Download or read book Negative Ion Chemical Ionization GC MS Method Development for Detection of Biogenically Important Polyamines in Human Cadaver Decomposition written by and published by . This book was released on 2018 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt: The search for the chemical signature of death has focused over the past decade on desorption VOC methods of detection. Our group has been working on a method to detect the less easily detected but biogenically important polyamines that are well known to be part of the decomposition process – putrescine and cadaverine. Putrescine (PUT) and cadaverine (CAD) are known for their malodorous properties and may be important components that human remains detection (HRD) canines detect. To date, there are no published studies that have reported detecting these compounds in any of the forensic research of cadaver decomposition. As polyamines are volatile compounds known to readily absorb on polar surfaces, such as silica, they could be retained in soil for an indeterminate time and be an important factor in the chemical signature that is being detected by the HRD canines. The objective of this project was to determine if small biogenic amines can be detected from soil samples. First the amines were separated from soils as conjugate acids, basified, and extracted into a nonaqueous solvent. Fluorinated amide derivatives of PUT, CAD and other test amines were made and subsequently analyzed by negative ion chemical ionization (NICI) gas chromatography-mass spectrometry (GC-MS). Percent recoveries of the derivatives from sand ranged from 12-69%, and the detection limits were 0.05 ng to 0.20 ng for 1 gram sand samples. Percent recoveries from the same extraction procedures on four mixed soil samples ranged from 0.1 to 32% and experiments to improve recoveries were not successful. Mass spectra of the compounds were also evaluated by electron impact (EI) and positive chemical ionization (PCI), and NICI was found to be the superior method for detection. Difficulties remain in optimizing the extraction process, but the data reveals some interesting fragmentation patterns as well as presenting many questions left to be answered.
Download or read book The Investigation of Negative Ion Chemical Ionization Gas Chromatography Mass Spectrometry as a Routine and Sensitive Detection Method for Residue Analysis of Detagonists and Other Anabolic Agents written by Ita Walsh and published by . This book was released on 1993 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Optimization of the Standard Method of Detection of 4 aminobiphenyl by Negative Ion Chemical Ionization Mass Spectrometry and Investigation of a Method for the Negative Ion Chemical Ionization Detection of N nitrosodimethylamine written by Gary Nelson Lavine and published by . This book was released on 1994 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemical Derivatization in Gas Chromatography written by J. Drozd and published by Elsevier. This book was released on 1986-07-01 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Derivatization in Gas Chromatography
Download or read book Methodologies for Metabolomics written by Norbert W. Lutz and published by Cambridge University Press. This book was released on 2013-01-21 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.
Download or read book Oral Health in America written by and published by . This book was released on 2000 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Profile for Acrolein written by and published by . This book was released on 2007 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemical Biomarkers in Aquatic Ecosystems written by Thomas S. Bianchi and published by Princeton University Press. This book was released on 2011-02-28 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a unique and thorough look at the application of chemical biomarkers to aquatic ecosystems. Defining a chemical biomarker as a compound that can be linked to particular sources of organic matter identified in the sediment record, the book indicates that the application of these biomarkers for an understanding of aquatic ecosystems consists of a biogeochemical approach that has been quite successful but underused. This book offers a wide-ranging guide to the broad diversity of these chemical biomarkers, is the first to be structured around the compounds themselves, and examines them in a connected and comprehensive way. This timely book is appropriate for advanced undergraduate and graduate students seeking training in this area; researchers in biochemistry, organic geochemistry, and biogeochemistry; researchers working on aspects of organic cycling in aquatic ecosystems; and paleoceanographers, petroleum geologists, and ecologists. Provides a guide to the broad diversity of chemical biomarkers in aquatic environments The first textbook to be structured around the compounds themselves Describes the structure, biochemical synthesis, analysis, and reactivity of each class of biomarkers Offers a selection of relevant applications to aquatic systems, including lakes, rivers, estuaries, oceans, and paleoenvironments Demonstrates the utility of using organic molecules as tracers of processes occurring in aquatic ecosystems, both modern and ancient
Download or read book Recent Developments in Mass Spectrometry in Biochemistry and Medicine written by Alberto Frigerio and published by Springer. This book was released on 1978-04-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Profile for Asbestos Update written by G. Douglas Hanley and published by DIANE Publishing. This book was released on 2011 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a print on demand edition of a hard to find publication. Asbestos is a group of 6 different fibrous minerals that occur naturally in the environment. All forms of asbestos are hazardous, and all can cause cancer. This profile includes: (1) The exam¿n. and interpretation of toxicologic info. and epidemiological eval¿s. on asbestos to ascertain the levels of human exposure for the substance and its health effects; (2) A determination of whether adequate info. on the health effects of asbestos is available or in the process of development to determine levels of exposure that present a significant risk to human health; and (3) Where appropriate, identification of toxicologic testing needed to identify the types or levels of exposure that may present significant risk of adverse health effects in humans. Charts and tables.
Download or read book The Commercial Storage of Fruits Vegetables and Florist and Nursery Stocks written by Robert E. Hardenburg and published by . This book was released on 1986 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Note for the electronic edition: This draft has been assembled from information prepared by authors from around the world. It has been submitted for editing and production by the USDA Agricultural Research Service Information Staff and should be cited as an electronic draft of a forthcoming publication. Because the 1986 edition is out of print, because we have added much new and updated information, and because the time to publication for so massive a project is still many months away, we are making this draft widely available for comment from industry stakeholders, as well as university research, teaching and extension staff.
Download or read book Amino Acid Analysis written by Michail A. Alterman and published by Humana Press. This book was released on 2011-12-02 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amino Acid Analysis (AAA) is an integral part of analytical biochemistry. In a relatively short time, the variety of AAA methods has evolved dramatically with more methods shifting to the use of mass spectrometry (MS) as a detection method. Another new aspect is miniaturization. However, most importantly, AAA in this day and age should be viewed in the context of Metabolomics as a part of Systems Biology. Amino Acid Analysis: Methods and Protocols presents a broad spectrum of all available methods allowing for readers to choose the method that most suits their particular laboratory set-up and analytical needs. In this volume, a reader can find chapters describing general as well as specific approaches to the sample preparation. A number of chapters describe specific applications of AAA in clinical chemistry as well as in food analysis, microbiology, marine biology, drug metabolism, even archeology. Separate chapters are devoted to the application of AAA for protein quantitation and chiral AAA. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Amino Acid Analysis: Methods and Protocols provides crucial techniques that can be applied across multiple disciplines by anyone involved in biomedical research or life sciences.
Download or read book Measurement of Antioxidant Activity and Capacity written by Resat Apak and published by John Wiley & Sons. This book was released on 2018-02-20 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive reference for assessing the antioxidant potential of foods and essential techniques for developing healthy food products Measurement of Antioxidant Activity and Capacity offers a much-needed resource for assessing the antioxidant potential of food and includes proven approaches for creating healthy food products. With contributions from world-class experts in the field, the text presents the general mechanisms underlying the various assessments, the types of molecules detected, and the key advantages and disadvantages of each method. Both thermodynamic (i.e. efficiency of scavenging reactive species) and kinetic (i.e. rates of hydrogen atom or electron transfer reactions) aspects of available methods are discussed in detail. A thorough description of all available methods provides a basis and rationale for developing standardized antioxidant capacity/activity methods for food and nutraceutical sciences and industries. This text also contains data on new antioxidant measurement techniques including nanotechnological methods in spectroscopy and electrochemistry, as well as on innovative assays combining several principles. Therefore, the comparison of conventional methods versus novel approaches is made possible. This important resource: Offers suggestions for assessing the antioxidant potential of foods and their components Includes strategies for the development of healthy functional food products Contains information for identifying antioxidant activity in the body Presents the pros and cons of the available antioxidant determination methods, and helps in the selection of the most appropriate method Written for researchers and professionals in the nutraceutical and functional food industries,academia and government laboratories, this text includes the most current knowledge in order to form a common language between research groups and to contribute to the solution of critical problems existing for all researchers working in this field.
Download or read book Current Protocols in Molecular Biology written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Membrane Lipid Oxidation written by Carmen Vigo-Pelfrey and published by CRC-Press. This book was released on 1990-12-05 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume text compiles the efforts of distinguished scientists nd focuses on the formation of free radicals, toxic effects of lipoperoxides, biological antioxidant protection against lipid peroxidation damage, and pathological implications of lipid peroxidation. This review also addresses vitamin E deficiency, carbon tetrachloride and ethanol poisoning, radiation damage, hyperbaric effects, tumors, aging, diabetes, liver degeneration, DNA damage, lipoprotein modification and artherosclerosis, multiple sclerosis, angiopathy, Parkinson's disease, lupus, and many other degenerative diseases. It is an excellent resource for biological chemist, cell biologists, and all who are interested in the pharmaceutical sciences.
Download or read book Liquid Chromatography in Clinical Analysis written by Pokar M. Kabra and published by Springer Science & Business Media. This book was released on 2008-02-07 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liquid Chromatography in Clinical Analysis
Download or read book Phytochemical Methods written by Jeffrey B. Harborne and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: While there are many books available on methods of organic and biochemical analysis, the majority are either primarily concerned with the application of a particular technique (e.g. paper chromatography) or have been written for an audience of chemists or for biochemists work ing mainly with animaltissues. Thus, no simple guide to modern metho ds of plant analysis exists and the purpose of the present volume is to fill this gap. It is primarily intended for students in the plant sciences, who have a botanical or a general biological background. It should also be of value to students in biochemistry, pharmacognosy, food science and 'natural products' organic chemistry. Most books on chromatography, while admirably covering the needs of research workers, tend to overwhelm the student with long lists of solvent systems and spray reagents that can be applied to each class of organic constituent. The intention here is to simplify the situation by listing only a few specially recommended techniques that have wide currency in phytochemical laboratories. Sufficient details are provided to allow the student to use the techniques for themselves and most sections contain some introductory practical experiments which can be used in classwork.
