Download or read book Mouse Molecular Embryology written by Mark Lewandoski and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Mouse Molecular Embryology: Methods and Protocols, expert researchers in the field detail many of the protocols used to study mouse embryology. These include protocols and techniques that are "close to the embryo": such as, manipulating embryonic gene expression, culturing explanted embryonic tissue and harvesting embryonic RNA. With additional chapters on fluorescence imaging, lineage tracing, and genetic ablation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Mouse Molecular Embryology: Methods and Protocols seeks to aid scientist in the further study of mouse embryo and its relation to other aspects of biological research.
Download or read book Mouse Molecular Embryology written by Mark Lewandoski and published by Humana Press. This book was released on 2013-12-28 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Embryology written by Paul T. Sharpe and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most people have some interest in embryos; this probably results, in part, from their interest in understanding the biological origins of themselves and their offspring and, increasingly, concerns about how environmental change such as pollution might affect human development. Obviously, et- cal considerations preclude experimental studies of human embryos and, c- sequently, the developmental biologist has turned to other species to examine this process. Fortunately, the most significant conclusion to be drawn from the experimental embryology of the last two decades is the manner in which orthologous or closely related molecules are deployed to mediate similar - velopmental processes in both vertebrates and invertebrates. The molecular mechanisms regulating processes fundamental to most animals, such as axial patterning or axon guidance, are frequently conserved during evolution. (It is now widely believed that the differences between phyla and classes are the result of new genes, arising mostly by duplication and divergence of extant sequences, regulating the appearance of derived characters. ) Other vertebrates are obviously most likely to use the same devel- mental mechanisms as humans and, within the vertebrate subphylum, the - parent degree of conservation of developmental mechanism is considerable. It has long been recognized that particular vertebrate species offer either d- tinct advantages in investigating particular stages of development or are - pecially amenable to particular manipulations. No single animal can provide all the answers because not all types of experiments can be carried out on a single species.
Download or read book Manipulating the Mouse Embryo written by Andras Nagy and published by Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press. This book was released on 2003 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides background information and detailed protocols for developing a mouse colony and using the animals in transgenic and gene-targeting experiments. The protocols list the animals, equipment, and reagents required and step-by-step procedures. Topics include in vitro culture of preimplantation embryos, surgical procedures, the production of chimeras, and the analysis of genome alterations. The third edition adds protocols for cloning mice, modifying embryonic stem cells, intracytoplasmic sperm injection, and cryopreservation of embryos.
Download or read book Manipulating the Mouse Embryo written by Richard Behringer and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 4th edition of the "Mouse Manual"-Manipulating the Mouse Embryo-appears 28 years after the first edition and once again is the definitive reference source on mouse development, transgenesis techniques, and molecular biology. Authors Richard Behringer, Marina Gertsenstein, Kristina Nagy, and Andras Nagy-pre-emininent leaders in their fields-have reorganized and updated this edition to include new information and protocols on: * assisted reproduction techniques for sperm and embryo cryopreservation * generation of induced pluripotent stem cells * isolation, generation, and transplantation of spermatogonial stem cell lines * in utero electroporation of gene constructs into post- implantation embryos * vibratome sectioning of live and fixed tissues for imaging thick tissue sections * whole-mount fluorescent staining methods for three-dimensional visualization. Techniques regarding recombinant DNA technology and mouse embryonic development from the previous editions have been updated and recast, as has the wealth of information on mouse laboratory strains, mouse housing and breeding, surgical procedures, assisted reproduction, handling of embryos, and micromanipulation setups. The first edition of Manipulating the Mouse Embryo appeared in 1986 as an outgrowth of Cold Spring Harbor Laboratory courses on the molecular embryology of the mouse held in the early 1980s, and authors of the first two editions included Brigid Hogan, Rosa Beddington, Frank Costantini, and Liz Lacy. Mouse embryo manipulation techniques have developed exponentially since the first edition, but then, as now, Manipulating the Mouse Embryo remains the essential practical and theoretical guide for anyone working with mice-students, lab technicians, and investigators.
Download or read book The House Mouse written by Karl Theiler and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the advent of transgenic technology, which allows the identification of specific gene activities in developing mammalian organisms, the house mouse has once again taken a very important place in experimental research as one of the genetically best understood mammals. More than ever, molecular biologists are in need of a detailed, standardized description of the anatomy of the developing mouse embryo. In this classic compendium, now brought up to date and corrected, the author presents each stage of mouse development in photographs and micrographs using hybrids of two inbred strains as a standard. Organ systems are systematically reconstructed from fertilization until after birth. Molecular biologists tracing the effects of genetic manipulations, as well as students and researchers of developmental biology, will appreciate the renewed availability of this standard reference work for its unparalleled accuracy, its attention to anatomical detail, and the extent of its documentation.
Download or read book Manipulating the Mouse Embryo written by Brigid Hogan and published by Cold Spring Harbor Laboratory Press. This book was released on 1986 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of mouse development -- Setting up a colony for the production of transgenic mice -- Recovery, culture, and transfer of embryos -- Introduction of new genetic information into the developing mouse embryo -- Iolation of pluripotential stem cell lines -- Techhniques for visualizing genes and gene products -- In vitro culture of eggs, embryos, and teratocarcinoma cels -- Chemicals, supplies, and solutions.
Download or read book Mouse Development written by Jacek Z. Kubiak and published by Springer Science & Business Media. This book was released on 2012-08-23 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mouse is a perfect model organism to study mammalian, and thus indirectly also human, embryology. Most scientific achievements that have had an important impact on the understanding of basic mechanisms governing embryo development in humans, originated from mouse embryology. Stem cell research, which now offers the promise of regenerative medicine, began with the isolation and culture of mouse embryonic stem cells by Martin Evans (who received the Nobel Prize in medicine in 2007 for this achievement) and Matthew Kaufman. This book provides an overview of mouse development, spanning from oocytes before fertilization to the state-of-the-art description of embryonic and adult stem cells. The chapters, written by the leading specialists in the field, deal with the most recent discoveries in this extremely fast-developing area of research.
Download or read book Kaufman s Atlas of Mouse Development Supplement written by Richard Baldock and published by Academic Press. This book was released on 2015-09-23 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. Provides high-resolution images for best visualization of key developmental processes and structures Offers in-depth anatomy and morphological views of organ systems Written descriptions convey developmental origins of the organ systems
Download or read book The Atlas of Mouse Development written by Matthew H. Kaufman and published by Academic Press. This book was released on 1992-09 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not since the early 1970s has there been an attempt to describe and illustrate the anatomy of the developing mouse embryo. More than ever such material is needed by biologists as they begin to unravel the molecular mechanisms underlying development and differentiation. After more than ten years of painstaking work, Matt Kaufman has completed The Atlas of Mouse Development--the definitive account of mouse embryology and development. For all those researching or studying mammalian development, The Atlas of Mouse Development will be the standard reference work for many years to come. Provides a comprehensive sequential account of the development of the mouse from pre-implantation to term Contains clear and concise descriptions of the anatomical features relevant to each stage of development Large format for easy use Contains explanatory notes and legends, and more than 180 meticulously labeled plates, 1,300 photographs of individual histological sections, and 200 electron micrographs, illustrating: Intermittent serial histological sections through embryos throughout embryogenesis and organogenesis Differentiation of specific organs and organ systems, including the spinal cord, eyes, gonads, kidneys, lungs and skeletal system External appearance of intact embryos throughout development
Download or read book Postimplantation Development in the Mouse written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines the establishment of the germ layers and other cell lineages in the early embryo including details of cell movements during the beginning stages of primitive streak formation. Discusses patterns of gene expression during the development of such tissues as the limb bud, skeletal, muscle and the central nervous systems placing special emphasis on commitment to particular cell types. Although it concentrates on the mouse as an example of mammalian development--chick, amphibian and Drosophila embryogenesis are employed whenever these organisms are more applicable to the study of a particular problem.
Download or read book The Anatomical Basis of Mouse Development written by Matthew H. Kaufman and published by Academic Press. This book was released on 1999-03-10 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an essential anatomical resource for developmental biologists who need to know about any aspect of mouse developmental anatomy, as well as for geneticists using the mouse embryo as a model. The book is a companion to Kaufman's The Atlas of Mouse Development, and details the developmental anatomy of the early embryo, the transitional tissues, and all the major organ systems. It also provides extensive comparisons with human developmental anatomy, both normal and abnormal. The book has extensive reference indexes detailing developmental stage criteria. The Anatomical Basis of Mouse Development will be a key reference work for anyone who needs to understand developmental anatomy in normal and mutant mice. Complements Kaufman's The Atlas of Mouse Development Gives anatomical descriptions from oogenesis to birth, at a level of detail that goes beyond that found in most literature Provides detailed explanations for geneticists and molecular biologists with limited anatomical background to help them understand the emergence of all the major structures in the mouse embryo Contains comprehensive indexes detailing the appearance of over 1000 organs, tissues, and their components at different stages of mouse embryogenesis Includes comparisons with normal and abnormal human development Contains over 100 clear line diagrams showing mouse developmental anatomy as well as lineage relationships for the major organ systems
Download or read book The Mouse Its Reproduction and Development written by Roberts Rugh and published by . This book was released on 1968 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guide to Techniques in Mouse Development Part B written by Paul Wassarman and published by Academic Press. This book was released on 2010-09-24 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume comprehensively covers new technologies and methodologies that have appeared for the study of mouse development Update of volume 225, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993 Comprehensively covers: new techniques for the cryopreservation of gametes and embryos production of transgenic and null (knockout) animals (use of ES cells) generation of conditional/inducible mutant animals, use of gene-trap mutagenesis analysis of allele-specific expression, use of new reporter constructs humanizing of transgenic animals transcript profiling of mouse development imaging of mouse development rederivation of animals and use of mouse genomics
Download or read book Molecular Embryology of the Mouse Mutant Limb Deformity written by Laurie Lynn Jackson-Grusby and published by . This book was released on 1992 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Methods in Experimental Embryology of the Mouse written by Keen Alexander Rafferty and published by Johns Hopkins University Press. This book was released on 1970 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Anatomical Basis of Mouse Development written by Matthew H. Kaufman and published by Gulf Professional Publishing. This book was released on 1999-03-03 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Anatomical Basis of Mouse Development by Kaufman and Bard is an essential anatomical resource for developmental biologists needing to know about any aspect of mouse developmental anatomy, as well as for geneticists using the mouse embryo as a model. This book is a companion to Kaufman's The Atlas of Mouse Development and details the developmental anatomy of the early embryo, the transitional tissues, and all the major organ systems. It also includes extensive reference indexes detailing developmental stage criteria, when tissues first appear, and the constituent tissues of embryos at each of the 26 Theiler stages, as well as tissue and author indexes and a glossary. Key features: * Gives anatomical descriptions from oogenesis to birth at a level of detail that often goes beyond that found in the literature. * Provides detailed explanations for geneticists and molecular biologists with limited anatomical background to help them understand the emergence of all the major structures in the mouse embryo. * Contains comprehensive indexes detailing the appearance of over 1000 organs, tissues and their components at different stages of mouse embryogenesis, together with the Theiler developmental stages (1-26) at which each first appears. * Includes comparisons with normal and abnormal human development * Has over 100 clear line diagrams showing mouse developmental anatomy as well as lineage relationships for the major organ systems. This book will be a key reference work for anyone who needs to understand developmental anatomy in normal and mutant mice.
