Download or read book Micromanipulation by Light in Biology and Medicine written by Karl Otto Greulich and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are probably few people who do not dream of the good old times, when do ing science often meant fascination, excitement, even adventure. In our time, do ing science involves often technology and, perhaps, even business. But there are still niches where curiosity and fascination have their place. The subject of this book, technological as its title may sound, is one of the fortunate examples. It will report on lasers generating the coldest places in the Universe, and on table top laser microtools which can produce a heat "inferno" as it prevails in the interior of the Sun, or simulate, for specific plant cells, microgravity of the space around our plan et Earth. There will be some real surprises for the reader. The applications range from basic studies of the driving forces of cell division (and thus life) via genetic modification of cells (for example, for plant breeding) to medical applications such as blood cell analysis and finally in vitro fertilization. What are these instruments: laser microbeams and optical tweezers? Both are lasers coupled with a fluorescence microscope. The laser microbeam uses a pulsed ultraviolet laser. Light is focused, as well as possible, in space and time, in order to obtain extremely high light intensities - high enough to generate, for a very short instant, extremely hot spots which can be used to cut, fuse or perforate biological material.

Download or read book Micromanipulation in Assisted Conception written by Steven D. Fleming and published by Cambridge University Press. This book was released on 2003-11-06 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide to micromanipulation techniques, for assisted conception in a clinical setting, includes detailed descriptions of all common micromanipulation systems currently in use in IVF laboratories. In explaining how to optimize their successful use, the volume covers state-of-the-art techniques including ICSI, and procedures such as assisted hatching and the blastomere biopsy (for PGD). Valuable information on troubleshooting mechanical and technical difficulties is provided to help professionals ranging from technicians to consultant obstetricians master the techniques.

Download or read book Manual of Intracytoplasmic Sperm Injection in Human Assisted Reproduction written by Gianpiero D. Palermo and published by Cambridge University Press. This book was released on 2021-11-25 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Not everything in medical science has a clear beginning. The first realization of infertility and putative remedies remain shrouded in contextual history, but likely goes back to the dawn of our species, well before there was a written record. Childlessness was, and is still, considered a burden in some communities"--

Download or read book Micromanipulators and Micromanipulation written by Hamed M. El-Badry and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the course of the years since H. D. SCHMIDT, in 1895, describcd his "microscopic dissector," a mechanical device for dissecting and study ing biological materials, a great wealth of information has been pub lished in the scientific and technical literature on methods involving the use of exceedingly delicate microtools mechanically guided under microscopic control for the investigation of microscopic structures and very small amounts of material.. The operative tools used can be moved with considerable precision under various microscopic magnifications to perform the required tasks. With the continuous progress in these methods, hundreds of micro manipulators and other mechanical manipulativc devices, auxiliaryequip ment, and a great diversity of microtools have been described for per forming varied operations on practically any type of materials and test objects. Thus, micromanipulative and related techniques have become innumerable and often intricate, and the applications, formerly confined to certain fields of biology and medicine, have been extended to the most diverse fields of science and technology as mtn be Been from a rapid glance at the contents of the presEmt volume.

Download or read book Structured Light and Its Applications written by David L. Andrews and published by Academic Press. This book was released on 2011-08-29 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: New possibilities have recently emerged for producing optical beams with complex and intricate structures, and for the non-contact optical manipulation of matter. Structured Light and Its Applications fully describes the electromagnetic theory, optical properties, methods and applications associated with this new technology. Detailed discussions are given of unique beam characteristics, such as optical vortices and other wavefront structures, the associated phase properties and photonic aspects, along with applications ranging from cold atom manipulation to optically driven micromachines. Features include: Comprehensive and authoritative treatments of the latest research in this area of nanophotonics, written by the leading researchers Accounts of numerous microfluidics, nanofabrication, quantum informatics and optical manipulation applications Coverage that fully spans the subject area, from fundamental theory and simulations to experimental methods and results Graduate students and established researchers in academia, national laboratories and industry will find this book an invaluable guide to the latest technologies in this rapidly developing field. Comprehensive and definitive source of the latest research in nanotechnology written by the leading people in the field From theory to applications - all is presented in detail Editor is Chair of the SPIE Nanotechnology Technical Group and is leading the way in generation and manipulation of complex beams

Download or read book Microrobotics for Micromanipulation written by Nicolas Chaillet and published by John Wiley & Sons. This book was released on 2013-03-04 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microrobotics is an emerging and booming area with many and various applications, including in fields such as industrial/manufacturing robotics, medical robotics, and laboratory instrumentation. Microrobotics for Micromanipulation presents for the first time, in detail, a treatment of the field of robotics dedicated to handling objects of micrometer dimensions. At these dimensions, the behavior of objects is significantly different from the better known, larger scales, which leads to implementation techniques that can be radically different from the more commonly used solutions. This book details the behaviors of objects at the micrometer scale and provides robotics solutions that are suitable, in terms of actuators, grippers, manipulators, environmental perception, and microtechnology. Worked examples are included in the book - enabling engineers, students and researchers to familiarize themselves with this emerging area and to contribute to its development.

Download or read book Capillary Forces in Microassembly written by Pierre Lambert and published by Springer Science & Business Media. This book was released on 2007-08-29 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Capillary Forces in Microassembly discusses the use of capillary forces as a gripping principle in microscale assembly. Clearly written and well-organized, this text brings together physical concepts at the microscale with practical applications in micromanipulation. Throughout this work, the reader will find a review of the existing gripping principles, elements to model capillary forces as well as descriptions of the simulation and experimental test bench developed to study the design parameters. Using well-known concepts from surface science (such as surface tension, capillary effects, wettability, and contact angles) as inputs to mechanical models, the amount of effort required to handle micro-components is then predicted. Researchers and engineers involved in micromanipulation and precision assembly will find this a highly useful reference for microassembly system design and analysis.

Download or read book In Vitro Fertilization written by Zsolt Peter Nagy and published by Springer. This book was released on 2019-07-03 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its revised and expanded second edition - including over 20 new chapters - this comprehensive textbook remains a unique and accessible description of the current and developing diagnostic and treatment techniques and technologies comprising in vitro fertilization (IVF). Arranged thematically in sections, each chapter covers a key topic in IVF in a sensible presentation. Parts one and two describe the planning, design and organization of an ART unit and IVF laboratory and equipment and systems, respectively. The sections that follow provide detailed descriptions of IVF techniques, embryo culture methods, sperm processing and selection, insemination procedures, micromanipulation, embryo evaluation, cryopreservation, and embryo transfer. Concluding sections address issues of management and regulation of ART labs across the globe, as well as special topics and emerging techniques and devices. Chapter authors, all experts in the field, contribute their expertise from around the world. With the addition of learning key points and review questions at the beginning and end of each chapter, this new edition of In Vitro Fertilization is a readily accessible, high quality instructional resource for reproductive medicine trainees at all levels. Practicing reproductive endocrinologists, urologists, and embryologists also will find value in the book, as will infertility researchers.

Download or read book Robotic Micromanipulation of Zebrafish Larva written by Songlin Zhuang and published by Springer Nature. This book was released on 2023-07-22 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers readers a series of robotic methods for manipulating zebrafish larva, one of the most popular model vertebrates widely used in biomedical research and clinical applications. The authors leverage advanced control theories, image processing algorithms, and artificial intelligence to establish a robot-assisted automated or semi-automated zebrafish larva-targeted micromanipulation system for different experimental purposes. The methods presented are generic and can be translated to manipulate other types of biological objects, such as embryos or cells. Coverage includes topics that span the procedures of manipulating zebrafish larva, such as in-plane positioning, three-dimensional orientation, deformation-controllable immobilization, organ-targeted microinjection, whole-organism imaging, and high-throughput trajectory tracking of zebrafish larvae group movement. Robotic Micromanipulation of Zebrafish Larva is written in a simple, clear, and easy-to-read style. It is an ideal reference for academic researchers and biomedical operators. It is also a valuable resource for students learning robotics, control and system theories, image processing, artificial intelligence, and biomedical engineering.

Download or read book Micromachines for Biological Micromanipulation written by Qingsong Xu and published by Springer. This book was released on 2018-02-01 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the noteworthy developments in the field of micromachining, with a specific focus on microinjection systems used for biological micromanipulation. The author also explores the design, development, and fabrication of new mechanical designs for micromachines, with plenty of examples that elucidate their modeling and control. The design and fabrication of a piezoelectric microinjector, constant force microinjector, constant force microgripper, PDVF microforce sensor, and a piezoelectric microsyringe are presented as examples of new technology for microinjection systems. This book is appropriate for both researchers and advanced students in bioengineering.

Download or read book Microbiorobotics written by Minjun Kim and published by William Andrew. This book was released on 2012-03-08 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiorobotics is a new engineering discipline that inherently involves a multidisciplinary approach (mechanical engineering, cellular biology, mathematical modeling, control systems, synthetic biology, etc). Building robotics system in the micro scale is an engineering task that has resulted in many important applications, ranging from micromanufacturing techniques to cellular manipulation. However, it is also a very challenging engineering task. One of the reasons is because many engineering ideas and principles that are used in larger scales do not scale well to the micro-scale. For example, locomotion principles in a fluid do not function in the same way, and the use of rotational motors is impractical because of the difficulty of building of the required components. Microrobotics is an area that is acknowledged to have massive potential in applications from medicine to manufacturing. This book introduces an inter-disciplinary readership to the toolkit that micro-organisms offer to micro-engineering The design of robots, sensors and actuators faces a range of techology challenges at the micro-scale. This book shows how biological techniques and materials can be used to meet these challenges World-class multi-disciplanry editors and contributors leverage insights from engineering, mathematical modeling and the life sciences – creating a novel toolkit for microrobotics

Download or read book Principles of Cloning written by Jose Cibelli and published by Academic Press. This book was released on 2013-09-24 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Cloning, Second Edition is the fully revised edition of the authoritative book on the science of cloning. The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine. Beginning with the history and theory behind cloning, the book goes on to examine methods of micromanipulation, nuclear transfer, genetic modification, and pregnancy and neonatal care of cloned animals. The cloning of various species—including mice, sheep, cattle, and non-mammals—is considered as well. The Editors have been involved in a number of breakthroughs using cloning technique, including the first demonstration that cloning works in differentiated cells done by the Recipient of the 2012 Nobel Prize for Physiology or Medicine – Dr John Gurdon; the cloning of the first mammal from a somatic cell – Drs Keith Campbell and Ian Wilmut; the demonstration that cloning can reset the biological clock - Drs Michael West and Robert Lanza; the demonstration that a terminally differentiated cell can give rise to a whole new individual – Dr Rudolf Jaenisch and the cloning of the first transgenic bovine from a differentiated cell – Dr Jose Cibelli. The majority of the contributing authors are the principal investigators on each of the animal species cloned to date and are expertly qualified to present the state-of-the-art information in their respective areas. - First and most comprehensive book on animal cloning, 100% revised - Describes an in-depth analysis of current limitations of the technology and research areas to explore - Offers cloning applications on basic biology, agriculture, biotechnology, and medicine

Download or read book Micromanipulation written by Nicola Pio Belfiore and published by MDPI. This book was released on 2019-01-10 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Micromanipulation" that was published in Actuators

Download or read book Microscale Surface Tension and Its Applications written by Pierre Lambert and published by MDPI. This book was released on 2019-10-21 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building on advances in miniaturization and soft matter, surface tension effects are a major key to the development of soft/fluidic microrobotics. Benefiting from scaling laws, surface tension and capillary effects can enable sensing, actuation, adhesion, confinement, compliance, and other structural and functional properties necessary in micro- and nanosystems. Various applications are under development: microfluidic and lab-on-chip devices, soft gripping and manipulation of particles, colloidal and interfacial assemblies, fluidic/droplet mechatronics. The capillary action is ubiquitous in drops, bubbles and menisci, opening a broad spectrum of technological solutions and scientific investigations. Identified grand challenges to the establishment of fluidic microrobotics include mastering the dynamics of capillary effects, controlling the hysteresis arising from wetting and evaporation, improving the dispensing and handling of tiny droplets, and developing a mechatronic approach for the control and programming of surface tension effects. In this Special Issue of Micromachines, we invite contributions covering all aspects of microscale engineering relying on surface tension. Particularly, we welcome contributions on fundamentals or applications related to: Drop-botics: fluidic or surface tension-based micro/nanorobotics: capillary manipulation, gripping, and actuation, sensing, folding, propulsion and bio-inspired solutions; Control of surface tension effects: surface tension gradients, active surfactants, thermocapillarity, electrowetting, elastocapillarity; Handling of droplets, bubbles and liquid bridges: dispensing, confinement, displacement, stretching, rupture, evaporation; Capillary forces: modelling, measurement, simulation; Interfacial engineering: smart liquids, surface treatments; Interfacial fluidic and capillary assembly of colloids and devices; Biological applications of surface tension, including lab-on-chip and organ-on-chip systems.

Download or read book Multiphoton Microscopy and Fluorescence Lifetime Imaging written by Karsten König and published by Walter de Gruyter GmbH & Co KG. This book was released on 2018-01-22 with total page 785 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph focuses on modern femtosecond laser microscopes for two photon imaging and nanoprocessing, on laser tweezers for cell micromanipulation as well as on fluorescence lifetime imaging (FLIM) in Life Sciences. The book starts with an introduction by Dr. Wolfgang Kaiser, pioneer of nonlinear optics and ends with the chapter on clinical multiphoton tomography, the novel high resolution imaging technique. It includes a foreword by the nonlinear microscopy expert Dr. Colin Sheppard. Contents Part I: Basics Brief history of fluorescence lifetime imaging The long journey to the laser and its use for nonlinear optics Advanced TCSPC-FLIM techniques Ultrafast lasers in biophotonics Part II: Modern nonlinear microscopy of live cells STED microscopy: exploring fluorescence lifetime gradients for super-resolution at reduced illumination intensities Principles and applications of temporal-focusing wide-field two-photon microscopy FLIM-FRET microscopy TCSPC FLIM and PLIM for metabolic imaging and oxygen sensing Laser tweezers are sources of two-photon effects Metabolic shifts in cell proliferation and differentiation Femtosecond laser nanoprocessing Cryomultiphoton imaging Part III: Nonlinear tissue imaging Multiphoton Tomography (MPT) Clinical multimodal CARS imaging In vivo multiphoton microscopy of human skin Two-photon microscopy and fluorescence lifetime imaging of the cornea Multiscale correlative imaging of the brain Revealing interaction of dyes and nanomaterials by multiphoton imaging Multiphoton FLIM in cosmetic clinical research Multiphoton microscopy and fluorescence lifetime imaging for resection guidance in malignant glioma surgery Non-invasive single-photon and multi-photon imaging of stem cells and cancer cells in mouse models Bedside assessment of multiphoton tomography

Download or read book Advanced Mechatronics and MEMS Devices II written by Dan Zhang and published by Springer. This book was released on 2016-10-18 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the state-of-the-art technologies in mechatronics, robotics, and MEMS devices in order to improve their methodologies. It provides a follow-up to "Advanced Mechatronics and MEMS Devices" (2013) with an exploration of the most up-to-date technologies and their applications, shown through examples that give readers insights and lessons learned from actual projects. Researchers on mechatronics, robotics, and MEMS as well as graduate students in mechanical engineering will find chapters on: Fundamental design and working principles on MEMS accelerometers Innovative mobile technologies Force/tactile sensors development Control schemes for reconfigurable robotic systems Inertial microfluidics Piezoelectric force sensors and dynamic calibration techniques ...And more. Authors explore applications in the areas of agriculture, biomedicine, advanced manufacturing, and space. Micro-assembly for current and future industries is also considered, as well as the design and development of micro and intelligent manufacturing.

Download or read book Structured Light Fields written by Mike Wördemann and published by Springer Science & Business Media. This book was released on 2012-05-16 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: The optical trapping of colloidal matter is an unequalled field of technology for enabling precise handling of particles on microscopic scales, solely by the force of light. Although the basic concept of optical tweezers, which are based on a single laser beam, has matured and found a vast number of exciting applications, in particular in the life sciences, there are strong demands for more sophisticated approaches. This thesis gives an introductory overview of existing optical micromanipulation techniques and reviews the state-of-the-art of the emerging field of structured light fields and their applications in optical trapping, micromanipulation, and organisation. The author presents established, and introduces novel concepts for the holographic and non-holographic shaping of a light field. A special emphasis of the work is the demonstration of advanced applications of the thus created structured light fields in optical micromanipulation, utilising various geometries and unconventional light propagation properties. While most of the concepts developed are demonstrated with artificial microscopic reference particles, the work concludes with a comprehensive demonstration of optical control and alignment of bacterial cells, and hierarchical supramolecular organisation utilising dedicated nanocontainer particles.