Download or read book Molecular Biology Pathogenicity and Ecology of Bacterial Plasmids written by Stuart B. Levy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book resulted from presentations at an international conference on bacterial p1asmids held January 5-9, 1981 in Santo Domingo, Dominican Republic. This was the first meeting of its kind in the Southern Hemisphere. The meeting place was selected for its relaxed and comfortable climate, conducive to interactions among participants. More importantly the locale facilitated the participation of nearby Latin American clinical and research scientists who deal directly with the health manifestations of pathogenic p1asmids. Diseases and socio-economic practices of developing countries exist in the Dominican Republic whose scientific community could directly benefit from having the meeting there. The book includes the talks as well as extended abstracts of poster presentations from the meeting. This combination, which provides readers with reviews as well as recent findings, captures the full scientific exchange which took place during the 5-day meeting. As one indication of pathogenicity related to p1asmids, the conferees were surveyed for gastro-intestina1 problems during and after their stay in the Dominican Republic. The results are summarized at the end of this book.

Download or read book Molecular Biology Pathogenicity and Ecology of Bacterial Plasmids written by Stuart B Levy and published by . This book was released on 1981-08-01 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Biology of Plasmids written by David Summers and published by John Wiley & Sons. This book was released on 2009-07-17 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasmids are closed, circular pieces of DNA that are able to self-replicate and are carried by many bacteria. They provide unique functions for bacteria by allowing them to sexually replicate and to pass on genetic material between each other. Plasmids are also responsible for the genetic factors that give resistance to antibiotics, and provide the enzymes needed to break down poorly metabolised food resources. The author has provided an updated treatment of the structure, function and application of plasmids suitable for undergraduates and medical students. Employing an original teaching perspective--examining plasmids as living organisms with either a symbiotic or parasitic mode of survival--this text provides an important framework for understanding the structure and function of plasmids in an evolutionary context. The most up to date text on plasmids An innovative teaching perspective makes for easy student understanding Contains crucial chapters on the importance of plasmids for clinical and biological research

Download or read book Plasmids written by Kimber G. Hardy and published by IRL Press. This book was released on 1993 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This completely updated and revised second edition of Plasmids: A Practical Approach provides the researcher with detailed protocols for studying bacterial plasmids and for using plasmids and phagemids as vectors. With many new sections and protocols, it is the most up-to-date reference describing the techniques for the study of plasmid replication and maintenance, the fundamental methods for purifying plasmids and introducing them into cells, and the protocols for the mutagenesis and analysis of plasmid-encoded products. The book features further techniques for the study of plasmids and the use of plasmid vectors in such important groups of bacteria as animal and plant pathogens harboring virulence plasmids, Streptomyces, and lactococci. Plus, the book describes the use of plasmid composite vectors for expression of cDNA cloning, and much more. It is a invaluable reference for molecular biologists, microbiologists, and biotechnology researchers. It includes detailed protocols for studying bacterial plasmids and for using both plasmids and phagemids as vectors, techniques for studying fundamental aspects of plasmids, such as replication, are included, as well as methods for using plasmid vectors in important groups of bacteria. Also described are protocols for using phagemids, which are extremely useful tools for genetic engineering.

Download or read book Plasmids in Bacteria written by Donald R. Helinski and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Plasmids in Bacteria written by Donald R. Helinski and published by Springer. This book was released on 2012-12-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of bacterial plasmids has not always been as popular as it is today. For many years, the molecular biology of pro cary­ otes was focused heavily on bacteriophage and plasmid investigations which were carried out in only a few laboratories. Whatever inter­ est existed in plasmids concerned the role of these extrachromosomal elements in bacterial conjugation, genetic exchanges, and antibiotic resistance, as well as in the structure of plasmids themselves. Gradually, however, it became increasingly evident that many of the special characteristics displayed by bacteria of medical, agricul­ tural, industrial, and environmental importance are determined by genes carried by plasmids, and this interest in plasmid-encoded functions, such as bacterial virulence properties (exotoxin produc­ tion, serum resistance, adhesiveness), metabolism of organic com­ pounds, plant tumor formation, and biological nitrogen fixation, led to increasing study of. the plasmids that carry these genes. Inves­ tigations of other plasmid-related properties such as replication and recombination have yielded much information about fundamental biological processes; information having implications that extend far beyond the particular plasmids under study. Concurrently, plas­ mids were playing a key role in the discovery of bacterial transpos­ able elements and were proving to be increasingly useful in the elu­ cidation of mechanisms responsible for a variety of chromosomal rearrangement events in bacteria and plants. Their status as "mini­ chromosomes" that could be isolated easily from bacterial cells and then reintroduced into other cells by transformation is of fundamen­ tal importance in this regard.

Download or read book Bacteria Plasmids and Phages written by E. C. C. Lin and published by . This book was released on 1984 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bcateriology: an overview; Bacterial structure; Bacterial nutrition and metabolism; Growth of bacterial cultures; Gene expression and regulatory mechanisms; DNA replication and mutation bacteria; Genetic exchange between bacteria; Plasmids; General properties of bacterial viruses; Lytic development of phages; Lysogeny in temperature phages; DNA restriction and gene cloning; Chemotherrapy and antibiotics.

Download or read book Molecular Biology and Pathogenicity of Mycoplasmas written by Shmuel Razin and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: was the result of the efforts of Robert Cleverdon. The rapidly developing discipline of molecular biology and the rapidly expanding knowledge of the PPLO were brought together at this meeting. In addition to the PPLO specialists, the conference invited Julius Marmur to compare PPLO DNA to DNA of other organisms; David Garfinkel, who was one of the first to develop computer models of metabolism; Cyrus Levinthal to talk about coding; and Henry Quastler to discuss information theory constraints on very small cells. The conference was an announcement of the role of PPLO in the fundamental understanding of molecular biology. Looking back 40-some years to the Connecticut meeting, it was a rather bold enterprise. The meeting was international and inter-disciplinary and began a series of important collaborations with influences resonating down to the present. If I may be allowed a personal remark, it was where I first met Shmuel Razin, who has been a leading figure in the emerging mycoplasma research and a good friend. This present volume is in some ways the fulfillment of the promise of that early meeting. It is an example of the collaborative work of scientists in building an understanding of fundamental aspects of biology.

Download or read book Plant Pathogenic Bacteria written by Robert W. Jackson and published by Caister Academic Press Limited. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third chapter delves into the crucially understudied area of pathogen adaptation to the plant apoplast environment.

Download or read book Plasmid written by Munazza Gull and published by BoD – Books on Demand. This book was released on 2019-06-19 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book captures in a single volume the wealth of information on the plasmid structure, function, and biology of all organisms that have been examined to date. Plasmids exhibit wide variations in size, modes of replication and transmission, host ranges, and the genes they carry and have provided us with a great understanding of basic life principles at the molecular level. Written by experts in the field, this book is a valuable source of up-to-date information, delivering the latest impacts on studies in the areas of plasmid types, genomes, purification analysis, and expression of recombinant proteins in bacteria. Plasmid utilization in the synthesis of plasmid-based vaccines, plasmids as genetic tools, and their applications in ecology and the evolutionary process are also covered. This book is a single source of valuable information for instructors and students in advanced undergraduate and graduate courses on plasmids. It will also appeal to researchers seeking to find new relationships between biological processes that are linked by plasmids to the environment.

Download or read book Plasmids written by Marcelo E. Tolmasky and published by John Wiley & Sons. This book was released on 2020-07-24 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore the remarkable discoveries in the rapidly expanding field of plasmid biology Plasmids are integral to biological research as models for innumerable mechanisms of living cells, as tools for creating the most diverse therapies, and as crucial helpers for understanding the dissemination of microbial populations. Their role in virulence and antibiotic resistance, together with the generalization of "omics" disciplines, has recently ignited a new wave of interest in plasmids. This comprehensive book contains a series of expertly written chapters focused on plasmid biology, mechanistic details of plasmid function, and the increased utilization of plasmids in biotechnology and pharmacology that has occurred in the past decade. Plasmids: Biology and Impact in Biotechnology and Discovery serves as an invaluable reference for researchers in the wide range of fields and disciplines that utilize plasmids and can also be used as a textbook for upper-level undergraduate and graduate courses in biotechnology and molecular biology.

Download or read book Horizontal Gene Pool written by Christopher M. Thomas and published by CRC Press. This book was released on 2003-09-02 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteria are the most ubiquitous of all organisms. Responsible for a number of diseases and for many of the chemical cycles on which life depends, they are genetically adaptable. Vital to this adaptability is the existence of autonomous genetic elements-plasmids-which promote genetic exchange and recombination. The genes carried by any particular plasmid may be found in only a few individuals of any species but can also be shared with other species and thus constitute a horizontal gene pool. This book explains the various contributions that plasmids make to this pool: the replication, stable inheritance and transfer modules, the phenotypic markers they carry, the way they evolve, the ways they contribute to their host population and the approaches that we use to study and classify them. It also looks at what we know about their activity in natural communities and the way that they interact with other mobile elements to promote bacterial evolution.

Download or read book Bacterial Plasmids written by Kimber G. Hardy and published by . This book was released on 1986 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Bacteria Plasmids and Phages written by Edmund C. Lin and published by . This book was released on 1984 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Social Biology of Microbial Communities written by Institute of Medicine and published by National Academies Press. This book was released on 2013-01-10 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning with the germ theory of disease in the 19th century and extending through most of the 20th century, microbes were believed to live their lives as solitary, unicellular, disease-causing organisms . This perception stemmed from the focus of most investigators on organisms that could be grown in the laboratory as cellular monocultures, often dispersed in liquid, and under ambient conditions of temperature, lighting, and humidity. Most such inquiries were designed to identify microbial pathogens by satisfying Koch's postulates.3 This pathogen-centric approach to the study of microorganisms produced a metaphorical "war" against these microbial invaders waged with antibiotic therapies, while simultaneously obscuring the dynamic relationships that exist among and between host organisms and their associated microorganisms-only a tiny fraction of which act as pathogens. Despite their obvious importance, very little is actually known about the processes and factors that influence the assembly, function, and stability of microbial communities. Gaining this knowledge will require a seismic shift away from the study of individual microbes in isolation to inquiries into the nature of diverse and often complex microbial communities, the forces that shape them, and their relationships with other communities and organisms, including their multicellular hosts. On March 6 and 7, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats hosted a public workshop to explore the emerging science of the "social biology" of microbial communities. Workshop presentations and discussions embraced a wide spectrum of topics, experimental systems, and theoretical perspectives representative of the current, multifaceted exploration of the microbial frontier. Participants discussed ecological, evolutionary, and genetic factors contributing to the assembly, function, and stability of microbial communities; how microbial communities adapt and respond to environmental stimuli; theoretical and experimental approaches to advance this nascent field; and potential applications of knowledge gained from the study of microbial communities for the improvement of human, animal, plant, and ecosystem health and toward a deeper understanding of microbial diversity and evolution. The Social Biology of Microbial Communities: Workshop Summary further explains the happenings of the workshop.

Download or read book Ending the War Metaphor written by Institute of Medicine and published by National Academies Press. This book was released on 2006-07-09 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases have existed longer than us, as long as us, or are relatively newer than us. It may be the case that a disease has existed for many, many years but has only recently begun affecting humans. At the turn of the century the number of deaths caused by infections in the United States had been falling steadily but since the '80s has seen an increase. In the past 30 years alone 37 new pathogens have been identified as human disease threats and 12% of known human pathogens have been classified as either emerging or remerging. Whatever the story, there is currently a "war" on infectious diseases. This war is simply the systematic search for the microbial "cause" of each disease, followed by the development of antimicrobial therapies. The "war" on infectious diseases, however, must be revisited in order to develop a more realistic and detailed picture of the dynamic interactions among and between host organisms and their diverse populations of microbes. Only a fraction of these microbes are pathogens. Thus, in order to explore the crafting of a new metaphor for host-microbe relationships, and to consider how such a new perspective might inform and prioritize biomedical research, the Forum on Microbial Threats of the Institute of Medicine (IOM) convened the workshop, Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe Relationship on March 16-17, 2005. Workshop participants examined knowledge and approaches to learning about the bacterial inhabitants of the human gut, the best known host-microbe system, as well as findings from studies of microbial communities associated with other mammals, fish, plants, soil, and insects. The perspective adopted by this workshop is one that recognizes the breadth and diversity of host-microbe relationships beyond those relative few that result in overt disease. Included in this summary are the reports and papers of individuals participating in the Forum as well as the views of the editors.

Download or read book Gene Cloning written by David M. Glover and published by Springer. This book was released on 2013-12-19 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was originallyconceived in the form ofa second edition ofa volume published in 1980 in Chapman and Hall's 'OutllneStudies in Biology' series and entitled Genetic Engineering - Cloning DNA. It very rapidly became apparent that with the impact ofrecombinant DNA techniques being feIt in so many areas ofblology, it was going to be difficultifnotimpossible to keepthe bookwithin the space confines of these little monographs. The stays were therefore loosened and the book expanded comfortably to its present size. I hope that this extra space has allowed me to clarify sections ofthe text that were 'heavy going' in the earlierversion. Theextraspace has certainlyallowed me to cover topics that were not mentioned at all in the earlier book. These are primarily to be found in Chapters 7 and 8, which cover the rapid advances that have been recently made in the use ofplantand animal cells as hosts for recombinant DNAmolecules. The develop ment ofother vectors has certainly not stood still over the past four years. This has necessitated a thorough revision ofChapters 3 and 4, which deal with bacteriophage and bacterial plasmid vectors. Numerous techniques for in vitromutagenesis have now been tried and tested allowing me to givecomprehensive coverage ofthisarea in Chapter 2 along with the biochemical techniques used to construct recombinant DNA molecules. Readers with some background knowledge of the approaches to gene cloning will be able to go straight toapart ofthe book in whichthey are specificallyinterested.