Download or read book Nuclear Cytoplasmic Interactions in the Cell Cycle written by Gary Whitson and published by Elsevier. This book was released on 2012-12-02 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear-Cytoplasmic Interactions in the Cell Cycle

Download or read book Cell Cycle Regulation written by James R. Jr. Jeter and published by Elsevier. This book was released on 2012-12-02 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Cycle Regulation describes the interaction of the nuclear genome, the cytoplasmic pools, the organelles, the cell surface, and the extracellular environment that govern the cell cycle regulation. Comprised of 12 chapters, this book includes cell cycle regulation around nuclear chromatin modulation and some aspects of chromatin modification and its effects on gene expression. The opening chapters describe the macromolecular structure of chromatin subunits and the types and kinds of postsynthetic modifications occurring on histones, such as acetylation, methylation, and phosphorylation. The subsequent chapter deals extensively on histone phosphorylation, especially histone H1, H1M, H2A, and H3, during the cell cycle. Another chapter describes a selective histone leakage from nuclei during isolation accounting for the role of histone acetylation and phosphorylation in gene expression. This book goes on examining the assembly of microtubules and structural analysis on the regulatory role of calcium into a pattern for mitosis regulation. Other chapters discuss the methods used to measure intracellular pH changes as a function of the cell cycle of Physarum and the quantitative and qualitative changes taking place during the various phases of the cell cycle. The use of mammalian cell fusion to study cell cycle regulation and the protein synthesis regulation during the cell cycle in Chlamydomonas reinhardi are then discussed. The final chapters focus on the regulation of expression of an inducible structural gene during the cell cycle of the green alga Chlorella. The chapters provide evidence for a model of positive and negative oscillatory control of inducible gene expression. An analysis of the expression of cytoplasmic genes as a function of the cell cycle using pedigrees of a large number of individual yeast cells is also included. This book will appeal to a wide variety of life scientists and to molecular, cellular, and developmental biologists.

Download or read book Essentials of Medical Biochemistry written by Chung Eun Ha and published by Academic Press. This book was released on 2011-01-28 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert biochemist N.V. Bhagavan’s new work condenses his successful Medical Biochemistry texts along with numerous case studies, to act as an extensive review and reference guide for both students and experts alike. The research-driven content includes four-color illustrations throughout to develop an understanding of the events and processes that are occurring at both the molecular and macrolecular levels of physiologic regulation, clinical effects, and interactions. Using thorough introductions, end of chapter reviews, fact-filled tables, and related multiple-choice questions, Bhagavan provides the reader with the most condensed yet detailed biochemistry overview available. More than a quick survey, this comprehensive text includes USMLE sample exams from Bhagavan himself, a previous coauthor. Clinical focus emphasizing relevant physiologic and pathophysiologic biochemical concepts Interactive multiple-choice questions to prep for USMLE exams Clinical case studies for understanding basic science, diagnosis, and treatment of human diseases Instructional overview figures, flowcharts, and tables to enhance understanding

Download or read book Computational Medicine Public Health And Biotechnology Building A Man In The Machine Proceedings Of The First World Congress In 3 Parts written by Diana J Vincent and published by World Scientific. This book was released on 1996-07-03 with total page 1630 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three volume series represents a selected and refereed collection of papers contributed by the participants of the First World Congress on Computational Medicine, Public Health, and Biotechnology, held in 1994 at Austin, Texas. Over 500 individuals, from 30 countries attended this meeting. In addition, this collection contains a number of papers from the Australian CSIRO High Performance Computing Meeting held that same year.

Download or read book Principles of Cloning written by Jose Cibelli and published by Academic Press. This book was released on 2013-09-24 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Cloning, Second Edition is the fully revised edition of the authoritative book on the science of cloning. The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine. Beginning with the history and theory behind cloning, the book goes on to examine methods of micromanipulation, nuclear transfer, genetic modification, and pregnancy and neonatal care of cloned animals. The cloning of various species—including mice, sheep, cattle, and non-mammals—is considered as well. The Editors have been involved in a number of breakthroughs using cloning technique, including the first demonstration that cloning works in differentiated cells done by the Recipient of the 2012 Nobel Prize for Physiology or Medicine – Dr John Gurdon; the cloning of the first mammal from a somatic cell – Drs Keith Campbell and Ian Wilmut; the demonstration that cloning can reset the biological clock - Drs Michael West and Robert Lanza; the demonstration that a terminally differentiated cell can give rise to a whole new individual – Dr Rudolf Jaenisch and the cloning of the first transgenic bovine from a differentiated cell – Dr Jose Cibelli. The majority of the contributing authors are the principal investigators on each of the animal species cloned to date and are expertly qualified to present the state-of-the-art information in their respective areas. First and most comprehensive book on animal cloning, 100% revised Describes an in-depth analysis of current limitations of the technology and research areas to explore Offers cloning applications on basic biology, agriculture, biotechnology, and medicine

Download or read book Genetic Expression in the Cell Cycle written by G.M. Padilla and published by Elsevier. This book was released on 2012-12-02 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Expression in the Cell Cycle provides an understanding of the molecular mechanisms that govern the expression of genetic information during the cell cycle. The initial five chapters describe the intimate relationships between the supramolecular complexes that form the basic structure of chromatin. Emphasis is placed on the dynamics of cycle-dependent changes in the structural organization of some of these components. Subsequent chapters demonstrate that small nuclear RNAs (SnRNA) are actively involved in gene regulation in eukaryotic cells; discuss the relationship between cell cycle regulation in the yeast Saccharomyces cerevisiae and transcription of ribosomal RNA genes; and describe the use of conditional lethal mutants to study the regulation of the cell cycle of eukaryotic cells. The remaining chapters discuss the concepts and methodologies employed to isolate and study specific cell cycle mutants of S. cerevisiae; the antiproliferative effect of interferon on cultured human fibroblasts; and the role of cell membrane and related subcellular elements in the control of proliferation, differentiation, and cell cycle kinetics.

Download or read book Animal Breeding written by A.E. Clark and published by Routledge. This book was released on 2021-12-24 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text part offers a review of the research and developing technologies in the expanding areas of genetics, embryology, and molecular biology from experts in the various fields. It includes sections covering manipulation of the embryo, and the mapping and engineering of the genome, as well as information on nuclear transfer and the development of xenotransplantation. Possibilities for future research and development are also considered.

Download or read book The Eukaryotic Cell Cycle written by J. A. Bryant and published by Taylor & Francis US. This book was released on 2008 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by respected researchers, this is an excellent account of the eukaryotic cell cycle that is suitable for graduate and postdoctoral researchers. It discusses important experiments, organisms of interest and research findings connected to the different stages of the cycle and the components involved.

Download or read book Challenges in Delivery of Therapeutic Genomics and Proteomics written by Ambikanandan Misra and published by Elsevier. This book was released on 2010-09-09 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delivery of therapeutic proteomics and genomics represent an important area of drug delivery research. Genomics and proteomics approaches could be used to direct drug development processes by unearthing pathways involved in disease pathogenesis where intervention may be most successful. This book describes the basics of genomics and proteomics and highlights the various chemical, physical and biological approaches to protein and gene delivery. Covers a diverse array of topics from basic sciences to therapeutic applications of proteomics and genomics delivery Of interest to researchers in both academia and industry Highlights what’s currently known and where further research is needed

Download or read book The Cell Cycle written by G. M. Padilla and published by Academic Press. This book was released on 2013-09-11 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cell Cycle: Gene Enzyme Interactions presents the primary regulatory mechanisms of the cell cycle. This book provides theoretical and methodological discussions concerning cell cycles. Organized into 17 chapters, this book begins with an overview of cell evolution and thermodynamics. This text then examines the regulation of initiation of chromosome replication, and the coordination between this event and cell division, in Escherichia coli. Other chapters consider the operon model for the control of genetic expression in bacterial cells, which provides an understanding of the regulatory mechanisms of gene function. This book discusses as well the observations and experiments on the timing of events in the cell cycles of some bacteria and attempts to provide explanations in terms of established control systems. The final chapter deals with DNA markers, which serve as a convenient starting point for exploring the general principles of cell cycle markers. This book is a valuable resource for cell biologists.

Download or read book Nuclear Cytoplasmic Transport written by Weidong Yang and published by Springer. This book was released on 2018-07-27 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dysfunction of nuclear-cytoplasmic transport systems has been associated with many human diseases. Thus, understanding of how functional this transport system maintains, or through dysfunction fails to maintain remains the core question in cell biology. In eukaryotic cells, the nuclear envelope (NE) separates the genetic transcription in the nucleus from the translational machinery in the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded on the NE selectively mediate the bidirectional trafficking of macromolecules such as RNAs and proteins between these two cellular compartments. In this book, the authors integrate recent progress on the structure of NPC and the mechanism of nuclear-cytoplasmic transport system in vitro and in vivo.

Download or read book In Vitro Fertilization and Embryo Transfer in Primates written by Don P. Wolf and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a genuine honor and a privilege of distinction to provide the foreword for the proceedings that follow. This marvelous symposium reflects the unique qualities of its two principal sponsors. Whenever the Oregon Regional Primate Research Center is involved in matters of science, we see a consistent record of exceptional quality in both the work is unequaled and the people who do it. Likewise, Serono Symposia, USA in assuring a world-class speakers' forum, utterly without taint of commercial influence. The proceedings published herein are a remarkable testimony, not only to the contributors, but to Drs. Brenner, Wolf, Stouffer, and Burnett, who have shepherded its conception, presentation, and publication. Readers will notice immediately one of the universal strengths of this total composition; that is, the diversity of investigational interests among attendees. Presentations on the core topic of primate in vitro fertilization and embryo transfer were joined by specialist presentations in related areas, including human-assisted reproductive technologies, reproductive physiology of the great apes, sperm biology, implantation mechanisms, cryobiology, coculture systems for embryogenesis, micromanipulation technologies, and genetic diagnosis of heritable diseases in the pre embryo. Even though pro-fertility issues understandably dominated this forum, there was significant attention given to fertility-control research, especially the role of primates in this endeavor (more on this subject below).

Download or read book Chromosomal Nonhistone Protein written by L. S. Hnilica and published by CRC Press. This book was released on 2018-12-20 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second volume of the Chromosomal Nonhistone Proteins treatise is dedicated in its entirety to the immunobiology of these proteins. Since immunological methods are adding rapidly to our knowledge of the specificity and intranuclear localization of chromosomal nonhistone proteins, a collection of chapters dealing with various aspects of this important area was judged appropriate.

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1764 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Brenner s Encyclopedia of Genetics written by Stanley Maloy and published by Academic Press. This book was released on 2013-03-03 with total page 4360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike. Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries. This 7-volume set represents a 25% expansion from the first edition, with over 1600 articles encompassing this burgeoning field Thoroughly up-to-date, with many new topics and subfields covered that were in their infancy or not inexistence at the time of the first edition. Timely coverage of emergent areas such as epigenetics, personalized genomic medicine, pharmacogenetics, and genetic enhancement technologies Interdisciplinary and global in its outlook, as befits the field of genetics Brief articles, written by experts in the field, which not only discuss, define, and explain key elements of the field, but also provide definition of key terms, suggestions for further reading, and biographical sketches of the key people in the history of genetics

Download or read book Eukaryotic Cell Genetics written by John Morrow and published by Elsevier. This book was released on 2012-12-02 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eukaryotic Cell Genetics reviews the state of knowledge in somatic cell genetics. The book begins by discussing the development of somatic cell genetics, focusing on the estimation of mutation rates in mammalian cells, with frequent reference to the use of drug resistance as a selective character. It then considers some of the specific properties of such variants in order to understand their molecular basis. The subsequent chapters examine the properties of specific types of auxotrophic variants; the means by which eukaryotic cells may be reassembled to give rise to viable cellular composites; gene regulation in eukaryotic organisms; and chromosome mapping. The discussions also include differentiation in cultured cells; neoplastic transformation; the modulation of gene expression in cultured cells; mutation induction in cultured cells; applications of cell culture; and the mechanism of cellular aging. This book is intended for researchers in the fields of genetics and molecular biology, nonspecialists interested in what is happening in a very exciting area of biology, and students at the graduate level in cell biology.

Download or read book Cell Biology of Physarum and Didymium V2 written by Henery Aldrich and published by Elsevier. This book was released on 2012-12-02 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Biology of Physarum and Didymium, Volume II: Differentiation, Metabolism, and Methodology summarizes important experimental research using Physarum and Didymium for developmental and cellular studies. This book is organized into three parts, encompassing 28 chapters that cover the differentiation, metabolism, and experimental techniques for cellular studies. After presenting an introduction to some aspects of developmental biology, this volume describes the ultrastructure and physiology of sporulation, spore germination, encystment, excystment, spherulation, and spherule germination. This is followed by a discussion on regulatory events leading to morphogenesis and on biochemical, physiological, and structural data on the amoeboid stage. The second part focuses on metabolic aspects. This includes metabolic characteristics of myxomycetes; the formation of nucleotides in Physarum by de novo synthesis and from nucleic acid degradation products; and radiation and radiomimetic agents on myxomycete species. Considerable chapters in the concluding part are devoted to procedures and protocol for isolation of cell components from Physarum and Didymium species. This volume also evaluates some techniques, including electron microscopy, time-lapse microcinematography, phase-contrast microscopy, Feulgen staining, and culture methods. The concluding chapters examine the preparation, isolation, and characterization of ribonucleic acid, histone, plasmodial polysaccharides, myosin, actins, and fragmin. The book will serve as a frequent, single reference source to brief cell biologists on the primary research on Physarum and Didymium. It will also be a good source for graduate students in cell biology and perhaps in other graduate courses.