Download or read book Biopharmaceutics Modeling and Simulations written by Kiyohiko Sugano and published by John Wiley & Sons. This book was released on 2012-07-31 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive introduction to using modeling and simulation programs in drug discovery and development Biopharmaceutical modeling has become integral to the design and development of new drugs. Influencing key aspects of the development process, including drug substance design, formulation design, and toxicological exposure assessment, biopharmaceutical modeling is now seen as the linchpin to a drug's future success. And while there are a number of commercially available software programs for drug modeling, there has not been a single resource guiding pharmaceutical professionals to the actual tools and practices needed to design and test safe drugs. A guide to the basics of modeling and simulation programs, Biopharmaceutics Modeling and Simulations offers pharmaceutical scientists the keys to understanding how they work and are applied in creating drugs with desired medicinal properties. Beginning with a focus on the oral absorption of drugs, the book discusses: The central dogma of oral drug absorption (the interplay of dissolution, solubility, and permeability of a drug), which forms the basis of the biopharmaceutical classification system (BCS) The concept of drug concentration How to simulate key drug absorption processes The physiological and drug property data used for biopharmaceutical modeling Reliable practices for reporting results With over 200 figures and illustrations and a peerless examination of all the key aspects of drug research—including running and interpreting models, validation, and compound and formulation selection—this reference seamlessly brings together the proven practical approaches essential to developing the safe and effective medicines of tomorrow.

Download or read book Simulation Modelling Practice and Theory written by Evon M. O. Abu-Taieh and published by Intechopen. This book was released on 2019 with total page 83 pages. Available in PDF, EPUB and Kindle. Book excerpt: The influx of data in the world today needs analysis that no one method can handle. Some reports estimated the influx of data would reach 163 zitabytes by 2025, hence the need for simulation and modeling theory and practice. Simulation and modeling tools and techniques are most important in this day and age. While simulation carries the needed work, tools for visualizing the results help in the decision-making process. Simulation ranges from a simple queue to molecular dynamics, including seismic reliability analysis, structural integrity assessment, games, reliability engineering, and system safety. This book will introduce practitioners, researchers, and novice users to simulation and modeling, and to the world of imagination.

Download or read book Process Modeling and Simulation for Chemical Engineers written by Simant R. Upreti and published by John Wiley & Sons. This book was released on 2017-05-01 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a rigorous treatment of the fundamental concepts and techniques involved in process modeling and simulation. The book allows the reader to: (i) Get a solid grasp of “under-the-hood” mathematical results (ii) Develop models of sophisticated processes (iii) Transform models to different geometries and domains as appropriate (iv) Utilize various model simplification techniques (v) Learn simple and effective computational methods for model simulation (vi) Intensify the effectiveness of their research Modeling and Simulation for Chemical Engineers: Theory and Practice begins with an introduction to the terminology of process modeling and simulation. Chapters 2 and 3 cover fundamental and constitutive relations, while Chapter 4 on model formulation builds on these relations. Chapters 5 and 6 introduce the advanced techniques of model transformation and simplification. Chapter 7 deals with model simulation, and the final chapter reviews important mathematical concepts. Presented in a methodical, systematic way, this book is suitable as a self-study guide or as a graduate reference, and includes examples, schematics and diagrams to enrich understanding. End of chapter problems with solutions and computer software available online at www.wiley.com/go/upreti/pms_for_chemical_engineers are designed to further stimulate readers to apply the newly learned concepts.

Download or read book Mosfet Modeling For Vlsi Simulation Theory And Practice written by Narain Arora and published by World Scientific. This book was released on 2007-02-14 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reprint of the classic text, this book popularized compact modeling of electronic and semiconductor devices and components for college and graduate-school classrooms, and manufacturing engineering, over a decade ago. The first comprehensive book on MOS transistor compact modeling, it was the most cited among similar books in the area and remains the most frequently cited today. The coverage is device-physics based and continues to be relevant to the latest advances in MOS transistor modeling. This is also the only book that discusses in detail how to measure device model parameters required for circuit simulations.The book deals with the MOS Field Effect Transistor (MOSFET) models that are derived from basic semiconductor theory. Various models are developed, ranging from simple to more sophisticated models that take into account new physical effects observed in submicron transistors used in today's (1993) MOS VLSI technology. The assumptions used to arrive at the models are emphasized so that the accuracy of the models in describing the device characteristics are clearly understood. Due to the importance of designing reliable circuits, device reliability models are also covered. Understanding these models is essential when designing circuits for state-of-the-art MOS ICs.

Download or read book Smart Modeling and Simulation for Complex Systems written by Quan Bai and published by Springer. This book was released on 2015-01-10 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide a description of these new Artificial Intelligence technologies and approaches to the modeling and simulation of complex systems, as well as an overview of the latest scientific efforts in this field such as the platforms and/or the software tools for smart modeling and simulating complex systems. These tasks are difficult to accomplish using traditional computational approaches due to the complex relationships of components and distributed features of resources, as well as the dynamic work environments. In order to effectively model the complex systems, intelligent technologies such as multi-agent systems and smart grids are employed to model and simulate the complex systems in the areas of ecosystem, social and economic organization, web-based grid service, transportation systems, power systems and evacuation systems.

Download or read book Emerging Technologies for Health and Medicine written by Dac-Nhuong Le and published by John Wiley & Sons. This book was released on 2018-10-16 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Showcases the latest trends in new virtual/augmented reality healthcare and medical applications and provides an overview of the economic, psychological, educational and organizational impacts of these new applications and how we work, teach, learn and provide care. With the current advances in technology innovation, the field of medicine and healthcare is rapidly expanding and, as a result, many different areas of human health diagnostics, treatment and care are emerging. Wireless technology is getting faster and 5G mobile technology allows the Internet of Medical Things (IoMT) to greatly improve patient care and more effectively prevent illness from developing. This book provides an overview and review of the current and anticipated changes in medicine and healthcare due to new technologies and faster communication between users and devices. The groundbreaking book presents state-of-the-art chapters on many subjects including: A review of the implications of Virtual Reality (VR) and Augmented Reality (AR) healthcare applications A review of current augmenting dental care An overview of typical human-computer interaction (HCI) that can help inform the development of user interface designs and novel ways to evaluate human behavior to responses in VR and other new technologies A review of telemedicine technologies Building empathy in young children using augmented reality AI technologies for mobile health of stroke monitoring & rehabilitation robotics control Mobile doctor brain AI App An artificial intelligence mobile cloud computing tool Development of a robotic teaching aid for disabled children Training system design of lower limb rehabilitation robot based on virtual reality

Download or read book Discrete and Continuous Simulation written by Susmita Bandyopadhyay and published by CRC Press. This book was released on 2014-06-25 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: When it comes to discovering glitches inherent in complex systems-be it a railway or banking, chemical production, medical, manufacturing, or inventory control system-developing a simulation of a system can identify problems with less time, effort, and disruption than it would take to employ the original. Advantageous to both academic and industria

Download or read book Modeling and Simulation Fundamentals written by John A. Sokolowski and published by John Wiley & Sons. This book was released on 2010-07-13 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: An insightful presentation of the key concepts, paradigms, and applications of modeling and simulation Modeling and simulation has become an integral part of research and development across many fields of study, having evolved from a tool to a discipline in less than two decades. Modeling and Simulation Fundamentals offers a comprehensive and authoritative treatment of the topic and includes definitions, paradigms, and applications to equip readers with the skills needed to work successfully as developers and users of modeling and simulation. Featuring contributions written by leading experts in the field, the book's fluid presentation builds from topic to topic and provides the foundation and theoretical underpinnings of modeling and simulation. First, an introduction to the topic is presented, including related terminology, examples of model development, and various domains of modeling and simulation. Subsequent chapters develop the necessary mathematical background needed to understand modeling and simulation topics, model types, and the importance of visualization. In addition, Monte Carlo simulation, continuous simulation, and discrete event simulation are thoroughly discussed, all of which are significant to a complete understanding of modeling and simulation. The book also features chapters that outline sophisticated methodologies, verification and validation, and the importance of interoperability. A related FTP site features color representations of the book's numerous figures. Modeling and Simulation Fundamentals encompasses a comprehensive study of the discipline and is an excellent book for modeling and simulation courses at the upper-undergraduate and graduate levels. It is also a valuable reference for researchers and practitioners in the fields of computational statistics, engineering, and computer science who use statistical modeling techniques.

Download or read book Circuit Simulation with SPICE OPUS written by Tadej Tuma and published by Springer Science & Business Media. This book was released on 2009-06-23 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a unique combination of a basic guide to general analog circuit simulation and a SPICE OPUS software manual, which may be used as a textbook or self-study reference. The book is divided into three parts: mathematical theory of circuit analysis, a crash course on SPICE OPUS, and a complete SPICE OPUS reference guide. All simulations as well as the free simulator software may be directly downloaded from the SPICE OPUS homepage: www.spiceopus.si. Circuit Simulation with SPICE OPUS is intended for a wide audience of undergraduate and graduate students, researchers, and practitioners in electrical and systems engineering, circuit design, and simulation development.

Download or read book AnyLogic 7 in Three Days written by Ilya Grigoryev and published by . This book was released on 2015-03-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE NEW EDITION OF THE BOOK, COMPLETELY UP-TO-DATE (FOR ANYLOGIC 8.3.2) IS AVAILABLE HERE: https://www.amazon.com/AnyLogic-Three-Days-Simulation-Modeling-ebook/dp/B07FYP8Y3C

Download or read book Handbook of Simulation written by Jerry Banks and published by John Wiley & Sons. This book was released on 1998-09-14 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dieses Buch ist eine unschätzbare Informationsquelle für alle Ingenieure, Designer, Manager und Techniker bei Entwicklung, Studium und Anwendung einer großen Vielzahl von Simulationstechniken. Es vereint die Arbeit internationaler Simulationsexperten aus Industrie und Forschung. Alle Aspekte der Simulation werden in diesem umfangreichen Nachschlagewerk abgedeckt. Der Leser wird vertraut gemacht mit den verschiedenen Techniken von Industriesimulationen sowie mit Einsatz, Anwendungen und Entwicklungen. Neueste Fortschritte wie z.B. objektorientierte Programmierung werden ebenso behandelt wie Richtlinien für den erfolgreichen Umgang mit simulationsgestützten Prozessen. Auch gibt es eine Liste mit den wichtigsten Vertriebs- und Zulieferadressen. (10/98)

Download or read book Modeling and Simulation of Discrete Event Systems written by Byoung Kyu Choi and published by John Wiley & Sons. This book was released on 2013-08-07 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer modeling and simulation (M&S) allows engineers to study and analyze complex systems. Discrete-event system (DES)-M&S is used in modern management, industrial engineering, computer science, and the military. As computer speeds and memory capacity increase, so DES-M&S tools become more powerful and more widely used in solving real-life problems. Based on over 20 years of evolution within a classroom environment, as well as on decades-long experience in developing simulation-based solutions for high-tech industries, Modeling and Simulation of Discrete-Event Systems is the only book on DES-M&S in which all the major DES modeling formalisms – activity-based, process-oriented, state-based, and event-based – are covered in a unified manner: A well-defined procedure for building a formal model in the form of event graph, ACD, or state graph Diverse types of modeling templates and examples that can be used as building blocks for a complex, real-life model A systematic, easy-to-follow procedure combined with sample C# codes for developing simulators in various modeling formalisms Simple tutorials as well as sample model files for using popular off-the-shelf simulators such as SIGMA®, ACE®, and Arena® Up-to-date research results as well as research issues and directions in DES-M&S Modeling and Simulation of Discrete-Event Systems is an ideal textbook for undergraduate and graduate students of simulation/industrial engineering and computer science, as well as for simulation practitioners and researchers.

Download or read book An Introduction to Network Modeling and Simulation for the Practicing Engineer written by Jack L. Burbank and published by John Wiley & Sons. This book was released on 2011-08-04 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the practicing engineer with a concise listing of commercial and open-source modeling and simulation tools currently available including examples of implementing those tools for solving specific Modeling and Simulation examples. Instead of focusing on the underlying theory of Modeling and Simulation and fundamental building blocks for custom simulations, this book compares platforms used in practice, and gives rules enabling the practicing engineer to utilize available Modeling and Simulation tools. This book will contain insights regarding common pitfalls in network Modeling and Simulation and practical methods for working engineers.

Download or read book Simulation Modeling and Arena written by Manuel D. Rossetti and published by John Wiley & Sons. This book was released on 2015-05-26 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizes a hands-on approach to learning statistical analysis and model building through the use of comprehensive examples, problems sets, and software applications With a unique blend of theory and applications, Simulation Modeling and Arena®, Second Edition integrates coverage of statistical analysis and model building to emphasize the importance of both topics in simulation. Featuring introductory coverage on how simulation works and why it matters, the Second Edition expands coverage on static simulation and the applications of spreadsheets to perform simulation. The new edition also introduces the use of the open source statistical package, R, for both performing statistical testing and fitting distributions. In addition, the models are presented in a clear and precise pseudo-code form, which aids in understanding and model communication. Simulation Modeling and Arena, Second Edition also features: Updated coverage of necessary statistical modeling concepts such as confidence interval construction, hypothesis testing, and parameter estimation Additional examples of the simulation clock within discrete event simulation modeling involving the mechanics of time advancement by hand simulation A guide to the Arena Run Controller, which features a debugging scenario New homework problems that cover a wider range of engineering applications in transportation, logistics, healthcare, and computer science A related website with an Instructor’s Solutions Manual, PowerPoint® slides, test bank questions, and data sets for each chapter Simulation Modeling and Arena, Second Edition is an ideal textbook for upper-undergraduate and graduate courses in modeling and simulation within statistics, mathematics, industrial and civil engineering, construction management, business, computer science, and other departments where simulation is practiced. The book is also an excellent reference for professionals interested in mathematical modeling, simulation, and Arena.

Download or read book Healthcare Simulation Education written by Debra Nestel and published by John Wiley & Sons. This book was released on 2017-03-14 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a leading team from the Australian Society for Simulation in Healthcare (ASSH), Simulation Australasia, Healthcare Simulation Education is a new resource for a rapidly expanding professional healthcare simulation community. Designed as a core reference for educators who use simulation as an educational method, it outlines theory, evidence and research relevant to healthcare simulation. Containing examples of innovations from around the world, the book offers opportunities to make clear connections between the underlying rationale for the use of simulation, and what this looks like in practice. Healthcare Simulation Education: Helps readers gain a systematic understanding of theory and application of simulation Facilitates access to high quality resources to support healthcare simulation education and research Edited by a leading team from the Australian Society for Simulation in Healthcare (ASSH), the leading body for healthcare simulation in Australia Contains information on educational theory, the elements of simulation practice and contemporary issues in simulation An important text in healthcare literature and practice, Healthcare Simulation Education provides a unique cross-disciplinary overview of an innovative subject area, and is ideal for medical, nursing and allied health educators, policy makers and researchers.

Download or read book Simulation Modeling and Analysis with Expertfit Software written by Averill Law and published by McGraw-Hill Science/Engineering/Math. This book was released on 2006-07-21 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition in 1982, the goal of Simulation Modeling and Analysis has always been to provide a comprehensive, state-of-the-art, and technically correct treatment of all important aspects of a simulation study. The book strives to make this material understandable by the use of intuition and numerous figures, examples, and problems. It is equally well suited for use in university courses, simulation practice, and self study. The book is widely regarded as the “bible” of simulation and now has more than 100,000 copies in print. The book can serve as the primary text for a variety of courses; for example: • A first course in simulation at the junior, senior, or beginning-graduate-student level in engineering, manufacturing, business, or computer science (Chaps. 1 through 4, and parts of Chaps. 5 through 9). At the end of such a course, the students will be prepared to carry out complete and effective simulation studies, and to take advanced simulation courses. • A second course in simulation for graduate students in any of the above disciplines (most of Chaps. 5 through 12). After completing this course, the student should be familiar with the more advanced methodological issues involved in a simulation study, and should be prepared to understand and conduct simulation research. • An introduction to simulation as part of a general course in operations research or management science (part of Chaps. 1, 3, 5, 6, and 9).

Download or read book Building Software for Simulation written by James J. Nutaro and published by John Wiley & Sons. This book was released on 2011-03-23 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building Software for Simulation A unique guide to the design and implementation of simulation software This book offers a concise introduction to the art of building simulation software, collecting the most important concepts and algorithms in one place. Written for both individuals new to the field of modeling and simulation as well as experienced practitioners, this guide explains the design and implementation of simulation software used in the engineering of large systems while presenting the relevant mathematical elements, concept discussions, and code development. The book approaches the topic from the perspective of Zeigler’s theory of modeling and simulation, introducing the theory’s fundamental concepts and showing how to apply them to engineering problems. Readers will learn five necessary skills for building simulations of complicated systems: Working with fundamental abstractions for simulating dynamic systems Developing basic simulation algorithms for continuous and discrete event models Combining continuous and discrete event simulations into a coherent whole Applying strategies for testing a simulation Understanding the theoretical foundations of the modeling constructs and simulation algorithms The central chapters of the book introduce, explain, and demonstrate the elements of the theory that are most important for building simulation tools. They are bracketed by applications to robotics, control and communications, and electric power systems; these comprehensive examples clearly illustrate how the concepts and algorithms are put to use. Readers will explore the design of object-oriented simulation programs, simulation using multi-core processors, and the integration of simulators into larger software systems. The focus on software makes this book particularly useful for computer science and computer engineering courses in simulation that focus on building simulators. It is indispensable reading for undergraduate and graduate students studying modeling and simulation, as well as for practicing scientists and engineers involved in the development of simulation tools.