Download or read book Modularity of Pleiotropic Effects on Skeletal Morphology written by Jane P. Kenney-Hunt and published by . This book was released on 2007 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to understand the role of genetic variation in morphological evolution, it is important to understand the genetic architecture of morphological traits because different genetic architectures can have varied effects on evolutionary responses to selection and genetic drift. Aspects of genetic architecture include number and size of gene effects, dominance, epistasis, and pleiotropy.
Download or read book Morphological Integration written by Everett C. Olson and published by University of Chicago Press. This book was released on 1999-10 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite recent advances in genetics, development, anatomy, systematics, and morphometrics, the synthesis of ideas and research agenda put forth in the classic Morphological Integration remains remarkably fresh, timely, and relevant. Pioneers in reexamining morphology, Everett Olson and Robert Miller were among the first to explore the concept of the integrated organism in both living and extinct populations. In a new foreword and afterword, biologists Barry Chernoff and Paul Magwene summarize the landmark achievements made by Olson and Miller and bring matters discussed in the book up to date, suggest new methods, and accentuate the importance of continued research in morphological integration. Everett C. Olson was a professor at the University of Chicago and at the University of California, Los Angeles. He was a former president of the Society of Vertebrate Paleontology. Robert L. Miller was associate professor of geology at the University of Chicago, associate scientist in marine geology at the Woods Hole Oceanographic Institution, and a member of the board of editors of the Journal of Geology.
Download or read book Modularity in Development and Evolution written by Gerhard Schlosser and published by University of Chicago Press. This book was released on 2004-07 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modularity in Development and Evolution offers the first sustained exploration of modules from developmental and evolutionary perspectives. Contributors discuss what modularity is, how it can be identified and modeled, how it originated and evolved, and its biological significance. Covering modules at levels ranging from genes to colonies, the book focuses on their roles not just in structures but also in processes such as gene regulation. Among many exciting findings, the contributors demonstrate how modules can highlight key constraints on evolutionary processes. A timely synthesis of a crucial topic, Modularity in Development and Evolution shows the invaluable insights modules can give into both developmental complexities and their evolutionary origins.
Download or read book Bones and Cartilage written by Brian K. Hall and published by Academic Press. This book was released on 2014-12-23 with total page 911 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche
Download or read book Building Bones Bone Formation and Development in Anthropology written by Christopher J. Percival and published by Cambridge University Press. This book was released on 2017-02-23 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone is the tissue most frequently recovered archaeologically and is the material most commonly studied by biological anthropologists, who are interested in how skeletons change shape during growth and across evolutionary time. This volume brings together a range of contemporary studies of bone growth and development to highlight how cross-disciplinary research and new methods can enhance our anthropological understanding of skeletal variation. The novel use of imaging techniques from developmental biology, advanced sequencing methods from genetics, and perspectives from evolutionary developmental biology improve our ability to understand the bases of modern human and primate variation. Animal models can also be used to provide a broad biological perspective to the systematic study of humans. This volume is a testament to the drive of anthropologists to understand biological and evolutionary processes that underlie changes in bone morphology and illustrates the continued value of incorporating multiple perspectives within anthropological inquiry.
Download or read book Modularity in Development and Evolution written by Gerhard Schlosser and published by University of Chicago Press. This book was released on 2004-07 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modularity in Development and Evolution offers the first sustained exploration of modules from developmental and evolutionary perspectives. Contributors discuss what modularity is, how it can be identified and modeled, how it originated and evolved, and its biological significance. Covering modules at levels ranging from genes to colonies, the book focuses on their roles not just in structures but also in processes such as gene regulation. Among many exciting findings, the contributors demonstrate how modules can highlight key constraints on evolutionary processes. A timely synthesis of a crucial topic, Modularity in Development and Evolution shows the invaluable insights modules can give into both developmental complexities and their evolutionary origins.
Download or read book Population Genetics and Microevolutionary Theory written by Alan R. Templeton and published by John Wiley & Sons. This book was released on 2006-09-29 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links
Download or read book Epigenetics written by Benedikt Hallgrimsson Ph.D. and published by Univ of California Press. This book was released on 2011-04-11 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illuminating the processes and patterns that link genotype to phenotype, epigenetics seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene. With chapters written by leading authorities, this volume offers a broad integrative survey of epigenetics. Approaching this complex subject from a variety of perspectives, it presents a broad, historically grounded view that demonstrates the utility of this approach for understanding complex biological systems in development, disease, and evolution. Chapters cover such topics as morphogenesis and organ formation, conceptual foundations, and cell differentiation, and together demonstrate that the integration of epigenetics into mainstream developmental biology is essential for answering fundamental questions about how phenotypic traits are produced.
Download or read book Advances in Artificial Life written by Federico Moran and published by Springer Science & Business Media. This book was released on 1995-05-24 with total page 984 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains 71 revised refereed papers, including seven invited surveys, presented during the Third European Conference on Artificial Life, ECAL '95, held in Granada, Spain in June 1995. Originally AL was concerned with applying biologically inspired solutions to technology and with examining computational expertise in order to reproduce and understand life processes. Despite its short history, AL now is becoming a mature scientific field. The volume reports the state of the art in this exciting area of research; there are sections on foundations and epistemology, origins of life and evolution, adaptive and cognitive systems, artificial worlds, robotics and emulation of animal behavior, societies and collective behavior, biocomputing, and applications and common tools.
Download or read book Modularity written by Werner Callebaut and published by MIT Press. This book was released on 2005 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modularity—the attempt to understand systems as integrations of partially independent and interacting units—is today a dominant theme in the life sciences, cognitive science, and computer science. The concept goes back at least implicitly to the Scientific (or Copernican) Revolution, and can be found behind later theories of phrenology, physiology, and genetics; moreover, art, engineering, and mathematics rely on modular design principles. This collection broadens the scientific discussion of modularity by bringing together experts from a variety of disciplines, including artificial life, cognitive science, economics, evolutionary computation, developmental and evolutionary biology, linguistics, mathematics, morphology, paleontology, physics, theoretical chemistry, philosophy, and the arts. The contributors debate and compare the uses of modularity, discussing the different disciplinary contexts of "modular thinking" in general (including hierarchical organization, near-decomposability, quasi-independence, and recursion) or of more specialized concepts (including character complex, gene family, encapsulation, and mosaic evolution); what modules are, why and how they develop and evolve, and the implication for the research agenda in the disciplines involved; and how to bring about useful cross-disciplinary knowledge transfer on the topic. The book includes a foreword by the late Herbert A. Simon addressing the role of near-decomposability in understanding complex systems. Contributors: Lee Altenberg, Lauren W. Ancel-Meyers, Carl Anderson, Robert B. Brandon, Angela D. Buscalioni, Raffaele Calabretta, Werner Callebaut, Anne De Joan, Rafael Delgado-Buscalioni, Gunther J. Eble, Walter Fontana, Fernand Gobet, Alicia de la Iglesia, Slavik V. Jablan, Luigi Marengo, Daniel W. McShea, Jason Mezey, D. Kimbrough Oller, Domenico Parisi, Corrado Pasquali, Diego Rasskin-Gutman, Gerhard Schlosser, Herbert A. Simon, Roger D. K. Thomas, Marco Valente, Boris M. Velichkovsky, Gunter P. Wagner, Rasmus G. Winter Vienna Series in Theoretical Biology
Download or read book Evolutionary Genetics written by Charles W. Fox and published by Oxford University Press. This book was released on 2006-04-27 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Charles Fox and Jason Wolf have brought together leading researchers to produce a cutting-edge primer introducing readers to the major concepts in modern evolutionary genetics. This book spans the continuum of scale, from studies of DNA sequence evolution through proteins and development to multivariate phenotypic evolution, and the continuum of time, from ancient events that lead to current species diversity to the rapid evolution seen over relatively short time scales in experimental evolution studies. Chapters are accessible to an audience lacking extensive background in evolutionaryy genetics but also current and in-depth enough to be of value to established researchers in evolution biology.
Download or read book Philosophy of Biology written by and published by Elsevier. This book was released on 2007-02-05 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Philosophy of Biology is a rapidly expanding field. It is concerned with explanatory concepts in evolution, genetics, and ecology. This collection of 25 essays by leading researchers provides an overview of the state of the field. These essays are wholly new; none of them could have been written even ten years ago. They demonstrate how philosophical analysis has been able to contribute to sometimes contested areas of scientific theory making. -Written by internationally acknowledged leaders in the field- Entries make original contributions as well as summarizing state of the art discoveries in the field- Easy to read and understand
Download or read book The Shape of Life written by Rudolf A. Raff and published by University of Chicago Press. This book was released on 2012-12-14 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rudolf Raff is recognized as a pioneer in evolutionary developmental biology. In their 1983 book, Embryos, Genes, and Evolution, Raff and co-author Thomas Kaufman proposed a synthesis of developmental and evolutionary biology. In The Shape of Life, Raff analyzes the rise of this new experimental discipline and lays out new research questions, hypotheses, and approaches to guide its development. Raff uses the evolution of animal body plans to exemplify the interplay between developmental mechanisms and evolutionary patterns. Animal body plans emerged half a billion years ago. Evolution within these body plans during this span of time has resulted in the tremendous diversity of living animal forms. Raff argues for an integrated approach to the study of the intertwined roles of development and evolution involving phylogenetic, comparative, and functional biology. This new synthesis will interest not only scientists working in these areas, but also paleontologists, zoologists, morphologists, molecular biologists, and geneticists.
Download or read book Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease written by Roger N. Rosenberg and published by Elsevier. This book was released on 2014-10-28 with total page 1465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations
Download or read book Essential Concepts in Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2019-11-23 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
Download or read book Old Questions and Young Approaches to Animal Evolution written by José M. Martín-Durán and published by Springer. This book was released on 2019-07-22 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal evolution has always been at the core of Biology, but even today many fundamental questions remain open. The field of animal ‘evo-devo’ is leveraging recent technical and conceptual advances in development, paleontology, genomics and transcriptomics to propose radically different answers to traditional evolutionary controversies. This book is divided into four parts, each of which approaches animal evolution from a different perspective. The first part (chapters 2 and 3) investigates how new sources of evidence have changed conventional views of animal origins, while the second (chapters 4–8) addresses the connection between embryogenesis and evolution, and the genesis of cellular, tissue and morphological diversity. The third part (chapters 9 and 10) investigates how big data in molecular biology is transforming our understanding of the mechanisms governing morphological change in animals. In closing, the fourth part (chapters 11–13) explores new theoretical and conceptual approaches to animal evolution. ‘Old questions and young approaches to animal evolution’ offers a comprehensive and updated view of animal evolutionary biology that will serve both as a first step into this fascinating field for students and university educators, and as a review of complementary approaches for researchers.
Download or read book The Evolution of Senescence in the Tree of Life written by Richard P. Shefferson and published by Cambridge University Press. This book was released on 2017-02-23 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The existing theories on the evolution of senescence assume that senescence is inevitable in all organisms. However, recent studies have shown that this is not necessarily true. A better understanding of senescence and its underlying mechanisms could have far-reaching consequences for conservation and eco-evolutionary research. This book is the first to offer interdisciplinary perspectives on the evolution of senescence in many species, setting the stage for further developments. It brings together new insights from a wide range of scientific fields and cutting-edge research done on a multitude of different animals (including humans), plants and microbes, giving the reader a complete overview of recent developments and of the controversies currently surrounding the topic. Written by specialists from a variety of disciplines, this book is a valuable source of information for students and researchers interested in ageing and life history traits and populations.
