Download or read book Microcirculation in Circulatory Disorders written by Hisao Manabe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent progress in microvascular disorders including cerebral, myocardial and peripheral tissue ischemia, multiple organ failure and gastroenterological disorders. Knowledge of microcirculation is essential in order to understand thoroughly the mechanism of organ disorders. This book successfully elucidates the pathophysiologic significance of microcirculation in ischemia and other diseases. It is useful for basic researchers and clinicians who are interested in the early diagnosis and prevention of cardiovascular diseases as well as in the mechanism of circulatory disorders.
Download or read book Microcirculation written by Maria Dorobantu and published by Springer Nature. This book was released on 2019-11-04 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference book of coronary microcirculation broadly covers theoretical aspects, clinical cases and therapeutic considerations from an innovative perspective. Topics covered include: ischemic heart disease, silent cerebral damage, heart failure, left ventricular hypertrophy arrhythmias, and cerebral and renal microcirculation. Microcirculation: From Bench to Bedside underlines the clinical importance of addressing coronary microcirculation with relevant clinical examples that are often encountered by practitioners. It therefore provides a critical resource on microcirculation for both specialist and non-specialist practitioners.
Download or read book Microcirculation in Circulatory Disorders written by Hisao Manabe and published by . This book was released on 1988-01-01 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowadays, a knowledge of the microcirculation has become essential for a thorough understanding of the mechanism of organ disorders. In Osaka on 1-2 August 1987, a conference on microcirculatory disorders was held as the Satellite Symposium of the Fourth World Congress for Microcircu lation and to mark the tenth anniversary of the National Cardiovascular Center of Japan. It was an opportune time for such a meeting, which drew the attendance of biomedical scientists and clinicians from many different parts of the world. The pathophysiological significance of the microcirculation in ischemia and disease was elucidated with lively pre sentations dealing with both experimental and clinical aspects. The present volume summarizes the proceedings of that symposium. A review is made of recent advances in microvascular disorders, follow ing which cerebral, myocardial, and peripheral tissue ischemia, multiple organ failure, gastroenterological disorders, and methodology are closely examined. We wish to express our thanks to our contributors, who obliged us by submitting their manuscripts within the time limit. We are grateful to Prof. Masaharu Tsuchiya, President of the Fourth World Congress for Microcirculation, who generously allowed these proceedings to be pub lished. We would also like to thank Dr. Syoten Oka, Dr. Hiroshi Abe, Dr. Teruo Omae, Prof. Takenobu Kamada, Dr. Hiroshi Sakakibara, Dr. Tohru Sawada, and other members of the organizing committee. We are also obliged to Drs. Nobuko Tsushima, Nobuhiro Sato, Hiroaki Naritomi, and Ryu Nakayama for organizing the session symposia."
Download or read book Microcirculation in Cardiovascular Diseases written by Enrico Agabiti-Rosei and published by Springer Nature. This book was released on 2020-10-03 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an extensive review of the most recent data on the pathophysiological role of structural and functional alterations in the microcirculation, particularly focusing on hypertension and diabetes. It covers several relevant and innovative aspects, including the possible mechanisms involved in the development of microvascular remodeling and rarefaction, the technical approaches available for the detection of microvascular alterations, including non-invasive evaluations, the prognostic role of changes in small resistance artery structure, the possibility of preventing or regressing such alterations with appropriate treatment, and the potential clinical advantages of such intervention. A number of innovative areas of research are considered, including the role of the immune system, inflammation and oxidative stress in the development of microvascular alterations. Lastly, it examines the availability of recent non-invasive methods for the evaluation of small resistance artery morphology in the retina, which in the near future may provide a useful tool for the stratification of cardiovascular risk and even for clinical decisions regarding drug treatment, thus providing physicians with a clinically relevant instrument for improving and optimizing the management of hypertensive and diabetic patients. The book provides valuable, clinically relevant information for specialists (cardiology, internal medicine, and endocrinology) and general practitioners, and also offers novel and stimulating data to basic and clinical researchers.
Download or read book The Microcirculation in Clinical Medicine written by Roe Wells and published by . This book was released on 1973 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Pathophysiology of the Microcirculation written by Nicholas A. Mortillaro and published by CRC Press. This book was released on 1994-02-28 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to the pathophysiology of the microcirculation, an intensely studied area of the circulatory system. Featuring contributions from 29 top investigators in the field, the book begins with an introduction to the general structure of the normal microvascular system, with special emphasis on the characteristics of blood vessel segments collectively comprising the system. Significant areas covered in the book include angiogenesis, neoplasias, hypertension, shock, ischemia/reperfusion, diabetes, immunologic injury, and thermal injury. It also covers the effects of aging and environmental factors on the microcirculation-topics not often examined in depth. More than 80 figures and tables illustrate key concepts throughout the book.
Download or read book Basic and Clinical Understanding of Microcirculation written by Kaneez Fatima Shad and published by BoD – Books on Demand. This book was released on 2020-07-22 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microcirculation is key to providing enough nutrition and oxygen from head to toe. This is possible only through an extensive network of blood vessels spread around the body. Effect of microcirculation abnormalities stretch beyond one’s comprehension. The effects could be felt at any age, from the foetal life to the adulthood. The chapters present in this book describe how these abnormalities could lead to diseases such as atherosclerosis, thrombosis, diabetes, hypertension. Disorders of microcirculation could be related to the structural and/or functional damage to the inner lining of the blood vessels. Early identification of these disorders could benefit many ailments including cardiovascular and cerebrovascular diseases such as heart attack and stroke.
Download or read book Microcirculation as Related to Shock written by David Shepro and published by Elsevier. This book was released on 2012-12-02 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microcirculation as Related to Shock contains the proceedings of the 1967 Conference on the Microcirculation as Related to Shock held at Boston University. Contributors address reduced blood flow in the microcirculation and microcirculatory hypoperfusion as the focal point of shock. They also review significant progress in shock research, basic cardiovascular physiology, and cognate interdisciplinary fields. This volume is organized into four sections encompassing 26 chapters and begins with an overview of organs and systems involved in shock, including splanchnic circulation, regulatory mechanisms in shock, and microcirculatory studies in hypotension. The next chapters explore the causative factors that produce the state of low blood flow as found in shock, and whether microcirculatory hypoperfusion in humans can be prevented and treated. The book also discusses whether microcirculatory hypoperfusion can be measured in the patient and concludes with an assessment of promising avenues for further research, emphasizing the measurement of blood viscosity, shear stress, and rheological factors as indices of the degree of hypotension. This book is a valuable source of information for physiologists, biologists, and pathologists, as well as those involved in the medical sciences.
Download or read book Inflammation and the Microcirculation written by D. Neil Granger and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References
Download or read book Clinically Applied Microcirculation Research written by John Barker and published by Routledge. This book was released on 2019-06-04 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1995: Clinically Applied Microcirculation Research combines state-of-the-art microcirculation technology with present and potential applications in clinical medicine. This comprehensive guide unites the expertise of clinicians and basic researchers from around the world. Many of the chapters are authored by scientist/physician teams. The book provides a broad overview of how microcirculation is involved in clinical research. This is also a valuable reference source for both the history of and latest developments in microcirculation research.
Download or read book Microcirculation written by Ronald F. Tuma and published by Academic Press. This book was released on 2011-04-28 with total page 1000 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference is a volume in the Handbook of Physiology, co-published with The American Physiological Society. Growth in knowledge about the microcirculation has been explosive with the field becoming fragmented into numerous subdisciplines and subspecialties. This volume pulls all of the critical information into one volume. Meticulously edited and reviewed. Benefit: Provides investigators a unique tool to explore the significance of their findings in the context of other aspects of the microcirculation. In this way, the updated edition has a direct role in helping to develop new pathways of research and scholarship Highlights the explosive growth in knowledge about the microcirculation including the biology of nitric oxide synthase (NOS), endothelial cell signaling, angiogenesis, cell adhesion molecules, lymphocyte trafficking, ion channels and receptors, and propagated vasomotor responses. Benefit: Microcirculatory biology has become fragmented into numerous sub-disciplines and subspecialties, and these reference reintegrates the information in one volume
Download or read book Regulation of Tissue Oxygenation Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Download or read book Microvascular Mechanics written by Jen-Shih Lee and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: . . . we do not know a truth without knowing its cause. Aristotle Perhaps the greatest hope that may be entertained for a scientific work, whether experimental or theoretical, is that it leads to new thoughts and new avenues of investigation on the part of its readers. In microvascular mechanics, the interplay of rheology, anatomy, and cellular and organ function has only just begun to be addressed. To understand the operational behavior of microcirculation, there is a need to integrate studies at the cellular or molecu lar level with a quantitative, biomechanical description of the circulatory system. The symposium entitled "Frontiers in Cardiopulmonary Mechanics" held in June 1988 at the University of Virginia was intended to provide a fundamental approach to the description of the circulation from the per spective of microvascular mechanics and to examine new methodology that may advance this effort. This book arose out ofthe work presented at the symposium. Aristotle expressed well the need to pursue the causes of a phenomenon in order to achieve a truthful understanding of its nature. In this spirit has each of the quantitative sciences progressed, and in this spirit we hope that this book will provide some understanding of the microvascular events and bio mechanical mechanisms underlying the behavior of circulation in general, and of pulmonary and skeletal muscle microcirculation in particular. The integrated treatment of pulmonary and systemic microcirculation provided here is intended to encourage the cross-fertilization of these two research fields.
Download or read book Clinical Investigation of the Microcirculation written by John E. Tooke and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1628 William Harvey published his discovery of the existence of the microcirculation which he deduced from careful anatomical and physiological study. Thirty-three years later, Malpighi confirmed the presence of capillaries through direct microscopical observation. Subsequent scientific advance has been slow, and in view of the fact that microvascular in the genesis and expression of many pathophysiology may be implicated diseases, our know ledge of human microvascular function is surprisingly limited. This ignorance attests to the difficulty of studying something that is both minute and inaccessible without disturbing the quantity that is being measured. In the last fifteen years, however, direct techniques have been developed for studying human microvascular pressure, flow and permeability. These methods have provided new insights into human microvascular function in health and disease. At the same time there has been a steady growth of new indirect techniques based on a w ide range of physical principles that reflect some or other aspect of microvascular function.
Download or read book Molecular Basis for Microcirculatory Disorders written by Geert W. Schmid-Schönbein and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: A large number of cardiovascular diseases are accompanied by inflammation. This volume on the molecular basis of microcirculatory disorders gives a comprehensive summary of key steps in the inflammatory cascade. Leading investigators present a state-of-the-art analysis of the molecular determinants of leukocyte-endothelial cell adhesion, mechanotransduction in endothelial and inflammatory cells, mechanisms of cell activation, microvascular apoptosis with applications to ischemia-reperfusion in the brain, the heart and in venous disease, diabetes and hypertension. The book provides the latest thinking in these important cardiovascular problems, with the most contemporary literature and a look at the increasingly complex events during inflammation. Molecular biology tools, microvascular and modern bioengineering analysis are seamlessly integrated into the analysis of clinical problems. The book helps not only newcomers to gain entry into the interesting problems associated with microvascular disorders, but lays the foundation for the design of new therapeutic interventions.
Download or read book Organ Microcirculation written by H. Ishii and published by Springer Science & Business Media. This book was released on 2006-03-16 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of microcirculation means not only the assembly of small vessels-those of less than 100 um in diameter, but also its functional circulatory and metabolic units. Its principal function is to permit the transfer of substances between the tissues and the circulation, making it a fundamental factor in disease processes, including the spread of cancer, delayed healing, circulatory shock, and complications of diabetes . Organ Microcirculation: A Gateway to Diagnostic and Therapeutic Interventions covers the latest developments in nano-biotechnology for microvascular interventions, gastroduodenal microcirculation and disease, liver microvascular research, cell adhesion and traffic in micmcirculation, and the sensing and bioregulation of gaseous molecules in microcirculation . It provides invaluable information for those engaged in microvascular research in the fields of pharmacology, physiology, gastroenterology, and bioengineering.
Download or read book Microcirculatory Disorders in the Heart and Brain written by Hideyuki Niimi and published by . This book was released on 1991 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt:
