Download or read book Modern Trends in Toxicology written by and published by . This book was released on 1974 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Food Toxicology written by Ashish Sachan and published by CRC Press. This book was released on 2017-12-01 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers a selection of important research in the multifaceted field of food toxicology. With more than seven billion people in the world today and counting, advances in food toxicology have a direct bearing on food safety issues that are of concern to all humanity for the foreseeable future. Massive globalization, industrialization, and commercialization have affected every aspect of food production, the food supply chain, and food consumption. This informative volume offers the global perspectives of scientists in important areas related to biomarkers and nanosensors in food toxicology, toxicology of nanomaterials, chemicals in sanitation and packaging, additives, mycotoxins, endocrine disruptors, radionuclides, toxic metals, and waste-burning residues in food. The book also emphasizes regulatory toxicology and includes an interesting example case study. The challenge of sustainable and safe food for everyone needs a multidisciplinary and multi-sectorial approach from related industries and governments alike. Food chemical safety is an underappreciated aspect of consumer safety, and this volume seeks to help fill that gap by providing informative research for food scientists and researchers and many others.
Download or read book History of Modern Clinical Toxicology written by Alan Woolf and published by Academic Press. This book was released on 2021-10-13 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: History of Modern Clinical Toxicology describes the extraordinary advances in the practice of clinical toxicology within the past 70 years and brings together stories of the people – the champions of clinical toxicology - who contributed to these advances, discovered new therapies and antidotes, and made change happen. This book lays out the poison control system they built and the fascinating story of how they created a new and evolving medical specialty. With the participation of renowned international experts as authors, the book showcases the development of poison control centers around the world and the growth of the professional societies that represent and support them today. This book also tells the stories of the modern-day toxic disasters and recent toxic exposures that gained worldwide attention and notoriety. It outlines the public health responses to such calamities which have led to improvements in our understanding of the science and changes in public health policies and regulations to forestall future such events. Finally, the book covers key policies and agencies affecting poison control centers, addresses the challenges facing clinical toxicologists of today, and predicts advances and future innovations in the field. History of Modern Clinical Toxicology is a unique resource that provides the historical and international perspective that will help students, practitioners, scientists, and health policy makers put current issues and methods in perspective. It will help them understand how infrastructure and processes in clinical toxicology have evolved and why poison control systems are configured as they are. - Offers descriptions of the key regulatory advances affecting clinical toxicology - Provides synopses of modern-day poisoning disasters - Outlines the development of modern antidotes and future directions in clinical toxicology - Describes the origins and development of the U.S. poison control system - Includes the origins and features of professional clinical toxicology societies from around the world - Includes descriptions of the history of clinical toxicology and poison control in more than 35 countries
Download or read book New Frontiers in Environmental Toxicology written by Tanu Jindal and published by Springer Nature. This book was released on 2021-09-21 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides up-to-date information on toxic pollutants in the environment and their harmful effects on human health and nature. The book covers many important aspects of environmental toxicology, such as features, characterization, applications, environmental routes for dispersion, nanotoxicity, ecotoxicity and genotoxicity of nanomaterials, with emphasis on radiation toxicology, polar ecotoxicology, plastic toxicology, microbrial toxicology, nanotoxicology and pesticide toxicology. Also discussed is the use of microbes and nanotechnology for medicinal purposes, which has revealed important chemical prototypes in the discovery of new agents, stimulating the use of refined physical techniques and new syntheses of molecules with pharmaceutical applications for human welfare. The chapters also address the fate of nanoparticles in the environment, as well as nanotoxicology mechanisms impacting human health. The book will be of interest to toxicologists, environmental scientists, chemists, and students of microbiology, nanotechnology and pharmacology.
Download or read book Toxicity Testing in the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2007-10-05 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.
Download or read book Molecular Clinical and Environmental Toxicology written by Andreas Luch and published by Springer Science & Business Media. This book was released on 2012-06-07 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Toxicology is the third volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.
Download or read book Science and Judgment in Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 1994-01-01 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.
Download or read book Toxicology and Environmental Health Information Resources written by Institute of Medicine and published by National Academies Press. This book was released on 1997-02-10 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: The environment is increasingly recognized as having a powerful effect on human and ecological health, as well as on specific types of human morbidity, mortality, and disability. While the public relies heavily on federal and state regulatory agencies for protection from exposures to hazardous substances, it often looks to health professionals for information about routes of exposure and the nature and extent of associated adverse health consequences. However, most health professionals acquire only a minimal knowledge of toxicology during their education and training. In 1967 the National Library of Medicine (NLM) created an information resource, known today as the Toxicology and Environmental Health Information Program (TEHIP). In 1995 the NLM asked the Institute of Medicine to examine the accessiblity and utility of the TEHIP databases for the work of health professionals. This resulting volume contains chapters on TEHIP and other toxicology and environmental health databases, on understanding the toxicology and environmental health information needs of health professionals, on increasing awareness of information resources through training and outreach, on accessing and navigating the TEHIP databases, and on program issues and future directions.
Download or read book Recent Trends in Medicinal Plants Research written by Lie-Fen Shyur and published by Academic Press. This book was released on 2012-08-17 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants and other living organisms have great potential to treat human disease. There are two distinct types of biomedical research that seek to develop this potential. One type of research explores the value of medicinal plants as traditionally used and studies of these plants have the potential to determine which plants are most potent, optimize dosages and dose forms, and identify safety risks. Another type of research uses bioassays to identify single molecules from plants that have interesting bioactivities in isolation and might be useful lead compounds for the development of pharmaceutical drugs. This new volume of Advances in Botanical Research covers the recent trends in Medicinal Plants Research over 11 chapters. Topics that are covered include Development of Drugs from Plants - Regulation and Evaluation, Chinese Herbal Medicines for Rheumatoid Arthritis, and Taxol, camptothecin and beyond for cancer therapy. Covers the recent trends in medicinal plants research over 11 chapters Topics that are covered include Development of Drugs from Plants - Regulation and Evaluation, Chinese Herbal Medicines for Rheumatoid Arthritis, and Taxol, camptothecin and beyond for cancer therapy
Download or read book Toxicological Risk Assessment and Multi System Health Impacts from Exposure written by Aristidis M. Tsatsakis and published by Elsevier. This book was released on 2021-08-01 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. The book is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment. - Bridges basic research with clinical, epidemiological, regulatory, and translational research, conveying both an introductory understanding and the latest developments in the field - Evaluates real-life human health risk assessment for long-term exposures to xenobiotic mixtures and the role they play in contributing to chronic disease - Discusses advances in predictive (in silico) toxicology tools and the benefits of using omics technologies in toxicology research
Download or read book Green Toxicology written by Alexandra Maertens and published by Royal Society of Chemistry. This book was released on 2022-02-01 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green toxicology is an integral part of green chemistry. One of the key goals of green chemistry is to design less toxic chemicals. Therefore, an understanding of toxicology and hazard assessment is important for any chemist working in green chemistry, but toxicology is rarely part of most chemists' education. As a consequence, chemists lack the toxicological lens necessary to view chemicals in order to design safer substitutions. This book seeks to fill that gap and demonstrate how a basic understanding of toxicology, as well as the tools of in silico and in vitro toxicology, can be an integral part of green chemistry. R&D chemists, product stewards, and toxicologists who work in the field of sustainability, can all benefit from integrating green toxicology principles into their work. Topics include in silico tools for hazard assessment, toxicity testing, and lifecycle considerations, this book aims to act as a bridge between green toxicologists and green chemists.
Download or read book Modern Trends in Toxicology written by R. Goulding and published by . This book was released on 1968 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nonclinical Safety Assessment written by William J. Brock and published by John Wiley & Sons. This book was released on 2013-04-29 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonclinical Safety Assessment Nonclinical Safety Assessment A Guide to International Pharmaceutical Regulations Bringing a new drug to market is a costly time-consuming process. Increased regional and international regulation over the last twenty years, while necessary, has only served to amplify these costs. In response to this escalation, developmental strategies have shifted towards a more global approach. In order to create the most cost-effective and safe processes, it is critical for those bringing drugs to market to understand both the globally accepted regulations and the local variations. Nonclinical Safety Assessment: A Guide to International Pharmaceutical Regulations provides a practical description of nonclinical drug development regulations and requirements in the major market regions. It includes: ICH – the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use National regulations, including US FDA, Canada, Mercosur and Brazil, South Africa, China, Japan, India and Australia Repeated dose toxicity studies Carcinogenicity; Genotoxicity; Developmental and reproductive toxicology; Immunotoxicology Biotechnology-derived pharmaceuticals Vaccine development Phototoxicity and photocarcinogenicity Degradants, impurities, excipients and metabolites Primarily intended for those professionals actively involved in the nonclinical and clinical development of a pharmaceutical product, including toxicologists, pharmacologists, clinicians and project managers, this book provides a roadmap for successful new drug approval and marketing.
Download or read book Chemometrics and Cheminformatics in Aquatic Toxicology written by Kunal Roy and published by John Wiley & Sons. This book was released on 2022-01-06 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: CHEMOMETRICS AND CHEMINFORMATICS IN AQUATIC TOXICOLOGY Explore chemometric and cheminformatic techniques and tools in aquatic toxicology Chemometrics and Cheminformatics in Aquatic Toxicology delivers an exploration of the existing and emerging problems of contamination of the aquatic environment through various metal and organic pollutants, including industrial chemicals, pharmaceuticals, cosmetics, biocides, nanomaterials, pesticides, surfactants, dyes, and more. The book discusses different chemometric and cheminformatic tools for non-experts and their application to the analysis and modeling of toxicity data of chemicals to various aquatic organisms. You’ll learn about a variety of aquatic toxicity databases and chemometric software tools and webservers as well as practical examples of model development, including illustrations. You’ll also find case studies and literature reports to round out your understanding of the subject. Finally, you’ll learn about tools and protocols including machine learning, data mining, and QSAR and ligand-based chemical design methods. Readers will also benefit from the inclusion of: A thorough introduction to chemometric and cheminformatic tools and techniques, including machine learning and data mining An exploration of aquatic toxicity databases, chemometric software tools, and webservers Practical examples and case studies to highlight and illustrate the concepts contained within the book A concise treatment of chemometric and cheminformatic tools and their application to the analysis and modeling of toxicity data Perfect for researchers and students in chemistry and the environmental and pharmaceutical sciences, Chemometrics and Cheminformatics in Aquatic Toxicology will also earn a place in the libraries of professionals in the chemical industry and regulators whose work involves chemometrics.
Download or read book Molecular Clinical and Environmental Toxicology written by Andreas Luch and published by Springer Science & Business Media. This book was released on 2010-03-01 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Toxicology is the second volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.
Download or read book Fundamentals of Toxicology written by PK Gupta and published by Academic Press. This book was released on 2016-08-26 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty. - Explains the essential concepts of toxicology in a clear fashion - Provides in-depth coverage of testing protocols, common drugs, chemicals, and laboratory-based diagnostic and analytical toxicology - Explores the history, foundations, and most recent concepts of toxicology - Serves as an essential reference for advanced students in toxicology and across the biomedical, life, and environmental sciences who want to learn the concepts of toxicology
Download or read book Chelation Therapy in the Treatment of Metal Intoxication written by Jan Aaseth and published by Academic Press. This book was released on 2016-04-18 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chelation Therapy in the Treatment of Metal Intoxication presents a practical guide to the use of chelation therapy, from its basic chemistry, to available chelating antidotes, and the application of chelating agents. Several metals have long been known to be toxic to humans, and continue to pose great difficulty to treat. These challenges pose particular problems in industrial settings, with lead smelting known to be associated with hemopoietic alterations and paralyses, and the inhalation of mercury vapor in mercury mining being extremely detrimental to the central nervous system. Clinical experience has demonstrated that acute and chronic human intoxications with a range of metals can be treated efficiently by administration of chelating agents. Chelation Therapy in the Treatment of Metal Intoxication describes the chemical and biological principles of chelation in the treatment of these toxic metal compounds, including new chelators such as meso-2,3-dimercaptosuccinic acid (DMSA) and D,L-2,3-dimercapto-1-propanesulfonic acid (DMPS). - Presents all the current findings on the potential for chelation as a therapy for metal intoxication - Presents practical guidelines for selecting the most appropriate chelating agent - Includes coverage on radionuclide exposure and metal storage diseases - Describes the chemical and biological principles of chelation in the treatment of toxic metal compounds
