Download or read book Forces of Habit written by David T. Courtwright and published by . This book was released on 2001-03-23 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: What drives the drug trade, and how has it come to be what it is today? A global history of the acquisition of progressively more potent means of altering ordinary waking consciousness, this book is the first to provide the big picture of the discovery, interchange, and exploitation of the planet’s psychoactive resources, from tea and kola to opiates and amphetamines.
Download or read book Modern CNS Drug Discovery written by Rudy Schreiber and published by Springer Nature. This book was released on 2021-06-17 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of a new drug. Divided into four sections, the book starts by presenting a broad perspective on current approaches in central nervous system (CNS) drug discovery. The second section addresses the generation of ideas for the identification of targets and novel treatment strategies; covers core functions in early discovery, and provides an example of a novel treatment paradigm: brain stimulation. The third section highlights strategies and technologies in translational CNS drug discovery. In an effort to bridge the gap between discovery and clinical development, it also covers brain imaging, EEG and cognitive testing approaches. The fourth section extensively discusses the clinical phase of drug development, covering the basics of early clinical testing for psychopharmacological drugs. The book’s final chapter addresses the registration for newly developed drugs. Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments in drug discovery. Offering in-depth insights into the world of drug development, it represents essential reading for early researchers who want to prepare for a career in drug discovery in academia or industry.
Download or read book Generic written by Jeremy A. Greene and published by JHU Press. This book was released on 2014-10-27 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: The turbulent history of generic pharmaceuticals raises powerful questions about similarity and difference in modern medicine. Generic drugs are now familiar objects in clinics, drugstores, and households around the world. We like to think of these tablets, capsules, patches, and ointments as interchangeable with their brand-name counterparts: why pay more for the same? And yet they are not quite the same. They differ in price, in place of origin, in color, shape, and size, in the dyes, binders, fillers, and coatings used, and in a host of other ways. Claims of generic equivalence, as physician-historian Jeremy Greene reveals in this gripping narrative, are never based on being identical to the original drug in all respects, but in being the same in all ways that matter. How do we know what parts of a pill really matter? Decisions about which differences are significant and which are trivial in the world of therapeutics are not resolved by simple chemical or biological assays alone. As Greene reveals in this fascinating account, questions of therapeutic similarity and difference are also always questions of pharmacology and physiology, of economics and politics, of morality and belief. Generic is the first book to chronicle the social, political, and cultural history of generic drugs in America. It narrates the evolution of the generic drug industry from a set of mid-twentieth-century "schlock houses" and "counterfeiters" into an agile and surprisingly powerful set of multinational corporations in the early twenty-first century. The substitution of bioequivalent generic drugs for more expensive brand-name products is a rare success story in a field of failed attempts to deliver equivalent value in health care for a lower price. Greene’s history sheds light on the controversies shadowing the success of generics: problems with the generalizability of medical knowledge, the fragile role of science in public policy, and the increasing role of industry, marketing, and consumer logics in late-twentieth-century and early twenty-first century health care.
Download or read book Drugs on the Page written by Matthew James Crawford and published by University of Pittsburgh Press. This book was released on 2019-05-15 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the early modern Atlantic World, pharmacopoeias—official lists of medicaments and medicinal preparations published by municipal, national, or imperial governments—organized the world of healing goods, giving rise to new and valuable medical commodities such as cinchona bark, guaiacum, and ipecac. Pharmacopoeias and related texts, developed by governments and official medical bodies as a means to standardize therapeutic practice, were particularly important to scientific and colonial enterprises. They served, in part, as tools for making sense of encounters with a diversity of peoples, places, and things provoked by the commercial and colonial expansion of early modern Europe. Drugs on the Page explores practices of recording, organizing, and transmitting information about medicinal substances by artisans, colonial officials, indigenous peoples, and others who, unlike European pharmacists and physicians, rarely had a recognized role in the production of official texts and medicines. Drawing on examples across various national and imperial contexts, contributors to this volume offer new and valuable insights into the entangled histories of knowledge resulting from interactions and negotiations between Europeans, Africans, and Native Americans from 1500 to 1850.
Download or read book Medicating Modern America written by Andrea Tone and published by NYU Press. This book was released on 2007-01-08 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: With Americans paying more than $200 billion each year for prescription pills, the pharmaceutical business is the most profitable in the nation. The popularity of prescription drugs in recent decades has remade the doctor/patient relationship, instituting prescription-writing and pill-taking as an integral part of medical practice and everyday life. Medicating Modern America examines the meanings behind this pharmaceutical revolution through the interconnected histories of eight of the most influential and important drugs: antibiotics, mood stabilizers, hormone replacement therapy, oral contraceptives, tranquilizers, stimulants, statins, and Viagra. All of these drugs have been popular, profitable, influential, and controversial, and the authors take a historical approach to studying their development, prescription, and consumption. This perspective locates the histories of prescription medicines in specific cultural contexts while revealing the extent to which contemporary debates about pharmaceutical drugs echo concerns voiced by Americans in the past. Exploring the rich and multi-faceted history of pharmaceutical drugs in the United States, Medicating Modern America unveils the untold stories behind America's pharmaceutical obsession. Contributors include: Robert Bud, Jennifer R. Fishman, Jeremy A. Greene, David Healy, Suzanne White Junod, Ilina Singh, Andrea Tone, and Elizabeth Siegel Watkins.
Download or read book Ten Drugs written by Thomas Hager and published by Abrams. This book was released on 2019-03-05 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: “The stories are skillfully told and entirely entertaining . . . An expert, mostly feel-good book about modern medicine” from the award-winning author (Kirkus Reviews, starred review). Behind every landmark drug is a story. It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine. Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book. “[An] absorbing new book.” —The New York Times Book Review “[A] well-written and engaging chronicle.” —The Wall Street Journal “Lucidly informative and compulsively readable.” —Publishers Weekly “Entertaining [and] insightful.” —Booklist “Well-written, well-researched and fascinating to read Ten Drugs provides an insightful look at how drugs have shaped modern medical practices. Towards the end of the book Hager writes that he ‘came away surprised by some of the things he had learned.’ I had the very same reaction.” —Penny Le Couteur, coauthor of Napoleon’s Buttons: How 17 Molecules Changed History
Download or read book National Drug Code Directory written by and published by . This book was released on 1982 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Modern Phytomedicine written by Iqbal Ahmad and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely and original handbook paves the way to success in plant-based drug development, systematically addressing the issues facing a pharmaceutical scientist who wants to turn a plant compound into a safe and effective drug. Plant pharmacologists from around the world demonstrate the potentials and pitfalls involved, with many of the studies and experiments reported here published for the first time. The result is a valuable source of information unavailable elsewhere.
Download or read book The Evolution of Drug Discovery written by Enrique Ravina and published by John Wiley & Sons. This book was released on 2011-04-18 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Der Band zeichnet die oft spektakulären Erfolgs- oder Misserfolgsgeschichten neuartiger pharmazeutischer Wirkstoffe nach und nimmt den Leser dabei mit auf die Reise von den ersten Anfängen der Heilkunde bis zum Milliardengeschäft der modernen Pharmaindustrie. Sachkundig geschrieben, reich illustriert, anregend: Eine unterhaltsame Lektüre!
Download or read book A History of Alcohol and Drugs in Modern South Asia written by Harald Fischer-Tiné and published by Routledge. This book was released on 2014-01-03 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the beginning of the 21st century, alcoholism, transnational drug trafficking and drug addiction constitute major problems in various South Asian countries. The production, circulation and consumption of intoxicating substances created (and responded to) social upheavals in the region and had widespread economic, political and cultural repercussions on an international level. This book looks at the cultural, social, and economic history of intoxicants in South Asia, and analyses the role that alcohol and drugs have played in the region. The book explores the linkages between changing meanings of intoxicating substances, the making of and contestations over colonial and national regimes of regulation, economics, and practices and experiences of consumption. It shows the development of current meanings of intoxicants in South Asia – in terms of politics, cultural norms and identity formation – and the way in which the history of drugs and alcohol is enmeshed in the history of modern empires and nation states — even in a country in which a staunch teetotaller and active anti-drug crusader like Mohandas Gandhi is presented as the ‘father of the nation’. Primarily a historical analysis, the book also includes perspectives from Modern Indology and Cultural Anthropology and situates developments in South Asia in wider imperial and global contexts. It is of interest to scholars working on the social and cultural history of alcohol and drugs, South Asian Studies and Global History.
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book Modern Pharmaceutics written by Gilbert S. Banker and published by . This book was released on 1979 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drugs Behavior and Modern Society written by Charles F. Levinthal and published by Allyn & Bacon. This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides an introduction to the basic facts and major issues concerning drug-taking behavior. In today's world, drugs and their use present a social paradox, combining the potential for good and for bad. As a society and as individuals, we can be the beneficiaries of drugs or their victims.
Download or read book On Depression written by S. Nassir Ghaemi and published by JHU Press. This book was released on 2013-07-01 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lasting happiness comes not from chasing the American dream but from living an authentic life—which includes despair. In a culture obsessed with youth, financial success, and achieving happiness, is it possible to live an authentic, meaningful life? Nassir Ghaemi, director of the Mood Disorder Program at Tufts Medical Center, reflects on our society's current quest for happiness and rejection of any emotion resembling sadness. On Depression asks readers to consider the benefits of despair and the foibles of an unexamined life. Too often depression as disease is mistreated or not treated at all. Ghaemi warns against the "pretenders" who confuse our understanding of depression—both those who deny disease and those who use psychiatric diagnosis "pragmatically" or unscientifically. But experiencing sadness, even depression, can also have benefits. Ghaemi asserts that we can create a "narrative of ourselves such that we know and accept who we are," leading to a deeper, lasting level of contentment and a more satisfying personal and public life. Depression is complex, and we need guides to help us understand it, guides who comprehend it existentially as part of normal human experience and clinically as sometimes needing the right kind of treatment, including medications. Ghaemi discusses these guides in detail, thinkers like Viktor Frankl, Rollo May, Karl Jaspers, and Leston Havens, among others. On Depression combines examples from philosophy and the history of medicine with psychiatric principles informed by the author's clinical experience with people who struggle with mental illness. He has seen great achievements arise from great suffering and feels that understanding depression can provide important insights into happiness.
Download or read book Medical Monopoly written by Joseph M. Gabriel and published by University of Chicago Press. This book was released on 2014-10-24 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: During most of the nineteenth century, physicians and pharmacists alike considered medical patenting and the use of trademarks by drug manufacturers unethical forms of monopoly; physicians who prescribed patented drugs could be, and were, ostracized from the medical community. In the decades following the Civil War, however, complex changes in patent and trademark law intersected with the changing sensibilities of both physicians and pharmacists to make intellectual property rights in drug manufacturing scientifically and ethically legitimate. By World War I, patented and trademarked drugs had become essential to the practice of good medicine, aiding in the rise of the American pharmaceutical industry and forever altering the course of medicine. Drawing on a wealth of previously unused archival material, Medical Monopoly combines legal, medical, and business history to offer a sweeping new interpretation of the origins of the complex and often troubling relationship between the pharmaceutical industry and medical practice today. Joseph M. Gabriel provides the first detailed history of patent and trademark law as it relates to the nineteenth-century pharmaceutical industry as well as a unique interpretation of medical ethics, therapeutic reform, and the efforts to regulate the market in pharmaceuticals before World War I. His book will be of interest not only to historians of medicine and science and intellectual property scholars but also to anyone following contemporary debates about the pharmaceutical industry, the patenting of scientific discoveries, and the role of advertising in the marketplace.
Download or read book A Medicated Empire written by Timothy M. Yang and published by Cornell University Press. This book was released on 2021-06-15 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: In A Medicated Empire, Timothy M. Yang explores the history of Japan's pharmaceutical industry in the early twentieth century through a close account of Hoshi Pharmaceuticals, one of East Asia's most influential drug companies from the late 1910s through the early 1950s. Focusing on Hoshi's connections to Japan's emerging nation-state and empire, and on the ways in which it embraced an ideology of modern medicine as a humanitarian endeavor for greater social good, Yang shows how the industry promoted a hygienic, middle-class culture that was part of Japan's national development and imperial expansion. Yang makes clear that the company's fortunes had less to do with scientific breakthroughs and medical innovations than with Japan's web of social, political, and economic relations. He lays bare Hoshi's business strategies and its connections with politicians and bureaucrats, and he describes how public health authorities dismissed many of its products as placebos at best and poisons at worst. Hoshi, like other pharmaceutical companies of the time, depended on resources and markets opened up, often violently, through colonization. Combining global histories of business, medicine, and imperialism, A Medicated Empire shows how the development of the pharmaceutical industry simultaneously supported and subverted regimes of public health at home and abroad.
Download or read book Elemene Antitumor Drugs written by Tian Xie and published by Elsevier. This book was released on 2022-12-02 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Elemene Antitumor Drugs: Molecular Compatibility Theory and its Applications in New Drug Development and Clinical Practice introduces natural anti-tumor drug elemene and systematic basic and clinical research. Basic principles of the compatibility theory of traditional Chinese medicine and the research and development process of the natural anti-tumor drug elemene under the guidance of this principle are introduced. In addition, the traditional extraction and separation of elemene and the new biosynthesis technology developed by the author's team are described. Then, the systematic anti-tumor mechanism research of elemene are introduced, including unique multi-target and comprehensive anti-tumor mechanisms and detailed mechanisms for treating specific tumors. Under the guidance of compatibility theory, clinical research on the combined application of elemene and different chemotherapeutic drugs has been further carried out, achieving positive results in clinical practice. Finally, the book also introduces the research and exploration of new drug delivery systems of elemene, as well as the structural modification and drug discovery progress taking elemene structure as the lead compound. - Systematically introduces the principles of molecular compatibility theory and its application in new drug development and clinical practice - Provides comprehensive information on drug development, drug preparation, mechanism study and clinical research of the natural antitumor drug elemene - Includes valuable experience in drug development and related industry chain construction based on natural products - Introduces clinical research ideas and experiences for expanding clinical indications - Presents the practical methods and research experience of the secondary development of traditional Chinese medicine
