Download or read book Oestrogen Receptors and Prolactin in Rat Mammary Tumour Development written by Marinus Aloysius Blankenstein and published by . This book was released on 1980 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Influences of Hormones in Tumor Development written by and published by . This book was released on 1979 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hormonal Regulation of Mammary Tumors written by Benjamin S. Leung and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept that hormones influence tumor growth originated in 1889 with the proposal of Albert Schinzinger who suggested that breast cancer is related to the ovaries. Several years later, Sir George Beatson observed that remission of disseminated breast cancer could be achieved in premenopausal patients by performing bilateral oophorectomy. As a result of the contri butions of Hedley Atkins, Charles Huggins and others, additive and ablative hormonal therapies have been widely used for the treatment of advanced breast cancers for several decades. Model systems to study the effects of hormones on growth and regression of breast tumors have been available for many years; however, the complexities of the hormonal environment have rendered in vivo studies difficult in man and experimental animals. Recently, the availability of long-term cultures of breast cancer cells has stimulated many investigators to use these cell lines to unravel the mechanisms of hormone action. Because of the extreme diversity and complexity of advances regarding the endocrinology of the breast and breast cancers, a multi-authored review was deemed necessary. It has been gratifying to receive contributions from many noted scholars. In Volume I of this monograph, the influence of steroid hormones and their antagonists upon normal and neoplastic tissues of the mammary gland are presented. In Volume II, the effects of peptide and other hormones are reviewed.
Download or read book Relation of Prolactin Estrogen GH and Protein Deficiency to Growth of DMBA induced Mammary Tumors in Rats written by Carol Joan Bradley and published by . This book was released on 1974 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Effects of Hormones on the Growth of Carcinogen induced Rat Mammary Carcinoma in Vitro written by Gloria M. Calaf De Iturri and published by . This book was released on 1975 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Effects of Ergocornine on Serum Prolactin Levels and Growth of Carcinogen induced Mamary Tumors in Female Rats written by Eldon E. Cassell and published by . This book was released on 1971 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Effects of Hormones and Drugs on the Growth of Carcinogen induced Mammary Tumors written by James L. Clark and published by . This book was released on 1972 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hormonal Regulation of Mammary Tumors written by Benjamin S. Leung and published by Springer London. This book was released on 1982 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dietary Estrogens and Hormone Dependent Mammary Cancer written by Kathey M. Verdeal and published by . This book was released on 1978 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Differential Growth of Enzyme dissociated and Non dissociated Rat Mammary Tumor Transplants Placed in Gland free and Gland containing Mammary Fat Pads written by Brenda P. Alston-Mills and published by . This book was released on 1984 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Effects of N nitrosomethylurea and Psychotropic Drugs on Rat Mammary Tumors Uterine Pathology and Endocrine Function written by Kathey M. Verdeal and published by . This book was released on 1982 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Mammary Gland written by Margaret C. Neville and published by Springer. This book was released on 1987-11-30 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Recent Advances in Prolactin Research written by Maria Diakonova, PhD and published by Springer. This book was released on 2014-12-03 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in Prolactin Research summarizes the current knowledge of prolactin (PRL), PRL receptor, PRL-dependent signaling pathways, the role of PRL in oncogenesis and PRL crosstalk with other oncogenic factors. The chapters are written by experts in these fields and focus on identifying and reviewing timely experimental findings that provide new insights into the expanding role of PRL in the pathophysiology associated with a variety of human conditions. Prolactin is a peptide hormone that is best known for its role in lactation. Prolactin also has an influence on hematopoiesis and angiogenesis, and is involved in the regulation of blood clotting through several pathways. Although PRL was discovered more than 80 years ago, the understanding of PRL signaling and its relationship to various pathologies is still very incomplete. PRL is not only a pituitary hormone with an important role in reproduction, but PRL also acts as a cytokine, modulating a wide variety of physiological processes. For example, data gathered during the last decade have demonstrated that locally produced PRL acts as the autocrine/paracrine factor and plays a contributory role during breast oncogenesis. In fact, the scientific and clinical communities have suggested that the manipulation of the PRL axis may lead to the successful treatment of breast cancer. However, recent work has demonstrated that the role of the PRL axis is much more complex than first envisaged.
Download or read book The Pineal Gland and Cancer written by C. Bartsch and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 979 pages. Available in PDF, EPUB and Kindle. Book excerpt: The link between the pineal gland and cancer is a rapidly emerging research field due to promising experimental and clinical trials with melatonin. The pineal gland acts as a transducer of environmental light to regulate rhythmic processes, including reproductive function in seasonally breeding animals and the entrainment of circadian rhythms, such as the sleep-wake cycle, in man. This book elucidates the physiological significance of the pineal gland and surveys phenomena and mechanisms of pineal - tumor interaction at the neuroendocrine, neuroimmune, neural, and molecular levels. Yet unidentified low-molecular-weight pineal substances with tumor-inhibiting capacity, a possible involvement of melatonin in electromagnetic field effects on cancer, and the oncotherapeutic potential of melatonin are also addressed. The encouraging results should incite further research to elucidate the exact nature of the link between the pineal gland and cancer for the benefit of patients.
Download or read book Pathology of Laboratory Rodents and Rabbits written by Stephen W. Barthold and published by John Wiley & Sons. This book was released on 2016-01-04 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its fourth edition, Pathology of Laboratory Rodents and Rabbits has become a standard text for veterinary pathologists, laboratory animal veterinarians, students, and others interested in these species. • The standard reference on the pathogenesis and cardinal diagnostic features of diseases of mice, rats, hamsters, gerbils, guinea pigs, and rabbits • Expanded coverage of rabbit disease, normal anatomic features, and biology • Over 450 color photographs illustrating gross and microscopic pathology • Companion website offering images from the text in PowerPoint
Download or read book Tamoxifen written by John A. Kellen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tamoxifen has persisted as a widely accepted and administered drug for almost 25 years. Following the many scientific papers and books on the subject, it has remained a very intriguing substance. This, perhaps, is the reason for another monograph on Tamoxifen. It is regrettably true that overviews, even when up to date after exhaustive research - the shibboleth of our cultures -, rapidly lose relevance with the passage of time. Scientists can sometimes be pictured as deep sea divers, who plunge into the unknown in search of a hitherto unknown world. Their descent is exciting, but eventually they must come up for air and integrate their experiences with others who also had to resurface. This book intends to collect and, where possible, to collate recent, but sometimes seemingly unrelated information. To quote Stephane Mallarme: "Everything in the world exists to end up in a book". Even if this is a tad cynical, it might not be far from the truth. If a little knowledge is a dangerous commodity, one can also add - tongue in cheek - that a vast amount of knowledge can be truly hazardous. It is likely that what might seem as entangled data is confusing, especially for those satisfied with the comfortable interpretation of Tamoxifen as an antiestrogen which has long been found insufficient. The complexity of its mechanisms and effects defies simple explanations and may even seem capricious, but only because of our ignorance.
Download or read book Mechanisms of Carcinogenesis written by Elizabeth K. Weisburger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.
