Download or read book Mechanistic Studies in Transition Metal Organic Chemistry written by D. Mead and published by . This book was released on 1970 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanistic Studies on Transition Metal Catalyzed C H Activation Reactions Using Combined Mass Spectrometry and Theoretical Methods written by Gui-Juan Cheng and published by Springer. This book was released on 2017-06-07 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis presents detailed mechanistic studies on a series of important C-H activation reactions using combined computational methods and mass spectrometry experiments. It also provides guidance on the design and improvement of catalysts and ligands. The reactions investigated include: (i) a nitrile-containing template-assisted meta-selective C-H activation, (ii) Pd/mono-N-protected amino acid (MPAA) catalyzed meta-selective C-H activation, (iii) Pd/MPAA catalyzed asymmetric C-H activation reactions, and (iv) Cu-catalyzed sp3 C-H cross-dehydrogenative-coupling reaction. The book reports on a novel dimeric Pd-M (M = Pd or Ag) model for reaction (i), which successfully explains the meta-selectivity observed experimentally. For reaction (ii), with a combined DFT/MS method, the author successfully reveals the roles of MPAA ligands and a new C-H activation mechanism, which accounts for the improved reactivity and high meta-selectivity and opens new avenues for ligand design. She subsequently applies ion-mobility mass spectrometry to capture and separate the [Pd(MPAA)(substrate)] complex at different stages for the first time, providing support for the internal-base model for reaction (iii). Employing DFT studies, she then establishes a chirality relay model that can be widely applied to MPAA-assisted asymmetric C-H activation reactions. Lastly, for reaction (iv) the author conducts detailed computational studies on several plausible pathways for Cu/O2 and Cu/TBHP systems and finds a reliable method for calculating the single electron transfer (SET) process on the basis of benchmark studies.
Download or read book Mechanistic Studies on Transition Metal catalyzed C H Activation Reactions Using Combined Mass Spectrometry and Theoretical Methods written by Gui-Juan Cheng and published by . This book was released on 2017 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis presents detailed mechanistic studies on a series of important C-H activation reactions using combined computational methods and mass spectrometry experiments. It also provides guidance on the design and improvement of catalysts and ligands. The reactions investigated include: (i) a nitrile-containing template-assisted meta-selective C-H activation, (ii) Pd/mono-N-protected amino acid (MPAA) catalyzed meta-selective C-H activation, (iii) Pd/MPAA catalyzed asymmetric C-H activation reactions, and (iv) Cu-catalyzed sp3 C-H cross-dehydrogenative-coupling reaction. The book reports on a novel dimeric Pd-M (M = Pd or Ag) model for reaction (i), which successfully explains the meta-selectivity observed experimentally. For reaction (ii), with a combined DFT/MS method, the author successfully reveals the roles of MPAA ligands and a new C-H activation mechanism, which accounts for the improved reactivity and high meta-selectivity and opens new avenues for ligand design. She subsequently applies ion-mobility mass spectrometry to capture and separate the [Pd(MPAA)(substrate)] complex at different stages for the first time, providing support for the internal-base model for reaction (iii). Employing DFT studies, she then establishes a chirality relay model that can be widely applied to MPAA-assisted asymmetric C-H activation reactions. Lastly, for reaction (iv) the author conducts detailed computational studies on several plausible pathways for Cu/O2 and Cu/TBHP systems and finds a reliable method for calculating the single electron transfer (SET) process on the basis of benchmark studies.
Download or read book Synthetic Structural and Mechanistic Studies in Early Transition Metal and Actinide Chemistry written by Janet E. Nelson and published by . This book was released on 1991 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Organotransition Metal Chemistry A Mechanistic Approach written by Richard Heck and published by Elsevier. This book was released on 2012-12-02 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organotransition Metal Chemistry: A Mechanistic Approach describes a mechanistic approach to the study of the chemistry of organotransition metals. Organotransition metals are discussed in relation to their reactions with specific functional groups or types of compounds rather than by metals. Topics covered include the formation of hydrogen and carbon bonds to transition metals; reactions of transition metal d- and p-bonded derivatives; and addition and elimination reactions of olefinic compounds. This book is comprised of 10 chapters and begins with a historical overview of organotransition metal chemistry, together with the unique chemistry of transition metals and mechanisms of ligand replacements. The following chapters discuss the methods of preparation of hydrido complexes and carbon-transition metal bonds; homogeneous hydrogenation reactions; isomerization, dimerization, oligomerization, and polymerization of olefins; and reactions of dienes, trienes, and tetraenes with transition metal compounds. Transition metal reactions with acetylenes and carbon monoxide as well as organic carbonyl compounds are also examined. This monograph should be of value to organic chemists as well as students and researchers of organic chemistry.
Download or read book Understanding Organometallic Reaction Mechanisms and Catalysis written by Valentin P. Ananikov and published by John Wiley & Sons. This book was released on 2014-08-29 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring and highlighting the new horizons in the studies of reaction mechanisms that open joint application of experimental studies and theoretical calculations is the goal of this book. The latest insights and developments in the mechanistic studies of organometallic reactions and catalytic processes are presented and reviewed. The book adopts a unique approach, exemplifying how to use experiments, spectroscopy measurements, and computational methods to reveal reaction pathways and molecular structures of catalysts, rather than concentrating solely on one discipline. The result is a deeper understanding of the underlying reaction mechanism and correlation between molecular structure and reactivity. The contributions represent a wealth of first-hand information from renowned experts working in these disciplines, covering such topics as activation of small molecules, C-C and C-Heteroatom bonds formation, cross-coupling reactions, carbon dioxide converison, homogeneous and heterogeneous transition metal catalysis and metal-graphene systems. With the knowledge gained, the reader will be able to improve existing reaction protocols and rationally design more efficient catalysts or selective reactions. An indispensable source of information for synthetic, analytical, and theoretical chemists in academia and industry.
Download or read book Synthetic and Mechanistic Studies of Transition Metal Complexes written by John Arthur Broomhead and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles written by Hyung Yoon and published by Springer Nature. This book was released on 2020-09-02 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents Pd- and Ni-catalyzed transformations generating functionalized heterocycles. Transition metal catalysis is at the forefront of synthetic organic chemistry since it offers new and powerful methods to forge carbon–carbon bonds in high atom- and step-economy. In Chapter 1, the author describes a Pd- and Ni-catalyzed cycloisomerization of aryl iodides to alkyl iodides, known as carboiodination. In the context of the Pd-catalyzed variant, the chapter explores the production of enantioenriched carboxamides through diastereoselective Pd-catalyzed carboiodination. It then discusses Ni-catalyzed reactions to generate oxindoles and an enantioselective variant employing a dual ligand system. Chapter 2 introduces readers to a Pd-catalyzed diastereoselective anion-capture cascade. It also examines diastereoselective Pd-catalyzed aryl cyanation to synthesize alkyl nitriles, a method that generates high yields of borylated chromans as a single diastereomer, and highlights its synthetic utility. Lastly, Chapter 3 presents a Pd-catalyzed domino process harnessing carbopalladation, C–H activation and π-system insertion (benzynes and alkynes) to generate spirocycles. It also describes the mechanistic studies performed on these reactions.
Download or read book Theoretical Aspects of Transition Metal Catalysis written by Gernot Frenking and published by Springer Science & Business Media. This book was released on 2005-06-23 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transition metal catalysis belongs to the most important chemical research areas because a ubiquitous number of chemical reactions are catalyzed by transition metal compounds. Many efforts are being made by industry and academia to find new and more efficient catalysts for chemical processes. Transition metals play a prominent role in catalytic research because they have been proven to show an enormous diversity in lowering the activation barrier for chemical reactions. For many years, the search for new catalysts was carried out by trial and error, which was costly and time consuming. The understanding of the mechanism of the catalytic process is often not very advanced because it is difficult to study the elementary steps of the catalysis with experimental techniques. The development of modern quantum chemical methods for calculating possible intermediates and transition states was a breakthrough in gaining an understanding of the reaction pathways of transition metal catalyzed reactions. This volume, organized into eight chapters written by leading scientists in the field, illustrates the progress made during the last decade. The reader will obtain a deep insight into the present state of quantum chemical research in transition metal catalysis.
Download or read book Kinetic and Mechanistic Studies on Some Transition Metal Complexes written by Mohammed Delwar Hussain and published by . This book was released on 1968 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Organometallic Chemistry written by and published by Academic Press. This book was released on 2018-05-21 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Organometallic Chemistry, Volume 69, contains authoritative review articles of world renowned researchers in the field of organometallic chemistry. This longstanding serial is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more, with this release focusing on topics such as C-H Activation Mediated by Main Group Inorganic and Organometallic Compounds, Transition-metals catalyzed intramolecular amination and hydroamination reactions of allenes, Green Fluorescent Protein-like and related organometallic fluorophores, Recent advances in the synthesis of C- S- bonds via metal-catalyzed functionalization of C- H- bonds, Current mechanistic understanding of Co-catalyzed C-H functionalization, and more. The book is ideal for a wide range of researchers involved in organometallic chemistry, including synthetic protocols, mechanistic studies and practical applications. Contains contributions from leading authorities in the field of organometallic chemistry Covers topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more Informs and updates readers on the latest developments in the field Carefully edited to provide easy-to-read material
Download or read book Organic Synthesis by Means of Transition Metal Complexes written by Jiro Tsuji and published by Springer. This book was released on 2011-12-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1970 I wrote a review article for "Topics in Current Chemistry", surveying the general reaction patterns of transition-metal complexes from the standpoint of organic synthesis. The article seems to have evoked wide interest, and I therefore thought it appropriate to treat the subject more comprehensively in the form of a monograph. Organometallic chemistry is a rapidly growing field of intensive research. In this field, the application of organometallic compounds to organic synthesis is an important subject and many unique synthetic methods have been discovered, especially in the last decade. Syntheses using transition-metal com pounds are now in the foreground of organic chemistry. The purpose of this monograph is to give a bird's-eye view of this field to both organic and inorganic chemists through a mechanistic approach. A systematic unification of the voluminous data accumulated in this field is now urgently required. This subject is discussed by classifying various reactions into general patterns and by illustrating them with a limited number of pertinent examples.
Download or read book Kinetic and Mechanistic Studies an the Interaction of Transition Metal Complexes with NO and Related Water Exchange Reactions written by Thorsten Schneppensieper and published by . This book was released on 2001 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanistic Processes in Organometallic Chemistry written by and published by Faraday Discussions. This book was released on 2020-01-02 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organometallic chemistry underpins the majority of homogeneous catalysis, which is used in a range of areas from the multi-tonne-scale synthesis of polymers to the discovery and preparation of high-value molecules, such as pharmaceuticals and agrochemicals. The development and/or optimisation of many of these catalytic applications crucially depends on the discovery and understanding of mechanistic processes in organometallic chemistry. As such, mechanistic investigations have played a key role in the field of organometallic chemistry since its early days, but the recent and rapid growth in transition-metal catalysed organic reactions, where fundamental mechanistic insight is frequently lagging behind synthetic developments, emphasises their contemporary importance. In addition, there have been many significant developments recently in the physical methods that can be used to gain mechanistic understanding in organometallic chemistry (e.g. NMR spectroscopic developments, such as new hyperpolarisation techniques, in-situ IR for reaction monitoring, novel methodologies for kinetic analysis, and novel computational approaches). This volume focusses on mechanistic studies coupled with novel experimental and computational methods and brings together experts with a wide range of interests and backgrounds, including those developing new physical methods for mechanistic investigations and the potential end users of these methods. In this volume, the topics covered include: Physical methods for mechanistic understanding Understanding unusual element-element bond formation and activation Computational and theoretical approaches for mechanistic understanding Mechanistic insight into organic and industrial transformations
Download or read book Mechanistic Studies of Some Reactions of Square Planar Transition Metal Complexes in Solution written by John Reginald Lyons and published by . This book was released on 1968 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Organic Synthesis by Means of Transition Metal Complexes written by Jiro Tsuji and published by Springer. This book was released on 1975 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1970 I wrote a review article for "Topics in Current Chemistry", surveying the general reaction patterns of transition-metal complexes from the standpoint of organic synthesis. The article seems to have evoked wide interest, and I therefore thought it appropriate to treat the subject more comprehensively in the form of a monograph. Organometallic chemistry is a rapidly growing field of intensive research. In this field, the application of organometallic compounds to organic synthesis is an important subject and many unique synthetic methods have been discovered, especially in the last decade. Syntheses using transition-metal com pounds are now in the foreground of organic chemistry. The purpose of this monograph is to give a bird's-eye view of this field to both organic and inorganic chemists through a mechanistic approach. A systematic unification of the voluminous data accumulated in this field is now urgently required. This subject is discussed by classifying various reactions into general patterns and by illustrating them with a limited number of pertinent examples.
Download or read book Transition Metal Catalyzed Oxidative Cross Coupling Reactions written by Aiwen Lei and published by Springer. This book was released on 2019-02-04 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive text covering the research and development trends in the booming field of transition metal catalyzed oxidative cross-coupling reactions. Oxidative cross-coupling reaction is a new method to forming chemical bonds besides the traditional cross-coupling reactions. This book provides the answers to how this coupling reaction occurs and what its advantages are. The palladium, copper and iron catalyzed oxidative cross-coupling reactions as the main focuses of interest are described in detail. The oxidative cross-coupling reactions catalyzed by other metals and transition-metal-free oxidative coupling reactions are also introduced.This book provides a useful reference source for researchers and graduates in the field of transition metal catalyzed coupling reactions. It is also valuable to researchers working in pharmaceutical companies, fine organic chemical companies, and etc.
