Download or read book Designer Drugs written by Roy Gerona and published by Elsevier. This book was released on 2024-01-17 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: A title in the Emerging Issues in Analytical Chemistry series, Designer Drugs: Chemistry, Analysis, Regulation, Toxicology, Epidemiology & Legislation of New Psychoactive Substances presents both an overview and a guide to techniques for designer drug analysis. Proliferation of the synthesis and use of designer drugs is a serious public health problem with social, economic, and legal implications. Whether abuse is studied at the population level or the individual level, researchers need both background and highly detailed technical information on specific drugs and drug classes in order to combat the proliferation and highly damaging consequences of these substances. Author Roy Gerona provides a comprehensive discussion that emphasizes the potential threat to society, presents the ongoing challenges confronting the various laboratory approaches to detection and identification of new chemical entities, and informs the development of improved analytical solutions for use in legislation, law enforcement, and treatment. Designer Drugs: Chemistry, Analysis, Regulation, Toxicology, Epidemiology & Legislation of New Psychoactive Substances offers an introduction to the field and a source of information on specific drugs, drug effects, and analytical tools to a wide audience for anyone studying or engaging in designer drug analysis. Analytical and medical chemists, pharmacologist, toxicologists, and students, researchers, and policy makers in the fields of drug abuse, medicine, public health, and forensics will greatly benefit from this essential text. - Summarizes available literature and evaluates the strengths and weaknesses of analytical methods for detecting and identifying designer drugs - Directs the reader to sources of further reading at the conclusion of each chapter - Emphasizes the potential threat to society - Presents ongoing challenges confronting various laboratory approaches to detection and identification of new chemical entities

Download or read book Mass Spectra of Flavors and Fragrances of Natural and Synthetic Compounds written by Luigi Mondello and published by John Wiley & Sons. This book was released on 2015-03-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Component Identification in Complex Mixtures Essential oils are mixtures consisting of monoterpene andsesquiterpene hydrocarbons, their oxygenated derivatives, andaliphatic oxygenated compounds. The difficulties that arise in theGC-MS peak identification of these complex samples is due to thefact that many terpenes have identical mass spectra. This is aconsequence of similarities both in the initial molecule, or in thefragmentation patterns and rearrangements after ionization. Hence,MS identification of these compounds should always be accompaniedby retention time information that may support the MS librarysearch results. This innovative MS library for natural and synthetic products(essential oils, perfumes, etc.) makes the identification ofunknown compounds in complex mixtures easier, faster and morereliable. The use of chromatographic information, such as LinearRetention Index (LRI), can be used to filter MS results, enablingthe more reliable peak assignment of components in complexmixtures. Mass spectra, relative to standard and well-known simple matrixcomponents, were obtained and recorded through GC-MSseparation/identification. Furthermore, traditional informationrelative to each component (CAS number, common name, CAS name,molecular weight, compound formula, chemical class) plus linearretention index values are entered. Flavors and Fragrances of Natural and Synthetic Compounds,3rd edition contains >3000 mass spectra, LRI retentiondata, calculated Kovats RI, and searchable chemical structures ofcompounds of interest for the flavors and fragrances industry.Prepared by the Prof. Luigi Mondello under rigorous measurementconditions, the mass spectral library contains compounds central toflavor and fragrance research. What's on the disc: 1. FFNSC 3 in MS Search (Agilent, Bruker, Leco, JEOL, , Agilent .L(Chemstation, MassHunter), PerkinElmer Turbomass, Waters MassLynx,ACD ND9, and Cromatoplus 2. 30-Day trial version of Cromatoplus software

Download or read book Direct Analysis in Real Time Mass Spectrometry written by Yiyang Dong and published by John Wiley & Sons. This book was released on 2018-04-09 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clear, comprehensive, and state of the art, the groundbreaking book on the emerging technology of direct analysis in real time mass spectrometry Written by a noted expert in the field, Direct Analysis in Real Time Mass Spectrometry offers a review of the background and the most recent developments in DART-MS. Invented in 2005, DART-MS offers a wide range of applications for solving numerous analytical problems in various environments, including food science, forensics, and clinical analysis. The text presents an introduction to the history of the technology and includes information on the theoretical background, for exampleon the ionization mechanism. Chapters on sampling and coupling to different types of mass spectrometers are followed by a comprehensive discussion of a broad range of applications. Unlike most other ionization methods, DART does not require laborious sample preparation, as ionization takes place directly on the sample surface. This makes the technique especially attractive for applications in forensics and food science. Comprehensive in scope, this vital text: -Sets the standard on an important and emerging ionization technique -Thoroughly discusses all the relevant aspects from instrumentation to applications -Helps in solving numerous analytical problems in various applications, for example food science, forensics, environmental and clinical analysis -Covers mechanisms, coupling to mass spectrometers, and includes information on challenges and disadvantages of the technique Academics, analytical chemists, pharmaceutical chemists, clinical chemists, forensic scientists, and others will find this illuminating text a must-have resource for understanding the most recent developments in the field.

Download or read book Interpretation of MS MS Mass Spectra of Drugs and Pesticides written by Wilfried M. A. Niessen and published by John Wiley & Sons. This book was released on 2017-01-30 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of the interpretation of LC–MS–MS mass spectra of 1300 drugs and pesticides Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes This is the reference book for the interpretation of MS–MS mass spectra of small organic molecules Covers related therapeutic classes of compounds such as drugs for cardiovascular diseases, psychotropic compounds, drugs of abuse and designer drugs, antimicrobials, among many others Covers general fragmentation rule as well as specific fragmentation pathways for many chemical functional groups Gives an introduction to MS technology, mass spectral terminology, information contained in mass spectra, and to the identification strategies used for different types of unknowns

Download or read book Bioanalysis of Pharmaceuticals written by Steen Honoré Hansen and published by John Wiley & Sons. This book was released on 2015-07-20 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry is the first student textbook on the separation science and mass spectrometry of pharmaceuticals present in biological fluids with an educational presentation of the principles, concepts and applications. It discusses the chemical structures and properties of low- and high-molecular drug substances; the different types of biological samples and fluids that are used; how to prepare the samples by extraction, and how to perform the appropriate analytical measurements by chromatographic and mass spectrometric methods. Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry: Is an introductory student textbook discussing the different principles and concepts clearly and comprehensively, with many relevant and educational examples Focuses on substances that are administered as human drugs, including low-molecular drug substances, peptides, and proteins Presents both the basic principles that are regularly taught in universities, along with the practical use of bioanalysis as carried out by researchers in the pharmaceutical industry and in hospital laboratories Is aimed at undergraduate students, scientists, technicians and researchers in industry working in the areas of pharmaceutical analyses, biopharmaceutical analyses, biological and life sciences The book includes multiple examples to illustrate the theory and application, with many practical aspects including calculations, thus helping the student to learn how to convert the data recorded by instruments into the real concentration of the drug substances within the biological sample.

Download or read book Marine Cyanobacteria written by Loïc Charpy and published by Musee Oceanographique. This book was released on 1999 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Critical Issues in Alcohol and Drugs of Abuse Testing written by Amitava Dasgupta and published by Academic Press. This book was released on 2019-01-10 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more. - Serves as a ready resource of information for alcohol and drug testing - Ideal resource for making decisions related to the monitoring and interpretation of results - Includes concise content for clinical laboratory scientists, toxicologists and clinicians

Download or read book Technology in Forensic Science written by Deepak Rawtani and published by John Wiley & Sons. This book was released on 2020-11-02 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book "Technology in Forensic Science" provides an integrated approach by reviewing the usage of modern forensic tools as well as the methods for interpretation of the results. Starting with best practices on sample taking, the book then reviews analytical methods such as high-resolution microscopy and chromatography, biometric approaches, and advanced sensor technology as well as emerging technologies such as nanotechnology and taggant technology. It concludes with an outlook to emerging methods such as AI-based approaches to forensic investigations.

Download or read book Nanobiosensors written by Aiguo Wu and published by John Wiley & Sons. This book was released on 2020-06-02 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing cutting edge research on the hot topic of nanobiosensor, this book will become highly read Biosensor research has recently re-emerged as most vibrant area in recent years particularly after the advent of novel nanomaterials of multidimensional features and compositions. Nanomaterials of different types and striking properties have played a positive role in giving the boost and accelerated pace to biosensors development technology. Nanobiosensors - From Design to Applications covers several aspects of biosensors beginning from the basic concepts to advanced level research. It will help to bridge the gap between various aspects of biosensors development technology and applications. It covers biosensors related material in broad spectrum such as basic concepts, biosensors & their classification, biomarkers & their role in biosensors, nanostructures-based biosensors, applications of biosensors in human diseases, drug detection, toxins, and smart phone based biosensors. Nanobiosensors - From Design to Applications will prove a source of inspiration for research on biosensors, their local level development and consequently using for practical application in different industries such as food, biomedical diagnosis, pharmaceutics, agriculture, drug discovery, forensics, etc. * Discusses the latest technology and advances in the field of nanobiosensors and their applications in human diseases, drug detection, toxins * Offers a broad and comprehensive view of cutting-edge research on advanced materials such as carbon materials, nitride based nanomaterials, metal and metal oxide based nanomaterials for the fast-developing nanobiosensors research * Goes to a wide scientific and industry audience Nanobiosensors - From Design to Applications is a resource for polymer chemists, spectroscopists, materials scientists, physical chemists, surface chemists, and surface physicists.

Download or read book Synthetic Cathinones written by Jolanta B. Zawilska and published by Springer. This book was released on 2018-04-16 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, and particularly during the recent five years, a rapidly increasing number of novel psychoactive substance (NPSs), often marketed as “designer drugs”, “legal highs”, “herbal highs”, “research or intermediate chemicals” and “laboratory reagents”, has appeared on the drug market in an effort to bypass controlled substance legislation. NPSs encompass a wide range of different compounds and drug classes but had been dominated by synthetic cannabinomimetics and psychostimulatory synthetic cathinones, so-called β-keto amphetamines. Compounds from the later class were first detected in Europe in 2004, and since then 103 new cathinones have been identified and reported to the European Monitoring Centre for Drugs and Drug Addiction, with 57 during the last two years. Synthetic cathinones – novel addictive and stimulatory psychoactive substances is the first publication of this kind that provides readers with background on chemical structures, detection, prevalence and motivation of use of the very popular group of NPSs. This book also presents comprehensive overview of the mechanisms of action, pharmacological activity, and main metabolic pathways of synthetic cathinones, followed by a detailed discussion of the acute and chronic toxicity associated with the use of these substances. Written by international experts in the field, this multi-authored book is a valuable reference not only for scientists, clinicians and academics, but also for readers representing different professional background who are involved in educational-prophylactic activities directed to harm reduction of psychoactive compounds.

Download or read book Liquid Chromatography Mass Spectrometry MS MS and Time of Flight MS written by Imma Ferrer and published by American Chemical Society. This book was released on 2003-08-14 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores state-of-the-art mass spectrometric techniques. It focuses on liquid chromatography/mass spectrometry/mass spectrometry and time-of-flight/mass spectrometry to determine emerging contaminants, such as pharmaceuticals, hormones, pesticides, surfactants and unknown natural products.

Download or read book Current Analytical Trends in Drug Testing in Clinical and Forensic Toxicology written by Eugenia Gallardo and published by Frontiers Media SA. This book was released on 2021-06-24 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mass Spectrometry An Issue of Clinics in Laboratory Medicine written by Nigel Clarke and published by Elsevier Health Sciences. This book was released on 2011-12-28 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Clinics in Laboratory Medicine, Guest Edited by Nigel Clarke, MD, and Andrew Hoofnagle, MD, will focus on Mass Spectrometry, with topics including: Proteins; Peptides; Small Molecules: Toxicology; Small Molecules: Diagnostics; and Regulatory Considerations.

Download or read book Handbook of Forensic Medicine written by Burkhard Madea and published by John Wiley & Sons. This book was released on 2022-08-16 with total page 3306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Der Goldstandard unter den Referenzwerken der Rechtsmedizin In der zweiten Auflage des Handbook of Forensic Medicine vermittelt der Herausgeber Burkhard Madea der Leserschaft einen umfassenden, internationalen Ansatz in der Rechtsmedizin mithilfe eines Teams von Experten aus aller Welt. Das Buch enthält neue Inhalte zu den Themen Tatortuntersuchung, Analyse von Blutfleckenmustern, Terroranschläge, Brandkatastrophen, neue psychoaktive Substanzen und Molekularpathologie sowie einen umfassenden Überblick über sämtliche Aspekte der Rechtsmedizin. In den einzelnen Kapiteln werden alle Faktoren der Qualitätskontrolle und Best Practices behandelt. Anhand von Fallstudien werden die dort erläuterten Konzepte veranschaulicht und die Verbindungen zwischen verschiedenen Teildisziplinen hervorgehoben. Für Spezialisten, die täglich im Einsatz sind, werden in jedem Kapitel die Elemente der Routineanalyse behandelt. In der zweiten Auflage des Handbook of Forensic Medicine werden die neuesten Entwicklungen in der forensischen Molekularbiologie, der forensischen Toxikologie, der Molekularpathologie und der Immunhistochemie besprochen. Darüber hinaus bietet das Werk: * Eine gründliche Einführung in die Aufgaben der Rechtsmedizin in der modernen Gesellschaft mit einer Darstellung der internationalen Richtlinien und Akkreditierungen in der Rechtsmedizin * Umfassende Betrachtungen der medizinischen Aspekte des Todes, insbesondere des Wesens und der Definition von Tod, Autopsie und der Identifizierung der Opfer von Massenkatastrophen * Praktische Erörterungen zur Traumatologie und zum gewaltsamen Tod, insbesondere durch Ersticken, Stromschlag und Blitzschlag, Kindstötung und ärztliche Kunstfehler * Tiefgreifende Untersuchungen zum plötzlichen und unerwarteten Tod aus natürlichen Gründen, auch zur Biochemie nach dem Tod Dieses Buch ist unverzichtbar für jeden Experten in der Rechtsmedizin, Toxikologie und Hämogenetik sowie für alle, die Gutachten für Gerichtsverfahren erstellen sollen. Auch für Rechtsanwälte und Jurastudenten ist es ein ideales Nachschlagewerk.

Download or read book Forensic Science Handbook Volume I written by Adam B. Hall and published by CRC Press. This book was released on 2020-10-19 with total page 865 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in 1982 by Pearson/Prentice-Hall, the Forensic Science Handbook, Third Edition has been fully updated and revised to include the latest developments in scientific testing, analysis, and interpretation of forensic evidence. World-renowned forensic scientist, author, and educator Dr. Richard Saferstein once again brings together a contributor list that is a veritable Who’s Who of the top forensic scientists in the field. This Third Edition, he is joined by co-editor Dr. Adam Hall, a forensic scientist and Assistant Professor within the Biomedical Forensic Sciences Program at Boston University School of Medicine. This two-volume series focuses on the legal, evidentiary, biological, and chemical aspects of forensic science practice. The topics covered in this new edition of Volume I include a broad range of subjects including: • Legal aspects of forensic science • Analytical instrumentation to include: microspectrophotometry, infrared Spectroscopy, gas chromatography, liquid chromatography, capillary electrophoresis, and mass spectrometry • Trace evidence characterization of hairs, dust, paints and inks • Identification of body fluids and human DNA This is an update of a classic reference series and will serve as a must-have desk reference for forensic science practitioners. It will likewise be a welcome resource for professors teaching advanced forensic science techniques and methodologies at universities world-wide, particularly at the graduate level.

Download or read book WHO Expert Committee on Drug Dependence written by World Health Organization and published by World Health Organization. This book was released on 2023-03-08 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fundamentals of Analytical Toxicology written by Robert J. Flanagan and published by John Wiley & Sons. This book was released on 2020-08-03 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Analytical Toxicology is an integrated introduction to the analysis of drugs, poisons, and other foreign compounds in biological and related specimens. Assuming only basic knowledge of analytical chemistry, this invaluable guide helps trainee analytical toxicologists understand the principles and practical skills involved in detecting, identifying, and measuring a broad range of compounds in various biological samples. Clear, easy-to-read chapters provide detailed information on topics including sample collection and preparation, spectrophotometric and luminescence techniques, liquid and gas-liquid chromatography, and mass spectrometry including hyphenated techniques. This new edition contains thoroughly revised content that reflects contemporary practices and advances in analytical methods. Expanding the scope of the 1995 World Health Organization (WHO) basic analytical toxicology manual, the text includes coverage of separation science, essential pharmacokinetics, xenobiotic absorption, distribution and metabolism, clinical toxicological and substance misuse testing, therapeutic drug monitoring, trace elements and toxic metals analysis, and importantly the clinical interpretation of analytical results. Written by a prominent team of experienced practitioners, this volume: Focuses on analytical, statistical, and pharmacokinetic principles Describes basic methodology, including colour tests and immunoassay and enzyme-based assays Outlines laboratory operations, such as method validation, quality assessment, staff training, and laboratory accreditation Follows IUPAC nomenclature for chemical names and recommended International Non-proprietary Name (rINN) for drugs and pesticides Includes discussion of 'designer drugs' (novel pharmaceutical substances NPS) Fundamentals of Analytical Toxicology: Clinical and Forensic, 2nd Edition is an indispensable resource for advanced students and trainee analytical toxicologists across disciplines, such as clinical science, analytical chemistry, forensic science, pathology, applied biology, food safety, and pharmaceutical and pesticide development.