Download or read book Molecular Aspects of Early Development written by George M. Malacinski and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: The early embryo has emerged as the focal point for analysis of the regulation of gene expression for several reasons. First, the fact that embryogenesis is under genetic control has been appreciated from the earliest days of classical embryology. When experimental techniques became available it was therefore logical that they should be applied to the embryo. With each new advance in methodology, interest in embryonic gene expression studies has increased. Second, many embryos offer unique opportunities for the investigation of specific aspects of the regulation of gene expression. Several phenomena--eg. , control of translation--can be very conveniently studied in a variety of marine invertebrate embryos. Those embryos contain large stores of maternally inherited mRNA which are translated in a highly ordered fashion during specific stages of post fertilization development. Marine invertebrate eggs can be conveniently artifically inseminated and labeled with radioactive precursors. Their analysis is leading to important insights into the mechanisms which regulate gene expression at post-transcriptional levels. Third, recent advances in both transmission and recombinant DNA genetics, especially in organisms such as Drosophila, are providing special opportunities for the analysis of regulatory mechanisms which operate at the level of the genome. Specific genes have been identified, isolated, and--in some instances--sequenced. The opportunity is now available to study the regulation of the expression of single genes in a vertical fashion--from the primary sequence of the gene to the tissues and organs which are the products of morphogenesis.
Download or read book Molecular Aspects of Early Development written by George M Malacinski and published by . This book was released on 1984-03-01 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Aspects of Early Development written by WH Klein (Ed) and published by . This book was released on 1984 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Transforming the Workforce for Children Birth Through Age 8 written by National Research Council and published by National Academies Press. This book was released on 2015-07-23 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children are already learning at birth, and they develop and learn at a rapid pace in their early years. This provides a critical foundation for lifelong progress, and the adults who provide for the care and the education of young children bear a great responsibility for their health, development, and learning. Despite the fact that they share the same objective - to nurture young children and secure their future success - the various practitioners who contribute to the care and the education of children from birth through age 8 are not acknowledged as a workforce unified by the common knowledge and competencies needed to do their jobs well. Transforming the Workforce for Children Birth Through Age 8 explores the science of child development, particularly looking at implications for the professionals who work with children. This report examines the current capacities and practices of the workforce, the settings in which they work, the policies and infrastructure that set qualifications and provide professional learning, and the government agencies and other funders who support and oversee these systems. This book then makes recommendations to improve the quality of professional practice and the practice environment for care and education professionals. These detailed recommendations create a blueprint for action that builds on a unifying foundation of child development and early learning, shared knowledge and competencies for care and education professionals, and principles for effective professional learning. Young children thrive and learn best when they have secure, positive relationships with adults who are knowledgeable about how to support their development and learning and are responsive to their individual progress. Transforming the Workforce for Children Birth Through Age 8 offers guidance on system changes to improve the quality of professional practice, specific actions to improve professional learning systems and workforce development, and research to continue to build the knowledge base in ways that will directly advance and inform future actions. The recommendations of this book provide an opportunity to improve the quality of the care and the education that children receive, and ultimately improve outcomes for children.
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biochemical and Molecular Basis of Pediatric Disease written by Edward C.C. Wong and published by Academic Press. This book was released on 2021-05-13 with total page 1172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical and Molecular Basis of Pediatric Disease, Fifth Edition has been a well-respected reference in the field for decades. This revision continues the strong focus on understanding the pathogenesis of pediatric disease, emphasizing not only the important role of the clinical laboratory in defining parameters that change with the disease process, but also the molecular basis of many pediatric diseases. Provides a fully-updated resource with more color illustrations Focuses on the biochemical and molecular basis of disease as well as the analytical techniques Defines important differences in the pathophysiology of diseases, comparing childhood with adult
Download or read book Molecular Insights Into Development In Humans Studies In Normal Development And Birth Defects written by Moyra Smith and published by World Scientific Publishing Company. This book was released on 2014-11-20 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim and scope of this book is to review current information on human development and processes of differentiation that have benefited from breakthrough analyses in stem cell biology, elucidation of genome and gene architecture and aspects of regulation of gene expression, analysis of signaling systems and transcription factor actions.Insights into actions of specific genes and their roles in development have been gathered through studies in patients with specific birth defects, including congenital malformations, metabolic defects and functional impairments.The book is organized into three sections, the first dealing with aspects of genomics, gene structure and regulation, analysis of signaling and function of specific organelles. The second section deals with molecular aspects of development of specific organs and structures such as, bone, face, brain, heart, liver, pancreas, kidney. The last section deals with specific malformations and tumors that provide insight into regulation of growth. Environmental factors that impact growth and development are also covered.
Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.
Download or read book Inborn Errors of Development written by Charles J. Epstein and published by Oxford University Press, USA. This book was released on 2004 with total page 1110 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, the clinical chapters are organized into sections by defined developmental pathways or gene families, and each section is preceded by a general overview. For each disorder the authors cover the disease-causing genes, the role of these genes in development as elucidated in model organisms, the human mutations that have been identified, and the developmental pathogenesis of the condition. Clinical descriptions, along with discussions of therapy and counseling, are provided. This book will be an invaluable resource for physicians, dentists, and other health professionals and for basic scientists interested in developmental processes and genetic perturbations that affect them.
Download or read book Gene Activity in Early Development written by Eric H. Davidson and published by . This book was released on 1986 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new third edition of Gene Activity in Early Development reflects the ten years of technological progress since the last edition. Providing a unique blend of classical and molecular knowledge, it discusses all major embryonic systems from both a comparative and mechanistic point of view. In deriving overall interpretations of developmental phenomena, it brings into play all the disparate forms of evidence, including genetic, molecular, and cytological.**This book is written for any serious student or scholar entering the field, whether his or her background is in genetics, molecular biology, or embryology.
Download or read book Cellular and Molecular Aspects of Developmental Biology written by M. Fougereau and published by North Holland. This book was released on 1986 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1956 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Methods in Developmental Biology written by Matt Guille and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: The process whereby a single cell, the fertilized egg, develops into an adult has fascinated for centuries. Great progress in understanding that process, h- ever, has been made in the last two decades, when the techniques of molecular biology have become available to developmental biologists. By applying these techniques, the exact nature of many of the interactions responsible for forming the body pattern are now being revealed in detail. Such studies are a large, and it seems ever-expanding, part of most life-science groups. It is at newcomers to this field that this book is primarily aimed. A number of different plants and animals serve as common model org- isms for developmental studies. In Molecular Methods in Developmental Bi- ogy: Xenopus and Zebrafish, a range of the molecular methods applicable to two of these organisms are described, these are the South African clawed frog, Xenopus laevis, and the zebrafish, Brachydanio rerio. The embryos of both of these species develop rapidly and externally, making them particularly suited to investigations of early vertebrate development. However, both Xenopus and zebrafish have their own advantages and disadvantages. Xenopus have large, robust embryos that can be manipulated surgically with ease, but their pseudotetraploidy and long generation time make them unsuitable candidates for genetics. This disadvantage may soon be overcome by using the diploid Xenopus tropicalis, and early experiments are already underway. The transp- ent embryos of zebrafish render them well-suited for in situ hybridization and immunohistochemistry, and good for observing mutations in genetic screens.
Download or read book Molecular and Cellular Mechanisms in Reproduction and Early Development written by Rafael A. Fissore and published by Frontiers Media SA. This book was released on 2019-08-20 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Research Topic aims to support progress towards understanding the different sets of developmental processes that are absolutely required to complete all the steps essential for successful embryonic development, under physiological conditions. We sought contributions that dealt with single cells, interaction between cells as well as intra- and extracellular signal transduction. The Research Topic presents original studies covering experimental and theoretical approaches, descriptions of new methodologies, reviews and opinions.
Download or read book Developmental Neurochemistry written by Richard Calvin Wiggins and published by . This book was released on 1985 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Aspects of Animal Development written by Rudolf Weber and published by Academic Press. This book was released on 2014-05-10 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biochemistry of Animal Development, Volume III: Molecular Aspects of Animal Development provides an account of the developments in the molecular approach to vertebrate development with particular emphasis on the functions of nucleic acids. The book discusses topics on oocyte maturation, transcriptional patterns in early development, the post-transcriptional control of gene expression, and the significance of gene amplification. Morphogenetic substances, growth-promoting proteins, and the functional differentiation of mitochondria in embryonic systems are covered as well. Biochemists, biologists, and zoologists will find the book invaluable.
Download or read book Cellular and Molecular Aspects of Fertilization and Early Embryonic Development written by Washington Academy of Sciences (Washington, D.C.) and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
