Download or read book nus da prova no direito processual penal brasileiro written by Gustavo Henrique Righi Ivahy Badaró and published by . This book was released on 2001 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Translational Medicine written by Joy A. Cavagnaro and published by CRC Press. This book was released on 2021-11-26 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Download or read book UNCITRAL Conciliation Rules written by United Nations Commission on International Trade Law and published by New York : United Nations. This book was released on 1981 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Power and Pawn written by Ann Pescatello and published by Praeger. This book was released on 1976-06-25 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of the role of Iberian women in Europe, Asia, Africa and America as well as those indigenous cultures influenced by Iberians (the people of present-day Spain and Portugal).
Download or read book Nature and History in Modern Italy written by Marco Armiero and published by Ohio University Press. This book was released on 2010-08-31 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marco Armiero is Senior Researcher at the Italian National Research Council and Marie Curie Fellow at the Institute of Environmental Sciences and Technologies, Universitat Aut(noma de Barcelona. He has published extensively on-Italian environmental history and edited Views from the South: Environmental Stories from the Mediterranean World. --
Download or read book West Roman Vulgar Law written by Ernst Levy and published by . This book was released on 1951 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Soft Cage written by Christian Parenti and published by Basic Books. This book was released on 2007-10-15 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: On a typical day, you might make a call on a cell phone, withdraw money at an ATM, visit the mall, and make a purchase with a credit card. Each of these routine transactions leaves a digital trail for government agencies and businesses to access. As cutting-edge historian and journalist Christian Parenti points out, these everyday intrusions on privacy, while harmless in themselves, are part of a relentless (and clandestine) expansion of routine surveillance in American life over the last two centuries-from controlling slaves in the old South to implementing early criminal justice and tracking immigrants. Parenti explores the role computers are playing in creating a whole new world of seemingly benign technologies-such as credit cards, website "cookies," and electronic toll collection-that have expanded this trend in the twenty-first century. The Soft Cage offers a compelling, vitally important history lesson for every American concerned about the expansion of surveillance into our public and private lives.
Download or read book Preclinical Safety Evaluation of Biopharmaceuticals written by Joy A. Cavagnaro and published by John Wiley & Sons. This book was released on 2013-03-07 with total page 1012 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The goal is to provide a comprehensive reference book for the preclinicaldiscovery and development scientist whose responsibilities span target identification, lead candidate selection, pharmacokinetics, pharmacology, and toxicology, and for regulatory scientists whose responsibilities include the evaluation of novel therapies." —From the Afterword by Anthony D. Dayan Proper preclinical safety evaluation can improve the predictive value, lessen the time and cost of launching new biopharmaceuticals, and speed potentially lifesaving drugs to market. This guide covers topics ranging from lead candidate selection to establishing proof of concept and toxicity testing to the selection of the first human doses. With chapters contributed by experts in their specific areas, Preclinical Safety Evaluation of Biopharmaceuticals: A Science-Based Approach to Facilitating Clinical Trials: Includes an overview of biopharmaceuticals with information on regulation and methods of production Discusses the principles of ICH S6 and their implementation in the U.S., Europe, and Japan Covers current practices in preclinical development and includes a comparison of safety assessments for small molecules with those for biopharmaceuticals Addresses all aspects of the preclinical evaluation process, including: the selection of relevant species; safety/toxicity endpoints; specific considerations based upon class; and practical considerations in the design, implementation, and analysis of biopharmaceuticals Covers transitioning from preclinical development to clinical trials This is a hands-on, straightforward reference for professionals involved in preclinical drug development, including scientists, toxicologists, project managers, consultants, and regulatory personnel.
Download or read book Automotive Ethernet written by Kirsten Matheus and published by Cambridge University Press. This book was released on 2015 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn how automotive Ethernet is revolutionizing in-car networking from the experts at the core of its development. Providing an in-depth account of automotive Ethernet, from its background and development, to its future prospects, this book is ideal for industry professionals and academics alike.
Download or read book Noble Savages written by Napoleon A. Chagnon and published by Simon and Schuster. This book was released on 2014-02-18 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biography.
Download or read book The Fishes of Lake Valencia Caracas and of the Rio Tuy at El Concejo Venezuela written by Carl H Eigenmann and published by . This book was released on 1920 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Contemporary Argentine Cinema written by David William Foster and published by University of Missouri Press. This book was released on 1992 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Foster discusses ten Argentine films, including Kiss of the Spider Woman, The Official Story, and Man Facing Southeast to examine the transformation of social topics into motion pictures and the relationship between commercial filmmaking strategies and Argentine redemocratization."--Publishers website.
Download or read book Imperial Migrations written by E. Morier-Genoud and published by Springer. This book was released on 2012-12-15 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume investigates what role colonial communities and diaspora have had in shaping the Portuguese empire and its heritage, exploring topics such as Portuguese migration to Africa, the Ismaili and the Swiss presence in Mozambique, the Goanese in East Africa, the Chinese in Brazil, and the history of the African presence in Portugal.
Download or read book Introduction to Animal Rights written by Gary Francione and published by Temple University Press. This book was released on 2010-07-29 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Argues that the way humans treat animals results from the contradiction between the ideas that animals have some rights, but that they are also property, and offers ways to resolve the conflict.
Download or read book Habermas and Contemporary Society written by J. Sitton and published by Springer. This book was released on 2003-08-15 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last four decades Jürgen Habermas has forged an innovative and much-discussed theory of contemporary capitalist society. Building on Max Weber's thesis that the dynamic of capitalism actually erodes individual freedom and the meaningfulness of social life - famously resulting in a culture of 'specialists without spirit, sensualists without heart' - Habermas traces contemporary social conflict to resistance to this dynamic by a variety of social groups. His theory of 'communicative action' attempts to show the possibilities in contemporary society for moving toward a more balanced social life that, unlike other political currents today, would not sacrifice the truly progressive features of complex modern societies. By marginalizing methodological and other more specialized theoretical concerns, this book focuses on Habermas's substantive portrayal of contemporary society and its discontents.
Download or read book The Global Encyclopaedia of Informality Volume 2 written by Alena Ledeneva and published by UCL Press. This book was released on 2018-01-17 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alena Ledeneva invites you on a voyage of discovery to explore society’s open secrets, unwritten rules and know-how practices. Broadly defined as ‘ways of getting things done’, these invisible yet powerful informal practices tend to escape articulation in official discourse. They include emotion-driven exchanges of gifts or favours and tributes for services, interest-driven know-how (from informal welfare to informal employment and entrepreneurship), identity-driven practices of solidarity, and power-driven forms of co-optation and control. The paradox, or not, of the invisibility of these informal practices is their ubiquity. Expertly practised by insiders but often hidden from outsiders, informal practices are, as this book shows, deeply rooted all over the world, yet underestimated in policy. Entries from the five continents presented in this volume are samples of the truly global and ever-growing collection, made possible by a remarkable collaboration of over 200 scholars across disciplines and area studies. By mapping the grey zones, blurred boundaries, types of ambivalence and contexts of complexity, this book creates the first Global Map of Informality. The accompanying database (www.in-formality.com) is searchable by region, keyword or type of practice, so do explore what works, how, where and why! Praise for Global Encyclopaedia of Informality ‘The Global Informality Project unveils new ways of understanding how the state functions and ways in which civil servants and citizens adapt themselves to different local contexts by highlighting the diversity of the relationships between state and society. The project is of great interest to policymakers who want to imagine solutions that are benefi cial for all, but sufficiently pragmatic to ensure a seamless implementation, particularly in the field of cross-border trade in developing countries.’ - Kunio Mikuriya, Secretary General of the World Customs Organisation, Brussels ‘An extremely interesting and stimulating collection of papers. Ledeneva’s challenging ideas, first applied in the context of Russia’s economy of shortage, came to full blossom and are here contextualized by practices from other countries and contemporary systems. Many original and relevant practices were recognized empirically in socialist countries, but this book shows their generality.’ - János Kornai, Allie S. Freed Professor of Economics Emeritus at Harvard and Professor Emeritus at Corvinus University of Budapest ‘Alena Ledeneva’s Global Encyclopedia of Informality is a unique contribution, providing a global atlas of informal practices through the contributions of over 200 scholars across the world. It is far more rewarding for the reader to discover how commonalities of informal behavior become apparent through this rich texture like a complex and hidden pattern behind local colors than to presume top down universal benchmarks of good versus bad behavior. This book is a plea against reductionist approaches of mathematics in social science in general, and corruption studies in particular and makes a great read, as well as an indispensable guide to understand the cultural richness of the world.’ - Alina Mungiu-Pippidi, Professor of Democracy Studies, Hertie School of Governance, Berlin ‘Transformative scholarship in method, object, and consequence. Ledeneva and her networked expertise not only enable us to view the informal comparatively, but challenge conventionally legible accounts of membership, markets, domination and resistance with these rich accounts from five continents. This project offers nothing less than a social scientific revolution… if the broader scholarly community has the imagination to follow through. And by globalizing these informal knowledges typically hidden from view, the volumes’ contributors will extend the imaginations of those business consultants, movement mobilizers, and peace makers who can appreciate the value of translation from other world regions in their own work.’ Michael D. Kennedy, Professor of Sociology and International and Public Aff irs, Brown University and author of Globalizing Knowledge ‘Don’t mistake these weighty volumes for anything directory-like or anonymous. This wonderful collection of short essays, penned by many of the single best experts in their fields, puts the reader squarely in the kinds of conversations culled only after years of friendship, trust, and with the keen eye of the practiced observer. Perhaps most importantly, the remarkably wide range of offerings lets us “de-parochialise” corruption, and detach it from the usual hyper-local and cultural explanations. The reader, in the end, is the one invited to consider the many and striking commonalities.’ Bruce Grant, Professor at New York University and Chair of the US National Council for East European and Eurasian Research
Download or read book The End of Privacy written by Reg Whitaker and published by ReadHowYouWant.com. This book was released on 2010-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in paperback, a sobering look at the threats to privacy posed by the new information technologies. Called ''one of the best books yet written on the new information age'' by Kirkus Reviews and now available in paperback, The End of Privacy shows how vast amounts of personal information are moving into corporate hands. Once there, this data can be combined and used to develop electronic profiles of individuals and groups that are potentially far more detailed, and far more intrusive, than the files built up in the past by state police and security agencies. Reg Whitaker shows that private e-mail can be read; employers can monitor workers' every move throughout the work day; and the U.S. Treasury can track every detail of personal and business finances. He goes on to demonstrate that we are even more vulnerable as consumers. From the familiar - bar-coding, credit and debit cards, online purchases - to the seemingly sci - -''smart cards'' that encode medical and criminal records, and security scans that read DNA - The End of Privacy reveals how ordinary citizens are losing control of the information about them that is available to anyone who can pay for it.
