Download or read book Neuronal cell signaling and behavior written by Riccardo Brambilla and published by Frontiers E-books. This book was released on with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learning and memory functions as well as many neurodegenerative and neuropsychiatric disorders, including Parkinson’s disease, drug addiction and schizophrenia are caused by dysregulation of cell signaling mechanisms in the brain. This issue of Frontiers will provide evidence for signal transduction alterations implicated in cognitive and non cognitive behaviors, as investigated by means of pharmacological and genetic approaches. Specialists in the field will be invited to contribute articles covering the impact on behavior of manipulations of neurotransmitter systems, intracellular signaling cascades and gene expression.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neuron Signaling in Metabolic Regulation written by Qingchun Tong and published by CRC Press. This book was released on 2021-06-07 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on neuron signaling in the regulation of metabolism and body weight, and especially on methods used in these studies. Obesity and related metabolic syndromes have reached epidemic status, but still are no effective strategies for prevention and treatment. Body weight homeostasis is maintained by balanced food intake and energy expenditure, both of which are under the control of brain neurons. In the recent years, significant progress has been made in identifying specific neurons, neural pathways, and non-neuron cells in feeding regulation, as well as in delineating autonomic nervous systems targeting peripheral metabolic tissues in the regulation of energy expenditure and metabolism. This book reviews recent progress on important neuron signaling for body weight and metabolic regulation and the state-of-the-art methods that has been applied in this field, ranging from animal models with neuron-specific manipulations, pharmacology, optogenetics, in vivo Ca2+ imaging, and viral tracing. Readers will be exposed to latest research frontiers on neuron regulation of metabolism. Key Features Explores the role signaling between neurons plays with respect to metabolism Documents how neurotransmitters affect the regulation of feeding Describes various methods and technologies used to study the neuronal control of metabolism Includes contributions from an international team of leading researchers. Related Titles Lim, W. & B. Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1) Feltz, A. Physiology of Neurons (ISBN 978-0-8153-4600-5) Zempleni, J. & K. Dakshinamurti, eds. Nutrients and Cell Signaling (ISBN 978-0367-39307-6)
Download or read book Neural Cell Behavior and Fuzzy Logic written by Uziel Sandler and published by Springer Science & Business Media. This book was released on 2008-09-23 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers at an advanced level the most fundamental ideas, concepts and methods in the field of applications of fuzzy logic to the study of neural cell behavior. Motivation and awareness are examined from a physiological and biochemical perspective illustrating fuzzy mechanisms of complex systems.
Download or read book Glial Cells written by Peter R. Laming and published by Cambridge University Press. This book was released on 1998-06-28 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 1998 book discusses how neurons and glial cells interact with each other to influence behaviour.
Download or read book Neural Surface Antigens written by Jan Pruszak and published by Academic Press. This book was released on 2015-03-23 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural Surface Antigens: From Basic Biology towards Biomedical Applications focuses on the functionalrole of surface molecules in neural development, stem cell research, and translational biomedical paradigms.With an emphasis on human and rodent model systems, this reference covers fundamentals of neural stemcell biology and flow cytometric methodology. Addressing cell biologists as well as clinicians working in theneurosciences, the book was conceived by an international panel of experts to cover a vast array of particularsurface antigen families and subtypes. It provides insight into the basic biology and functional mechanisms ofneural cell surface signaling molecules influencing mammalian development, regeneration, and treatments. - Introduces early phase clinical trials of neural stem cells - Outlines characterization of surface molecule expression and methods for isolation which open unprecedented opportunities for functional study, quantitation & diagnostics - Highlights the role of stem cells in neural surface antigen and biomarker analysis and applications
Download or read book Pituitary Adenylate Cyclase Activating Polypeptide written by Hubert Vaudry and published by Springer Science & Business Media. This book was released on 2003 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.
Download or read book Cell Signaling and Neural Circuits in Chronic Diseases of the Central Nervous System written by Francesco Ferraguti and published by Frontiers Media SA. This book was released on 2021-12-30 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.
Download or read book The Neuron written by Irwin B. Levitan and published by Oxford University Press, USA. This book was released on 1997 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for use by advanced undergraduate, graduate, and medical students, The Neuron: Cell and Molecular Biology is an intriguing study of the unique biochemical and physiological properties of neurons, which emphasizes the molecular mechanisms that generate and regulate their activity. Keeping abreast of the enormous advances in neuroscience in the five years since the first edition was published, the authors have revised all their chapters in the second edition. What was formerly the first chapter has been expanded substantially and divided into two separate chapters to emphasize the cell biology of neurons and glia, and their commonalities with other kinds of cells. The section on intracellular communication has also been expanded and reorganized. Levitan and Kaczmarek introduce the concept of ion channels as specialized membrane proteins at an early stage, making the idea of selective membrane permeability more accessible in terms of the properties of specific ion channel proteins. In addition, they emphasize the astonishing diversity of voltage-dependent ion channels that has become evident in recent years, and discuss the implications of this diversity for neuronal physiology. In the section on intercellular communication, the chapter on neurotransmitter secretion has also been rewritten to reflect the new level of understanding of secretion that has resulted from the identification of many of the molecular players in vesicle fusion and exocytosis. The other chapters in this section have also been fully revised to incorporate new information resulting from the cloning and characterization of the multitude of glutamate receptors as well as to describe novel elements of intracellular signaling pathways in neurons and other cells. Finally, the last section has been substantially updated to reflect the recent successes of molecular studies of development and plasticity. As more and more of the molecular entities that are essential for neuronal development and adult plasticity are identified and characterized, phenomena that previously could be studied only at the descriptive level can now be explained in greater depth.
Download or read book Mapping the Brain and Its Functions written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant advances in brain research have been made, but investigators who face the resulting explosion of data need new methods to integrate the pieces of the "brain puzzle." Based on the expertise of more than 100 neuroscientists and computer specialists, this new volume examines how computer technology can meet that need. Featuring outstanding color photography, the book presents an overview of the complexity of brain research, which covers the spectrum from human behavior to genetic mechanisms. Advances in vision, substance abuse, pain, and schizophrenia are highlighted. The committee explores the potential benefits of computer graphics, database systems, and communications networks in neuroscience and reviews the available technology. Recommendations center on a proposed Brain Mapping Initiative, with an agenda for implementation and a look at issues such as privacy and accessibility.
Download or read book Governing Behavior written by Ari Berkowitz and published by Harvard University Press. This book was released on 2016-03-14 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: From simple reflexes to complex choreographies of movement, all animal behavior is governed by a nervous system. But what kind of government is it—a dictatorship or a democracy? Nervous systems consist of circuits of interconnected nerve cells (neurons) that transmit and receive information via electrical signals. Every moment, each neuron adds up stimulating and inhibiting inputs from many other neurons to determine whether to send an electrical signal to its recipients. Some circuits are dominated by a single “dictator” neuron that gathers information from many sources and then issues commands, such as the Mauthner neuron that triggers escape in fish. In other more “democratic” circuits, such as those mediating eye movements in monkeys, the outcome is determined by a tally of “votes” from a large population of neurons. Rhythmic movements like breathing and locomotion are generated by “government programs” within the central nervous system, but modified by a soup of chemicals and by free market–like feedback from sensory neurons. Nervous systems also use sophisticated surveillance of the surrounding environment and keep track of their own decisions in order to avoid internal conflicts. Nervous systems are not restricted to using one set of procedures at a time. They have evolved over long periods to control behaviors in whichever ways are most effective, and they essentially combine multiple forms of government simultaneously. Engaging and accessible, Governing Behavior explains the variety of structures and strategies that control behavior, while providing an overview of thought-provoking debates and cutting-edge research in neurobiology.
Download or read book The Neuron written by Irwin B. Levitan and published by Oxford University Press, USA. This book was released on 2002 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.
Download or read book Governing Behavior written by Ari Berkowitz and published by Harvard University Press. This book was released on 2016-03-14 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: From simple reflexes to complex movements, all animal behavior is governed by a nervous system. But what kind of government is it—a dictatorship or a democracy? Ari Berkowitz explains the variety of structures and strategies that control behavior, while providing an overview of thought-provoking debates and cutting-edge research.
Download or read book Neuroethology written by Jeffrey M. Camhi and published by Sinauer Associates, Incorporated. This book was released on 1984 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Roles of Extra synaptic Serotonin Receptors in Neuronal Signaling and Behavior written by Alec W. Gibson and published by . This book was released on 2020 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serotonin signaling is implicated in a variety of psychiatric conditions and regulates behaviors through both synaptic and extra-synaptic neurotransmission. Two serotonin receptors, the 5-HT[subscript]1B and 5-HT6 receptors, are noted for their mediation of extra-synaptic serotonin signaling and unique localization. 5-HT[subscript]1B receptors localize to axon terminals and inhibit the release of neurotransmitters. 5-HT6 receptors localize to neuronal primary cilia where they serve as excitatory receptors and are particularly abundant in the direct and indirect pathway neurons of the striatum. While many aspects of the serotonergic system have been well studied, the ways in which these extra-synaptic serotonin receptors modulate neuronal signaling and circuit-specific behaviors are poorly understood. We first describe the creation of neuronal cell lines with stable expression of 5-HT[subscript]1B receptors and loss of either isoform of [Beta]-arrestin in order to elucidate the intracellular signaling mechanisms of 5-HT1B receptors. We next use these cell lines to show that 5-HT[subscript]1B receptors activate ERK1/2 signaling in a G[alpha][subscript]s- and [Beta]-arrestin-dependent manner. Finally, we demonstrate that 5-HT6 receptors modulate cocaine reinforcement in a pathway-specific manner; specifically, increased 5-HT6 receptor signaling in the indirect pathway of the nucleus accumbens reduces cocaine taking by increasing the reinforcing properties of the drug. Together, these findings increase our understanding of extra-synaptic serotonin receptors and the mechanisms by which they influence intracellular signaling cascades and circuit-specific behaviors.
Download or read book Nerve Cells and Animal Behaviour written by Peter Simmons and published by Cambridge University Press. This book was released on 2010-05-27 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes photographs which capture the detail of the behaviour.
