Download or read book Muscle Plasticity Advances In Biochemical And Physiological Research written by José Magalhães and published by . This book was released on 2009-01-01 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological systems have acquired efficient adaptive strategies to cope with physiological challenges and to maximize biochemical processes under imposed constraints. All living organisms possess the inherent ability to change the structural and functional properties of their tissues in accordance to several health or disease-related conditions. Plasticity is the word used since the late 1970 s to designate all the processes and mechanisms behind adaptation. Muscle plasticity, in particular, is an unequivocal example of this biological feature. In fact, muscle is a very specialized tissue with an amazingly high malleability to adapt to distinct functional and metabolic demands by altering key molecular pathways. Moreover, as proposed in this book, muscle plasticity could also be extended to the ability of skeletal muscle to interact with other organs and mediate some of the stimuli-induced changes in other organs. Muscle cells are able to detect mechanical, metabolic, neuronal and hormonal signals which are transduced over multiple pathways to the muscle genome. Examples of muscle plasticity abound, from exercise adaptations, to the effects of environmental stressors, to the aging process, and to an assortment of disease-related conditions. Therefore, muscle plasticity forms a major basis for biological adaptation to physiological and pathophysiological conditions and thus, as we will become aware from the several chapters presented in this book, it can have both beneficial and maladaptive consequences. The goal of this multi-author book is to examine the current understanding regarding some physiological and biochemical events known to be involved in muscle adaptive response to altered health or disease-related circumstances. Notwithstanding the importance of other key organelles in cellular metabolism and function, muscle stimuli-targeting alterations in mitochondrial structure, biochemistry and function assume particular relevance throughout some chapters of this book. Issues related to muscle remodelling by physical exercise/contractile activity including molecular mechanisms of altered muscle use and hypertrophy, muscle disuse, aging processes, conditions of caloric restriction, hypoxia, as well as by some pathophysiological states such as obesity, cachexia, insulin resistance, diabetes mellitus, ischemia and ischemia-reperfusion make the scientific agenda of this book. As free radicals are known as powerful signalling molecules in cellular metabolism, a special emphasis on muscle redox-based modulation is noticeable throughout this book. However, even though this book covers a wide range of knowledge, it does not examine all aspects of physiology and biochemistry of muscle plasticity. Among many others, these would include several issues, such as inflammation, atrophy, satellite cell function in regeneration, regulation of excitation-contraction coupling, muscle architecture, as well as the response of muscle to distinct pharmacological agents. Topics like these are approached in other expertise devoted reviews. We are delighted to be involved in this project and gratefully acknowledged to the outstanding contribution of the authors. We hope that this book will be of interest to a wide basic and applied biomedical science audience, from physiologists to biochemists, especially those that embrace with excitement the wonders of muscle plasticity. Lastly, we also hope that the fascinating scientific platform of muscle plasticity would foster a plasticity of mind in developing new hypotheses and approaching challenges.

Download or read book Science and Development of Muscle Hypertrophy written by Brad J. Schoenfeld and published by Human Kinetics. This book was released on 2016-06-24 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Muscle hypertrophy—defined as an increase in muscular size—is one of the primary outcomes of resistance training. Science and Development of Muscle Hypertrophy is a comprehensive compilation of science-based principles to help professionals develop muscle hypertrophy in athletes and clients. With more than 825 references and applied guidelines throughout, no other resource offers a comparable quantity of content solely focused on muscle hypertrophy. Readers will find up-to-date content so they fully understand the science of muscle hypertrophy and its application to designing training programs. Written by Brad Schoenfeld, PhD, a leading authority on muscle hypertrophy, this text provides strength and conditioning professionals, personal trainers, sport scientists, researchers, and exercise science instructors with a definitive resource for information regarding muscle hypertrophy—the mechanism of its development, how the body structurally and hormonally changes when exposed to stress, ways to most effectively design training programs, and current nutrition guidelines for eliciting hypertrophic changes. The full-color book offers several features to make the content accessible to readers: • Research Findings sidebars highlight the aspects of muscle hypertrophy currently being examined to encourage readers to re-evaluate their knowledge and ensure their training practices are up to date. • Practical Applications sidebars outline how to apply the research conclusions for maximal hypertrophic development. • Comprehensive subject and author indexes optimize the book’s utility as a reference tool. • An image bank containing most of the art, photos, and tables from the text allows instructors and presenters to easily teach the material outlined in the book. Although muscle hypertrophy can be attained through a range of training programs, this text allows readers to understand and apply the specific responses and mechanisms that promote optimal muscle hypertrophy in their athletes and clients. It explores how genetic background, age, sex, and other factors have been shown to mediate the hypertrophic response to exercise, affecting both the rate and the total gain in lean muscle mass. Sample programs in the text show how to design a three- or four-day-per-week undulating periodized program and a modified linear periodized program for maximizing muscular development. Science and Development of Muscle Hypertrophy is an invaluable resource for strength and conditioning professionals seeking to maximize hypertrophic gains and those searching for the most comprehensive, authoritative, and current research in the field.

Download or read book Muscle Homeostasis and Regeneration written by Antonio Musarò and published by MDPI. This book was released on 2020-11-20 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases.

Download or read book Musculoskeletal Disorders and the Workplace written by Institute of Medicine and published by National Academies Press. This book was released on 2001-05-24 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every year workers' low-back, hand, and arm problems lead to time away from jobs and reduce the nation's economic productivity. The connection of these problems to workplace activities-from carrying boxes to lifting patients to pounding computer keyboards-is the subject of major disagreements among workers, employers, advocacy groups, and researchers. Musculoskeletal Disorders and the Workplace examines the scientific basis for connecting musculoskeletal disorders with the workplace, considering people, job tasks, and work environments. A multidisciplinary panel draws conclusions about the likelihood of causal links and the effectiveness of various intervention strategies. The panel also offers recommendations for what actions can be considered on the basis of current information and for closing information gaps. This book presents the latest information on the prevalence, incidence, and costs of musculoskeletal disorders and identifies factors that influence injury reporting. It reviews the broad scope of evidence: epidemiological studies of physical and psychosocial variables, basic biology, biomechanics, and physical and behavioral responses to stress. Given the magnitude of the problem-approximately 1 million people miss some work each year-and the current trends in workplace practices, this volume will be a must for advocates for workplace health, policy makers, employers, employees, medical professionals, engineers, lawyers, and labor officials.

Download or read book Sport and Exercise Nutrition written by Susan A. Lanham-New and published by John Wiley & Sons. This book was released on 2011-08-10 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Please note that digital editions do not include all the illustrations found in the printed book. Now widely adopted on courses throughout the world, the prestigious Nutrition Society Textbook series provides students with the scientific basics in nutrition in the context of a systems and disease approach rather than on a nutrient by nutrient basis. In addition books provide a means to enable teachers and students to explore the core principles of nutrition and to apply these throughout their training to foster critical thinking at all times. This NS Textbook on Sport and Exercise Nutrition has been written to cover the latest information on the science and practice of sport and exercise nutrition. A key concept behind this textbook is that it aims to combine the viewpoints of world leading nutrition experts from both academia/research and a practical stand point. Plus where necessary there are additional practitioner based authors to ensure theory is translated into practice for each chapter in the form of either ‘practice tips' or ‘information sheets' at the end of relevant chapters. The textbook in essence can be divided into three distinct but integrated parts: Part 1: covers the key components of the science that supports the practice of sport and exercise nutrition including comprehensive reviews on: nutrients both in general and as exercise fuels; exercise physiology; hydration, micronutrients; and supplements. Part 2: moves into focusing on specific nutrition strategies to support different types of training including: resistance; power/sprint; middle distance/speed endurance; endurance; technical/skill, team; and specific competition nutrition needs. The unique format of this textbook is that it breaks down nutrition support into training specific as opposed to the traditional sport specific support. This reflects the majority of current sport and exercise requirements of the need to undertake concurrent training and therefore facilitating targeted nutrition support to the different training components through the various macro and micro training cycles. Part 3: explores some of the practical issues encountered in working in the sport and exercise nutrition field and includes key sport related topics such as: disability sport; weight management; eating disorders; bone and gut health; immunity; injury; travel; and special populations and situations. READERSHIP: Students of nutrition and dietetics at both undergraduate and postgraduate level. All those working in the field of nutrition and related health sciences.

Download or read book The Structure and Function of Muscle Structure part I written by Geoffrey Howard Bourne and published by . This book was released on 1972 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biomechanics of Skeletal Muscles written by Vladimir M. Zatsiorsky and published by Human Kinetics. This book was released on 2012-04-10 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Richly illustrated and presented in clear, concise language, Biomechanics of Skeletal Muscles is an essential resource for those seeking advanced knowledge of muscle biomechanics. Written by leading experts Vladimir Zatsiorsky and Boris Prilutsky, the text is one of the few to look at muscle biomechanics in its entirety—from muscle fibers to muscle coordination—making it a unique contribution to the field. Using a blend of experimental evidence and mechanical models, Biomechanics of Skeletal Muscles provides an explanation of whole muscle biomechanics at work in the body in motion. The book first addresses the mechanical behavior of single muscles—from the sarcomere level up to the entire muscle. The architecture of human muscle, the mechanical properties of tendons and passive muscles, the biomechanics of active muscles, and the force transmission and shock absorption aspects of muscle are explored in detail. Next, the various issues of muscle functioning during human motion are addressed. The transformation from muscle force to joint movements, two-joint muscle function, eccentric muscle action, and muscle coordination are analyzed. This advanced text assumes some knowledge of algebra and calculus; however, the emphasis is on understanding physical concepts. Higher-level computational descriptions are placed in special sections in the later chapters of the book, allowing those with a strong mathematical background to explore this material in more detail. Readers who choose to skip over these sections will find that the book still provides a strong conceptual understanding of advanced topics. Biomechanics of Skeletal Muscles also contains numerous special features that facilitate readers’ comprehension of the topics presented. More than 300 illustrations and accompanying explanations provide an extensive visual representation of muscle biomechanics. Refresher sidebars offer brief reminders of mathematical and biomechanical concepts, and From the Literature sidebars present practical examples that illustrate the concepts under discussion. Chapter summaries and review questions provide an opportunity for reflection and self-testing, and reference lists at the end of each chapter provide a starting point for further study. Biomechanics of Skeletal Muscles offers a thorough explanation of whole muscle biomechanics, bridging the gap between foundational biomechanics texts and scientific literature. With the information found in this text, readers can prepare themselves to better understand the latest in cutting-edge research. Biomechanics of Skeletal Muscles is the third volume in the Biomechanics of Human Motion series. Advanced readers in human movement science gain a comprehensive understanding of the biomechanics of human motion as presented by one of the world’s foremost researchers on the subject, Dr. Vladimir Zatsiorsky. The series begins with Kinematics of Human Motion, which details human body positioning and movement in three dimensions; continues with Kinetics of Human Motion, which examines the forces that create body motion and their effects; and concludes with Biomechanics of Skeletal Muscles, which explains the action of the biological motors that exert force and produce mechanical work during human movement.

Download or read book The Resolution of Inflammation written by Adriano Rossi and published by Springer Science & Business Media. This book was released on 2008-03-17 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.

Download or read book Stretch Intensity and the Inflammatory Response A Paradigm Shift written by Nikos C. Apostolopoulos and published by Springer. This book was released on 2018-12-27 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this manuscript, practitioners and students who are concerned with sports and rehabilitation medicine, kinesiology, as well as coaches and athletes, are introduced to numerous concepts, including mechanotransduction, inflammation, pro- and anti-inflammatory cytokines, calpains, the extracellular matrix, neutrophils and macrophages, and their relevance to stretching, particularly stretching intensity. Although the quantitative parameters of training, duration, and frequency are important, it is the qualitative criterion of intensity (“how much”) that the author suggests is ultimately of greater concern. Intensity, the rate and magnitude of force, may be responsible for the proper recovery, regeneration, and adaptation of the musculoskeletal tissues from training, competition, or rehabilitation from injuries. Research suggests that too much force results in the stimulation of an inflammatory response, one associated with a biochemical feedback emerging from a mechanical stimulus. The intent of this manuscript is twofold: to initiate the discussion of the importance of stretching intensity with regard to proper recovery, regeneration, and adaptation, and to suggest that researchers need to explore its potential role in addressing numerous inflammatory (RA) and non-inflammatory (OA, recurrent tendinitis etc.) musculoskeletal conditions as well.

Download or read book The Physiology of Physical Training written by Zsolt Radák and published by Academic Press. This book was released on 2018-06-06 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Physiology of Physical Training provides complete coverage of the physiological and methodological aspects of physical training, providing essential knowledge for anyone involved in exercise physiology. Physiological processes at the cellular level (and for the whole organism) are covered to better explain particular training methods and convey a deeper knowledge and understanding of training techniques. Coverage of exercise training-induced adaptive responses and the most appropriate training methods to bring about targeted adaptive changes are also included. This is the perfect reference for researchers of physiology/kinesiology and human kinetics, practicing coaches, graduate students and sports medicine specialists. - Describes exercise-induced adaptation, from the cell to the whole body - Demonstrates practical applications of exercise for injury, disease prevention and improved physical performance - Fully integrates the knowledge of molecular exercise physiology and training methods

Download or read book Antioxidants in Sport Nutrition written by Manfred Lamprecht and published by CRC Press. This book was released on 2014-09-17 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.

Download or read book Fascia The Tensional Network of the Human Body written by Robert Schleip and published by Elsevier Health Sciences. This book was released on 2013-02-26 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the product of an important collaboration between clinicians of the manual therapies and scientists in several disciplines that grew out of the three recent International Fascia Research Congresses (Boston, Amsterdam, and Vancouver). The book editors, Thomas Findley MD PhD, Robert Schleip PhD, Peter Huijing PhD and Leon Chaitow DO, were major organizers of these congresses and used their extensive experience to select chapters and contributors for this book. This volume therefore brings together contributors from diverse backgrounds who share the desire to bridge the gap between theory and practice in our current knowledge of the fascia and goes beyond the 2007, 2009 and 2012 congresses to define the state-of-the-art, from both the clinical and scientific perspective. Prepared by over 100 specialists and researchers from throughout the world, Fascia: The Tensional Network of the Human Body will be ideal for all professionals who have an interest in fascia and human movement - physiotherapists, osteopathic physicians, osteopaths, chiropractors, structural integration practitioners, manual therapists, massage therapists, acupuncturists, yoga or Pilates instructors, exercise scientists and personal trainers - as well as physicians involved with musculoskeletal medicine, pain management and rehabilitation, and basic scientists working in the field. - Reflects the efforts of almost 100 scientists and clinicians from throughout the world - Offers comprehensive coverage ranging from anatomy and physiology, clinical conditions and associated therapies, to recently developed research techniques - Explores the role of fascia as a bodywide communication system - Presents the latest information available on myofascial force transmission which helps establish a scientific basis for given clinical experiences - Explores the importance of fascia as a sensory organ - for example, its important proprioceptive and nociceptive functions which have implications for the generation of low back pain - Describes new imaging methods which confirm the connectivity of organs and tissues - Designed to organize relevant information for professionals involved in the therapeutic manipulation of the body's connective tissue matrix (fascia) as well as for scientists involved in basic science research - Reflects the increasing need for information about the properties of fascia, particularly for osteopaths, massage therapists, physiotherapists and other complementary health care professionals - Offers new insights on the fascial related foundations of Traditional Chinese Medicine Meridians and the fascial effects of acupuncture

Download or read book Designing Resistance Training Programs written by Steven J. Fleck and published by Human Kinetics. This book was released on 2014-03-17 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designing Resistance Training Programs, Fourth Edition, is a guide to developing individualized training programs for both serious athletes and fitness enthusiasts. In this updated and expanded fourth edition, two of the world’s leading experts on strength training explore how to design scientifically based resistance training programs, modify and adapt programs to meet the needs of special populations, and apply the elements of program design in the real world. Fleck and Kraemer provide readers with a thorough understanding of the process of designing resistance training programs from both scientific and practical perspectives. As with previous editions, the fourth edition includes comprehensive tables that compare data and conclusions from research on core topics related to design of resistance training programs. By summarizing research and content for the reader, these tables offer a study guide, on-the-job reference, or starting point for further research. Designing Resistance Training Programs, Fourth Edition, is the only resource available that presents the body of research in the field in this organized and comprehensive format. The fourth edition has been thoroughly revised to present the most current information while retaining the studies that are the basis for concepts, guidelines, and applications in resistance training. Meticulously updated and heavily referenced, the fourth edition contains the following updates: • A full-color interior provides stronger visual appeal for the text. • Sidebars focus on a specific practical question or an applied research concept, allowing readers to connect research to real-life situations. • Multiple detailed tables summarize research from the text, offering an easy way to compare data and conclusions. • A glossary makes it simple to find key terms in one convenient location. • Newly added instructor ancillaries make the fourth edition a true learning resource for the classroom. Designing Resistance Training Programs, Fourth Edition, begins by outlining the principles of resistance training and exercise prescription, and examines the various types of strength training, including isometrics and eccentric training. This is followed by a discussion of resistance training from a physiological perspective and an overview of how resistance training programs interact with the other conditioning components such as aerobic, interval, plyometric, and flexibility training. Readers will then explore advanced training techniques, how to manipulate training variables in a long-term resistance training program, and ways to plan rest into long-term training that minimizes losses in fitness or performance gains. An important text for students, researchers, and practitioners, this textbook offers the information and tools to help readers evaluate resistance training programs and better understand the context and efficacy of new data findings in this ever-changing field. Designing Resistance Training Programs, Fourth Edition, is an essential resource for understanding the science behind resistance training and designing evidence-based resistance training programs for any population. This text provides the tools for understanding and designing resistance training programs for almost any situation or need.

Download or read book Exercise Metabolism written by Mark Hargreaves and published by Human Kinetics. This book was released on 2006 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive reference for biochemists, sport nutritionists, exercise physiologists, and graduate students in those disciplines. Provides information on the metabolic processes that take place during exercise, examining in depth the mobilization and utilization of substrates during physical activity. Focuses primarily on the skeletal muscle, but also discusses the roles of the liver and adipose tissue. Annotation copyright by Book News, Inc., Portland, OR

Download or read book The Unfolded Protein Response written by Roberto Pérez Torrado and published by . This book was released on 2022 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is divided in six section covering the most experimental approaches involved in the study of the unfolded protein response (UPR) pathway. Chapters detail determination of unfolded protein levels, methods to study UPR signal transmission, analysing the outcomes of the UPR pathway activation, UPR studies in mammalian models, UPR in alternative models, and UPR and disease. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, The Unfolded Protein Response: Methods and Protocols aims to describe key methods and approaches used in the study of the UPR pathway and its complex cellular implications. Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Download or read book Muscle Cell and Tissue written by Kunihiro Sakuma and published by BoD – Books on Demand. This book was released on 2018-10-10 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to complete tissue regeneration, various cells (neuronal, skeletal and smooth) interact coordinately with each other. This book, Muscle Cell and Tissue - Current Status of Research Field, deals with current progress and perspectives in a variety of topics on the skeletal and smooth muscle, stem cells, regeneration, disease or therapeutics. Novel applications for cell and tissue engineering including cell therapy, tissue models and disease pathology modeling are introduced. This book also deals with the differentiation/de-differentiation process of vascular smooth muscle cells in health and disease. Furthermore, natural products to reverse metabolic syndromes are descriptively reviewed. These chapters can be interesting for graduate students, teachers, physicians, executives and researchers in the field of molecular biology and regenerative medicine.

Download or read book Disorders of Voluntary Muscle written by George Karpati and published by Cambridge University Press. This book was released on 2001-07-12 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rewritten and redesigned, this remains the one essential text on the diseases of skeletal muscle.