Download or read book Miracle Drugs vs Superbugs Preserving the Usefulness of Antibiotics written by and published by DIANE Publishing. This book was released on with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms of antibiotic resistance written by Jun Lin and published by Frontiers Media SA. This book was released on 2015-06-01 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
Download or read book Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine written by National Academies Of Sciences Engineeri and published by National Academies Press. This book was released on 2022-07-20 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Strategy for Combating Antibiotic Resistant Bacteria, published in 2014, sets out a plan for government work to mitigate the emergence and spread of resistant bacteria. Direction on the implementation of this strategy is provided in five-year national action plans, the first covering 2015 to 2020, and the second covering 2020 to 2025. Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine evaluates progress made against the national strategy. This report discusses ways to improve detection of resistant infections and estimate the risk to human health from environmental sources of resistance. In addition, the report considers the effect of agricultural practices on human and animal health and animal welfare and ways these practices could be improved, and advises on key drugs and diseases for which animal-specific test breakpoints are needed.
Download or read book Antibiotic Resistance written by Institute of Medicine and published by National Academies Press. This book was released on 2011-01-10 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant pathogens, the implications for global health, and the strategies to lessen the current and future impact of these superbugs.
Download or read book Superbug written by Maryn McKenna and published by Simon and Schuster. This book was released on 2010-03-23 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: LURKING in our homes, hospitals, schools, and farms is a terrifying pathogen that is evolving faster than the medical community can track it or drug developers can create antibiotics to quell it. That pathogen is MRSA—methicillin-resistant Staphyloccocus aureus—and Superbug is the first book to tell the story of its shocking spread and the alarming danger it poses to us all. Doctors long thought that MRSA was confined to hospitals and clinics, infecting almost exclusively those who were either already ill or old. But through remarkable reporting, including hundreds of interviews with the leading researchers and doctors tracking the deadly bacterium, acclaimed science journalist Maryn McKenna reveals the hidden history of MRSA’s relentless advance—how it has overwhelmed hospitals, assaulted families, and infiltrated agriculture and livestock, moving inexorably into the food chain. Taking readers into the medical centers where frustrated physicians must discard drug after drug as they struggle to keep patients alive, she discloses an explosion of cases that demonstrate how MRSA is growing more virulent, while evolving resistance to antibiotics with astonishing speed. It may infect us at any time, no matter how healthy we are; it is carried by a stunning number of our household pets; and it has been detected in food animals from cows to chickens to pigs. With the sensitivity of a novelist, McKenna portrays the emotional and financial devastation endured by MRSA’s victims, vividly describing the many stealthy ways in which the pathogen overtakes the body and the shock and grief of parents whose healthy children were felled by infection in just hours. Through dogged detective work, she discloses the unheard warnings that predicted the current crisis and lays bare the flaws that have allowed MRSA to rage out of control: misplaced government spending, inadequate public health surveillance, misguided agricultural practices, and vast overuse of the few precious drugs we have left. Empowering readers with the knowledge they need for self-defense, Superbug sounds an alarm: MRSA has evolved into a global emergency that touches almost every aspect of modern life. It is, as one deeply concerned researcher tells McKenna, "the biggest thing since AIDS."
Download or read book FDA Consumer written by and published by . This book was released on 2000 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microbes Fight Back written by Laura Bowater and published by Royal Society of Chemistry. This book was released on 2017-10-25 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics are familiar drugs to us all, so familiar that we may take them for granted. They allow us to survive life-threatening infections, and allow us to protect the animals we farm for food. Many antibiotics have now become ineffective against common diseases, and there are few alternative treatments to replace them. In this topical popular science book, Laura Bowater, Professor of Microbiology Education and Engagement at Norwich Medical School, considers the past, present and uncertain future of antibiotics. This book begins by looking back at how infectious diseases, such as smallpox and the plague, were able to wreak havoc on populations before the discovery of the first antibiotics. These then revolutionised the medical world. In an engaging and accessible style, Professor Bowater takes the reader through how antibiotics are made, how bacteria are able to mutate and develop resistance and she explains why there is now a lack of new antibiotic drugs coming to market. What will a future of continued antibiotic resistance look like? How can human activities prevent the rise of ‘superbugs'? Professor Bowater highlights the need for universal cooperation in order to tackle this global health challenge, which, if not addressed, could transport us back to the medical dark ages.
Download or read book Boston College Environmental Affairs Law Review written by Boston College. Law School and published by . This book was released on 2000 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hidden Dangers written by Betsy Gunzelmann and published by R&L Education. This book was released on 2012 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Hidden Dangers in our schools have grown and intensified over the last few years; so much so that I was compelled to write a second edition to Hidden Dangers: Subtle Signs of Failing Schools. Our schools are complex places; each with its own unique climate, administration, faculty, students, parents and community members. Clearly, schools do not work in a vacuum; each is affected by the much larger society, government and economy. In this new edition we will be introduced to the interplay of these facets and how they can help and in some cases hinder our schools, our teachers, and our students from thriving. We also learn why it is more complicated now than ever, and the stakes are even higher than when Hidden Dangers was originally published back in 2008
Download or read book Extending the Cure written by Ramanan Laxminarayan and published by Routledge. This book was released on 2010-09-30 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our ability to treat common bacterial infections with antibiotics goes back only 65 years. However, the authors of this report make it clear that sustaining a supply of effective and affordable antibiotics cannot be without changes to the incentives facing patients, physicians, hospitals, insurers, and pharmaceutical manufacturers. In fact, increasing resistance to these drugs is already exacting a terrible price. Every day in the United States, approximately 172 men, women, and children die from infections caused by antibiotic-resistant bacteria in hospitals alone. Beyond those deaths, antibiotic resistance is costing billions of dollars through prolonged hospital stays and the need for doctors to resort to ever more costly drugs to use as substitute treatments. Extending the Cure presents the problem of antibiotic resistance as a conflict between individual decision makers and their short-term interest and the interest of society as a whole, in both present and future: The effort that doctors make to please each patient by prescribing a drug when it might not be properly indicated, poor monitoring of discharged patients to ensure that they do not transmit drug-resistant pathogens to other persons, excesses in the marketing of new antibiotics, and the broad overuse of antibiotics all contribute to the development and spread of antibiotic-resistant bacteria. The book explores a range of policy options that would encourage patients, health care providers, and managed care organizations to serve as more responsible stewards of existing antibiotics as well as proposals that would give pharmaceutical firms greater incentives to develop new antibiotics and avoid overselling. If the problem continues unaddressed, antibiotic resistance has the potential to derail the health care system and return us to a world where people of all ages routinely die from simple infections. As a basis for future research and a spur to a critically important dialogue, Extending the Cure is a fundamental first step in addressing this public health crisis. The Extending the Cure project is funded in part by the Robert Wood Johnson Foundation through its Pioneer Portfolio.
Download or read book The Perfect Predator written by Steffanie Strathdee and published by Hachette Books. This book was released on 2019-02-26 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: An electrifying memoir of one woman's extraordinary effort to save her husband's life-and the discovery of a forgotten cure that has the potential to save millions more. "A memoir that reads like a thriller." -New York Times Book Review "A fascinating and terrifying peek into the devastating outcomes of antibiotic misuse-and what happens when standard health care falls short." -Scientific American Epidemiologist Steffanie Strathdee and her husband, psychologist Tom Patterson, were vacationing in Egypt when Tom came down with a stomach bug. What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world. Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure. A nail-biting medical mystery, The Perfect Predator is a story of love and survival against all odds, and the (re)discovery of a powerful new weapon in the global superbug crisis.
Download or read book Farm Sanctuary written by Gene Baur and published by Simon and Schuster. This book was released on 2008-03-04 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading animal rights activist Gene Baur examines the real cost of the meat on our plates -- for both humans and animals alike -- in this provocative and thorough examination of the modern farm industry. Many people picture cows, sheep, pigs, and chickens as friendly creatures who live happily within the confines of a peaceful family farm, arriving as food for humans only at the end of their sun-drenched lives. That's what Gene Baur had been told -- but when he first visited a stockyard he realized that this rosy depiction couldn't be more inaccurate. Amid the stench, noise, and filth, his attention was drawn in particular to one sheep who had been cast aside for dead. But as Baur walked by, the sheep raised her head and looked right at him. She was still alive, and the one thing Baur knew for sure that day was that he had to get her to safety. Hilda, as she was later named, was nursed back to health and soon became the first resident of Farm Sanctuary -- an organization dedicated to the rescue, care, and protection of farm animals. The truth is that farm production does not depend on the family farmer with a small herd of animals but instead resembles a large, assembly-line factory. Animals raised for human consumption are confined for the entirety of their lives and often live without companionship, fresh air, or even adequate food and water.Viewed as production units rather than living beings with feelings, ten billion farm animals are exploited specifically for food in the United States every year. In Farm Sanctuary, Baur provides a thoughtprovoking investigation of the ethical questions involved in the production of beef, poultry, pork, milk,and eggs -- and what each of us can do to stop the mistreatment of farm animals and promote compassion. He details the triumphs and the disappointments of more than twenty years on the front lines of the animal protection movement. And he introduces sanctuary. us to some of the special creatures who live at Farm Sanctuary -- from Maya the cow to Marmalade the chicken -- all of whom escaped horrible circumstances to live happier, more peaceful lives. Farm Sanctuary shows how all of us have an opportunity and a responsibility to consume a kinder plate, making a better life for ourselves and animals as well. You will certainly never think of a hamburger or chicken breast the same way after reading this book.
Download or read book Social Work Practice and Psychopharmacology Second Edition written by Sophia Dziegielewski PhD, LCSW and published by Springer Publishing Company. This book was released on 2009-12-07 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why do social workers need to know about mental health medications? How can social workers best assist clients who are taking medications? What is the social worker's role as part of the interdisciplinary health care team? Answering these questions and more, this comprehensive text discusses the major medications used to treat common mental health conditions and offers guidelines on how to best serve clients who are using them. This new edition provides guidance on many issues that social workers will encounter in practice, including identifying potentially dangerous drug interactions and adverse side effects; improving medication compliance; recognizing the warning signs of drug dependence; and understanding how psychopharmacology can work in conjunction with psychosocial interventions. Complete with case examples, assessment tools, and treatment plans, this book offers practical insight for social work students and social workers serving clients with mental health conditions. New to this edition are expanded discussions of child and adolescent disorders, engaging discussions of how new drugs are created, approved, and marketed, and a new glossary describing over 150 common medications and herbal remedies. Important Topics Discussed: Treatment of common mental health conditions, such as depression, anxiety disorders, schizophrenia, and dementia Taking a comprehensive medication history Understanding medical terminology Avoiding drug misuse, dependence, and overdose
Download or read book Typhoid Fever written by Donald Emmeluth and published by Infobase Publishing. This book was released on 2009 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the early history, the name Mary Mallon ("Typhoid Mary") will always be linked with typhoid fever.
Download or read book Microbial Evolution and Co Adaptation written by Institute of Medicine and published by National Academies Press. This book was released on 2009-05-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.
Download or read book Viruses Vs Superbugs written by T. Häusler and published by Springer. This book was released on 2016-05-24 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year thousands of people die from bacteria resistant to antibiotics. Alternative drugs are urgently needed. A surprising ray of hope from the past are viruses that kill bacteria, but not us. Award-winning science journalist Thomas Häusler investigates how these long-forgotten cures may help sick people today.
Download or read book The Drugs Don t Work written by Professor Dame Sally Davies and published by Penguin UK. This book was released on 2013-09-15 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Drugs Don't Work - A Penguin Special by Professor Dame Sally Davies, the Chief Medical Officer for England 'If we fail to act, we are looking at an almost unthinkable scenario where antibiotics no longer work and we are cast back into the dark ages of medicine where treatable infections and injuries will kill once again' David Cameron, Prime Minister Resistance to our current range of antibiotics is the new inconvenient truth. If we don't act now, we risk the health of our parents, our children and our grandchildren. Antibiotics add, on average, twenty years to our lives. For over seventy years, since the manufacture of penicillin in 1943, we have survived extraordinary operations and life-threatening infections. We are so familiar with these wonder drugs that we take them for granted. The truth is that we have been abusing them: as patients, as doctors, as travellers, in our food. No new class of antibacterial has been discovered for twenty six years and the bugs are fighting back. If we do not take responsibility now, in a few decades we may start dying from the most commonplace of operations and ailments that can today be treated easily. This short book, which will be enjoyed by readers of An Inconvenient Truth by Al Gore and Bad Pharma by Ben Goldacre, will be the subject of a TEDex talk given by Professor Dame Sally Davies at the Royal Albert Hall. Professor Dame Sally C. Davies is the Chief Medical Officer for England and the first woman to hold the post. As CMO she is the independent advisor to the Government on medical matters with particular interest in Public Health and Research. She holds a number of international advisory positions and is an Emeritus Professor at Imperial College. Dr Jonathan Grant is a Principal Research Fellow and former President at RAND Europe, a not-for-profit public policy research institute. His main research interests are on health R&D policy and the use of research and evidence in policymaking. He was formerly Head of Policy at The Wellcome Trust. He received his PhD from the Faculty of Medicine, University of London, and his B.Sc. (Econ) from the London School of Economics. Professor Mike Catchpole is an internationally recognized expert in infectious diseases and the Director of Infectious Disease Surveillance and Control at Public Health England. He has coordinated many national infectious disease outbreak investigations and is an advisor to the European Centre for Disease Prevention and Control. He is also a visiting professor at Imperial College.
