Download or read book Molecular Endocrinology of Target Enzymes in Androgen Metabolism written by Torbjörn Söderström and published by . This book was released on 2001 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Metabolism of Anabolic Androgenic Steroids written by Victor A. Rogozkin and published by CRC Press. This book was released on 1991-06-14 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an authoritative review of the research regarding the influences of anabolic-androgenic steroids on metabolism. The book provides a concise description of the biochemistry of these steroids using simple terms and includes methods of separation and their clinical applications. The first section of the book examines the general structure, nomenclature, and classification of anabolic-androgenic steroids. Subsequent chapters explore concepts basic to understanding the pathways of their metabolism in both target and non-target tissues, including the interactions of steroids with receptors and the effects of steroids on the cellular metabolism of skeletal muscle. The changes and molecular base of modifications in metabolism during exercise involving anabolic-androgenic steroids are also described. Finally, a comprehensive review of methods for scanning and identifying anabolic-androgenic steroids in biological fluids is presented, as well as a discussion regarding the applicability and limitations of these techniques. The book provides valuable reference information for all scientists and clinicians engaged in sports medicine, exercise biochemistry, and endocrinology.
Download or read book Thyroid Hormone Metabolism written by Georg Hennemann and published by Marcel Dekker. This book was released on 1986 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Leydig Cell in Health and Disease written by Anita H. Payne and published by Springer Science & Business Media. This book was released on 2007-10-28 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive study of the Leydig cell, a fascinating and important cell type. It presents all of the developments in our understanding of Leydig cell biology and explores a wide variety of current and potential clinical applications. All aspects of Leydig cell biology, development, regulation, and physiology are explored in thirty-one expertly written chapters. This in-depth volume is an invaluable resource.
Download or read book Androgen Action written by Fahri Saatcioglu and published by Humana Press. This book was released on 2011-08-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Androgens play a critical role in the development and maintenance of the male reproductive system and affect important physiological processes and pathological conditions, including the homeostasis of the normal prostate and prostate cancer. Androgen Action: Methods and Protocols is designed to provide a tool box to study various phases of androgen action, from its entry to the cell to the phenotypic response that the cell mounts, with up-to-date techniques for biochemists, molecular biologists, cell biologists, geneticists, and pathologists. The volume opens with a brief review of the research history on androgen action and prostate carcinogenesis, followed by chapters that cover state-of-the-art methods to determine androgen levels in biological tissues and fluids, experimental procedures to study the various aspects of androgen receptor activity, and methodology to study salient examples of interactions between androgen signalling and other major signalling pathways in cells. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Androgen Action: Methods and Protocols provides a comprehensive overview of, and practical guidance on, the diverse methodologies that are propelling androgen action research forward, both for normal physiology as well as in disease states.
Download or read book Hyperandrogenism in Women written by R. Pasquali and published by Karger Medical and Scientific Publishers. This book was released on 2019-09-09 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyperandrogenism profoundly affects women’s lives from lowering self-esteem to changing cognition and affective motivation. The polycystic ovary syndrome (PCOS) is the most common androgen excess disorder worldwide. While it is not the focus of this book, some aspects are discussed. The aim of this book is to improve understanding of androgen excess and its impact on several conditions. Topics include development of adipose tissue in females, insulin sensitivity, congenital adrenal hyperplasia, and Cushing’s disease/syndrome. There is also a discussion of PCOS with emphasis on in utero origins and specific genetic and epigenetic factors. This book provides a wealth of relevant information for every endocrinologist and gynecologist who wants to broaden their knowledge of androgens in various conditions.
Download or read book Obesity and Gynecology written by Tahir A. Mahmood and published by Elsevier. This book was released on 2020-06-11 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity and Gynecology, Second Edition, presents updated chapters on a variety of topics, ranging from adolescent obesity, contraception, assisted reproduction and sexual dysfunction, to bariatric surgery and improving semen parameters. The prevalence of obesity in men and women continues to dramatically increase around the world. Obesity presents specific challenges in relation to male and female infertility and general gynecology. Patients who are obese require specific considerations and knowledge. - Presents an essential reference on the significant risks of obesity related to contraception, male and female infertility, and general gynecology - Builds foundational knowledge, showing how obesity relates to general gynecology, including menstrual disorders, breasts cancer, menopause and sexual dysfunction - Assembles critically evaluated chapters that focus on obesity and gynecology to meet the practical needs of gynecologists, endocrinologists and general practitioners
Download or read book Sex and Gender Factors Affecting Metabolic Homeostasis Diabetes and Obesity written by Franck Mauvais-Jarvis and published by Springer. This book was released on 2017-12-08 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.
Download or read book Endocrinology of the Testis and Male Reproduction written by Manuela Simoni and published by Springer. This book was released on 2017-09-18 with total page 1364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.
Download or read book Testosterone written by Susan Nieschlag and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: New developments in testosterone therapy are summarized here by internationally renowned experts. They review both basic and clinical knowledge in fourteen chapters. The book begins with the biochemistry of testosterone, its biosynthesis, metabolism and mechanisms of action in target organs. Three chapters deal with specific aspects of testosterone action, namely its role in spermatogenesis, its psychotropic effects and its effects on bones. Syndromes caused by androgen resistance are described in order to highlight the importance of properly functioning enzymes and receptors in the target organs. Causes and symptoms of male hypogonadism, the major indication for testosterone treatment, are described. Five chapters are devoted to the pharmacology, pharmacokinetics and clinical uses and abuses of testosterone preparations. The new transdermal testosterone application is described in detail. Side effects of testosterone treatment are reviewed. The possible role of androgens in the development of prostatic hypertrophy and carcinoma is discussed extensively since this question is of major concern to the clinician.
Download or read book The Leydig Cell written by Anita H. Payne and published by . This book was released on 1996 with total page 882 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles of Gender Specific Medicine written by Marianne Legato J and published by Academic Press. This book was released on 2009-10-29 with total page 797 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of gender-specific medicine examines how normal human biology and physiology differ between men and women and how the diagnosis and treatment of disease differs as a function of gender. This revealing research covers various conditions that predominantly occur in men as well conditions that predominantly occur in women. Among the areas of greatest difference are cardiovascular disease, mood disorders, the immune system, lung cancer as a consequence of smoking, osteoporosis, diabetes, obesity, and infectious diseases. The Second Edition of Principles of Gender-Specific Medicine focuses on the essentials of gender-specific medicine and the current study of sex and gender differences in human physiology and pathophysiology. New section editors, new chapter authors, and new chapters have been added to reflect the most up-to-date clinical research and practice. - Offers insight into how the gender-specific risks of one organ system's disease affects the health of other organ systems - Outlines the sex-specific differences of normal anatomy and physiology - Illustrates the gender-specific features and quantifies "gender" and "sex" as risk factors across all major diseases - Qualifies and analyzes the results of new drug therapies designed with gender-specific differences in mind: ex, hormone therapy in men and women for the prevention and treatment of cardiovascular disease - All chapters progress translationally from the basic science to the clinical applications of gender-specific therapies, drugs, or treatments - Sections on drug metabolism, aging, and meta-analysis of data incorporated into all disease-specific chapters
Download or read book Androgens in Gynecological Practice written by Leo Plouffe, Jr and published by Cambridge University Press. This book was released on 2015-06-25 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical approach to the field of androgen excess or deprivation in women's health. The content includes multiple viewpoints on the most common disorders in this class, such as polycystic ovary disease, hirsutism and menopausal issues. Each chapter provides a combination of long-lasting clinical principles in the diagnosis and management of these patients along with a state-of-the-art review. This text takes an innovative approach to uncommon conditions (such as congenital adrenal hyperplasia, transgender conditions). In addition to presenting clinical insights, and a review of the basic science underpinning these conditions, it focuses on key concepts that can be derived from these rare conditions to the entire field. This book is an essential addition to the library for any busy clinician who is looking for a practical reference guide but also for the sub-specialist who is looking for new and thought-provoking insights in this complex scientific area.
Download or read book Diagnosis and Management of Polycystic Ovary Syndrome written by NADIR R. FARID and published by Springer Science & Business Media. This book was released on 2009-02-27 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosis and Management of Polycystic Ovary Syndrome is a comprehensive clinical reference work for primary care physicians, internists, general endocrinologists, obstetricians, gynecologists and students. PCOS is a common but frequently misdiagnosed disease. Many symptoms can be alleviated by early intervention and effective management. Prominent endocrinologists are gathered to detail current research and treatment in this metabolic disorder, affecting a growing population. The chapters are comprehensive, providing cutting edge knowledge on pathogenesis, manifestations, diagnosis and treatment of PCOS. Each chapter will be concise concluding with cogent practice points. The variety of medical issues presenting in PCOS patients result in late referrals or in- appropriate advice. This title will be a tool in a further understanding of the metabolic and genetic basis of PCOS, while providing management strategies.
Download or read book Principles of Endocrinology and Hormone Action written by Antonino Belfiore and published by Springer. This book was released on 2018-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.
Download or read book Androgens in Health and Disease written by Carrie Bagatell and published by Springer Science & Business Media. This book was released on 2003-05-27 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authoritative researchers and clinicians review our latest understanding of andrology in both basic science and clinical medicine. Topics range from explaining the biology of androgens-from several different perspectives-to illuminating their role in the development and modulation of physiologic systems. Authors demonstrate in a number of cases that testosterone can be a useful adjunct to the treatment of a variety of disease states. Other chapters consider important topics such as androgens use in athletes, the potential of androgens to improve physical function and quality of life in older men, and androgens as potential male contraceptives.
Download or read book Endocrine Biomarkers written by Hossein Sadrzadeh and published by Elsevier. This book was released on 2017-09-25 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrine Biomarkers: Clinical Aspects and Laboratory Determination covers all the pre-analytical variables that can affect test results, both in the clinic and laboratory. Biomarkers of endocrine and bone diseases are discussed from both clinical and laboratory perspectives, and the authors elaborate on the teamwork-based app+roach between the clinician and the laboratory professional in the diagnosis and management of endocrine and bone disorders. Discussions include test utilization, laboratory measurement methods, harmonization and standardization, interpretation of results, and reference intervals. Each chapter ends with a discussion of one or two relevant cases with shared opinions from both a clinician and a clinical chemist. Each chapter also includes a summary box outlining key points and common pitfalls in the use of specific disease biomarkers and tests. - Focuses on the traditional, current, and emerging clinical chemistry tests for endocrine and bone diseases, along with their application in individual clinical management - Presents a brief discussion of each disorder and its respective interrelationships, along with laboratory methodologies that can be used to aid in evaluation of disorders - Reviews common approaches to the measurement of the relevant hormones, with a special focus on measures that require a structured clinical testing scenario - Reviews novel chemistry tests as potential means of future diagnostic tests - Provides an overview of the current methodology and controversies in the concept of target lipid levels, paying particular attention to the role of clinical chemistry in helping to implement population health targets
