Download or read book Neutron Capture Therapy written by Wolfgang A.G. Sauerwein and published by Springer Science & Business Media. This book was released on 2012-11-05 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probability and immediately to release heavy particles with a path length of one cell diameter, which in principle allows for tumor cell-selective high-LET particle radiotherapy. This book provides a comprehensive summary of the progress made in NCT in recent years. Individual sections cover all important aspects, including neutron sources, boron chemistry, drugs for NCT, dosimetry, and radiation biology. The use of NCT in a variety of malignancies and also some non-malignant diseases is extensively discussed. NCT is clearly shown to be a promising modality at the threshold of wider clinical application. All of the chapters are written by experienced specialists in language that will be readily understood by all participating disciplines.
Download or read book Advances in Neutron Capture Therapy written by A.H. Soloway and published by Springer Science & Business Media. This book was released on 1993 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: Binary systems for the treatment of cancer potentially are among the most attractive of the new therapeutic modalities that currently are under investigation. The basicconcept is to selectivelydestroy malignantcells whileconcomitantlysparing normal tissue. Neutron capture therapy (NCT) is the binary system that has been the subject of the Fifth International Symposium on Neutron Capture Therapy, which was held September13-17, 1992, in Columbus, Ohio, undertheauspicesoftheInternational Society for Neutron Capture Therapy. Its objective was to bring together researchers from throughout the world and to provide a forum at which they could present the latest advances in the development of Neutron capture therapy. Neutron capture therapy has largely, but not exclusively, focused on the use of boron-10 as the target nuclide. Boron neutron capture therapy (BNCT) is based on the nuclear reaction that occurs when the stable isotope, boron-10, absorbs low-energy non ionizing thermal neutrons to yield alphaparticles and recoiling lithium-7 nuclei. The size and energy of these high linear energy transfer (LET) particles result in their being confined largely to the cells in which the capture reaction occurs. For BNCT to be successful, a sufficient numberof I~atoms mustbe localized within neoplastic cells, and enough thermal neutrons must be delivered and absorbed by the I~ to produce a lethal 1~(n,QVLi reaction. Two major problems must be surmounted.
Download or read book Intense Neutron Sources written by U.S. Atomic Energy Commission and published by . This book was released on 1966 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Applications of Research Reactors written by International Atomic Energy Agency and published by International Atomic Energy Agency. This book was released on 2014 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is a comprehensive study that reviews the current situation in a great number of applications of research reactors. It revises the contents of IAEA TECDOC-1234, The Applications of Research Reactors, giving detailed updates on each field of research reactor uses worldwide. Reactors of all sizes and capabilities can benefit from the sharing of current practices and research enabled via this updated version, which describes the requirements for practicing methods as diverse as neutron activation analysis, education and training, neutron scattering and neutron imaging, silicon doping and radioisotope production, material/fuel irradiation and testing, and some others. Many underutilised research reactors can learn how to diversify their technical capabilities, staff and potential commercial partners and users seeking research reactor services and products. The content of the publication has also been strengthened in terms of current issues facing the vast majority of research reactors by including sections describing user and customer relations as well as strategic planning considerations.
Download or read book Frontiers in Neutron Capture Therapy written by M. Frederick Hawthorne and published by Springer. This book was released on 2013-11-11 with total page 1389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Neutron Capture Therapy contains current research results originally presented at the Eighth International Symposium on Neutron Capture Therapy for Cancer in La Jolla, CA. This comprehensive collection of peer-reviewed manuscripts is showcased in two volumes covering all aspects of the development of this multidisciplinary approach to cancer therapy. Volume I of this work includes clinical results and current progress in treatment planning, neutron sources and dosimetry, while Volume II presents the synthesis, pharmacology and tissue-targeting design of boron compounds, including work on preclinical dosimetry and radiobiology. Intended for researchers and clinicians involved with or interested in new modes of cancer therapy, this volume will also serve as a useful guideline for scientists, students, and practitioners in the field.
Download or read book Proceedings of International Conference on Nuclear Data for Science and Technology written by and published by . This book was released on 2002 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book History Development and Future of TRIGA Research Reactors written by and published by . This book was released on 2016 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Analysis of Cancer Risks in Populations Near Nuclear Facilities written by National Research Council and published by National Academies Press. This book was released on 2012-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.
Download or read book Proceedings of the 1998 ANS Radiation Protection and Shielding Division Topical Conference written by and published by . This book was released on 1998 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Photoneutron Sources written by B. W. Sargent and published by . This book was released on 1946 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cancer Neutron Capture Therapy written by Y. Mishima and published by Springer. This book was released on 2013-05-17 with total page 920 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are many human cancers which actively synthesize specific characteristic proteins such as melanomas, thyroid cancer and squamous cell carcinoma. Many cancer researchers have of course tried to utilize this specific activity as a key for the selective treatment of cancers. In the past for example, the molecular hybrid compound of DOPA, a substrate of melanin, and nitrogen mustard N-oxide hydrochloride, a ctyotoxic anti-tumor drug, was synthesized as Melphalan and used to treat malignant melanoma. A major problem arose though in that it was soon found to be highly suppressive toward bone marrow and quite toxic while not being remarkably effective. Thus, malignant melanoma could not be cured by it. Such failure led us to develop a novel bimodal therapeutic system which includes the use of non-toxic potentially cytocidal chemicals which selectively accumulate within the cancer cells and which are converted by a controllable modality into an actively cytocidal element in situ. We can now non-surgically cure malignant melanoma and glioblastoma with our selective cancer treatment, neutron capture therapy (NCT); as can be found in this volume. Included are 124 papers on the latest breaking developments discussed at the Sixth International Symposium on NCT for Cancer held in Kobe during the late autumn of 1994.
Download or read book Handbook of Brain Tumor Chemotherapy written by Herbert B. Newton and published by Elsevier. This book was released on 2005-12-19 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment of patients with a brain tumor remains one of the most challenging and difficult areas of modern oncology. Recent advances in the molecular biology of these neoplasms have improved our understanding of the malignant phenotype and have lead to the development of novel forms of chemotherapy, including "targeted agents. The Handbook of Brain Tumor Chemotherapy reviews the state-of-the-art of chemotherapy development and clinical treatment of patients with this devastating disease. Handbook of Brain Tumor Chemotherapy offers a unique cutting-edge compendium of basic science and clinical information on the subject of brain tumor chemotherapy, reviewing what has been accomplished thus far and how the field will continue to evolve with the development of more specific and efficacious chemotherapeutic agents. This book represents the most complete single-volume resource available for information on the subject of brain tumor chemotherapy. - Provides the most up to date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics, for the treatment of brain tumors - Broadly appeals to anyone interested in the field of Neuro-Oncology and in the treatment of patients with brain tumors - Useful to clinicians interested in a thorough overview of the use of chemotherapy in patients with a broad range of brain tumors as well as serving as a source of background information to basic scientists and pharmaceutical researchers with an interest in the molecular therapeutics of brain tumors
Download or read book Status of Accelerator Driven Systems Research and Technology Development written by International Atomic Energy Agency and published by IAEA Tecdoc. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the greatest challenges for nuclear energy is how to properly manage the highly radioactive waste generated during irradiation in nuclear reactors. Accelerator Driven Systems (ADSs) may offer new prospects and advantages for the transmutation of such high level nuclear waste. ADS or accelerator driven transmutation of waste (ATW) consists of a high power proton accelerator, a heavy metal spallation target that produces neutrons when bombarded by the high power beam, and a sub-critical core that is neutronically coupled to the spallation target. This publication provides a comprehensive state of the art of the ADS technology by representing the different ADS concepts proposed worldwide in the last 15 years, as well as the related R&D activities and demonstration initiatives carried out at national international level.
Download or read book Chemical Abstracts written by and published by . This book was released on 1990 with total page 2598 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fusion Technology 1990 written by B.E. Keen and published by Elsevier. This book was released on 2012-12-02 with total page 1039 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the biennial series of symposia on Fusion Technology, organized by the European Fusion Laboratories, is the exchange of information on the design, construction and operation of fusion experiments. The coverage of the volume includes the technology aspects of fusion reactors to provide a link to the technology of new developments and form a guideline for the definition of future work. These proceedings comprise two volumes and contain both the invited lectures and contributed papers presented at the Symposium, which was attended by 556 participants from around the globe. The 312 papers in this volume, including 17 invited papers, give a broad and current overview of the progress and trends fusion technology is experiencing now, and the future for fusion devices.
Download or read book Nuclear Technology written by and published by . This book was released on 1988 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nuclear Regulatory Commission Issuances written by U.S. Nuclear Regulatory Commission and published by . This book was released on 1979 with total page 950 pages. Available in PDF, EPUB and Kindle. Book excerpt:
