Download or read book Mapping the Future of Biology written by Anouk Barberousse and published by Springer Science & Business Media. This book was released on 2009-02-26 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carving Nature at its Joints? In order to map the future of biology we need to understand where we are and how we got there. Present day biology is the realization of the famous metaphor of the organism as a bete ˆ machine elaborated by Descartes in Part V of the Discours,a realization far beyond what anyone in the seventeenth century could have im- ined. Until the middle of the nineteenth century that machine was an articulated collection of macroscopic parts, a system of gears and levers moving gasses, solids, and liquids, and causing some parts of the machine to move in response to the force produced by others. Then, in the nineteenth century, two divergent changes occurred in the level at which the living machine came to be investigated. First, with the rise of chemistry and the particulate view of the composition of matter, the forces on macroscopic machine came to be understood as the ma- festation of molecular events, and functional biology became a study of molecular interactions. That is, the machine ceased to be a clock or a water pump and became an articulated network of chemical reactions. Until the ?rst third of the twentieth century this chemical view of life, as re?ected in the development of classical b- chemistry treated the chemistry of biological molecules in much the same way as for any organic chemical reaction, with reaction rates and side products that were the consequence of statistical properties of the concentrations of reactants.
Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Download or read book Shaping the Future written by National Research Council and published by National Academies Press. This book was released on 1989-02-01 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings the concerned individual up-to-date on the breakthroughs and social questions emerging from biology today. Author Steve Olson draws on the latest research in a number of fields as well as the views of leading biologists, ethicists, and philosophers. He tells the story of the intricate, often frustrating, path scientists must follow to find out why we are the way we are. The volume highlights groundbreaking research being done in four of biology's most exciting fields: genetics, development, neurobiology, and evolution. In each field, the implications of this research extend far beyond basic biology, ranging from human gene therapy to cancer, from neural transplantation to the evolution of the atmosphere.
Download or read book Invasion Biology written by Jonathan M Jeschke and published by CABI. This book was released on 2018-04-25 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are many hypotheses describing the interactions involved in biological invasions, but it is largely unknown whether they are backed up by empirical evidence. This book fills that gap by developing a tool for assessing research hypotheses and applying it to twelve invasion hypotheses, using the hierarchy-of-hypotheses (HoH) approach, and mapping the connections between theory and evidence. In Part 1, an overview chapter of invasion biology is followed by an introduction to the HoH approach and short chapters by science theorists and philosophers who comment on the approach. Part 2 outlines the invasion hypotheses and their interrelationships. These include biotic resistance and island susceptibility hypotheses, disturbance hypothesis, invasional meltdown hypothesis, enemy release hypothesis, evolution of increased competitive ability and shifting defence hypotheses, tens rule, phenotypic plasticity hypothesis, Darwin's naturalization and limiting similarity hypotheses and the propagule pressure hypothesis. Part 3 provides a synthesis and suggests future directions for invasion research.
Download or read book Introduction to Computational Biology written by Michael S. Waterman and published by CRC Press. This book was released on 2018-05-02 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology is in the midst of a era yielding many significant discoveries and promising many more. Unique to this era is the exponential growth in the size of information-packed databases. Inspired by a pressing need to analyze that data, Introduction to Computational Biology explores a new area of expertise that emerged from this fertile field- the combination of biological and information sciences. This introduction describes the mathematical structure of biological data, especially from sequences and chromosomes. After a brief survey of molecular biology, it studies restriction maps of DNA, rough landmark maps of the underlying sequences, and clones and clone maps. It examines problems associated with reading DNA sequences and comparing sequences to finding common patterns. The author then considers that statistics of pattern counts in sequences, RNA secondary structure, and the inference of evolutionary history of related sequences. Introduction to Computational Biology exposes the reader to the fascinating structure of biological data and explains how to treat related combinatorial and statistical problems. Written to describe mathematical formulation and development, this book helps set the stage for even more, truly interdisciplinary work in biology.
Download or read book Systematics and the Origin of Species written by National Academy of Sciences and published by National Academies Press. This book was released on 2005-09-28 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: In December 2004, the National Academy of Sciences sponsored a colloquium on "Systematics and the Origin of Species" to celebrate Ernst Mayr's 100th anniversary and to explore current knowledge concerning the origin of species. In 1942, Ernst Mayr, one of the twentieth century's greatest scientists, published Systematics and the Origin of Species, a seminal book of the modern theory of evolution, where he advanced the significance of population variation in the understanding of evolutionary process and the origin of new species. Mayr formulated the transition from Linnaeus's static species concept to the dynamic species concept of the modern theory of evolution and emphasized the species as a community of populations, the role of reproductive isolation, and the ecological interactions between species. In addition to a preceding essay by Edward O. Wilson, this book includes the 16 papers presented by distinguished evolutionists at the colloquium. The papers are organized into sections covering the origins of species barriers, the processes of species divergence, the nature of species, the meaning of "species," and genomic approaches for understanding diversity and speciation.
Download or read book It s Alive written by Chris Meyer and published by Currency. This book was released on 2003-05-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why we are on the cusp of a new economic era that will make the changes and challenges of the Information Era seem like child’s play From the bestselling authors of Blur—a defining book of the Information Age—comes a startling glimpse into the near future and the emerging economy that awaits us. It’s Alive foretells the jolt the world is about to receive as the science of molecular evolution races out of the laboratories and into the business world. Think back to the early 1970s. Imagine the opportunities for your business, career choice, and investments had you received an advance report on the ways in which computer and information technology would revolutionize the world. It’s Alive provides that opportunity today: a realistic and persuasive look into the future—the molecular economy—and how it is starting to overtake and reshape the Information Age. Today’s gene mapping and molecular engineering are equivalent to the introduction of transistor radios at the advent of the information economy. Solid-state technology moved from the labs into the business arena, providing in turn the transistor, the microprocessor, and the modem—and the information business. During the next ten years, molecular technology will follow the same pattern, moving from the lab and into the basic operation of the corporation itself. Chris Meyer and Stan Davis are our guides in understanding this new future. They show that not only biological systems evolve. The rules of evolution help explain the process of change in biology, business, and the economy, thereby providing a management guide to the business world around the corner. It’s Alive is not science fiction or futurism. It bases its insights and predictions on the impact the molecular economy is already having in such diverse business environments as manufacturing, financial services, and energy. Through in-depth case studies of Capital One Financial, the U.S. Marine Corps, British Petroleum, and the biotech firm Maxygen, Meyer and Davis show how adaptive behavior works in the real world. As the rules of evolution combine with the connected economy, our business world will become unpredictable, volatile, and continually adaptive—in other words, alive. Also available as an eBook.
Download or read book Mapping Humanity written by Joshua Z. Rappoport and published by BenBella Books. This book was released on 2020-07-07 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A good companion for those with a science background interested in learning more about human genetics." —Booklist Thanks to the popularity of personal genetic testing services, it's now easier than ever to get information about our own unique DNA—but who does this information really benefit? And, as genome editing and gene therapy transform the healthcare landscape, what do we gain—and what might we give up in return? Inside each of your cells is the nucleus, a small structure that contains all of the genetic information encoded by the DNA inside, your genome. Not long ago, the first human genome was sequenced at a cost of nearly $3 billion; now, this same test can be done for about $1,000. This new accessibility of genome sequence information creates huge potential for advances in how we understand and treat disease, among other things. It also raises significant concerns regarding ethics and personal privacy. In Mapping Humanity: How Modern Genetics Is Changing Criminal Justice, Personalized Medicine, and Our Identities, cellular biology expert Joshua Z. Rappoport provides a detailed look at how the explosion in genetic information as a result of cutting-edge technologies is changing our lives and our world. Inside, discover: • An in-depth look at how your personal genome creates the unique individual that you are • How doctors are using DNA sequencing to identify the underlying genetic causes of disease • Why the field of gene therapy offers amazing potential for medical breakthroughs—and why it's taking so long • The fantastic potential—and troubling concerns—surrounding genome editing • The real impact—and validity—of popular personal genetic testing products, such as 23andMe • Details of how molecular biology and DNA are changing the criminal justice system • Facts you should know about Genetically Modified Organisms (GMOs) Throughout, in compelling, accessible prose, Rappoport explores the societal, ethical, and economic impacts of this new era. Offering a framework for balancing the potential risks and benefits of genetic information technologies and genetic engineering, Mapping Humanity is an indispensable guide to navigating the possibilities and perils of our gene-centric future.
Download or read book What Remains to Be Discovered written by John Maddox and published by Free Press. This book was released on 1999-11-05 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: What wonders of science will the 21st century bring? John Maddox takes up this challenge by describing precisely what remains to be discovered. Building on twenty-three years' experience at the helm of the world's preeminent science magazine, Nature, Maddox identifies new areas of discovery in physics, biology, health, intelligence, and global catastrophe. As Maddox shows, the rate of scientific discovery will continue to accelerate, hurtling us toward ever more exciting discoveries in the next century.
Download or read book The Next 500 Years written by Christopher E. Mason and published by MIT Press. This book was released on 2022-04-12 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: An argument that we have a moral duty to explore other planets and solar systems--because human life on Earth has an expiration date. Inevitably, life on Earth will come to an end, whether by climate disaster, cataclysmic war, or the death of the sun in a few billion years. To avoid extinction, we will have to find a new home planet, perhaps even a new solar system, to inhabit. In this provocative and fascinating book, Christopher Mason argues that we have a moral duty to do just that. As the only species aware that life on Earth has an expiration date, we have a responsibility to act as the shepherd of life-forms--not only for our species but for all species on which we depend and for those still to come (by accidental or designed evolution). Mason argues that the same capacity for ingenuity that has enabled us to build rockets and land on other planets can be applied to redesigning biology so that we can sustainably inhabit those planets. And he lays out a 500-year plan for undertaking the massively ambitious project of reengineering human genetics for life on other worlds. As they are today, our frail human bodies could never survive travel to another habitable planet. Mason describes the toll that long-term space travel took on astronaut Scott Kelly, who returned from a year on the International Space Station with changes to his blood, bones, and genes. Mason proposes a ten-phase, 500-year program that would engineer the genome so that humans can tolerate the extreme environments of outer space--with the ultimate goal of achieving human settlement of new solar systems. He lays out a roadmap of which solar systems to visit first, and merges biotechnology, philosophy, and genetics to offer an unparalleled vision of the universe to come.
Download or read book A New Biology for the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2009-11-20 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now more than ever, biology has the potential to contribute practical solutions to many of the major challenges confronting the United States and the world. A New Biology for the 21st Century recommends that a "New Biology" approach-one that depends on greater integration within biology, and closer collaboration with physical, computational, and earth scientists, mathematicians and engineers-be used to find solutions to four key societal needs: sustainable food production, ecosystem restoration, optimized biofuel production, and improvement in human health. The approach calls for a coordinated effort to leverage resources across the federal, private, and academic sectors to help meet challenges and improve the return on life science research in general.
Download or read book Translational Systems Biology written by Yoram Vodovotz and published by Elsevier. This book was released on 2014-10-08 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are we satisfied with the rate of drug development? Are we happy with the drugs that come to market? Are we getting our money's worth in spending for basic biomedical research? In Translational Systems Biology, Drs. Yoram Vodovotz and Gary An address these questions by providing a foundational description the barriers facing biomedical research today and the immediate future, and how these barriers could be overcome through the adoption of a robust and scalable approach that will form the underpinning of biomedical research for the future. By using a combination of essays providing the intellectual basis of the Translational Dilemma and reports of examples in the study of inflammation, the content of Translational Systems Biology will remain relevant as technology and knowledge advances bring broad translational applicability to other diseases. Translational systems biology is an integrated, multi-scale, evidence-based approach that combines laboratory, clinical and computational methods with an explicit goal of developing effective means of control of biological processes for improving human health and rapid clinical application. This comprehensive approach to date has been utilized for in silico studies of sepsis, trauma, hemorrhage, and traumatic brain injury, acute liver failure, wound healing, and inflammation. - Provides an explicit, reasoned, and systematic approach to dealing with the challenges of translational science across disciplines - Establishes the case for including computational modeling at all stages of biomedical research and healthcare delivery, from early pre-clinical studies to long-term care, by clearly delineating efficiency and costs saving important to business investment - Guides readers on how to communicate across domains and disciplines, particularly between biologists and computational researchers, to effectively develop multi- and trans-disciplinary research teams
Download or read book The Science of Roman History written by Walter Scheidel and published by Princeton University Press. This book was released on 2019-10-15 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: With state-of-the-art contributions by scholars who are leaders in their respective fields, this edition describes how the integration of natural and human archives is changing the entire historical enterprise.
Download or read book The Maize Genome written by Jeffrey Bennetzen and published by Springer. This book was released on 2018-11-24 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses advances in our understanding of the structure and function of the maize genome since publication of the original B73 reference genome in 2009, and the progress in translating this knowledge into basic biology and trait improvement. Maize is an extremely important crop, providing a large proportion of the world’s human caloric intake and animal feed, and serving as a model species for basic and applied research. The exceptionally high level of genetic diversity within maize presents opportunities and challenges in all aspects of maize genetics, from sequencing and genotyping to linking genotypes to phenotypes. Topics covered in this timely book range from (i) genome sequencing and genotyping techniques, (ii) genome features such as centromeres and epigenetic regulation, (iii) tools and resources available for trait genomics, to (iv) applications of allele mining and genomics-assisted breeding. This book is a valuable resource for researchers and students interested in maize genetics and genomics.
Download or read book A Machine to Make a Future written by Paul Rabinow and published by Princeton University Press. This book was released on 2013-10-31 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Machine to Make a Future represents a remarkably original look at the present and possible future of biotechnology research in the wake of the mapping of the human genome. The central tenet of Celera Diagnostics--the California biotech company whose formative work during 2003 is the focus of the book--is that the emergent knowledge about the genome, with its profound implications for human health, can now be turned into a powerful diagnostic apparatus--one that will yield breakthrough diagnostic and therapeutic products (and, potentially, profit). Celera's efforts--assuming they succeed--may fundamentally reshape the fabric of how health and health care are understood, practiced, and managed. Presenting a series of interviews with all of the key players in Celera Diagnostics, Paul Rabinow and Talia Dan-Cohen open a fascinating window on the complexity of corporate scientific innovation. This marks a radical departure from other books on the biotech industry by chronicling the vicissitudes of a project during a finite time period, in the words of the actors themselves. Ultimately, the authors conclude, Celera Diagnostics is engaged in a future characterized not by geniuses and their celebrated discoveries but by a largely anonymous and widely distributed profusion of data and results--a "machine to make a future." In their new afterword, Rabinow and Dan-Cohen revisit Celera Diagnostics as its mighty machine grinds along, wondering, along with the scientists, "what constitutes success and what constitutes failure?" The pathos of the situation turns on how one poses the question as much as how one answers it.
Download or read book Future Evolution written by Peter D. Ward and published by W. H. Freeman. This book was released on 2002-01-06 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everyone wonders what tomorrow holds, but what will the real future look like? Not decades or even hundreds of years from now, but thousands or millions of years into the future. Will our species change radically? Or will we become builders of the next dominant intelligence on Earth- the machine? These and other seemingly fantastic scenarios are the very possible realities explored in Peter Ward's Future Evolution, a penetrating look at what might come next in the history of the planet. Looking to the past for clues about the future, Ward describes how the main catalyst for evolutionary change has historically been mass extinction. While many scientist direly predict that humanity will eventually create such a situation, Ward argues that one is already well underway--the extinction of large mammals--and that a new Age of Humanity is coming that will radically revise the diversity of life on Earth. Finally, Ward examines the question of human extinction and reaches the startling conclusion that the likeliest scenario is not our imminent demise but long term survival--perhaps reaching as far as the death of the Sun! Full of Alexis Rockman's breathtaking color images of what animals, plants and other organisms might look like thousands and millions of years from now, Future Evolution takes readers on an incredible journey through time from the deep past into the far future.
Download or read book Climate Change Biology written by Lee Hannah and published by Academic Press. This book was released on 2017-02-17 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Climate Change Biology is a new textbook which examines this emerging discipline of human-induced climate change and the resulting shifts in the distributions of species and the timing of biological events. The text focuses on understanding the impacts of human-induced climate change, but draws on multiple lines of evidence, including paleoecology, modelling and current observation. Climate Change Biology lays out the scope and depth of understanding of this new discipline in terms that are accessible to students, managers and professional biologists. The only advanced student text on the biological aspects of climate change Examines recent and deep past climate change effects to better understand the impacts of recent human-induced changes Discusses the conservation and other ecological implications of climate change in detail Presents recipes for coping with accelerating climate change in the future Includes extensive illustrations with maps diagrams and color photographs
