Download or read book Multistep Continuous Flow Synthesis of Fine Chemicals with Heterogeneous Catalysts written by Yuki Saito and published by Springer. This book was released on 2022-12-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the development of two kinds of continuous-flow transformation using heterogeneous catalysts, and explains how they can be applied in the multistep synthesis of active pharmaceutical ingredients. It demonstrates and proves that fine chemicals can be synthesized under continuous-flow conditions using heterogeneous catalysis alone. Importantly, the book also proposes a general concept and strategy for achieving multistep flow synthesis and developing heterogeneous catalysts, and shows that commercially available anion exchange resin can be used as a water-tolerant strong base catalyst for various types of continuous-flow aldol-type reaction. Reviewing the state of the art in heterogeneous catalysis in flow chemistry – a “hot topic” and rapidly developing area of organic synthesis – the book will provide readers with a deeper understanding of fine chemical flow synthesis and its future prospects.
Download or read book Multistep Continuous Flow Synthesis of Fine Chemicals with Heterogeneous Catalysts written by Yuki Saito and published by Springer Nature. This book was released on 2022-11-30 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the development of two kinds of continuous-flow transformation using heterogeneous catalysts, and explains how they can be applied in the multistep synthesis of active pharmaceutical ingredients. It demonstrates and proves that fine chemicals can be synthesized under continuous-flow conditions using heterogeneous catalysis alone. Importantly, the book also proposes a general concept and strategy for achieving multistep flow synthesis and developing heterogeneous catalysts, and shows that commercially available anion exchange resin can be used as a water-tolerant strong base catalyst for various types of continuous-flow aldol-type reaction. Reviewing the state of the art in heterogeneous catalysis in flow chemistry – a “hot topic” and rapidly developing area of organic synthesis – the book will provide readers with a deeper understanding of fine chemical flow synthesis and its future prospects.
Download or read book Flow Chemistry Applications written by Ferenc Darvas and published by Walter de Gruyter GmbH & Co KG. This book was released on 2014-11-18 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Flow Chemistry fills the gap in graduate education by covering chemistry and reaction principles along with current practice, including examples of relevant commercial reaction, separation, automation, and analytical equipment. The Editors of Flow Chemistry are commended for having taken the initiative to bring together experts from the field to provide a comprehensive treatment of fundamental and practical considerations underlying flow chemistry. It promises to become a useful study text and as well as reference for the graduate students and practitioners of flow chemistry." Professor Klavs Jensen Massachusetts Institute of Technology, USA Broader theoretical insight in driving a chemical reaction automatically opens the window towards new technologies particularly to flow chemistry. This emerging concept promotes the transformation of present day's organic processes into a more rapid continuous set of synthesis operations, more compatible with the envisioned sustainable world. These two volumes Fundamentals and Applications provide both the theoretical foundation as well as the practical aspects.
Download or read book Catalytic Asymmetric Synthesis written by Takahiko Akiyama and published by John Wiley & Sons. This book was released on 2022-05-27 with total page 798 pages. Available in PDF, EPUB and Kindle. Book excerpt: Catalytic Asymmetric Synthesis Seminal text presenting detailed accounts of the most important catalytic asymmetric reactions known today This book covers the preparation of enantiomerically pure or enriched chemical compounds by use of chiral catalyst molecules. While reviewing the most important catalytic methods for asymmetric organic synthesis, this book highlights the most important and recent developments in catalytic asymmetric synthesis. Edited by two well-qualified experts, sample topics covered in the work include: Metal catalysis, organocatalysis, photoredox catalysis, enzyme catalysis C–H bond functionalization reactions Carbon–carbon bond formation reactions, carbon–halogen bond formation reactions, hydrogenations, polymerizations, flow reactions Axially chiral compounds Retaining the best of its predecessors but now thoroughly up to date with the important and recent developments in catalytic asymmetric synthesis, the 4th edition of Catalytic Asymmetric Synthesis serves as an excellent desktop reference and text for researchers and students, from upper-level undergraduates all the way to experienced professionals in industry or academia.
Download or read book Flow Chemistry in Drug Discovery written by Jesus Alcazar and published by Springer Nature. This book was released on 2021-12-08 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the challenges and opportunities posed by flow chemistry in drug discovery, and offers a handy reference tool for medicinal chemists interested in the synthesis of biologically active compounds. Prepared by expert contributors, the respective chapters cover not only fundamental methodologies and reactions, such as the application of catalysis, especially biocatalysis and organocatalysis; and non-conventional activation techniques, from photochemistry to electrochemistry; but also the development of new process windows, processes and reactions in drug synthesis. Particular attention is given to automatization and library synthesis, which are of great importance in the pharmaceutical industry. Readers will also find coverage on selected topics of general interest, such as how flow chemistry is contributing to drug discovery R&D in developing countries, and the green character of this enabling technology, for example in the production of raw materials for the pharmaceutical industry from waste. Given its scope, the book appeals to medicinal chemistry researchers working in academia and industry alike, as well as professionals involved in scale-up and drug development.
Download or read book Methods and Strategies for C N Bond Formation Reactions written by Zahra Taherinia and published by Royal Society of Chemistry. This book was released on 2023-12-15 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Catalytic Methods in Flow Chemistry written by Christophe Len and published by MDPI. This book was released on 2020-04-15 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chemical industry is essential in the daily humn life of modern society; despite the misconception about the real need for chemical production, everyone enjoys the benefit of the chemical progress. However, the chemical industry generates a large variety of products, including (i) basic chemicals, e.g., polymers, petrochemicals, and basic inorganics; (ii) specialty chemicals for crop protection, paints, inks, colorants, textiles, paper, and engineering; and (iii) consumer chemicals, including detergents, soaps, etc. For these reasons, chemists in both acdemia and industry are challenged with developing green and sustainable chemical production towrad the full-recycling of feedstocks and waste. Aiming to improve the intensification of the process, chemists have established chemical reactions based on catalysis, as well as alternative technologies, such as continuous flow. The aim of this book is to cover promising recent research and novel trends in the field of novel catalytic reactions (homogeneous, heterogeneous, and enzymatic, as well as their combinations) in continuous flow conditions. A collection of recent contribution for conversion of starting material originated from petroleum resources or biomass into highly-added value chemicals are reported.
Download or read book Applied Biocatalysis in Europe written by Andres R. Alcantara and published by MDPI. This book was released on 2021-08-30 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applied biocatalysis and biotransformation, that is, the use of enzymes and whole-cell systems in manufacturing processes for synthetic purposes, has been experiencing a clear boom in recent years, which has led to the start of the so-called “fourth wave”. In fact, the latest advances in bioinformatics, system biology, process intensification, and, in particular, enzyme-directed evolution (encouraged by the 2018 Nobel Prize awarded to F. Arnold), are widening the range of the efficacy of biocatalysts and accelerating the rate at which new enzymes are becoming available, even for activities not previously known. European scientists have been very actively involved in different aspects of this field. Nine contributions dealing with different aspects of applied biocatalysis developed by European researchers are gathered in this Special Issue
Download or read book Heterogenized Homogeneous Catalysts for Fine Chemicals Production written by Pierluigi Barbaro and published by Springer Science & Business Media. This book was released on 2010-09-02 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Table 1 E factors (tonnes of waste generated per tonne of product manufactured [7] Industry segment Annual product tonnage E factor 6 8 Oil refining 10 –10 Approx. 0. 1 4 6 Bulk chemicals 10 –10
Download or read book Fine Chemicals Through Heterogeneous Catalysis written by R. A. Sheldon and published by LibreDigital. This book was released on 2008-07-11 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowadays, the chemical industry is under increased pressure to develop cleaner production processes and technologies. Much effort is devoted to the development of heterogeneous catalysts and their application in industrial-scale organic synthesis. This handbook concentrates on current attempts, focusing on fine chemical production. With contributions from an impressive array of international experts, this is essential reading for everyone interested in the advances in this field.
Download or read book Process Intensification Technologies for Green Chemistry written by Kamelia Boodhoo and published by John Wiley & Sons. This book was released on 2013-01-03 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: The successful implementation of greener chemical processes relies not only on the development of more efficient catalysts for synthetic chemistry but also, and as importantly, on the development of reactor and separation technologies which can deliver enhanced processing performance in a safe, cost-effective and energy efficient manner. Process intensification has emerged as a promising field which can effectively tackle the challenges of significant process enhancement, whilst also offering the potential to diminish the environmental impact presented by the chemical industry. Following an introduction to process intensification and the principles of green chemistry, this book presents a number of intensified technologies which have been researched and developed, including case studies to illustrate their application to green chemical processes. Topics covered include: • Intensified reactor technologies: spinning disc reactors, microreactors, monolith reactors, oscillatory flow reactors, cavitational reactors • Combined reactor/separator systems: membrane reactors, reactive distillation, reactive extraction, reactive absorption • Membrane separations for green chemistry • Industry relevance of process intensification, including economics and environmental impact, opportunities for energy saving, and practical considerations for industrial implementation. Process Intensification for Green Chemistry is a valuable resource for practising engineers and chemists alike who are interested in applying intensified reactor and/or separator systems in a range of industries to achieve green chemistry principles.
Download or read book 32nd European Symposium on Computer Aided Process Engineering written by Ludovic Montastruc and published by Elsevier. This book was released on 2022-06-30 with total page 1760 pages. Available in PDF, EPUB and Kindle. Book excerpt: 32nd European Symposium on Computer Aided Process Engineering: ESCAPE-32 contains the papers presented at the 32nd European Symposium of Computer Aided Process Engineering (ESCAPE) event held in Toulouse, France. It is a valuable resource for chemical engineers, chemical process engineers, researchers in industry and academia, students and consultants for chemical industries who work in process development and design. Presents findings and discussions from the 32nd European Symposium of Computer Aided Process Engineering (ESCAPE) event
Download or read book 34th European Symposium on Computer Aided Process Engineering 15th International Symposium on Process Systems Engineering written by Flavio Manenti and published by Elsevier. This book was released on 2024-06-28 with total page 3634 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering, contains the papers presented at the 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering joint event. It is a valuable resource for chemical engineers, chemical process engineers, researchers in industry and academia, students, and consultants for chemical industries. Presents findings and discussions from the 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering joint event
Download or read book Flow Chemistry written by Santiago V Luis and published by Royal Society of Chemistry. This book was released on 2019-09-18 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Historically pharmaceutical and fine chemical products have been synthesised using batch methods, but increasingly chemists are looking towards flow chemistry as a greener and more efficient alternative. In flow chemistry reactions are performed in a reactor with the reactants pumped through it. It has the benefit of being easily scaled up and it is straightforward to integrate synthesis, workup and analysis into one system. Flow chemistry is considered a greener alternative to batch chemistry because it is easier to control and minimise hazardous intermediates and by-products. There is significant interest in the use of flow chemistry both in the lab and on an industrial scale. Flow Chemistry provides an update on recent advances that have been made in the field. Particular emphasis is given to the new integrated approaches that bring together several elements to implement flow processes as a regular green chemistry tool for the chemical industries. With chapter contributions from several well-known experts in the field, this book is a valuable resource for researchers working in green chemistry and synthesis, chemical engineers and industrial chemists working in the pharmaceutical and fine chemicals industries.
Download or read book Modern Applications of High Throughput R D in Heterogeneous Catalysis written by Alfred Hagemeyer and published by Bentham Science Publishers. This book was released on 2014-04-04 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook covers the application of high-throughput R&D to both fundamental and applied catalysis including catalyst synthesis, characterization, and testing in various reactor types. Chapters include topics such as applications ranging from optimizations of established industrial catalysts to the discovery of innovative new materials, examples of the development of innovative parallel characterization methods, and cases of real catalyst testing in small scale reactor systems. Readers will also find chapters that cover commodity chemicals produced using continuous gas phase processes as well as fine chemicals produced in liquid phase batch reactors. The potential of industrial chemicals production from biorenewable feedstocks is also presented. The steadily improving high throughput workflows are today being applied to relevant reactions and targets such as hydrotreating, Deacon oxidation, Fischer-Tropsch, propane dehydrogenation, C4 oxidation, methane coupling, exhaust gas catalysis, bio-based Nylon, fuel cells and vitamins. The topics presented in this eBook have been contributed by researchers from academia as well as industry, making this eBook a well-balanced reference, which could be of particular interest to professional, industrial or service R&D labs.
Download or read book Biocatalysis for Practitioners written by Gonzalo de Gonzalo and published by John Wiley & Sons. This book was released on 2021-07-19 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book originates from the interdisciplinary research cooperation between academia and industry. In three distinct parts, latest results from basic research on stable enzymes are explained and brought into context with possible industrial applications. Downstream processing technology as well as biocatalytic and biotechnological production processes from global players display the enormous potential of biocatalysts. Application of "extreme" reaction conditions (i.e. unconventional, such as high temperature, pressure, and pH value) - biocatalysts are normally used within a well defined process window - leads to novel synthetic effects. Both novel enzyme systems and the synthetic routes in which they can be applied are made accessible to the reader. In addition, the complementary innovative process technology under unconventional conditions is highlighted by latest examples from biotech industry.
Download or read book Metal Organic Frameworks as Heterogeneous Catalysts written by Francesc X. Llabrés i Xamena and published by Royal Society of Chemistry. This book was released on 2013-07-01 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the latest research and discovery in the use of MOFs in catalysis, highlighting the extent to which these materials have been embraced by the community.
