Download or read book Microbicides for Prevention of HIV Infection written by Jeremy Nuttall and published by Springer. This book was released on 2014-09-06 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.
Download or read book Drug Delivery and Development of Anti HIV Microbicides written by José das Neves and published by CRC Press. This book was released on 2014-10-16 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: The worldwide impact of HIV/AIDS is well recognized. This book provides for the first time a thorough and critical overview of current aspects, recent developments, and trends in the formulation and drug delivery concerning anti-HIV microbicides by leading scientists in the field. Additionally, pertinent regulatory aspects and socioeconomical issues related to the subject are discussed. In the absence of a cure, prophylaxis represents a cornerstone in the battle against infection. One promising strategy comprises the use around the time of sexual intercourse of vaginal/rectal products containing antiviral compounds, termed microbicides. It is now recognized that specific development of drug dosage forms and/or drug delivery systems is an indispensable aspect for the success of microbicides. Different groups strived over the last decade to optimize the biophysical and technological performance of traditional dosage forms (gels, tablets, and suppositories) to fulfill the specificities of microbicides use, without neglecting users’ preferences and affordability issues. Moreover, new formulation approaches, such as vaginal rings and films, nanotechnology-based systems, stimuli-sensitive formulations, targeted drug delivery systems, among others have been proposed and are currently undergoing pre-clinical or even clinical testing.
Download or read book HIV Prevention written by Kenneth H. Mayer and published by Academic Press. This book was released on 2009-03-13 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV/AIDS continues to be the pandemic of our times and there has not been a comprehensive medically based AIDS prevention book published in the last 5 years. It is estimated that 36 to 45 million people including 2-3 million children already are infected worldwide and an additional 4-7 million more are infected each year. There are about 6,000 new infections daily and about 12 million AIDS orphans. People receiving AIDS treatments feel well and have no detectable viral load, but still can infect others. And even when a vaccine is found, it will take many years before it can be administered across the developing world. * Discusses all aspects of AIDS prevention, from epidemiology, molecular immunology and virology to the principles of broad-based public health prevention interventions. * Special focus on the array of interventions that have been proven effective through rigorous study * Identifies new trends in HIV/AID epidemiology and their impact on creating and implementing prevention interventions * Incorporates virology, biology, infectious diseases, vaccinology, microbicides and research methodologies into AIDS prevention
Download or read book Disease Control Priorities Third Edition Volume 6 written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Download or read book Biomedical Advances in HIV Prevention written by Lisa A. Eaton and published by Springer Science & Business Media. This book was released on 2013-10-08 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Advances in HIV Prevention: Social and Behavioral Perspectives Lisa A. Eaton and Seth C. Kalichman, editors Three decades into the epidemic, a great deal is known about HIV and its transmission, more people are living with the disease, and the virus is no longer seen as a death sentence. But new people continue to be infected with HIV each year, making prevention strategies that are medically effective and behaviorally engaging as urgent a priority as ever. Biomedical Advances in HIV Prevention: Social and Behavioral Perspectives assembles the latest improvements, barriers to implementation, and possibilities for--and challenges to--future progress. Innovations such as pre-exposure prophylaxis (antiretroviral regimens for the high-risk uninfected) and treatment as prevention (early use of ART to reduce infectiousness of new patients) are examined, as are current findings on ongoing prevention and treatment concerns. Contributors illuminate the complex realities entailing adherence, pointing out technological, behavioral, and cultural roadblocks as well as opportunities to significantly reduce infection rates. Detailed up-to-the-minute coverage includes: Prevention services for persons living with HIV Adherence to HIV treatment as prevention and pre-exposure prophylaxis Advocating for rectal microbicides and safe lubricants Mental health and substance use in the scale-up of HIV prevention Risk compensation in response to HIV prevention Implementing biomedical HIV prevention advances: reports from South Africa, Uganda, Australia, Thailand, United States, Ecuador, and Peru Researchers, practitioners, and policy makers working in the fields of HIV/AIDS and public health will look toward Biomedical Advances in HIV Prevention: Social and Behavioral Perspectives as both a means for developing and assessing current programs and a blueprint for the next generation of prevention efforts.
Download or read book Microbicides for HIV prevention written by Joint United Nations Programme on HIV/AIDS. and published by . This book was released on 1998 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book No Time to Lose written by Institute of Medicine and published by National Academies Press. This book was released on 2001-03-02 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United States has spent two productive decades implementing a variety of prevention programs. While these efforts have slowed the rate of infection, challenges remain. The United States must refocus its efforts to contain the spread of HIV and AIDS in a way that would prevent as many new HIV infections as possible. No Time to Lose presents the Institute of Medicine's framework for a national prevention strategy.
Download or read book Bioethical Challenges in New Hiv Prevention Technologies written by Calvin Gwandure and published by Xlibris Corporation. This book was released on 2018-05-23 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ruth Gwandure earned her master of science degree in medicine (bioethics and law) from the University of the Witwatersrand, South Africa. Her research and consulting fields include bioethics, health law, environmental bioethics, research ethics, HIV and AIDS, ethics and law, clinical ethics, and HIV counselling and testing in schools. Calvin Gwandure has a PhD in psychology. He graduated from Nelson Mandela University, South Africa. His research and consulting fields include HIV and AIDS prevention, new HIV prevention technologies, HIV risk behavior, and group behavior. Clinical trials on HIV and AIDS prevention face challenges associated with infection of participants with HIV and sexually transmitted infections. Participants also experience adverse events associated with voluntary medical male circumcision and the use of microbicides and vaccines in clinical trials. The results obtained from clinical trials investigating the efficacy of microbicides and vaccines in preventing HIV infection are disappointing, but there is hope that one day a breakthrough could be made. Clinical trials on voluntary medical male circumcision and preexposure prophylaxis have shown positive results that warranted approval by the US Food and Drug Administration (FDA) and the World Health Organization (WHO). The major challenge experienced in new HIV prevention clinical trials that are underway and in approved interventions that are being scaled up apparently relates to HIV incidence that threatens the social value and scientific validity of the interventions. Paradoxically, the clinical trials and scale-up interventions have become the new sources of HIV infection although the hypothesized benefit to be realized in the end is conceptualized as outweighing the current risks involved.
Download or read book Trends in Basic and Therapeutic Options in HIV Infection written by Bartholomew Ibeh and published by BoD – Books on Demand. This book was released on 2015-09-02 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has seen several changes in HIV prevention, transmission and therapeutic interventions to end the scourge. This book is a collection of expert assays on various aspects of HIV prevention, bioresource deployment, microbicides, host antiviral proteins, antiviral drug responses and novel treatment strategies for which there is evident need for scientific focus and review of the current trend. A visible objective of the book is to provide a wider readership of scientist, clinicians, social workers/HIV caregivers, immunologist, postgraduate students, trainers and vaccine developers an informative and multidisciplinary approach to HIV treatment and intervention strategy by presenting current trends in the development of therapeutic options and its attendant challenges. Practical and informative, the book provides state-of-the-art information on dynamics of HIV distribution, transmission, therapeutic measures and functional cure.
Download or read book Women and Health written by Marlene B. Goldman and published by Academic Press. This book was released on 2012-12-31 with total page 1616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Women and Health is a comprehensive reference that addresses health issues affecting women of all ages — from adolescence through maturity. It goes far beyond other books on this topic, which concentrate only on reproductive health, and has a truly international perspective. It covers key issues ranging from osteoporosis to breast cancer and other cancers, domestic violence, sexually transmitted diseases, occupational hazards, eating disorders, heart disease and other chronic illnesses, substance abuse, and societal and behavioral influences on health. In this second edition of Women and Health, chapters thoughtfully explore the current state of women’s health and health care, including the influences of sex and gender on the occurrence of a wide variety of diseases and conditions. All chapters have been extensively updated and emphasize the epidemiology of the condition — the etiology, occurrence, primary and secondary prevention (screening), risk factors, surveillance, changing trends over time, and critical analysis of the diagnostic and treatment options and controversies. Treatment sections in each chapter have been expanded to create a stronger dialogue between epidemiologists and women's health practitioners. Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of women’s health issues, as opposed to searching through thousands of journal articles Provides a common language for epidemiologists, public health practitioners, and women’s health specialists to discuss the behavioral, cultural, and biological determinants of women’s health Researchers and medical specialists will learn how the gender-specific risks and features of one organ system’s diseases affect the health of other organ systems For example: Hormone replacement therapy used to treat imbalance within the endocrine system is also being used to prevent and treat cardiovascular disease; Drugs developed for type 2 diabetes are now being used in chemoprevention Orients the non-gerontologist about the importance of considering the entire life cycle of women within research designs and treatment plans Professors teaching courses in women’s health will use slides and additional materials to structure lectures/courses; students will use slides as a unique resource to study for exams
Download or read book Cutaneous Laser Surgery written by Mitchel P. Goldman and published by Mosby. This book was released on 1999 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stay on the cutting edge of laser technology with state-of-the-art summaries on all cutaneous laser systems, including carbondioxide, argon-pumped, tunable dye, copper vapor, ruby, flashlamp-pumped pulsed dye, Nd:YAG, and photoderm. CUTANEOUS LASER SURGERY provides an unbiased review of each system, listing the pros and cons of each for use on various types of lesions. You'll also find new information on laser resurfacing, photodynamic therapy, and hair removal. * Includes thorough discussions of all laser systems * Provides treatment options for pigmented lesions, vascular lesions, tattoos and laser resurfacing all in one book * Guides you to the appropriate choice of procedure for each particular lesion * Gives you an unbiased view of each laser system * Illustrates techniques with clear before and after photography * Provides step-by-step guidance through procedures * Includes patient consent forms and patient handouts to save you valuable time
Download or read book Fundamentals of Sexually Transmitted Infections written by Zekayi Kutlubay and published by BoD – Books on Demand. This book was released on 2017-09-06 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook includes the recent progresses and scientific knowledge from the leading experts in different approaches to control, diagnosis, and management depending on resources and facilities available. This book has been written by our colleagues from all over the world. This book is divided into six sections. Each section supplies particularly sexually transmitted infections, diagnostics, microorganism types, pathogenesis, and treatment options. Essential points in publishing this book are to improve our knowledge about sexually transmitted infections and new treatment modalities. One chapter of the book is devoted to viral infections and their treatment. We think that this textbook will serve as a comprehensive guide to many physicians dealing with sexually transmitted infections in their clinical practice. It will hopefully be a precious source for dermatologists, educators, other physicians, and medical students.
Download or read book HIV Prevention in the Third Decade written by and published by . This book was released on 2005 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book HIV AIDS Global Frontiers in Prevention Intervention written by Cynthia Pope and published by Routledge. This book was released on 2014-06-11 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV/AIDS: Global Frontiers in Prevention/Intervention provides a comprehensive overview of the global HIV/AIDS epidemic. The unique anthology addresses cutting-edge issues in HIV/AIDS research, policymaking, and advocacy. Key features include: · Nine original essays from leading scholars in public health, epidemiology, and social and behavioral sciences · Comprehensive information for individuals with varying degrees of knowledge, particularly regarding methodological and theoretical perspectives · A look into the future progression of HIV transmission and scholarly research HIV/AIDS: Global Frontiers in Prevention/Intervention is will serve as a precious resource as a textbook and reference for the university classroom, libraries, and researchers
Download or read book Methodological Challenges in Biomedical HIV Prevention Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2008-06-13 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: The number of people infected with HIV or living with AIDS is increasing at unprecedented rates as various scientists, organizations, and institutions search for innovative solutions to combating and preventing the disease. At the request of the Bill & Melinda Gates Foundation, Methodological Challenges in Biomedical HIV Prevention Trials addresses methodological challenges in late-stage nonvaccine biomedical HIV prevention trials with a specific focus on microbicide and pre-exposure prophylaxis trials. This book recommends a number of ways to improve the design, monitoring, and analysis of late-stage clinical trials that evaluate nonvaccine biomedical interventions. The objectives include identifying a beneficial method of intervention, enhancing quantification of the impact, properly assessing the effects of using such an intervention, and reducing biases that can lead to false positive trial results. According to Methodological Challenges in Biomedical HIV Prevention Trials, the need to identify a range of effective, practical, and affordable preventive strategies is critical. Although a large number of promising new HIV prevention strategies and products are currently being tested in late-stage clinical trials, these trials face a myriad of methodological challenges that slow the pace of research and limit the ability to identify and fully evaluate effective biomedical interventions.
Download or read book HIV written by Frederic Bushman and published by Cold Spring Harbor Perspective. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The basic biology of the HIV virus provides a model for a more general understanding of retroviruses, and the worldwide epidemic of AIDS makes research into the disease process and potential therapies among the most critical in biomedical science. This book explores work on the molecular biology of HIV, host-virus interactions, host immune responses, HIV transmission, and more.
Download or read book Preventing and Mitigating AIDS in Sub Saharan Africa written by National Research Council and published by National Academies Press. This book was released on 1996-03-28 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: The AIDS epidemic in Sub-Saharan Africa continues to affect all facets of life throughout the subcontinent. Deaths related to AIDS have driven down the life expectancy rate of residents in Zambia, Kenya, and Uganda with far-reaching implications. This book details the current state of the AIDS epidemic in Africa and what is known about the behaviors that contribute to the transmission of the HIV infection. It lays out what research is needed and what is necessary to design more effective prevention programs.
