Download or read book Microbial Pathogenesis written by Uday Kishore and published by Springer Nature. This book was released on 2021-10-18 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book updates in detail the microbial pathogenesis of various important pathogens, including HIV-1, MERS, SARS-CoV-2, Mycobacterium and Plasmodium. There is also a general discussion of the innate and adaptive immune responses against primary and opportunistic infections. The overall purpose of the book is to aid in the development of anti-viral and anti-microbial targets.
Download or read book Microbial Pathogenesis Infection and Immunity written by Uday Kishore and published by Springer. This book was released on 2013-12-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book starts with dissecting mechanisms underlying viral immune evasion via exploiting the host complement system by vaccinia virus, and by modulating the type 1 interferon response by RNA viruses. Yet another chapter looks into how viroporins expressed by different families of viruses causing influenza A virus, SARS, hepatitis C and HIV interact with several cellular pathways. Understanding of these mechanisms can aid the development of novel potential anti‐viral targets. The chapter on tuberculosis discusses the emerging importance of the innate immune mechanisms against Mycobacterium tuberculosis infection and latency. This book has a strong focus on fungal pathogenesis and immunity, starting with virulence and host factors that attain great importance in candidiasis and associated escape tricks of seriously opportunistic fungi. Two chapters on Aspergillus fumigatus elaborate on the pathogenic mechanisms: first discussing A. fumigatus‐airway epithelium interaction, followed by fungal and host factors that are paramount in the development of allergic and invasive aspergillosis. In the subsequent chapter, there is a general discussion on the innate and adaptive immune responses against primary and opportunistic fungal pathogens.
Download or read book Unifying Microbial Mechanisms written by Michael F. Cole and published by Garland Science. This book was released on 2019-09-09 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial pathogenesis is the study of the mechanisms by which microbes (bacteria, viruses, protozoa, and multicellular parasites) cause infectious disease and make their hosts (humans) ill. Bacterial infections we thought were easily treatable are again a huge cause for concern with the well-publicized rise of antibiotic resistance. There are very few effective antiviral drugs and we live with the threat of epidemics such as bird flu and the outbreaks of viruses such the recent (and ongoing) Ebola crisis. Parasitic diseases such as malaria continue to pose a heavy burden in the developing world and with climate change could spread into the developed world. There is therefore an urgent need to understand microbial mechanisms, with research programmes and university courses dedicated to the subject
Download or read book Vaccinology written by Gregg N. Milligan and published by John Wiley & Sons. This book was released on 2015-02-16 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes. Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.
Download or read book Janeway s Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bacteria A Very Short Introduction written by Sebastian G. B. Amyes and published by OUP Oxford. This book was released on 2013-05-30 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteria form a fundamental branch of life. They are the oldest forms of life as we know it, and they are still the most prolific living organisms. They inhabit every part of the Earth's surface, its ocean depths, and even terrains such as boiling hot springs. They are most familiar as agents of disease, but benign bacteria are critical to the recycling of elements and all ecology, as well as to human health. In this Very Short Introduction, Sebastian Amyes explores the nature of bacteria, their origin and evolution, bacteria in the environment, and bacteria and disease. In looking at our efforts to manage co-evolving bacteria, he also considers the challenges of resistance to antibiotics. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Download or read book Bacterial Pathogenesis written by and published by Academic Press. This book was released on 1998-07-01 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. Focuses on the methods most useful for the microbiologist interested in the way in which bacteria cause disease Includes section devoted to 'Approaches to characterising pathogenic mechanisms' by Stanley Falkow Covers safety aspects, detection, identification and speciation Includes techniques for the study of host interactions and reactions in animals and plants Describes biochemical and molecular genetic approaches Essential methods for gene expression and analysis Covers strategies and problems for disease control
Download or read book GI Microbiota and Regulation of the Immune System written by Gary B. Huffnagle and published by Springer Science & Business Media. This book was released on 2008-08-21 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers current trends in the investigation of GI microbiota. It examines the relationship between the microbiota and the immune system from a variety of angles.
Download or read book Encyclopedia of Infection and Immunity written by and published by Elsevier. This book was released on 2022-04-22 with total page 2112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Infection and Immunity provides new insights into the interactions between bacteria, fungi, parasites and their hosts. Specific areas of interest include host cellular and immune response to microbes, molecular mechanisms of action of beneficial microbes or host-associated microbial communities, microbial pathogenesis, virulence factors, experimental models of infection, host resistance or susceptibility, and the generation of innate and adaptive immune responses. Comprised of over 200 chapters written and edited by leading experts in the field, this book will serve as a key resource for students, researchers, academics and industry practitioners in the fields of microbiology, immunology, and infectious diseases. More than 100 years after Robert Koch and Louis Pasteur established the microbial etiology of communicable diseases, the field of microbiology is experiencing a second period of rapid growth and expansion, driven by the realization that changes in host-associated microbial communities might be at the root of a broad spectrum of noncommunicable human diseases. These advances follow on the heels of recent progress in high-throughput sequencing technology, which has provided a wealth of information on the human microbiome and its physiological potential. Offers a contemporary review of current infection and immunity research, and insights into the future direction of the field Meticulously researched and cross-referenced to allow students, researchers and professionals to find relevant information quickly and easily Includes chapters written by academics and practitioners from various fields and regions, ensuring that the knowledge within is easily understood by, and applicable to, a large audience
Download or read book Treating Infectious Diseases in a Microbial World written by National Research Council and published by National Academies Press. This book was released on 2006-01-03 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Download or read book Critical Needs and Gaps in Understanding Prevention Amelioration and Resolution of Lyme and Other Tick Borne Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A single tick bite can have debilitating consequences. Lyme disease is the most common disease carried by ticks in the United States, and the number of those afflicted is growing steadily. If left untreated, the diseases carried by ticks-known as tick-borne diseases-can cause severe pain, fatigue, neurological problems, and other serious health problems. The Institute of Medicine held a workshop October 11-12, 2010, to examine the state of the science in Lyme disease and other tick-borne diseases.
Download or read book Microbial pathogenesis and immune response written by Edwin W. Ades and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ending the War Metaphor written by Institute of Medicine and published by National Academies Press. This book was released on 2006-07-09 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases have existed longer than us, as long as us, or are relatively newer than us. It may be the case that a disease has existed for many, many years but has only recently begun affecting humans. At the turn of the century the number of deaths caused by infections in the United States had been falling steadily but since the '80s has seen an increase. In the past 30 years alone 37 new pathogens have been identified as human disease threats and 12% of known human pathogens have been classified as either emerging or remerging. Whatever the story, there is currently a "war" on infectious diseases. This war is simply the systematic search for the microbial "cause" of each disease, followed by the development of antimicrobial therapies. The "war" on infectious diseases, however, must be revisited in order to develop a more realistic and detailed picture of the dynamic interactions among and between host organisms and their diverse populations of microbes. Only a fraction of these microbes are pathogens. Thus, in order to explore the crafting of a new metaphor for host-microbe relationships, and to consider how such a new perspective might inform and prioritize biomedical research, the Forum on Microbial Threats of the Institute of Medicine (IOM) convened the workshop, Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe Relationship on March 16-17, 2005. Workshop participants examined knowledge and approaches to learning about the bacterial inhabitants of the human gut, the best known host-microbe system, as well as findings from studies of microbial communities associated with other mammals, fish, plants, soil, and insects. The perspective adopted by this workshop is one that recognizes the breadth and diversity of host-microbe relationships beyond those relative few that result in overt disease. Included in this summary are the reports and papers of individuals participating in the Forum as well as the views of the editors.
Download or read book Medical Microbiology written by David Greenwood and published by . This book was released on 2002 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is divided into six sections: microbial biology; infection and immunity; bacterial pathogens and associated diseases; viral pathogens and associated diseases; fungal pathogens and parasitic infections; and diagnosis, treatment and control of infection. The major portion gives a o rganism-based systematic coverage of microbiology. Each organism is considered under a standard set of headings: description; pathogenesis; clinical features; laboratory diagnosis; treatment; and epidemiology. The section on immunology covers that part of the subject that is of direct relevance to the understanding of microbial infection.
Download or read book Medical Microbiology E Book written by David Greenwood and published by Elsevier Health Sciences. This book was released on 2012-07-17 with total page 795 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical microbiology concerns the nature, distribution and activities of microbes and how they impact on health and wellbeing, most particularly as agents of infection. Infections remain a major global cause of mortality and in most hospitals around one in ten of those admitted will suffer from an infection acquired during their stay. The evolution of microbes presents a massive challenge to modern medicine and public health. The constant changes in viruses such as influenza, HIV, tuberculosis, malaria and SARS demand vigilance and insight into the underlying process. Building on the huge success of previous editions, Medical Microbiology 18/e will inform and inspire a new generation of readers. Now fully revised and updated, initial sections cover the basic biology of microbes, infection and immunity and are followed by a systematic review of infective agents, their associated diseases and their control. A final integrating section addresses the essential principles of diagnosis, treatment and management. An unrivalled collection of international contributors continues to ensure the relevance of the book worldwide and complementary access to the complete online version on Student Consult further enhances the learning experience. Medical Microbiology is explicitly geared to clinical practice and is an ideal textbook for medical and biomedical students and specialist trainees. It will also prove invaluable to medical laboratory scientists and all other busy professionals who require a clear, current and most trusted guide to this fascinating field.
Download or read book Mims Pathogenesis of Infectious Disease written by Anthony A. Nash and published by Academic Press. This book was released on 2013-10-22 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: The newly revised edition of this work provides an up-to-date description of the mechanisms of infection and disease production in a clear and logical manner. Dealing in an integrated manner with all microorganisms, the factors common to all infectious diseases are set out. Molecular biology, pathology, and immunology are brought together to explain how an infectious agent causes disease, and how the body reacts to it. Attachment to and entry of microorganisms Events occurring immediately after entry The encounter of the microbe with the phagocytic cell The spread of microbes through the body The immune response to infection Microbial strategies in relation to the immune response Mechanisms of cell and tissue damage Recovery from infection Failure to eliminate the microbe Host and microbial factors influencing susceptibility Vaccines
