Download or read book NuSAP a Novel Microtubule Associated Protein Involved in Mitotic Spindle Organization written by Tim Raemaekers and published by Leuven University Press. This book was released on 2003-09 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Vitamin D and bone, Linking the fields of vitamin D and bone with those of the nucleus and mitotic spindle, Nucleus structure and dynamics, Organization of the nucleus, Microtubules and associated proteins, Mitosis and spindle assembly, Control and mechanism of spindle formation and dynamics, Materials and methods, NuSAP, and novel MAP involved in spindle organization, NuSAP expression in cultured osteoblasts: regulation during development and by 1,25-dihydroxyvitamin D3, Analysis of NuSAP gene expression at the tissue level and chromosomal localization of human and mouse NuSAP, Developmentally regulated expression of NuSAP in the rat testis and mouse embryo, Chromosomal localization of human and mouse Nusap, General discussion and perspectives."
Download or read book Ras Superfamily Small G Proteins Biology and Mechanisms 2 written by Alfred Wittinghofer and published by Springer. This book was released on 2014-09-26 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. In this volume the focus lies on the Rab, Ran and Arf subfamily members. As in Volume 1, the book is written by international renowned scientists in the field of small G-proteins. In elaborate reviews, biochemistry, structure, function and G-protein - effector interactions are described. Together with Volume 1 this book provides an comprehensive state-of-the-art work on small G-proteins (GTPases). It is written for Graduates and Professors in Biochemistry and Cell Biology interested in the mechanism and function of small G-proteins but are extremely valuable for those who want to move into the field.
Download or read book Proteins of the Nucleolus written by Danton H O'Day and published by Springer Science & Business Media. This book was released on 2013-02-26 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure and function in normal, stressed and diseased cells. The goal of this work is to provide special insight into the nucleolus of the past, present and future, as well its regulation, translocation, and biomedical function. A multitude of topics are introduced and discussed in detail, including nucleologenesis, nucleolar architecture, nucleolar targeting, retention, anchoring, translocation, and the relationship between the nucleolus and cancer. This book also brings together work from several different species, from human to Drosophila to Dictyostelium and other eukaryotic microbes. The final chapter summarizes some of the issues brought up in the various chapters with a view to future research. This book supports the continued emergence of the nucleolus as a dynamic intranuclear region that oversees a vast diversity of events.
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 1666 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Download or read book Biology Driven Targeted Therapy of Pediatric Soft Tissue and Bone Tumors Current Opportunities and Future Challenges written by Thomas G. P. Grünewald and published by Frontiers Media SA. This book was released on 2016-04-05 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in the understanding of the biological basis of pediatric soft-tissue and bone tumors, especially owing to the advent of “omics” technologies, have led to an exponential increase in the current knowledge on the genetic and cellular patho-mechanisms that drive these diseases. This offers the unprecedented opportunity to develop and implement targeted therapies such as monoclonal antibodies, small molecules, oncolytic viruses, and immunotherapies in standard and/or personalized treatment regimens. However, to date only a few examples document a successful translation of discoveries from the bench to the bedside. Recent international expert congresses further emphasize the urgent need for a more rapid and especially more successful translational process. Hence, we strongly believe that a Frontiers Research Topic aiming at this aspect would fit just in time and be relevant for a broad readership. This Frontiers Research Topic intended to provide a platform for active and interdisciplinary discussion, to summarize current state-of-the-art knowledge on all basic research and translational aspects in pediatric soft-tissue and bone tumors, and to offer new perspectives on how to further promote and accelerate the translational process. It comprises high-quality original articles and timely reviews.
Download or read book Advances in Non Alcoholic Fatty Liver Disease Therapeutics Pathogenic Mechanisms and Targets written by Ana Blas-García and published by Frontiers Media SA. This book was released on 2022-12-05 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Physiological Study of Presenilins and Baces Two Proteases Involved in the Pathogenesis of Alzheimer s Disease written by Jos Tournoy and published by Leuven University Press. This book was released on 2006 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Presenilins and Nicastrin are Components of the Secretease Complex Involved in APP and Notch Processing written by An Herreman and published by Leuven University Press. This book was released on 2003-12 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a Ph.D. dissertation. Dementia is a major cause of disability and mortality. The most frequent type of dementia is Alzheimer's disease, accounting for about 70% of all dementia cases. Worldwide, about 20 million people suffer from Alzheimer's disease. With the increasing number of elderly in the world, Alzheimer's disease represents more and more a major health problem with an enormous impact on individuals, families, the health care system, and the society. Therefore, it is imperative that we understand the etiologies, the risk factors and the pathogenic mechanisms involved in Alzheimer's disease in order to develop effective treatments that ameliorate or even prevent this illness."
Download or read book Protein Phosphatase 1 Binding Motifs written by Paulina Wakula and published by Leuven University Press. This book was released on 2006 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms of Mitotic Chromosome Segregation written by J. Richard McIntosh and published by MDPI. This book was released on 2018-03-23 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Mechanisms of Mitotic Chromosome Segregation" that was published in Biology
Download or read book Variation in Sodium Regulating Genes in Relation to Blood Pressure and Associated Phenotypes in Caucasians and Chinese written by Jiguang Wang and published by Leuven University Press. This book was released on 2004-09 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ciz As a Fusion Partner for Tet proteins in Leukemia written by Hilde Janssen and published by Leuven University Press. This book was released on 2006-12-30 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Study of the Endocrine and Metabolic Dysfunction and Assessment of Hormonal Interventions in a Novel in Vivo Experimental Model of Critical Illness written by Frank Weekers and published by Leuven University Press. This book was released on 2003 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Protein bound Solute P cresol written by Bert Bammens and published by Leuven University Press. This book was released on 2005 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book NIPP1 an Interactor of Protein Phosphatase 1 Displays Endoribonuclease and Transcriptional Repression Activities written by Qiming Jin and published by Leuven University Press. This book was released on 2004 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a Ph.D. dissertation. This thesis deals with the eukaryotic protein NIPP1 (Nuclear Inhibitor of Protein Phosphate-1), which was initially described by the host laboratory in 1992 and still is the major focus of its research efforts. The first part of the introduction describes our current insights into the structure and function of NIPP1, with the exception of aspects that directly deal with this doctoral project. For reasons of clarity, the data are presented in a logical manner, which implies that they are not necessarily presented according to their order of discovery. In the final sections of the introduction, a brief overview will be given of the state of the art of the `structure and function of ribonucleases' and `transcriptional repression mechanisms,' two topics that directly related to this research project. Contents include: Introduction, The Structure and Function of NIPP1, The Structure and Function of Ribonucleases, Transcriptional Repression in Eukaryotes, Aims and Strategies, Materials and Methods, Results and Discussions, Mapping of the RNA-binding and Endoribonuclease Domain of NIPP1, Screening for Proteins that Interact with the C-Terminal domain of NIPP1."
Download or read book Modulation of CFTR and ENaC Channel Function by Interacting Proteins and Trafficking written by Lishuang Cao and published by Leuven University Press. This book was released on 2005 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biochemical Characterization and Validation of the Yeast Saccharomyces Cerevisiae as Model System for the Function of Human Protein Tau written by Tom Vandebroek and published by Leuven University Press. This book was released on 2006-09 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
