Download or read book New Insights Into PEXEL mediated Protein Export in Plasmodium Falciparum The Role of N terminal Acetylation written by Sophia Deil and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book News Insights Into PEXEL mediated Protein Export in Plasmodium Falciparum written by Sophia Deil and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Insights Into the Biology of the Plasmodium Falciparum Nucleus Using Transgenic Cell Lines written by Johanna Wetzel and published by . This book was released on 2011 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Apicomplexan Parasites written by Katja Becker and published by John Wiley & Sons. This book was released on 2011-01-19 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is the first dealing with the discovery of drugs directed against apicomplexan parasites. Amongst others, this group of endoparasites includes the causative agents of Malaria, Toxoplasmosis, and Babesiosis, the latter occurring mainly in animals. Written by renowned scientific experts from academia and industry, the book focuses on currentdrug development approaches for all apicomplexan diseases making it appealing to a large audience, ranging from research labs in academia to the human and veterinarian pharmaceutical industry. This work is the second volume of the new book series 'Drug Discovery in Infectious Diseases', edited by Prof. Dr Paul M. Selzer.
Download or read book Proteases in Physiology and Pathology written by Sajal Chakraborti and published by Springer. This book was released on 2017-09-14 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a multidisciplinary approach, this book describes the biochemical mechanisms associated with dysregulation of proteases and the resulting pathophysiological consequences. It highlights the role and regulation of different types of proteases as well as their synthetic and endogenous inhibitors. The role of proteases was initially thought to be limited to general metabolic digestion. However, we now know that the role of protein breakdown is much more complex, and proteases have multiple functions: they are coupled to turnover and can affect protein composition, function and synthesis. In addition to eliminating abnormal proteins, breakdown has many modulatory functions, including activating and inactivating enzymes, modulating membrane function, altering receptor channel properties, affecting transcription and cell cycles and forming active peptides. The ubiquity of proteases in nature makes them an important target for drug development. This in-depth, comprehensive is a valuable resource for researchers involved in identifying new targets for drug development. With its multidisciplinary scope, it bridges the gap between fundamental and translational research in the biomedical and pharmaceutical industries, making it thought-provoking reading for scientists in the field.
Download or read book Theileria written by Dirk Dobbelaere and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: The deadly nature of the Theileria parasite and the exquisite cunning, displayed when survival strategies are called for, inspire both awe and fascination, if not admiration, among field and laboratory scientists. Its negative impact on livestock production with resulting economical losses, however, undoubtedly affects the quality of human life. This book will provide detailed insight into the state-of-the art research, ongoing in different laboratories, aimed at unravelling the intricacies and molecular basis of the parasite as well as host-parasite interactions, that govern the immune responses and pathogenesis of Theileriosis. Theileria, volume three of "World Class Parasites", is written for researchers, students and scholars who enjoy reading research that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. It is intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. It integrates vector, pathogen and host biology and celebrates the diversity of approach that comprises modern parasitological research.
Download or read book The Biochemistry of Parasites written by Federation of European Biochemical Societies. Meeting and published by Pergamon. This book was released on 1981 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pathophysiological Aspects of Proteases written by Sajal Chakraborti and published by Springer. This book was released on 2017-11-15 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the multifaceted field of protease in the cellular environment and focuses on the recently elucidated functions of complex proteolytic systems in physiology and pathophysiology. Given the breadth and depth of information covered in the respective contributions, the book will be immensely useful for researchers working to identify targets for drug development. Multidisciplinary in scope, the book bridges the gap between fundamental and translational research, with applications in the biomedical and pharmaceutical industry, making it a thought-provoking read for basic and applied scientists engaged in biomedical research. Proteases represent one of the largest and most diverse families of enzymes known, and we now know that they are involved in every aspect of a given organism’s life functions. Under physiological conditions, proteases are regulated by their endogenous inhibitors. However, when the activity of proteases is not correctly regulated, disease processes such as tumour progression, vascular remodelling, atherosclerotic plaque progression, ulcer, rheumatoid arthritis, Alzheimer’s disease and inflammation can result. Many infective microorganisms require proteases for replication or use them as virulence factors, which has facilitated the development of protease-targeted therapies for a variety of parasitic diseases.
Download or read book Methods to Assess DNA Damage and Repair written by Robert G. Tardiff and published by . This book was released on 1994-08-16 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrates data obtained from a variety of disciplines to evaluate the current state of knowledge regarding defense mechanisms and applies this information to estimate health risks to humans exposed to substances that alter genetic material. Recognized experts document, to a large extent, which carcinogens can cause injury to human beings and their surroundings, providing guidance for the structured acquisition of key information to reduce cancer risks throughout the environment.
Download or read book Proteases in Health and Disease written by Sajal Chakraborti and published by Springer Science & Business Media. This book was released on 2013-12-04 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area. In-depth critical state-of-the-art reviews will be written by established investigators on proteases dysfunctions associated with pathogenesis of different diseases that are known to occur due to deregulation of proteolytic systems. Multidisciplinary approaches demonstrating biochemical and signal transduction mechanisms associated with deregulation of proteases leading to manifestation of the diseases will be discussed. The book highlights the roles of both intracellular and extracellular proteases in health and disease.
Download or read book Toxoplasmosis of Animals and Humans written by J. P. Dubey and published by CRC Press. This book was released on 2016-04-19 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Found worldwide from Alaska to Australasia, Toxoplasma gondii knows no geographic boundaries. The protozoan is the source of one of the most common parasitic infections in humans, livestock, companion animals, and wildlife, and has gained notoriety with its inclusion on the list of potential bioterrorism microbes. In the two decades since the publi
Download or read book Toxoplasmosis of Animals and Humans Second Edition written by J. P. Dubey and published by CRC Press. This book was released on 1988-08-31 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complete information on T. gondii infections in animals and man is summarized and analyzed in this thorough reference text. Critical in-formation on its economic impact and its effect on production of animals whose flesh is used for food is featured. The clinical and subclinical infections in all major species of livestock are pre-sented. For each animal species, worldwide serological prevalences are tabulated with T. gondii antibody titers, followed by an experi-mental section. Worldwide prevalences of T. gondii infections in mankind is summarized, highlighting epidemiology, symptom diag-nosis, treatment, and prevention. Past research is summarized and areas of future investigations are suggested. This book is highly useful to veterinarians, physicians, biologists, and researchers.
Download or read book The Hologenome Concept Human Animal and Plant Microbiota written by Eugene Rosenberg and published by Springer Science & Business Media. This book was released on 2014-01-31 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Groundbreaking research over the last 10 years has given rise to the hologenome concept of evolution. This concept posits that the holobiont (host plus all of its associated microorganisms) and its hologenome (sum of the genetic information of the host and its symbiotic microorganisms), acting in concert, function as a unique biological entity and therefore as a level of selection in evolution. All animals and plants harbor abundant and diverse microbiota, including viruses. Often the amount of symbiotic microorganisms and their combined genetic information far exceed that of their host. The microbiota with its microbiome, together with the host genome, can be transmitted from one generation to the next and thus propagate the unique properties of the holobiont. The microbial symbionts and the host interact in a cooperative way that affects the health of the holobiont within its environment. Beneficial microbiota protects against pathogens, provides essential nutrients, catabolizes complex polysaccharides, renders harmful chemicals inert, and contributes to the performance of the immune system. In humans and animals, the microbiota also plays a role in behavior. The sum of these cooperative interactions characterizes the holobiont as a unique biological entity. Genetic variation in the hologenome can be brought about by changes in either the host genome or the microbial population genomes (microbiome). Evolution by cooperation can occur by amplifying existing microbes, gaining novel microbiota and by acquiring microbial and viral genes. Under environmental stress, the microbiome can change more rapidly and in response to more processes than the host organism alone and thus influences the evolution of the holobiont. Prebiotics, probiotics, synbiotics and phage therapy are discussed as applied aspects of the hologenome concept.
Download or read book Toxoplasmosis written by David H. M. Joynson and published by Cambridge University Press. This book was released on 2005-09-08 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative and comprehensive account looks at the reemergence of toxoplasmosis as a significant and potentially fatal infection. A team of acknowledged international experts review the latest diagnostic techniques, and the management of infection in pregnant women, neonates, the eye, transplant and other immunosuppressed patients, including AIDS patients. The contentious issue of the role of screening during pregnancy and in the newborn is covered in depth. The introductory chapters on biology, immunology, and epidemiology of the infection provide essential background to understanding the clinical disease. The full range of treatment strategies are presented in an easily accessible form.
Download or read book Amino Acid Fermentation written by Atsushi Yokota and published by Springer. This book was released on 2017-05-11 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest findings on amino acid fermentation and reviews the 50-year history of their development. The book is divided into four parts, the first of which presents a review of amino acid fermentation, past and present. The second part highlights selected examples of amino acid fermentation in more detail, while the third focuses on recent advanced technologies. The last part introduces readers to several topics for future research directions in amino acid production systems. A new field, “amino acid fermentation”, was created by the progress of academic research and industrial development. In 1908, the Japanese researcher Kikunae Ikeda discovered glutamate as an Umami substance. Then a new seasoning, MSG (monosodium glutamate), was commercialized. Although glutamate was extracted from the hydro-lysate of wheat or soybean in the early days, a new production method was subsequently invented – “fermentation” – in which glutamate is produced from sugars such as glucose by a certain bacterium called Corynebacterium. The topic of this volume is particularly connected in a significant way with biochemical, biotechnological, and microbial fields. Both professionals in industry and an academic audience will understand the importance of this volume.
Download or read book Microbial Bioprospecting for Sustainable Development written by Joginder Singh and published by Springer. This book was released on 2018-09-18 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive overview of the use of microorganisms and microbial metabolites as a future sustainable basis of agricultural, environmental and industrial developments. It provides a holistic approach to the latest advances in the utilization of various microorganism bioprospecting including their wide range of applications, traditional uses, modern practices, and designing strategies to harness their potential. In addition, it highlights advanced microbial bioremediation approaches, including genetic manipulation, metagenomics analysis and bacteriophage-based sensors for the detection of food-borne pathogens. Lastly, it elaborates on the latest advances regarding the role of microbes in the sustainable development of various industrial products.
Download or read book Microbial Systematics written by Bhagwan Rekadwad and published by CRC Press. This book was released on 2020-11-01 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent scientific investigations in microbial ecology and systematics. Advanced microbial science investigations employ the latest technologies for research in microbiology and microbial applications. The book has complete information on classical microbiology techniques for assessment of the composition of microbial diversity assessment, advancement in next-generation technology, advantages of microbial products in sustainable developments and their application for societal benefits. Current research on microorganisms is presented as a perfect book for studies on "Microbial Systematics". This book will serve as an important resource for practising research and review for the scientific community.
