Download or read book Methodology for Family Studies of Genetic Factors written by World Health Organization. Scientific Group on Methodology for Family Studies of Genetic Factors and published by . This book was released on 1971 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Methodology For Family Studies on Genetic Factors written by and published by . This book was released on 1971 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Methodology for Family Studies of Genetic Factors written by and published by . This book was released on 1971 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Methodology for Family Studies of Genetic Factors written by WHO Staff and published by . This book was released on 1971-01-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Methodology for Genetic Studies of Twins and Families written by M. Neale and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few would dispute the truth of the statement `People are Different', but there is much controversy over why. This book authoritatively explains the methods used to understand human variation, and extends them far beyond the primary `nature or nurture' question. After chapters on basic statistics, biometrical genetics, matrix algebra and path analysis, there is a state-of-the-art account of how to fit genetic models using the LISREL package. The authors explain not only the assumptions of the twin method, but how to test them. The elementary model is expanded to cover sex limitation, sibling interaction, multivariate and longitudinal data, observer ratings, and twin-family studies. Throughout, the methods are illustrated by applications to diverse areas such as obesity, major depression, alcohol comsumption, delinquency, allergies, and common fears.
Download or read book The Oxford Handbook of Quantitative Methods Vol 2 Statistical Analysis written by Todd D. Little and published by Oxford University Press. This book was released on 2013-02-01 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research today demands the application of sophisticated and powerful research tools. Fulfilling this need, The Oxford Handbook of Quantitative Methods is the complete tool box to deliver the most valid and generalizable answers to todays complex research questions. It is a one-stop source for learning and reviewing current best-practices in quantitative methods as practiced in the social, behavioral, and educational sciences. Comprising two volumes, this handbook covers a wealth of topics related to quantitative research methods. It begins with essential philosophical and ethical issues related to science and quantitative research. It then addresses core measurement topics before delving into the design of studies. Principal issues related to modern estimation and mathematical modeling are also detailed. Topics in the handbook then segway into the realm of statistical inference and modeling with chapters dedicated to classical approaches as well as modern latent variable approaches. Numerous chapters associated with longitudinal data and more specialized techniques round out this broad selection of topics. Comprehensive, authoritative, and user-friendly, this two-volume set will be an indispensable resource for serious researchers across the social, behavioral, and educational sciences.
Download or read book Novel Approaches to the Analysis of Family Data in Genetic Epidemiology written by Xiangqing Sun and published by Frontiers Media SA. This book was released on 2016-08-17 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome-wide association studies (GWAS) for complex disorders with large case-control populations have been performed on hundreds of traits in more than 1200 published studies (http://www.genome.gov/gwastudies/) but the variants detected by GWAS account for little of the heritability of these traits, leading to an increasing interest in using family based designs. While GWAS studies are designed to find common variants with low to moderate attributable risks, family based studies are expected to find rare variants with high attributable risk. Because family-based designs can better control both genetic and environmental background, this study design is robust to heterogeneity and population stratification. Moreover, in family-based analysis, the background genetic variation can be modeled to control the residual variance which could increase the power to identify disease associated rare variants. Analysis of families can also help us gain knowledge about disease transmission and inheritance patterns. Although a family-based design has the advantage of being robust to false positives, novel and powerful methods to analyze families in genetic epidemiology continue to be needed, especially for the interaction between genetic and environmental factors associated with disease. Moreover, with the rapid development of sequencing technology, advances in approaches to the design and analysis of sequencing data in families are also greatly needed. The 11 articles in this book all introduce new methodology and, using family data, substantial new findings are presented in the areas of infectious diseases, diabetes, eye traits, autism spectrum disorder and prostate cancer.
Download or read book The Neurobiological Basis of Suicide written by Yogesh Dwivedi and published by CRC Press. This book was released on 2012-06-25 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Download or read book Methods of Family Research written by Irving E. Sigel and published by Routledge. This book was released on 2014-02-24 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: These companion volumes provide a "behind the scenes" look into the personal experiences of researchers in an effort to eliminate the lack of communication surrounding family research methodology. They show how the researchers achieved their results and why they chose particular methodologies over others. These volumes present more than just findings -- they present the real experiences of the authors in their own styles and personalities, exposing the problems, mistakes, and concerns they experienced during their research projects. Volume I presents the experiences of researchers into typical normative populations. Volume II describes work with clinical, atypical populations.
Download or read book The Oxford Handbook of Hoarding and Acquiring written by Randy O. Frost and published by Oxford Library of Psychology. This book was released on 2014 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hoarding involves the acquisition of and inability to discard large numbers of possessions that clutter the living area of the person collecting them. It becomes a disorder when the behavior causes significant distress or interferes with functioning. Hoarding can interfere with activities of daily living (such as being able to sit in chairs or sleep in a bed), work efficiency, family relationships, as well as health and safety. Hoarding behavior can range from mild to life-threatening. Epidemiological findings suggest that hoarding occurs in 2-6% of the adult population, making it two to three times more common than obsessive-compulsive disorder. The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) now includes Hoarding Disorder as a distinct disorder within the OCD and Related Anxiety Disorders section, creating a demand for information about it. The Oxford Handbook of Hoarding and Acquiring is the first volume to detail the empirical research on hoarding. Including contributions from all of the leading researchers in the field, this comprehensive volume is divided into four sections in addition to introductory and concluding chapters by the editors: Phenomenology, Epidemiology, and Diagnosis; Etiology; Assessment and Intervention; and Hoarding in Special Populations. The summaries of research and clinical interventions contained here clarify the emotional and behavioral features, diagnostic challenges, and nature of the treatment interventions for this new disorder. This handbook will be a critical resource for both practitioners and researchers, including psychiatrists, psychologists, neurologists, epidemiologists, social workers, occupational therapists, and other health and mental health professionals who encounter clients with hoarding problems in their practice and research.
Download or read book The Gene Illusion written by Jay Joseph and published by Algora Publishing. This book was released on 2004 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic factors are increasingly presented as an important influence on psychiatric disorders, personality, intelligence, and various types of socially unacceptable behavior OCo as if that were an unassailable fact, proven by research. Jay JosephOCOs timely,"
Download or read book Twin and Family Studies of Epigenetics written by Shuai Li and published by Academic Press. This book was released on 2021-08-19 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twin and Family Studies of Epigenetics, Volume 27, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, twin and family studies are employed to examine causes of epigenetic variation, the relationship between epigenetic modifications and mental illness, cancers, cardiovascular disease, diabetes, obesity, high blood pressure, and more. Emerging research methods applied in twin and family studies discussed include imaging epigenetics, exposure-specific DNA methylation changes, and unravelling time trends in epigenetic effects. - Offers a practical, interdisciplinary approach across epigenetics, epidemiology and various disease specialties - Applies epigenetic twin and family studies to determine the relationship between epigenetics and mental illness, cancers, cardiovascular disease, diabetes, obesity and high blood pressure, among other diseases and disorders - Features chapter contributions from a wide range of international researchers in the field
Download or read book Emerging Methods in Family Research written by Susan M. McHale and published by Springer Science & Business Media. This book was released on 2013-10-15 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The family can be a model of loving support, a crucible of pathology, or some blend of the two. Across disciplines, it is also the basic unit for studying human relationships, patterns of behavior, and influence on individuals and society. As family structures evolve and challenge previous societal norms, new means are required for understanding their dynamics, and for improving family interventions and policies. Emerging Methods in Family Research details innovative approaches designed to keep researchers apace with the diversity and complexities of today's families. This versatile idea-book offers meaningful new ways to represent multiple forms of diversity in family structure and process, cutting-edge updates to family systems models and measurement methods, and guidance on the research process, from designing projects to analyzing findings. These chapters provide not only new frameworks for basic research on families, but also prime examples of their practical use in intervention and policy studies. Contributors also consider the similarities and differences between the study of individuals and the study of family relationships and systems. Included in the coverage: Use of nonlinear dynamic models to study families as coordinated symbiotic systems. Use of network models for understanding change and diversity in the formal structure of American families. Representing trends and moment-to-moment variability in dyadic and family processes using state-space modeling techniques. Why qualitative and ethnographic methods are essential for understanding family life. Methods in multi-site trials of family-based interventions. Implementing the Multiphase Optimization Strategy (MOST) to analyze the effects of family interventions. Researchers in human development, family studies, clinical and developmental psychology, social psychology, sociology, anthropology, and social welfare as well as public policy researchers will welcome Emerging Methods in Family Research as a resource to inspire novel approaches to studying families.
Download or read book Genes Behavior and the Social Environment written by Institute of Medicine and published by National Academies Press. This book was released on 2006-11-07 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.
Download or read book Special Report written by National Institute of Mental Health (U.S.) and published by . This book was released on 1979 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Models of Madness written by John Read and published by Psychology Press. This book was released on 2004 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Models of Madnessshows that hallucinations and delusions are understandable reactions to life events and circumstances rather than symptoms of a supposed genetic predisposition or biological disturbance. International contributors: * critique the 'medical model' of madness * examine the dominance of the 'illness' approach to understanding madness from historical and economic perspectives * document the role of drug companies * outline the alternative to drug based solutions * identify the urgency and possibility of prevention of madness. Models of Madness promotes a more humane and effective response to treating severely distressed people that will prove essential reading for psychiatrists and clinical psychologists and of great interest to all those who work in the mental health service. This book forms part of the International Society for the Psychological Treatment of Psychoses series edited by Brian Martindale.
Download or read book Genetic Epidemiology written by Melissa A. Austin and published by CABI. This book was released on 2013 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic epidemiology plays a key role in discovering genetic factors influencing health and disease, and in understanding how genes and environmental risk factors interact. There is growing interest in this field within public health, with the goal of translating the results into promoting health and preventing disease in both families and populations. This textbook provides graduate students with a working knowledge of genetic epidemiology research methods. Following an overview of the field, the book reviews key genetic concepts, provides an update on relevant genomic technology, including genome-wide chips and DNA sequencing, and describes methods for assessing the magnitude of genetic influences on diseases and risk factors. The book focuses on research study designs for discovering disease susceptibility genes, including family-based linkage analysis, candidate gene and genome-side association studies, assessing gene-environment interactions and epistasis, studies of Non-Mendelian inheritance, and statistical analyses of data from these studies. Specific applications of each research method are illustrated using a variety of diseases and risk factors relevant to public health, and useful web-based genetic analysis software, human reference panels, and repositories, that can greatly facilitate this work, are described.
