Download or read book New Directions in Understanding Dementia and Alzheimer s Disease written by Taher Zandi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: The management of Alzheimer's Disease and the related dementias is one of the major challenges to health care professionals and American society-at-large for the coming decade and the coming millennium. The rapid growth of the over-eighty-five population, the group which, as recent studies have confirmed and as many of us clinicians have long suspected, has an even higher prevalence than previously quoted of dementing disorders, is the major cause of this. We are thus challenged by, as Bernard Issacs used to call it, "the survival of the unfittest," as well as the oPtimistic approach of "bringing life to years," as John F. Kennedy said. The fact is that we, as a society, tend to confuse "treatment" and "cure" (and "prevention"). As the proceedings of the conference which this book represents emphasize, there is considerable work going on about the potential prevention of, or at least the reduction of, symptomatology in these illnesses by interventions genetically, chemIcally, and so forth. However, the more we find out, the more complicated it becomes, and the more heterogeneous Alzheimer's and the related disorders appear to be, not only in their manifestations (as clinicians have long recognized) but also in the individual initiating and underlying processes. For these reasons, absolute preventive techniques or the likelihood of an intervention which will reverse the process in a high proportion of patients, do not appear to be just around the corner.
Download or read book New Directions in Understanding Dementia and Alzheimer s Disease written by Taher Zandi and published by . This book was released on 1991-01-31 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book American Dementia written by Daniel R. George and published by JHU Press. This book was released on 2021-09-14 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The authors argue for a strong connection between public health and social policies that have boosted access to education; quality health care; cleaner air, soil, and water; and a reduction in Alzheimer's disease and dementia. They question the assumption of many that developing a pharmaceutical cure is the best hope for addressing Alzheimer's"--
Download or read book How Not to Study a Disease written by Karl Herrup and published by MIT Press. This book was released on 2023-03-07 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authority on Alzheimer's disease offers a history of past failures and a roadmap that points us in a new direction in our journey to a cure. For decades, some of our best and brightest medical scientists have dedicated themselves to finding a cure for Alzheimer's disease. What happened? Where is the cure? The biggest breakthroughs occurred twenty-five years ago, with little progress since. In How Not to Study a Disease, neurobiologist Karl Herrup explains why the Alzheimer's discoveries of the 1990s didn't bear fruit and maps a direction for future research. Herrup describes the research, explains what's taking so long, and offers an approach for resetting future research. Herrup offers a unique insider's perspective, describing the red flags that science ignored in the rush to find a cure. He is unsparing in calling out the stubbornness, greed, and bad advice that has hamstrung the field, but his final message is a largely optimistic one. Herrup presents a new and sweeping vision of the field that includes a redefinition of the disease and a fresh conceptualization of aging and dementia that asks us to imagine the brain as a series of interconnected "neighborhoods." He calls for changes in virtually every aspect of the Alzheimer's disease research effort, from the drug development process, to the mechanisms of support for basic research, to the often-overlooked role of the scientific media, and more. With How Not to Study a Disease, Herrup provides a roadmap that points us in a new direction in our journey to a cure for Alzheimer's.
Download or read book Understand Alzheimer s written by Calistoga Press and published by Sourcebooks, Inc.. This book was released on 2013-12-23 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: A diagnosis of Alzheimer's disease can be frightening and overwhelming-and not just for the patient. Becoming the primary caregiver for a newly diagnosed loved one can be one of the most challenging-and one of the most rewarding-experiences possible. In Understand Alzheimer's: A First-Time Caregiver's Plan to Understand & Prepare for Alzheimer's & Dementia, you'll find a wealth of practical and useful information to help you and your loved one deal with a diagnosis of Alzheimer's disease. Understand Alzheimer's is a guide to providing compassionate care for a spouse, parent, sibling, or friend, from the early stages of Alzheimer's disease until the end of life. Understand Alzheimer's is a comprehensive and thoughtful guide to caring for a loved one with Alzheimer's, with: An in-depth explanation of the seven stages of Alzheimer's disease and what the diagnosis means Checklists for how to prepare your loved one's surroundings for safety and ease of activities Compassionate advice for managing your stress and finding the balance to keep you from feeling depressed, lonely, and isolated A list of resources with information for supporting those with Alzheimer's disease, and organizations that can help build a caregiving network A guide to Alzheimer's treatment options and a checklist for dealing with medical professionals Helpful suggestions for managing the changes in your loved one's behavior Living with Alzheimer's disease presents daily challenges for both the caregiver and patient. Understand Alzheimer's is a practical guide that helps you and your loved one cope with Alzheimer's while maintaining the best quality of life possible for both of you.
Download or read book Understanding Alzheimer s Disease written by Neal R. Cutler and published by Univ. Press of Mississippi. This book was released on 2010-02-11 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease has received growing attention in recent years because the affected population is growing quickly as life spans in America creep ever upward. As they near retirement, many Americans start to fear that any minor memory lapse-misplacing the keys or forgetting a name-might spell Alzheimer's. In reality such incidents are a normal part of the aging process. In Alzheimer's disease, such incidents progress to a point at which they interfere with normal daily activities on a regular basis, and memory loss becomes progressively more disabling. This book is written for anyone interested in learning more about Alzheimer's disease-people who have it, their families and caregivers, professionals who serve such people, teachers, and anyone with a general interest in the disease. An important feature of this book is clear explanation of the basic biology of the disease. Here is information about who gets the disease, how it is diagnosed, and what happens to people who have it. A large section is devoted to the subject of caring for affected individuals, including legal and financial planning advice and pointers for finding outside support services. Existing treatments are discussed along with suggestions for handling many symptoms without drugs. Understanding Alzheimer's Disease describes the most current knowledge of how and why it arises and gives information about the many avenues being explored in search of a cure. With its chapters on causes and on the search for treatments, this guide will be of interest to a wider section of the population than other books on the disease.
Download or read book The Neurobiology of Aging and Alzheimer Disease in Down Syndrome written by Elizabeth Head and published by Academic Press. This book was released on 2021-08-31 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena. Discusses the complexities involved with aging and Alzheimer’s disease in Down syndrome Summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age Serves as learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research
Download or read book 2015 Which new directions for Alzheimer s disease written by Ludovic Martin and published by Frontiers Media SA. This book was released on 2015-06-03 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the World Health Organization, more than 40 million people in the world are affected with dementia. To date, 60-70% of the cases of dementia are attributed to the Alzheimer's disease (AD). This neurodegenerative disorder gradually takes place over a period of at least 20 years before the onset of symptoms, which are impaired memory, apathy and depression. The characteristics of AD consist in neurofibrillary tangles (intraneuronal aggregates of hyperphosphorylated tau proteins) and senile plaques (dense extraneuronal deposits composed of amyloid ß (Aß)). The other features linked to these two core pathological hallmarks of AD are inflammation, oxidative stress, progressive synaptic and neuronal loss. In past years, some of the emerging therapeutic strategies against AD were employed to deal with the pathological hallmarks of the disease. Science teams all over the world try to restore the tau phosphorylation equilibrium. Their purpose is to interfere with the aggregation of tau and decrease its amount of proteins per se as well. Furthermore, they are trying either to stimulate the elimination processes of the aggregated tau proteins or to stop the formation of Aß peptides. This could be reached by the stimulation of the classic techniques of protein degradation such as the autophagic pathway, or by the targeted immunotherapy. In this Research Topic, we wish to summarize and review the etiology of AD and the related therapeutic opportunities for the next decades. To fully understand the precise mechanisms underlying AD, research findings, reviews, new insights and new approaches include AD and related tauopathies, tau phosphorylation balance, pharmacological compounds against AD, neuroprotection strategies and new therapeutic ways but also risk factors for AD and AD genetic information are included in this issue.
Download or read book Dementia written by Susan Hunter and published by Jessica Kingsley Publishers. This book was released on 1997-01-01 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a focus for academic and professional study, dementia has moved rapidly from the margin to the mainstream during the last decade. Understanding of this distressing condition, its aetiology and recognition, has become much more widespread and sophisticated. Building on such clinical knowledge, this book challenges the reader - to think ethically and in a person-centred way about the implications of dementia at a personal, planning and service provision level - to consider consumer perspectives, not only those of carers but also the much neglected views of individuals with dementia - to explore less well documented areas such as dementia and Down's Syndrome, depression and early onset dementia. In conclusion, the book illuminates selected topical developments in service provision such as community care, advocacy and aspects of the built and social care environment.
Download or read book Alzheimer s Disease Decoded written by Sahyouni Ronald and published by World Scientific. This book was released on 2016-10-06 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book aims to present, educate and inform individuals about Alzheimer's disease in a comprehensive manner. Its scope ranges from the discovery of the disease, epidemiology and basic biological principles underlying it, to advanced stem cell therapies used in the treatment of Alzheimer's. It adopts a 'global' perspective on Alzheimer's disease, and include epidemiological data and science from countries around the world. Alzheimer's disease is a rapidly growing problem seen in every country around the world. This is the first and only comprehensive book to cover Alzheimer's disease, and includes the most updated literature and scientific progress in the field of dementia and Alzheimer's disease research. Most books on the market that focus on Alzheimer's disease are targeted at caregivers as practical advice on how to deal with loved ones with the disease. This book instead is a comprehensive and popular science book that can be read by anyone with an interest in learning more about the disease. Dr. Jefferson Chen MD, PhD, co-author, participated in the world's first surgical clinical trial using shunts to treat Alzheimer's disease. His first-hand involvement in a clinical trial for patients with Alzheimer's disease and experience treating Normal Pressure Hydrocephalus (NPH) which is commonly misdiagnosed as Alzheimer's disease lends a unique perspective. This book with appeal to a wide audience, regardless of their scientific or educational background.
Download or read book Understanding Alzheimer s Disease written by Miriam K. Aronson and published by Diane Books Publishing Company. This book was released on 1998-09-01 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: An in-depth, comprehensive guide to a devastating disease that affects over 3 mill. Amer. Pt. I covers diagnosis, possible causes, and treatment strategies. Pt. II focuses on coping with Alzheimer1s disease (AD), with attention to the needs of the family and friends of Alzheimer patients. Discusses: dealing with the emotional turmoil of the disease; helping younger family members cope with the illness of a loved one; joining a support group; services for patients and families; and how and when to place a loved one in a nursing home. Pt. III discusses the legal and financial aspects of AD, including how to do legal planning, and the rights of and duties to the terminally ill.
Download or read book Future Directions for the Demography of Aging written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-07-21 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost 25 years have passed since the Demography of Aging (1994) was published by the National Research Council. Future Directions for the Demography of Aging is, in many ways, the successor to that original volume. The Division of Behavioral and Social Research at the National Institute on Aging (NIA) asked the National Academies of Sciences, Engineering, and Medicine to produce an authoritative guide to new directions in demography of aging. The papers published in this report were originally presented and discussed at a public workshop held in Washington, D.C., August 17-18, 2017. The workshop discussion made evident that major new advances had been made in the last two decades, but also that new trends and research directions have emerged that call for innovative conceptual, design, and measurement approaches. The report reviews these recent trends and also discusses future directions for research on a range of topics that are central to current research in the demography of aging. Looking back over the past two decades of demography of aging research shows remarkable advances in our understanding of the health and well-being of the older population. Equally exciting is that this report sets the stage for the next two decades of innovative researchâ€"a period of rapid growth in the older American population.
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1991 with total page 968 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Directions in Aging Research written by Ruby R. Brougham and published by Nova Science Publishers. This book was released on 2009 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the greatest challenges of the 21st century is global ageing. A primary objective of this book is to review research that is at the forefront in providing information regarding the decline, maintenance, and improvements in health and cognition that are associated with age. Another objective is to provide information regarding pioneering methods to ameliorate age-related declines. It brings together scholars with a wide variety of expertise who present innovative ideas about lifestyle and brain health, quality of life issues, memory interventions, methodology for pain assessment, health communication, decision-making, future time perspective, and retirement goals. The reader will finish this book with a greater understanding of the problems and potential solutions for addressing the important problems of an ageing population. This timely book will make an important contribution to the current aging literature by offering new ideas to stimulate further research and application in understanding health, cognition, and ageing. This book is appropriate for advanced undergraduate students, graduate students, and professionals who study or work in the fields of psychology, gerontology, social work, human development and health fields such as nursing, physical therapy, and occupational therapy.
Download or read book New Directions in Geriatric Medicine written by Lee Ann Lindquist and published by Springer. This book was released on 2016-04-09 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to present the clinical geriatric trends within general internal medicine and family practice, which practitioners often encounter in caring for their older adult patients. Chapters focus on increasingly difficult clinical decisions that practitioners have to make in caring for older adults, who often experience medical complications due to memory loss, physical disability, and multiple chronic conditions. Written by experts in geriatric medicine, each of these chapters start with the most up-to-date clinical geriatric research and provide specific examples or case studies on how to use this information to address the clinical needs of older adult patients. In addition, there is a set of concise “take-home points” for each chapter that are easy to commit to memory and implement in clinical care of aging patients. As the only book to focus on current trends in geriatric research and evidence-based eldercare practice, Clinical Trends in Geriatric Medicine is of great value to internists, family practitioners, geriatricians, nurses, and physician assistants who care for older adults.
Download or read book Reducing the Impact of Dementia in America written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2022-04-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.
Download or read book Alzheimer s Disease Decoded written by Ronald Sahyouni and published by . This book was released on 2016 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
