetic engineering with optics to observe and control the function of cells using light, with clinical implications for restoration of vision and treatment of neurological diseases. As a new discipline much of the basic science and methods are currently under investigation and active development, thus there is a strong need for introductory literature in this field. This graduate level textbook provides an overview of the field of optogenetics in 5 concise chapters: Optogenetic tools, Applications in cellular systems, Mapping neuronal networks, Clinical applications and Restoration of vision and hearing. The concept and content was developed with top international researchers and students at a prestigious Dahlem Conference workshop.
Download or read book Opsin free Optogenetics written by Yubin Zhou and published by CRC Press. This book was released on 2022-12-14 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optogenetics represents a breakthrough technology capable of dynamically modulating molecular and cellular activity in live cells with high precision. This transformative technology made it possible to reversibly interrogate protein actions, cellular events, and animal behaviors with a simple flash of light. Manipulating the temporal and spatial profile of light enabled precise control of membrane potentials. This feature has inspired non-opsin-based optogenetics, which not only inherits the precise spatiotemporal resolution but also expands the targets into a diverse pool of biomolecules such as membrane receptors, ion channels, kinases, GTPases, and transcription factors. This book is unique because it emphasizes the design and applications of opsin-free optogenetic tools. Key Features Describes new developments in non-opsin-based optogenetic tools Introduces cutting-edge methods for precise modulation of cell signaling Highlights applications of optogenetic regulation of cellular functions Covers contributions from an international team of leading experts Related Titles Lim, W. & B. Mayer – Cell Signaling (ISBN 9780815342441) Ayyanathan, K., ed. – Cancer Cell Signaling: Targeting Signaling Pathways Toward Therapeutic Approaches to Cancer (ISBN 9781774630839) Zhang , J. et al., eds. – Optical Probes in Biology (ISBN 9781138199934)
Download or read book Shedding Light on the Nervous System Progress in Neurophotonics Research written by Jean-Claude Béïque and published by Frontiers Media SA. This book was released on 2022-07-01 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Optogenetics written by Hiromu Yawo and published by Springer Nature. This book was released on 2021-01-05 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, now in a thoroughly revised second edition, offers a comprehensive review of the rapidly growing field of optogenetics, in which light-sensing proteins are genetically engineered into cells in order to acquire information on cellular physiology in optical form or to enable control of specific network in the brain upon activation by light. Light-sensing proteins of various living organisms are now available to be exogenously expressed in neurons and other target cells both in vivo and in vitro. Cellular functions can thus be manipulated or probed by light. The new edition documents fully the extensive progress since publication of the first edition to provide an up-to-date overview of the physical, chemical, and biological properties of light-sensing proteins and their application in biological systems, particularly in neuroscience but also in medicine and the optical sciences. Underlying principles are explained and detailed information provided on a wide range of optogenetic tools for the observation and control of cellular signaling and physiology, gene targeting technologies, and optical methods for biological applications. In presenting the current status of optogenetics and emerging directions, this milestone publication will be a “must read” for all involved in research in any way related to optogenetics.
Download or read book All Optical Methods to Study Neuronal Function written by Eirini Papagiakoumou and published by Springer Nature. This book was released on 2023-02-20 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume provides an overview of the latest methods used to study neuronal function with all-optical experimental approaches, where light is used for both stimulation and monitoring of neuronal activity. The chapters in this book cover topics over a broad range, from fundamental background information in both physiology and optics in the context of all-optical neurophysiology experiments, to the design principles and hardware implementation of optical methods used for photoactivation and imaging. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and cutting-edge, All-Optical Methods to Study Neuronal Function is a valuable resource for researchers in various disciplines such as physics, engineering, and neuroscience. This book will serve as a guide to establish useful references for groups starting out in this field, and provide insight on the optical systems, actuators, and sensors. This is an open access book.
Download or read book Optogenetics written by Arash Kianianmomeni and published by . This book was released on 2016 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Zebrafish written by James F. Amatruda and published by Springer Nature. This book was released on 2023-09-05 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated edition introduces new tools, models, and analytic insights that position the zebrafish even more strongly as an engine of discovery for developmental and disease biology. Beginning with a section exploring detailed methods for use of zebrafish to model a variety of human diseases, the book continues by illuminating the key ongoing role of the fish model in studies of the vertebrate nervous system, tools and approaches using zebrafish to study stem cell and regenerative biology, as well as techniques in genetics and genomics. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Zebrafish: Methods and Protocols, Third Edition serves as an invaluable guide to propel advances in developmental biology, disease modeling, and regeneration research using zebrafish and medaka as model systems.
Download or read book Epigenetics to Optogenetics written by and published by BoD – Books on Demand. This book was released on 2022-08-31 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics, which deals with the study of heritable gene expression that takes place independent of changes in DNA sequence, and optogenetics, which deals with the study of genes expressed under the influence of light, are two emerging areas of study and research that have contributed immensely to our current knowledge of mechanisms and disease processes in humans. These disciplines are interrelated in the broader picture of biology and one can be used to change or modify the other. The complexity of the techniques involved in these disciplines often leads to a lack of proper understanding by researchers from other disciplines and the scientific community at large. As such, this book provides simple and easy-to-follow explanations of some of the most exciting areas of research in these disciplines.
Download or read book Cell Biology and Translational Medicine Volume 9 written by Kursad Turksen and published by Springer Nature. This book was released on 2020-08-27 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the ninth volume of a continuing series.
Download or read book Optogenetics A Roadmap written by Albrecht Stroh and published by Humana Press. This book was released on 2017-10-25 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the optogenetics workflow, and covers topics on viral vectors, targeting strategies, choice on opsins, animal models and readouts, and applications in systems neuroscience. This book shows readers how to identify the critical aspects of each methodological step, and how to determine the necessary level of complexity to address the particular research question. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and cutting-edge, Optogenetics: A Roadmap is a valuable guide for both the optogenetics novices and the experts.
Download or read book Tropism Mapping Modeling or Therapy Using Canine Adenovirus Type 2 CAV 2 Vectors in the CNS written by Eric J. Kremer and published by Frontiers Media SA. This book was released on 2021-03-26 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Scrum Book written by Jeff Sutherland and published by Pragmatic Bookshelf. This book was released on 2019-08-16 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building a successful product usually involves teams of people, and many choose the Scrum approach to aid in creating products that deliver the highest possible value. Implementing Scrum gives teams a collection of powerful ideas they can assemble to fit their needs and meet their goals. The ninety-four patterns contained within are elaborated nuggets of insight into Scrum’s building blocks, how they work, and how to use them. They offer novices a roadmap for starting from scratch, yet they help intermediate practitioners fine-tune or fortify their Scrum implementations. Experienced practitioners can use the patterns and supporting explanations to get a better understanding of how the parts of Scrum complement each other to solve common problems in product development. The patterns are written in the well-known Alexandrian form, whose roots in architecture and design have enjoyed broad application in the software world. The form organizes each pattern so you can navigate directly to organizational design tradeoffs or jump to the solution or rationale that makes the solution work. The patterns flow together naturally through the context sections at their beginning and end. Learn everything you need to know to master and implement Scrum one step at a time—the agile way.
Download or read book Photoswitching Proteins written by Sidney Cambridge and published by Humana. This book was released on 2016-09-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photoswitching Proteins: Methods and Protocols, focuses on proven applications of photoswitching proteins in cell and neurobiology. Optical approaches have been mostly embraced by the neurosciences to allow fast, high-resolution characterization and manipulation of single cells in complex neuronal tissue. These tools, including photoswitching of proteins, are now successfully used in almost all fields of biological research. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Photoswitching Proteins: Methods and Protocols highlights many of the possibilities for research based on light-inducible, high-resolution manipulation of biological systems.
Download or read book Optical Neural Interfaces written by Massimo De Vittorio and published by Frontiers Media SA. This book was released on 2019-11-01 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Elite Migrants South Asian Doctors in the UK written by Yasmin Ghazala Farooq and published by Transnational Press London. This book was released on 2020-11-13 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book makes a major contribution to the community cohesion literature and adds a new dimension to our understanding of community cohesion in the UK. Previous research in this area has remained overly focused on the experiences of low/semi skilled migrants. The author provides an analysis of her funded empirical research that investigated the first time the integration experiences of overseas-trained South Asian doctors in three different UK geographical locales. She reflects on their experiences from the point of migration to settlement in the UK society and describes this elite group as existing somewhere between privilege and marginalisation. The book highlights how identities are more plural than discourses of belonging often allow. “In this excellent work of scholarship, Farooq provides us with a rich and insightful account of the experiences of a remarkably important migrant group – South Asian doctors who came to Britain to work in the NHS. This rich and multifaceted work provides a vital and engaging account of this remarkable group. Essential reading for anyone interested in the role of migrant workers in the NHS, and in the experiences and challenges faced by migrants settling to Britain during the 1960s and 1970s.” – Robert Ford, Professor of Political Science, University of Manchester, UK “Dr Farooq’s research into the lives and contributions of South Asian doctors working in NHS GP practices in the North of England is insightful as well as timely. Her work examines the complex intersections between class, race and migration. The analysis are supplemented with some wonderful quotes by the doctors on how they responded to their migration journeys, and adapted to their local communities and the changing demands of working within the NHS. The research provides a unique insight into the experiences of different generations of South Asian GPs who contributed so much to our local communities. – Tarani Chandola, Professor of Medical Sociology, University of Manchester, UK “Often seen as a uniquely British institution, the NHS is really an international institution where international medical graduates, international nurses and migrant labour have contributed to it its values, its identity and its purpose. Yasmin Farooq, together with her contemporary Julian Simpson who both worked with me to document this history will ensure that future historians will acknowledge and recognise the hidden contribution of these architects and pioneers to British Society and the International NHS.” – Aneez Esmail, Professor of General Practice, University of Manchester, UK . Contents Foreword by Aneez Esmail Preface and Acknowledgements Introduction Chapter 1: The Context of Migration Chapter 2: Navigating the UK Medical System upon Arrival Chapter 3: Understanding Entrepreneurship within the General Practice Chapter 4: Integration and Sense of Belonging Chapter 5: Experiences of Racism and Coping Strategies Chapter 6: Discussion and Conclusions
Download or read book Emerging Horizons in Neuromodulation written by and published by Academic Press. This book was released on 2012-12-31 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of International Review of Neurobiology brings together cutting-edge research on neuromodulation. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery. - Brings together cutting-edge research on neuromodulation - Reviews current knowledge and understanding - Provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery
