Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 123 Partition Coefficient 1 Octanol Water Slow Stirring Method written by OECD and published by OECD Publishing. This book was released on 2006-07-11 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes the slow-stirring method, which permits the determination of the 1-octanol/water partition coefficient (POW) values up to a log POW of 8.2. The partition coefficient between water and 1-octanol (POW) is defined as the ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 107 Partition Coefficient n octanol water Shake Flask Method written by OECD and published by OECD Publishing. This book was released on 1995-07-27 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a method to determine experimentally Pow values in the range log Pow between -2 and 4 (occasionally up to 5). This method can not be used with surface-active materials. The partition coefficient is defined as the ratio ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 117 Partition Coefficient n octanol water HPLC Method written by OECD and published by OECD Publishing. This book was released on 2004-11-23 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes the HPLC method, which permits to determine the partition coefficient (n-octanol/water) (Pow). Reverse phase HPLC is performed on analytical columns packed with a solid phase containing long hydrocarbon chains ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 305 Bioaccumulation in Fish Aqueous and Dietary Exposure written by OECD and published by OECD Publishing. This book was released on 2012-10-02 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a procedure for characterising the bioconcentration potential of substances in fish, using an aqueous (standard and minimised tests) or dietary exposure, under flow-through conditions (but semi-static regimes are ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 319A Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes RT HEP written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 319B Determination of in vitro intrinsic clearance using rainbow trout liver S9 sub cellular fraction RT S9 written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline (TG) describes the use of liver S9 sub-cellular fraction (RT-S9) of rainbow trout (Oncorhynchus mykiss) as a metabolising system to determine the clearance (CL, IN VITRO, INT ) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 105 Water Solubility written by OECD and published by OECD Publishing. This book was released on 1995-07-27 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes methods to determine the water solubility of test substances. The water solubility of a substance is the saturation mass concentration of the substance in water at a given temperature. This guideline addresses the ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 120 Solution Extraction Behaviour of Polymers in Water written by OECD and published by OECD Publishing. This book was released on 2000-01-21 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a method to analyse the solution/extraction behaviour of polymers in water, which uses the flask method with modifications. Three samples of 10 g of particles of the test substance are weighed into each of three vessels ...
Download or read book OECD Series on Testing and Assessment Guidance Document on Good In Vitro Method Practices GIVIMP written by OECD and published by OECD Publishing. This book was released on 2018-12-10 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 111 Hydrolysis as a Function of pH written by OECD and published by OECD Publishing. This book was released on 2004-11-23 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a laboratory test method to assess abiotic hydrolytic transformations of chemicals in aquatic systems at pH values normally found in the environment (pH 4 – 9). This Guideline is designed as a tiered approach; each tier ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 112 Dissociation Constants in Water written by OECD and published by OECD Publishing. This book was released on 1981-05-12 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes the methods allowing the determination of the dissociation constants in water. The dissociation is the reversible splitting into two or more chemical species which may be ionic. The determination of the dissociation ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 109 Density of Liquids and Solids written by OECD and published by OECD Publishing. This book was released on 2012-10-02 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline lists methods for determining the density of liquids and solids, giving only a succinct description of them. The density of a substance is the quotient of its mass and its volume and is expressed in SI units as kg/m3 at a ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 108 Complex Formation Ability in Water written by OECD and published by OECD Publishing. This book was released on 1981-05-12 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes the polarographic method. The ability of a substance to form complexes with metals can be assessed by means of polarographic techniques which allow the determination of stability constants for some complexes. The ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 103 Boiling Point written by OECD and published by OECD Publishing. This book was released on 1995-07-27 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes methods to determine the boiling point of test substances. The boiling point of a liquid is defined as the temperature (in K) at which the vapour pressure equals the standard atmospheric pressure 101.325 kPa. The ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 122 Determination of pH Acidity and Alkalinity written by OECD and published by OECD Publishing. This book was released on 2013-07-26 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes the procedure for the electronic determination of pH of an undiluted aqueous solution or dispersion, the pH of a dilution of a solution or dispersion in water, or the pH of a chemical diluted to end-use concentration ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 1 Test No 115 Surface Tension of Aqueous Solutions written by OECD and published by OECD Publishing. This book was released on 1995-07-27 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes methods to determine the surface tension (in N/m) of aqueous solutions. The methods are based on the measurement of the force which it is necessary to exert vertically on a stirrup or ring, in contact with the surface ...
Download or read book Toxicology of Fishes written by Kristine L. Willett and published by CRC Press. This book was released on 2024-02-06 with total page 1118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date, comprehensive toxicology handbook is devoted to the effects of environmental pollution on fish. Fish species represent nearly half of all vertebrates and have become important sentinels for environmental contamination and model organisms for understanding adverse outcomes from exposures. This new edition is written by recognized experts, and it highlights the significant research progress in fish toxicology that has resulted from rapid technological developments in analytical, biochemical, and genomic sciences. The book: Discusses fundamental topics such as toxicokinetics in fishes, processes governing biotransformation within these organisms, and reactive oxygen species and oxidative stress. Explains key target organ systems for chemical impacts in fish, such as the nervous and immune systems, and how fishes can develop resistance to chemical toxicity. Covers multi-transgenerational effects on fishes, epigenetics, proteomics and metabolomics, and adverse outcome pathways. Replacing the case studies in the first edition, this update delves into the impacts of microplastics, pharmaceuticals, and oil spills in dedicated final chapters. With nearly 200 illustrations and tables, this comprehensive reference work presents concepts in a way that is useful for both novices to and experts in the field of fish toxicology.
