Download or read book Nanotoxicity written by Susai Rajendran and published by Elsevier. This book was released on 2020-04-09 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotoxicity: Prevention, and Antibacterial Applications of Nanomaterials focuses on the fundamental concepts for cytotoxicity and genotoxicity of nanomaterials. It sheds more light on the underlying phenomena and fundamental mechanisms through which nanomaterials interact with organisms and physiological media. The book provides good guidance for toxic prevention methods and management in the manufacture/application/disposal. The book also discusses the potential applications of nanomaterials-based antibiotics. The potential toxic effects of nanomaterials result not only from the type of base materials, but also from their size/ ligands/surface chemical modifications. This book discusses why different classes of nanomaterials display toxic properties, and what can be done to mitigate this toxicity. It also explores how nanomaterials are being used as antimicrobial agents, being used to purify air and water, and counteract a range of infectious diseases. This is an important reference for materials scientists, environmental scientists and biomedical scientists, who are seeking to gain a greater understanding of how nanomaterials can be used to combat toxic agents, and how the toxicity of nanomaterials themselves can best be mitigated. - Explains the underlying phenomena and fundamental mechanisms through which nanomaterials interact with organisms and physiological media - Outlines major methods for mitigating and prevention of nanotoxicity - Discusses the applications of nanomaterials-based antibiotics

Download or read book Nanotoxicity written by Saura C. Sahu and published by John Wiley & Sons. This book was released on 2009-08-04 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials - substances smaller than 100 nanometers in size - have been added in recent years to an increasing numbers of consumer products used in day-to-day life; in food packaging, medical devices, pharmaceuticals, cosmetics, odor-resistant textiles and household appliances. The extensive application of nanomaterials in a wide range of products for human use poses a potential for toxicity risk to human health and the environment. Such adverse effects of nanomaterials on human health have triggered the development of a new scientific discipline known as “nanotoxicity” – the study of the toxicity of nanomaterials. Nanotoxicity: From in vivo and in vitro Models to Health Risks provides up-to-date state-of-the-art information presented by recognized experts in this emerging new field in toxicology. It discusses the safety evaluation of nanomaterials in foods, drugs, medical devices, cosmetics and other regulated products and its use in risk analysis for potential regulatory use. Topics covered include: biomarkers for nanotoxicity assessment nanotoxicity assessment by gene expression analysis in vivo and in vitro models for nanotoxicity testing mechanisms of nanotoxicity pharmakokinetics of nanomaterials nanotoxicity of foods including food processing, food packaging and food safety nanotoxicity of drugs including drug development and drug delivery nanotoxicity of cosmetics and consumer products health and environmental impact of nanotoxicity safety evaluation of nanomaterials regulatory impact of nanomaterials Nanotoxicity: From in vivo and in vitro Models to Health Risks is a valuable authoritative source of information for readers from a wide range of disciplines such as toxicology, pharmacology, drug toxicity and food and environmental sciences. The book will be useful to the research community in academia, industry, hospitals and government, as well as to government regulators and risk assessors of foods, drugs and environmental and agricultural products.

Download or read book Nanotoxicity written by Qunwei Zhang and published by . This book was released on 2018 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nanotoxicology written by Hemant Kumar Daima and published by CRC Press. This book was released on 2021-07-15 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of nanomedicine has risen quickly due to the increasing number of designer-made nanomaterials. These nanomaterials have the potential to manage diseases and change the way medicine is currently studied. However, the increased practice of using nanomaterials has shed light on how many concepts of nanomedicine and nanotoxicity have been overlooked. Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications addresses the existing gaps between nanomedicine and nanotoxicity. This book also brings together up-to-date knowledge on advances toward safe-by-design nanomaterials and existing toxicity challenges. This book delivers a comprehensive coverage in the field with fundamental understanding, serving as a platform to convey essential concepts of nanotoxicology and how these concepts can be employed to develop advanced nanomaterials for a range of biomedical applications. This book is an effort to answer some of the thoughtful nanotoxicological complications and their auspicious probable solutions with new approaches and careful toxicity assessment. Key Features: Reveals novel nanoscale approaches, toxicity assessment, and biomedical applications Includes importance of nanotoxicity concepts in developing smart nanomaterials Highlights unique contributions and "A to Z" aspects on the state-of-the-art from global leaders Offers a complete package to learn fundamentals with recommendations on nanomaterials toxicity and safe-by-design nanomedicines Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications illuminates the high potential of many innovative nanomaterials, ultimately demonstrating them to be promising substitutes for available therapies that can be effectively used in fighting a myriad of biomedical complications. Further, this book reports legal, ethical, safety, and regulatory issues associated with nanomaterials, which have often been neglected, if not overlooked in literature and limiting clinical translation at nanoscale level. It will equip readers with cutting-edge knowledge of promising developments in nanomedicine and nanotoxicology, along with potential future prospects.

Download or read book Modeling of Nanotoxicity written by Ruhong Zhou and published by Springer. This book was released on 2015-09-04 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the fundamentals of nanotoxicity modeling and its implications for the development of novel nanomedicines. It lays out the fundamentals of nanotoxicity modeling for an array of nanomaterial systems, ranging from carbon-based nanoparticles to noble metals, metal oxides, and quantum dots. The author illustrates how molecular (classical mechanics) and atomic (quantum mechanics) modeling approaches can be applied to bolster our understanding of many important aspects of this critical nanotoxicity issue. Each chapter is organized by types of nanomaterials for practicality, making this an ideal book for senior undergraduate students, graduate students, and researchers in nanotechnology, chemistry, physics, molecular biology, and computer science. It is also of interest to academic and industry professionals who work on nanodrug delivery and related biomedical applications, and aids readers in their biocompatibility assessment efforts in the coming age of nanotechnology. This book also provides a critical assessment of advanced molecular modeling and other computational techniques to nanosafety, and highlights current and future biomedical applications of nanoparticles in relation to nanosafety.

Download or read book The ELSI Handbook of Nanotechnology written by Chaudhery Mustansar Hussain and published by John Wiley & Sons. This book was released on 2020-03-31 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook focuses on the recent advancements in Safety, Risk, Ethical Society and Legal Implications (ESLI) as well as its commercialization of nanotechnology, such as manufacturing. Nano is moving out of its relaxation phase of scientific route, and as new products go to market, organizations all over the world, as well as the general public, are discussing the environmental and health issues associated with nanotechnology. Nongovernmental science organizations have long since reacted; however, now the social sciences have begun to study the cultural portent of nanotechnology. Societal concerns and their newly constructed concepts, show nanoscience interconnected with the economy, ecology, health, and governance. This handbook addresses these new challenges and is divided into 7 sections: Nanomaterials and the Environment; Life Cycle Environmental Implications of Nanomanufacturing; Bioavailability and Toxicity of Manufactured Nanoparticles in Terrestrial Environments; Occupational Health Hazards of Nanoparticles; Ethical Issues in Nanotechnology; Commercialization of Nanotechnology; Legalization of Nanotechnology.

Download or read book Nanotechnology in Medicine written by Mahendra Rai and published by John Wiley & Sons. This book was released on 2021-10-19 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: NANOTECHNOLOGY IN MEDICINE Discover thorough insights into the toxicology of nanomaterials used in medicine In Nanotechnology in Medicine: Toxicity and Safety, an expert team of nanotechnologists delivers a robust and up-to-date review of current and future applications of nanotechnology in medicine with a special focus on neurodegenerative diseases, cancer, diagnostics, nano-nutraceuticals, dermatology, and gene therapy. The editors offer resources that address nanomaterial safety, which tends to be the greatest hurdle to obtaining the benefits of nanomedicine in healthcare. The book is a one-stop resource for recent and comprehensive information on the toxico logical and safety aspects of nanotechnology used in human health and medicine. It provides readers with cutting-edge techniques for delivering therapeutic agents into targeted cellular compartments, cells, tissues, and organs by using nanoparticulate carriers. The book also offers methodological considerations for toxicity, safety, and risk assessment. Nanotechnology in Medicine: Toxicity and Safety also provides readers with: A thorough introduction to the nanotoxicological aspects of nanomedicine, including translational nanomedicine and nanomedicine personalization Comprehensive introductions to nanoparticle toxicity and safety, including selenium nanoparticles and metallic nanoparticles Practical discussions of nanotoxicology and drug delivery, including gene delivery using nanocarriers and the use of nanomaterials for ocular delivery applications In-depth examinations of nanotechnology ethics and the regulatory framework of nanotechnology and medicine Perfect for researchers, post-doctoral candidates, and specialists in the fields of nanotechnology, nanomaterials, and nanocarriers, Nanotechnology in Medicine: Toxicity and Safety will also prove to be an indispensable part of the libraries of nanoengineering, nanomedicine, and biopharmaceutical professionals and nanobiotechnologists.

Download or read book Nanotoxicology for Agricultural and Environmental Applications written by Mahendra Rai and published by Elsevier. This book was released on 2024-03-28 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published as part of Elsevier’s series, Nanobiotechnology for Plant Protection, Nanotoxicology for Agricultural and Environmental Applications provides an introduction to nanotechnology and its applications in agriculture and the environment.Divided into five parts, this book addresses nanotechnology and regulations, nanotoxicity, nanotoxicity to agriculture and food, nanotoxicity to the environment, and risk management measures to avoid exposure.Students, practitioners, and researchers working in plant science, agricultural science, nanoscience, and environmental chemistry alike will benefit from this necessary reference. Highlights the factors contributing to toxic effects of nanoparticles, including shape, size, structure, surface charge, and dosage Explores the mode of action and entry of nanoparticles, methods of toxicity evaluation, and the associated challenges Describes recent developments in nanotoxicity to soil ecosystems, crop plants, and food systems Emphasizes the impact of nanoparticles and their detoxification by plants on the nutritional quality of food and plants Discusses the impact of toxicity of nanoparticles released in air, soil, and water and methods to reduce their effects

Download or read book Nanomedicine Manufacturing and Applications written by Francis Verpoort and published by Elsevier. This book was released on 2021-06-22 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedicine explores the modification and enhancement of the properties and performances of typical drugs to treat various diseases. Nano-based medicines have advantages in several ways, such as in nanotherapeutics, nanotheranostics, and nanodiagnostics. Nanomedicine Manufacturing and Applications effectively explores the major manufacturing techniques and applications of nanomaterial-based medicine in the areas of chemotherapy, biochips, insulin pumps, and other treatment methods. This book explains how nanomedicines are developed from nanoparticles as well as their biomedical and other applications related to healthcare. This book is an important reference source for nanoscientists, biomaterials scientists, and biomedical engineers who want to learn more about how nano-based medicines are made and used. Outlines the process of making nanomedicine as well as nanodrug carriers, with a focus on nanomedicine for cancer treatment. Explains the formulation and manufacturing process of nanomedicines, showing how to build these materials. Demonstrates how nano-based medicines are being used to tackle a range of diseases in a way that conventional medicines cannot.

Download or read book Neurotoxicity of Nanomaterials and Nanomedicine written by Xinguo Jiang and published by Academic Press. This book was released on 2016-10-03 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurotoxicity of Nanomaterials and Nanomedicine presents an overview of the exciting research in neurotoxicity and nanomaterials. Nanomaterials have been extensively used in medicine, including diagnosis probes, drug carriers, and embedded materials. While some have been approved for clinical use, most nanomaterials are waiting to be transferred from lab to clinic. However, the toxicity is a main barrier that restricts the translation. This comprehensive book includes chapters on the most commonly used individual nanoparticles, with information on the applications, neurotoxicity, and related mechanisms of each, providing the most in-depth and current information available. The book examines the pathways that nanomaterials enter into, and eliminate, from the brain, along with the strategies that could reduce the neurotoxicity of nanomaterials. Providing a background to the subject, detailed information, and ideas for future directions in research, the book is essential for students and researchers in toxicology, and for those in medicine, neurology, pharmacology, pharmaceutical science, and materials science who are researching nanomaterials. Presents a thorough discussion of the most common nanoparticles in the brain and their neurotoxicology Includes the most common nanoparticles, their applications, and mechanisms Provides one of the first books to focus on nanomedicine and neurotoxicity

Download or read book Nanotoxicology and Nanoecotoxicology Vol 1 written by Vineet Kumar and published by Springer Nature. This book was released on 2021-04-13 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the basics of nanotoxicity and gives a detailed account of methods used for toxicity evaluation of nanomaterials. It also gives indepth coverage of the effect of different types of nanomaterials, including organic and inorganic, on various aquatic animals, microorganisms and plants, and outlines recent challenges, regulatory frameworks and advances in nanotoxicity testing.

Download or read book Nanotoxicology written by Nelson Durán and published by Springer Science & Business Media. This book was released on 2013-10-25 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes a systematic approach to nanotoxicology and the developing risk factors associated with nanosized particles during manufacture and use of nanotechnology. Beginning with a detailed introduction to engineered nanostructures, the first part of the book presents concepts and definitions of nanomaterials from quantum dots to graphene to fullerenes, with detailed discussion of functionalization, stability, and medical and biological applications. The second part critically examines methodologies used to assess cytotoxicity and genotoxicity. Coverage includes interactions with blood (erythrocytes), combinatorial and microarray techniques, cellular mechanisms, and ecotoxicology assessments. Part three describes cases studies both in vitro and in vivo for specific nanomaterials including solid lipid nanoparticles and nanostructured lipid carriers and metallic nanoparticles and metallic oxides. New information is also presented on toxicological aspects of poloxamers and polymeric nanoparticles as drug carriers as well as size effects on cytotoxicity and genotoxicity. Didactic aspects are emphasized in all chapters, making the book suitable for a broad audience ranging from advanced undergraduate and graduate students to researchers in academia and industry. In all, Nanotoxicology: Materials, Methodologies, and Assessments will provide comprehensive insight into biological and environmental interactions with nanostructures. Provides an introduction to nanostructures actually in use Describes cyto- and genotoxicity methodologies, and assesses their performance in comparison to common toxicity assays Discusses the relation of cytotoxicity and genotoxicity to ecotoxicity Presents a range of applications, from biogenic silver nanoparticles to poloxamers as drug-delivery systems, reflecting the expanding applications of nanotechnology

Download or read book Nanotoxicology written by Vineet Kumar and published by CRC Press. This book was released on 2018-03-12 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the application of nanotechnology in the myriad disciplines of science and engineering--from agriculture, pharmaceuticals, material science, and biotechnology to sensors, electronics, and mechanical and electrical engineering--brings benefits it also can produce serious threats to human health and the environment that must be evaluated. The unique properties of nanomaterials make them different from their bulk counterparts. In addition to such unique properties, the nanometric size of nanomaterials can invite some detrimental effects on the health and well-being of living organisms and the environment. Thus, it is important to distinguish nanomaterials with such ill effects from nanomaterials with no or minimum toxicity. Nanotoxicology: Toxicity Evaluation, Risk Assessment and Management covers issues such as the basic principles of nanotoxicity, methods used for nanotoxicity evaluation, risk assessment and its management for nanomaterial toxicity with a focus on current trends, limitations, challenges, and future directions of nanotoxicity evaluation. Various experts from different countries discuss these issues in detail in this book. This will be helpful to researchers, educators, and students who are interested in research opportunities for avoiding the environmental and health hazards of nanomaterials. This book will also be useful for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, drugs, and other regulatory sciences.

Download or read book Nanocosmetics written by Arun Nanda and published by Elsevier. This book was released on 2020-05-06 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is key to the design and manufacture of the new generation of cosmetics. Nanotechnology can enhance the performance and properties of cosmetics, including colour, transparency, solubility, texture, and durability. Sunscreen products, such as UV nano-filters, nano-TiO2 and nano-ZnO particles, can offer an advantage over their traditional counterparts due to their broad UV-protection and non-cutaneous side effects. For perfumes, nano-droplets can be found in cosmetic products including Eau de Toilette and Eau de Parfum. Nanomaterials can also be used in cosmetics as transdermal drug delivery systems. By using smart nanocontainers, active compounds such as vitamins, antioxidants, nutrients, and anti-inflammatory, anti-infective agents, can be delivered effectively. These smart nanocontainers are typically related with the smart releasing property for their embedded active substances. These smart releases could be obtained by using the smart coatings as their outer nano-shells. These nano-shells could prevent the direct contact between these active agents and the adjacent local environments. Nanocosmetics: Fundamentals, Applications and Toxicity explores the formulation design concepts and emerging applications of nanocosmetics. The book also focuses on the mitigation or prevention of their potential nanotoxicity, potential global regulatory challenges, and the technical challenges of mass implementation. It is an important reference source for materials scientists and pharmaceutical scientists looking to further their understanding of how nanotechnology is being used for the new generation of cosmetics. - Outlines the major fabrication and formulation design concepts of nanoscale products for cosmetic applications - Explores how nanomaterials can safely be used for various applications in cosmetic products - Assesses the major challenges of using nanomaterials for cosmetic applications on a large scale

Download or read book Nanotoxicology written by Alok Dhawan and published by Royal Society of Chemistry. This book was released on 2017-11-03 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid expansion of the nanotechnology field raises concerns, like any new technology, about the toxicity and environmental impact of nanomaterials. This book addresses the gaps relating to health and safety issues of this field and aims to bring together fragmented knowledge on nanosafety. Not only do chapters address conventional toxicity issues, but also more recent developments such as food borne nanoparticles, life cycle analysis of nanoparticles and nano ethics. In addition, the authors discuss the environmental impact of nanotechnologies as well as safety guidelines and ethical issues surrounding the use of nanoparticles. In particular this book presents a unique compilation of experimental and computational perspectives and illustrates the use of computational models as a support for experimental work. Nanotoxicology: Experimental and Computational Perspectives is aimed towards postgraduates, academics, and practicing industry professionals. This highly comprehensive review also serves as an excellent foundation for undergraduate students and researchers new to nanotechnology and nanotoxicology. It is of particular value to toxicologists working in nanotechnology, chemical risk assessment, food science, environmental, safety, chemical engineering, the biological sciences and pharmaceutical research.

Download or read book Computational Nanotoxicology written by Agnieszka Gajewicz and published by CRC Press. This book was released on 2019-11-13 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of computational methods that support human health and environmental risk assessment of engineered nanomaterials (ENMs) has attracted great interest because the application of these methods enables us to fill existing experimental data gaps. However, considering the high degree of complexity and multifunctionality of ENMs, computational methods originally developed for regular chemicals cannot always be applied explicitly in nanotoxicology. This book discusses the current state of the art and future needs in the development of computational modeling techniques for nanotoxicology. It focuses on (i) computational chemistry (quantum mechanics, semi-empirical methods, density functional theory, molecular mechanics, molecular dynamics), (ii) nanochemoinformatic methods (quantitative structure–activity relationship modeling, grouping, read-across), and (iii) nanobioinformatic methods (genomics, transcriptomics, proteomics, metabolomics). It reviews methods of calculating molecular descriptors sufficient to characterize the structure of nanoparticles, specifies recent trends in the validation of computational methods, and discusses ways to cope with the uncertainty of predictions. In addition, it highlights the status quo and further challenges in the application of computational methods in regulation (e.g., REACH, OECD) and in industry for product development and optimization and the future directions for increasing acceptance of computational modeling for nanotoxicology.

Download or read book Nanoscience and Nanotechnology written by Vicki H. Grassian and published by John Wiley & Sons. This book was released on 2008-12-19 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book covers various aspects of nanoscience and nanotechnology and what is known about the potential environmental and health impacts. Divided into three main sections, the book addresses the toxicity of nanomaterials, fate and transport of nanomaterials in the environment, and occupational health aspects of nanotechonology.