Download or read book New Concepts in Alzheimer s Disease written by M. Briley and published by . This book was released on 1986 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Concepts of Alzheimer Disease written by Peter J. Whitehouse and published by JHU Press. This book was released on 2003-05-27 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the essays in this volume show, conceptualizing dementia has always been a complex process. With contributions from noted professionals in psychiatry, neurology, molecular biology, sociology, history, ethics, and health policy, Concepts of Alzheimer Disease looks at the ways in which Alzheimer disease has been defined in various historical and cultural contexts. The book covers every major development in the field, from the first case described by Alois Alzheimer in 1907 through groundbreaking work on the genetics of the disease. Essays examine not only the prominent role that biomedical and clinical researchers have played in defining Alzheimer disease, but also the ways in which the perspectives of patients, their caregivers, and the broader public have shaped concepts.
Download or read book New Trends in the Diagnosis and Therapy of Alzheimer s Disease written by Kurt A. Jellinger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer ́s Disease (AD), the most frequent cause of mental decline in the elderly represents one of the major health problems facing modern society. Despite considerable progress in the clinical diagnosis, epidemiology, structural basis, biochemistry, molecular genetics, and pharmacological aspects of AD, its etiology, molecular backgrounds, and treatment challenges are still poorly understood. This volume based on the 2nd International Symposium of EBEWE Research Initiative in October 1993 in Salzburg, Austria, is conceived as a review of our current knowledge of morphology, diagnostic clinical and imaging techniques, methodological approaches of cognitive assessment, trial designs, outcome variables and possibilities of therapy of AD and other neurodegenerative disorders. The book ́s coverage is broad and it should be of interest for investigators, clinicians, and researchers involved in the problems of AD.
Download or read book Alzheimer s Disease Modernizing Concept Biological Diagnosis and Therapy written by M.C. Carrillo and published by Karger Medical and Scientific Publishers. This book was released on 2012-04-23 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding knowledge on genetic and epigenetic risk factors is rapidly enhancing our understanding of the complex molecular interactions and systems involved in the pathogenesis of Alzheimer’s disease. In this publication, leading experts discuss emerging novel conceptual models of the disease along with advances in the development of surrogate markers that will not only improve the accuracy of diagnostic technologies but also improve the prospects of developing disease-modifying interventions. The novel framework of the disease presented here highlights research on biological markers as well as efforts to validate technologies for early and accurate detection. It also introduces notion of a complex systems dysfunction that extends beyond prevailing ideas derived from the ‘amyloid’ or ‘tau’ hypotheses.This outstanding publication provides researchers, clinicians, students and other professionals interested in neurodegenerative disorders with a comprehensive update on current trends and future directions in therapy development, with special focus on advances in clinical trial designs.
Download or read book Alzheimer s Turning Point written by Jack C. de la Torre and published by Springer. This book was released on 2016-06-25 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compelling text provides an overview of the available technology for early detection and therapeutic management of vascular risk factors to Alzheimer’s before severe cognitive impairment symptoms appear. Chapters bring the reader from the trackless clinical research that has characterized Alzheimer’s progress for the last 20 years, to a nexus of new ideas and concepts that can change our outlook of this dementia. In-depth examinations of various hypotheses, preventive measures, current and prospective treatments are openly and clearly explored. The author discusses in depth his proposal of the vascular hypothesis of Alzheimer's disease which has become a mother-lode for basic and clinical studies and a key approach to the prevention of this dementia.Alzheimer’s Turning Point offers professionals, students and those looking to learn more about this disorder a fresh clinical perspective of this devastating disease.
Download or read book Alzheimer s Disease written by Robert J. Dillmann and published by . This book was released on 1990 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Neurobiology of Aging and Alzheimer Disease in Down Syndrome written by Elizabeth Head and published by Academic Press. This book was released on 2021-08-31 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena. Discusses the complexities involved with aging and Alzheimer’s disease in Down syndrome Summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age Serves as learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research
Download or read book High and Rising Mortality Rates Among Working Age Adults written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-12-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alzheimer s Disease Drug Development written by Jeffrey Cummings and published by Cambridge University Press. This book was released on 2022-03-31 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Download or read book New Trends in the Diagnosis and Therapy of Non Alzheimer s Dementia written by Kurt A. Jellinger and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume gives an overview of the present state of art on the classification, neuropathology, clinical presentation, neuropsychology, diagnosis, neuroimaging and therapeutic possibilities in non-Alzheimer’s dementias, an increasingly important group of CNS diseases, which account for 7 to 30% of dementing disorders in adults and aged subjects, and thus, represent the second most frequent cause of dementia after Alzheimer’s disease. The monograph provides the newest information for neurologists, psychiatrists, dementia research workers, dementia clinicians, neuropathologists, neurobiologists, and practicing physicians.
Download or read book The Alzheimer Conundrum written by Margaret Lock and published by Princeton University Press. This book was released on 2015-10-20 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why our approaches to Alzheimer's and dementia are problematic and contradictory Due to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no effective treatment has been discovered for Alzheimer's disease, the most common form of dementia. The Alzheimer Conundrum exposes the predicaments embedded in current efforts to slow down or halt Alzheimer’s disease through early detection of pre-symptomatic biological changes in healthy individuals. Based on a meticulous account of the history of Alzheimer’s disease and extensive in-depth interviews, Margaret Lock highlights the limitations and the dissent associated with biomarker detection. Lock argues that basic research must continue, but should be complemented by a public health approach to prevention that is economically feasible, more humane, and much more effective globally than one exclusively focused on an increasingly harried search for a cure.
Download or read book Alzheimer s In America written by Maria Shriver and published by Free Press. This book was released on 2011-04-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Shriver Report: A Woman’s Nation Takes on Alzheimer’s will be the first comprehensive multi-disciplinary look at these questions at this transformational moment. The Report will digest the current trends in thinking about Alzheimer’s, examine cutting-edge medical research, look at societal impacts, and include a groundbreaking and comprehensive national poll. It will feature original photography and personal essays by men and women – some from the public arena with names you know, some from everyday America – sharing their personal struggles with the disease as patients, caregivers and family members.
Download or read book Emerging Technologies for Diagnosing Alzheimer s Disease written by Marianne Boenink and published by Springer. This book was released on 2016-09-13 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores international biomedical research and development on the early diagnosis of Alzheimer's disease. It offers timely, multidisciplinary reflections on the social and ethical issues raised by promises of early diagnostics and asks under which conditions emerging diagnostic technologies can be considered a responsible innovation. The initial chapters in this edited volume provide an overview and a critical discussion of recent developments in biomedical research on Alzheimer's disease. Subsequent contributions explore the values at stake in current practices of dealing with Alzheimer's disease and dementia, both within and outside the biomedical domain. Novel diagnostic technologies for Alzheimer's disease emerge in a complex and shifting field, full of controversies. Innovating with care requires a precise mapping of how concepts, values and responsibilities are filled in through the confrontation of practices. In doing so, the volume offers a practice-based approach of responsible innovation that is also applicable to other fields of innovation.
Download or read book How Not to Study a Disease written by Karl Herrup and published by MIT Press. This book was released on 2023-03-07 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authority on Alzheimer's disease offers a history of past failures and a roadmap that points us in a new direction in our journey to a cure. For decades, some of our best and brightest medical scientists have dedicated themselves to finding a cure for Alzheimer's disease. What happened? Where is the cure? The biggest breakthroughs occurred twenty-five years ago, with little progress since. In How Not to Study a Disease, neurobiologist Karl Herrup explains why the Alzheimer's discoveries of the 1990s didn't bear fruit and maps a direction for future research. Herrup describes the research, explains what's taking so long, and offers an approach for resetting future research. Herrup offers a unique insider's perspective, describing the red flags that science ignored in the rush to find a cure. He is unsparing in calling out the stubbornness, greed, and bad advice that has hamstrung the field, but his final message is a largely optimistic one. Herrup presents a new and sweeping vision of the field that includes a redefinition of the disease and a fresh conceptualization of aging and dementia that asks us to imagine the brain as a series of interconnected "neighborhoods." He calls for changes in virtually every aspect of the Alzheimer's disease research effort, from the drug development process, to the mechanisms of support for basic research, to the often-overlooked role of the scientific media, and more. With How Not to Study a Disease, Herrup provides a roadmap that points us in a new direction in our journey to a cure for Alzheimer's.
Download or read book Neurology in Clinical Practice written by Walter George Bradley and published by . This book was released on 2004 with total page 1672 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.
Download or read book I m Still Here written by John Zeisel and published by Penguin. This book was released on 2009 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses ways to mentally connect with a person who has been diagnosed with Alzheimer's disease, which includes engaging individuals through the healthier parts of the brain.
Download or read book The Neurobiology of Alzheimer s Disease written by Study Group on the Pharmacology of Memory Disorders Associated with Aging. Meeting and published by . This book was released on 1996 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: The overall goal of the International Study Group on the Pharmacology of Memory Disorders Associated with Ageing is to point out discoveries that shed light on the potential causes of Alzheimer's disease, its pathogenesis, and the biological mechanisms that could underlie its cure. This eighth meeting in the series, aims to stimulate research in dementia and increase the transfer of information from the basic sciences to physicians and the pharmaceutical industry."
