Download or read book Microprobe Analysis in Medicine written by Peter Ingram and published by . This book was released on 1989 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: A work reviewing the applications of new microprobe analysis techniques in medicine. Authoritative chapters illustrate a variety of techniques and demonstrate appropriate applications to specific diseases. Key coverage includes pulmonary pathology and asbestoses.
Download or read book Microprobe Analysis in Biology and Medicine written by Patrick Echlin and published by . This book was released on 1978 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomedical Applications of Microprobe Analysis written by Peter Ingram and published by Academic Press. This book was released on 1999-10-29 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Applications of Microprobe Analysis is a combination reference/laboratory manual for the use of microprobe analysis in both clinical diagnostic and research settings. Also called microchemical microscopy, microprobe analysis uses high-energy bombardment of cells and tissue, in combination with high resolution EM or confocal microscopy to provide a profile of the ion, metal, and mineral concentrations present in a sample. This allows insight into the physiology and pathophysiology of a wide variety of cells and tissues.This book describes methods for obtaining detailed information about the identity and composition of particles too small to be seen with the naked eye and describes how this information can be useful in diagnostic and biomedical research. Up-to-date review of electron microprobe analysis Detailed descriptions of sample preparation techniques Recent technologies including confocal microscopy, infrared microspectroscopy, and laser raman spectroscopy Over 100 illustrations with numerous specific applications Contributions by world-renowned experts in the field Brief summary of highlights precedes each chapter
Download or read book Electron Probe Microanalysis written by Karl Zierold and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of electron probe microanalysis of biological systems is to identify, localize, and quantify elements, mass, and water in cells and tissues. The method is based on the idea that all electrons and photons emerging from an electron beam irradiated specimen contain information on its structure and composition. In particular, energy spectroscopy of X-rays and electrons after interaction of the electron beam with the specimen is used for this purpose. However, the application of this method in biology and medicine has to overcome three specific problems: 1. The principle constituent of most cell samples is water. Since liquid water is not compatible with vacuum conditions in the electron microscope, specimens have to be prepared without disturbing the other components, in parti cular diffusible ions (elements). 2. Electron probe microanaly sis provides physical data on either dry specimens or fully hydrated, frozen specimens. This data usually has to be con verted into quantitative data meaningful to the cell biologist or physiologist. 3. Cells and tissues are not static but dynamic systems. Thus, for example, microanalysis of physiolo gical processes requires sampling techniques which are adapted to address specific biological or medical questions. During recent years, remarkable progress has been made to overcome these problems. Cryopreparation, image analysis, and electron energy loss spectroscopy are key areas which have solved some problems and offer promise for future improvements.
Download or read book Applications of Nuclear Microprobe in the Life Sciences written by Yvan Llabador and published by World Scientific. This book was released on 1998 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: "... this book will be particularly useful to the many biologists encountering problems of elemental analysis & analytical imaging who wish to have a clear yet comprehensive introduction to the principles, the conditions of application & the potential of nuclear microprobes compared with those of alternative methods." Journal of Trace & Microprobe Techniques, 1999
Download or read book Electron Microscopy in Human Medicine written by Jan Vincents Johannessen and published by McGraw-Hill Companies. This book was released on 1983 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Electron Microprobe Analysis written by S. J. B. Reed and published by Cambridge University Press. This book was released on 1997-07-10 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 1993 book gives a comprehensive account of both experimental and theoretical aspects of electron microprobe analysis, and is an extensively updated version of the seminal first edition, published in 1975. The design and operation of the instrument, including the electron column and both wavelength- and energy-dispersive X-ray spectrometers, are covered in the first part of the book. Experimental procedures for qualitative and quantitative analysis, using both types of spectrometer, are then discussed. Matrix ('ZAF') corrections, as required for quantitative analysis, are treated in some detail from both theoretical and practical viewpoints. Special considerations applying to the analysis of 'light' elements (atomic number below 10) are covered in a separate chapter. The emphasis throughout is on a sound understanding of principles and the treatment is applicable equally to the electron microprobe in its 'classical' form and to scanning electron microscopes fitted with X-ray spectrometers.
Download or read book Quantitative Electron Microprobe Analysis written by Roger Theisen and published by Springer. This book was released on 1965 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Electron "licroprobe X-!{ay Analyscr conceivcd b ' R C.\S'L\I: \G and A. Cl'!: '\ lEI( in 1949 has been developcd as an extremelv po\\'crful tool in spcctrochcmical analysis for a wide range of applications, ranging from qualitative elcmcntary distribution studies, to highly localiscd quantitatin analysis on a one micron scale. \\'ith the increasing number oi' versatile instruments, commcrcially available, the domain of applications - in metallurgy, solid state physics, mineralogy and geology, biology and medicine, arts and archeology - is rapidly expanding, particularly because reliable quantitative analyses can be achieved. It is well established that in multicomponent specimens, the relative x-ray intensity generated by the electron bombardment - i.e. the intensity ratio of the characteristic x-ray radiation emitted under identical experimental conditions by the specimen and a calibration standard - is not directly correlated to the elementary mass concentration. The use of a wide scale of carefully prepared homogeneous calibration standards is generally very tedious and restricted to binar)' systems. For more complex specimens, the conversion of recorded x-ra)' intensity ratios to elementary mass concentration requires, besides carefule selection of experimental conditions, an adequate correction calculation to take account oi' the various physical phenomenas occurring in the tarp;et - electron retardation, electron backseattering, x-ray excitation efficieney, fluorescence enhaneement by eharaeteristic and continuous radiation and x-ray mass absorption.
Download or read book Microprobe Analysis of Biological Systems written by Thomas Hutchinson and published by Elsevier. This book was released on 2012-12-02 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microprobe Analysis of Biological Systems covers the proceedings of the 1980 Microprobe Analysis of Biological Systems conference held at Battelle Conference Center in Seattle, Washington. Most of the major laboratories in the field of biological microanalysis in the United States, England, Scotland, France, and Germany are represented. The conference presents the findings, theories, techniques, and procedures of the laboratory represented, no matter how tentative and exploratory. This book is divided into four parts encompassing 22 chapters that focus on biological applications of microprobe analysis. The introductory part describes the application of electron microprobe and X-ray microanalyses in studies of epithelial transport, avian salt gland, electrolyte transport, and acrosome reaction. The subsequent part covers the application of microprobe techniques in the analysis of cardiac, skeletal, vascular smooth, and freeze-dried muscles. It also describes a method for obtaining erythrocyte preparations for validating biological microprobe methods and the continuum-fluorescence effect on thick biological tissue. The method using freeze-substitution to localize calcium in quick-frozen tissue for X-ray microanalysis is also explained. The third part of the book tackles the principles, basic features, and applications of electron energy-loss spectroscopy. Discussions on the use of inner-shell signals for a quantitative local microanalysis technique; theoretical study of the energy resolution; and collection efficiency of a magnetic spectrometer are also included. The final part covers the elemental distribution in single erythrocytes using X-ray microanalysis. It also discusses the fundamentals of cryosectioning process for X-ray microanalysis of diffusible elements and the freezing behavior of a number of chemically different gels chosen for their partial resemblance to biological structures. Considerable chapters contain materials and methods, results, discussions, conclusions, and references. This book will be of value to scientists interested in elemental and ion transport within cells and between cells and extracellular compartments.
Download or read book Advanced Scanning Electron Microscopy and X Ray Microanalysis written by Patrick Echlin and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has its origins in the intensive short courses on scanning elec tron microscopy and x-ray microanalysis which have been taught annually at Lehigh University since 1972. In order to provide a textbook containing the materials presented in the original course, the lecturers collaborated to write the book Practical Scanning Electron Microscopy (PSEM), which was published by Plenum Press in 1975. The course con tinued to evolve and expand in the ensuing years, until the volume of material to be covered necessitated the development of separate intro ductory and advanced courses. In 1981 the lecturers undertook the project of rewriting the original textbook, producing the volume Scan ning Electron Microscopy and X-Ray Microanalysis (SEMXM). This vol ume contained substantial expansions of the treatment of such basic material as electron optics, image formation, energy-dispersive x-ray spectrometry, and qualitative and quantitative analysis. At the same time, a number of chapters, which had been included in the PSEM vol ume, including those on magnetic contrast and electron channeling con trast, had to be dropped for reasons of space. Moreover, these topics had naturally evolved into the basis of the advanced course. In addition, the evolution of the SEM and microanalysis fields had resulted in the devel opment of new topics, such as digital image processing, which by their nature became topics in the advanced course.
Download or read book Essentials of Medical Geology written by Olle Selinus and published by Springer Science & Business Media. This book was released on 2013-03-30 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Medical Geology reviews the essential concepts and practical tools required to tackle environmental and public health problems. It is organized into four main sections. The first section deals with the fundamentals of environmental biology, the natural and anthropogenic sources of health elements that impact health and illustrate key biogeochemical transformations. The second section looks at the geological processes influencing human exposure to specific elements, such as radon, arsenic, fluorine, selenium and iodine. The third section presents the concepts and techniques of pathology, toxicology and epidemiology that underpin investigations into the human health effects of exposure to naturally occurring elements. The last section provides a toolbox of analytical approaches to environmental research and medical geology investigations. Essentials of Medical Geology was first published in 2005 and has since won three prestigious rewards. The book has been recognized as a key book in both medical and geology fields and is widely used as textbook and reference book in these fields. For this revised edition, editors and authors have updated the content that evolved a lot during 2005 and added two new chapters, on public health, and agriculture and health. This updated volume can now continue to be used as a textbook and reference book for all who are interested in this important topic and its impacts the health and wellbeing of many millions of people all over the world. · Addresses key topics at the intersection of environmental science and human health · Developed by 60 international experts from 20 countries and edited by professionals from the International Medical Geology Association (IMGA) · Written in non-technical language for a broad spectrum of readers, ranging from students and professional researchers to policymakers and the general public · Includes color illustrations throughout, references for further investigation and other aids to the reader
Download or read book X ray Microscopy in Clinical and Experimental Medicine written by Theodore Alvin Hall and published by Charles C. Thomas Publisher. This book was released on 1972 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Application of Laser Microprobe Mass Analysis LAMMA to Biology and Medicine written by Armand Verbueken and published by . This book was released on 1985 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Electron Microprobe Analysis written by S. J. B. Reed and published by . This book was released on 1993-01-28 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1993 paperback of successful physics monograph on electron microprobe analysis, a widely used technique.
Download or read book Electron Microprobe Analysis and Scanning Electron Microscopy in Geology written by S. J. B. Reed and published by Cambridge University Press. This book was released on 2005-08-25 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in 2005, this book covers the closely related techniques of electron microprobe analysis (EMPA) and scanning electron microscopy (SEM) specifically from a geological viewpoint. Topics discussed include: principles of electron-target interactions, electron beam instrumentation, X-ray spectrometry, general principles of SEM image formation, production of X-ray 'maps' showing elemental distributions, procedures for qualitative and quantitative X-ray analysis (both energy-dispersive and wavelength-dispersive), the use of both 'true' electron microprobes and SEMs fitted with X-ray spectrometers, and practical matters such as sample preparation and treatment of results. Throughout, there is an emphasis on geological aspects not mentioned in similar books aimed at a more general readership. The book avoids unnecessary technical detail in order to be easily accessible, and forms a comprehensive text on EMPA and SEM for geological postgraduate and postdoctoral researchers, as well as those working in industrial laboratories.
Download or read book Electron Microprobe Analysis written by Stephen Jervis Brent Reed and published by . This book was released on 1993 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Electron Microprobe Analysis and Scanning Electron Microscopy in Geology written by S. J. B. Reed and published by . This book was released on 2005 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reed describes the important techniques of electron microprobe analysis (EMPA) and scanning electron microscopy (SEM), as used in many branches of geology, including petrology, mineralogy, palaeontology and sedimentology.
