Download or read book Managing Discovery in the Life Sciences written by Philip A. Rea and published by Cambridge University Press. This book was released on 2018-02-01 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, distinguished scholars Philip A. Rea, Mark V. Pauly, and Lawton R. Burns explore the science and management behind marketable biomedical innovations. They look at how the science actually played out through the interplay of personalities, the cultures within and between academic and corporate entities, and the significance of serendipity not as a mysterious phenomenon but one intrinsic to the successes and failures of the experimental approach. With newly aggregated data and case studies, they consider the fundamental economic underpinnings of investor-driven discovery management, not as an obstacle or deficiency as its critics would contend or as something beyond reproach as some of its proponents might claim, but as the only means by which scientists and managers can navigate the unknowable to discover new products and decide how to sell them so as to maximize the likelihood of establishing a sustainable pipeline for still more marketable biomedical innovations.
Download or read book Managing Discovery in the Life Sciences written by Philip A. Rea and published by Cambridge University Press. This book was released on 2018-02-01 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, distinguished scholars Philip A. Rea, Mark V. Pauly, and Lawton R. Burns explore the science and management behind marketable biomedical innovations. They look at how the science actually played out through the interplay of personalities, the cultures within and between academic and corporate entities, and the significance of serendipity not as a mysterious phenomenon but one intrinsic to the successes and failures of the experimental approach. With newly aggregated data and case studies, they consider the fundamental economic underpinnings of investor-driven discovery management, not as an obstacle or deficiency as its critics would contend or as something beyond reproach as some of its proponents might claim, but as the only means by which scientists and managers can navigate the unknowable to discover new products and decide how to sell them so as to maximize the likelihood of establishing a sustainable pipeline for still more marketable biomedical innovations.
Download or read book Innovative Research in Life Sciences written by E. Andrew Balas and published by John Wiley & Sons. This book was released on 2018-11-08 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: “I thoroughly enjoyed reading this book as it has taken me on a journey through time, across the globe and through multiple disciplines. Indeed, we need to be thinking about these concepts and applying them every day to do our jobs better.” Farah Magrabi, Macquarie University, Australia “The reader will find intriguing not only the title but also the content of the book. I’m also pleased that public health, and even more specifically epidemiology has an important place in this ambitious discussion.” Elena Andresen, Oregon Health & Science University, USA “This book is very well written and addresses an important topic. It presents many reasons why basic scientists/researchers should establish collaborations and access information outside traditional means and not limit thinking but rather expand such and perhaps develop more innovative and translational research ventures that will advance science and not move it laterally.” Gerald Pepe, Eastern Virginia Medical School, USA “This book gathers logically and presents interestingly (with many examples) the qualities and attitudes a researcher must possess in order to become successful. On the long run, the deep and carefully reexamined research will be the one that lasts.” Zoltán Néda, Babeş-Bolyai University, Romania “I really liked the five pillars delineating the components of humanism in research. This book has made a major contribution to the research ethics literature.” David Fleming, University of Missouri, USA A comprehensive review of the research phase of life sciences from design to discovery with suggestions to improve innovation This vital resource explores the creative processes leading to biomedical innovation, identifies the obstacles and best practices of innovative laboratories, and supports the production of effective science. Innovative Research in Life Sciences draws on lessons from 400 award-winning scientists and research from leading universities. The book explores the innovative process in life sciences and puts the focus on how great ideas are born and become landmark scientific discoveries. The text provides a unique resource for developing professional competencies and applied skills of life sciences researchers. The book examines what happens before the scientific paper is submitted for publication or the innovation becomes legally protected. This phase is the most neglected but most exciting in the process of scientific creativity and innovation. The author identifies twelve competencies of innovative biomedical researchers that described and analyzed. This important resource: Highlights the research phase from design to discovery that precedes innovation disclosure Offers a step by step explanation of how to improve innovation Offers solutions for improving research and innovation productivity in the life sciences Contains a variety of statistical databases and a vast number of stories about individual discoveries Includes a process of published studies and national statistics of biomedical research and reviews the performance of research labs and academic institutions Written for academics and researchers in biomedicine, pharmaceutical science, life sciences, drug discovery, pharmacology, Innovative Research in Life Sciences offers a guide to the creative processes leading to biomedical innovation and identifies the best practices of innovative scientists and laboratories.
Download or read book Managing the Drug Discovery Process written by Susan Miller and published by Elsevier. This book was released on 2023-03-09 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. - Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena - Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work - Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable - Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters
Download or read book Managing the Drug Discovery Process written by Susan Miller and published by Woodhead Publishing. This book was released on 2016-11-08 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing the Drug Discovery Process: How to Make It More Efficient and Cost-Effective thoroughly examines the current state of pharmaceutical research and development by providing chemistry-based perspectives on biomedical research, drug hunting and innovation. The book also considers the interplay of stakeholders, consumers, and the drug firm with attendant factors, including those that are technical, legal, economic, demographic, political, social, ecological, and infrastructural. Since drug research can be a high-risk, high-payoff industry, it is important to researchers to effectively and strategically manage the drug discovery process. This book takes a closer look at increasing pre-approval costs for new drugs and examines not only why these increases occur, but also how they can be overcome to ensure a robust pharmacoeconomic future. Written in an engaging manner and including memorable insights, this book is aimed at redirecting the drug discovery process to make it more efficient and cost-effective in order to achieve the goal of saving countless more lives through science. A valuable and compelling resource, this is a must-read for all students and researchers in academia and the pharmaceutical industry. - Considers drug discovery in multiple R&D venues, including big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work - Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable
Download or read book Life Sciences Industry written by Basanta Kumara Bahera and published by Springer Nature. This book was released on 2021-08-24 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic principles of applied life sciences such as recombinant DNA technology is used in most life sciences industries marketing bio-formulations for designing more effective protein-based drugs, such as erythropoietin and fast-acting insulin etc. In recent times genetically engineered host cells from mammal, animal and plants are also being used in life sciences industries to manufacture biologics. This book discusses the most basic as well advanced issues on biological products for successfully managing a life sciences industry. It elucidates the life cycle of biological molecules, right from the conceptual development of different types of biopolymers, and their subsequent transfer from the conical flasks in laboratory to life sciences industries for large scale production and marketing. It focuses on sustainable longevity in the life cycle of commercial biopolymers. Cumulative facts and figures in this volume would immensely help in inspiring life sciences industry promoters to monitor value chain transfer process of biologics for better profitability. Additionally, it would serve as a perusal document for the students and researchers interested in entrepreneurial ventures or having their own start-up projects for the commercialization of biologics.
Download or read book Drug Discovery Unit written by University of Dundee. College of Life Sciences and published by . This book was released on 2014 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Driving Science Information Discovery in the Digital Age written by Svetla Baykoucheva and published by Chandos Publishing. This book was released on 2021-09-30 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: New digital technologies have transformed how scientific information is created, disseminated—and discovered. The emergence of new forms of scientific publishing based on open science and open access have caused a major shift in scientific communication and a restructuring of the flow of information. Specialized indexing services and search engines are trying to get into information seekers' minds to understand what users are actually looking for when typing all these keywords or drawing chemical structures. Using artificial intelligence (AI), machine learning, and semantic indexing, these "discovery agents" are trying to anticipate users' information needs. In this highly competitive environment, authors should not sit and rely only on publishers, search engines, and indexing services to make their works visible. They need to communicate about their research and reach out to a larger audience. Driving Science Information Discovery in the Digital Age looks through the "eyes" of the main "players" in this "game" and examines the discovery of scientific information from three different, but intertwined, perspectives: - Discovering, managing, and using information (Information seeker perspective) - Publishing, disseminating, and making information discoverable (Publisher perspective) - Creating, spreading, and promoting information (Author perspective). - Presents an overview of the current scientific publishing landscape - Shows how users can search for scientific information more efficiently - Critically analyses the metrics used to measure the quality of journals and the impact of research - Looks at the discovery of scientific information from the perspectives of information seekers, publishers, and authors - Delves into the practices used by specialized indexing services and search engines to process scientific information and make it discoverable - Recommends strategies that authors could use to promote their research
Download or read book Life Sciences Client Strategies written by Aspatore Books and published by . This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life Sciences Client Strategies is an authoritative, insiders perspective on key strategies for working with clients in the life sciences legal arena. Featuring partners and shareholders from some of the nations leading law firms, these experts guide the reader through best practices for dealing with some of the major issues of concern for life sciences companies, with a focus on managing intellectual property. These top lawyers give tips on meeting with new clients, obtaining key documentation, and developing a positive attorney-client relationship. From procuring and licensing patents to patent prosecution, these authors reveal how to add the most value for your client in terms of achieving business goals and avoiding common mistakes related to intellectual property protection. Additionally, these leaders discuss strategies for obtaining funding, managing strategic alliances, and addressing regulatory issues.
Download or read book The New Players in Life Science Innovation written by Tomasz F. Mroczkowski and published by Ft Press. This book was released on 2012 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global center of gravity in life sciences innovation is rapidly shifting to emerging economies. In The New Players in Life Science Innovation, Tomasz Mroczkowski explains how China and other new economic powers are rapidly gaining leadership positions, and thoroughly assesses the implications. Mroczkowski discusses the sophisticated innovation strategies and reforms these nations have implemented: approaches that don't rely on market forces alone, and are achieving remarkable success. Next, he previews the emerging global "bio-economy," in which life science discoveries will be applied pervasively in markets ranging from health to fuels. As R&D in the West becomes increasingly costly, Mroczkowski introduces new options for partnering with new players in the field. He thoroughly covers the globalization of clinical trials, showing how it offers opportunities that go far beyond cost reduction, and assessing the unique challenges it presents. Offering examples from China to Dubai to India, he carefully assesses the business models driving today's newest centers of innovation. Readers will find up-to-date coverage of bioparks, technology zones, and emerging clusters, and realistic assessments of global R&D collaboration strategies such as those of Eli Lilly, Merck, Novartis, and IBM. With innovation-driven industries increasingly dominating the global economy, this book's insights are indispensable for every R&D decision-maker and investor.
Download or read book Open Source Software in Life Science Research written by Lee Harland and published by Elsevier. This book was released on 2012-10-31 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems.The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an 'omics' platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry. - Discusses a broad range of applications from a variety of sectors - Provides a unique perspective on work normally performed behind closed doors - Highlights the criteria used to compare and assess different approaches to solving problems
Download or read book Life Sciences 2018 written by IAM (Intellectual Asset Management) and published by . This book was released on 2018 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biological Knowledge Discovery Handbook written by Mourad Elloumi and published by Wiley. This book was released on 2013-12-13 with total page 1192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive overview of preprocessing, mining, and postprocessing of biological data Molecular biology is undergoing exponential growth in both the volume and complexity of biological data-and knowledge discovery offers the capacity to automate complex search and data analysis tasks. This book presents a vast overview of the most recent developments on techniques and approaches in the field of biological knowledge discovery and data mining (KDD)-providing in-depth fundamental and technical field information on the most important topics encountered.
Download or read book Chemical Information Mining written by Debra L. Banville and published by CRC Press. This book was released on 2008-12-15 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: The First Book to Describe the Technical and Practical Elements of Chemical Text Mining Explores the development of chemical structure extraction capabilities and how to incorporate these technologies in daily research work For scientific researchers, finding too much information on a subject, not finding enough information, or not being able to access full text documents often costs them time, money, and quality. Addressing these concerns, Chemical Information Mining: Facilitating Literature-Based Discovery presents strategic ideas for properly selecting and successfully using the best text mining tools for scientific research. Links chemical and biological entities at the heart of life science research The book focuses on information extraction issues, highlights available solutions, and underscores the value of these solutions to academic and commercial scientists. After introducing the drivers behind chemical text mining, it discusses chemical semantics. The contributors describe the tools that identify and convert chemical names and images to structure-searchable information. They also explain natural language processing, name entity recognition concepts, and semantic web technologies. Following a section on current trends in the field, the book looks at where information mining approaches fit into the research needs within the life sciences. Shaping the future of scientific information and knowledge management By building knowledge and competency in the growing area of literature-based discovery, this book shows how text mining of the chemical literature can increase drug discovery opportunities and enhance life science research.
Download or read book Computational Life Sciences written by Jens Dörpinghaus and published by Springer. This book was released on 2024-03-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book broadly covers the given spectrum of disciplines in Computational Life Sciences, transforming it into a strong helping hand for teachers, students, practitioners and researchers. In Life Sciences, problem-solving and data analysis often depend on biological expertise combined with technical skills in order to generate, manage and efficiently analyse big data. These technical skills can easily be enhanced by good theoretical foundations, developed from well-chosen practical examples and inspiring new strategies. This is the innovative approach of Computational Life Sciences-Data Engineering and Data Mining for Life Sciences: We present basic concepts, advanced topics and emerging technologies, introduce algorithm design and programming principles, address data mining and knowledge discovery as well as applications arising from real projects. Chapters are largely independent and often flanked by illustrative examples and practical advise.
Download or read book Knowledge Discovery Knowledge Engineering and Knowledge Management written by Ana Fred and published by Springer. This book was released on 2013-01-05 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed post-conference proceedings of the Second International Joint Conference on Knowledge Discovery, Knowledge Engineering, and Knowledge Management, IC3K 2010, held in Valencia, Spain, in October 2010. This book includes revised and extended versions of a strict selection of the best papers presented at the conference; 26 revised full papers together with 2 invited lectures were carefully reviewed and selected from 369 submissions. According to the three covered conferences KDIR 2010, KEOD 2010, and KMIS 2010, the papers are organized in topical sections on knowledge discovery and information retrieval, knowledge engineering and ontology development, and on knowledge management and information sharing.
Download or read book Life Science Management written by Avo Schönbohm and published by Springer Nature. This book was released on 2022-07-14 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The COVID-19 pandemic has reminded us of how important the life science industry is, and compels us to find efficient management methods specific to the industry. Pharmaceuticals, drug and vaccine development labs, R&D labs, medical instrumentation, and tech companies, hygiene supply companies, medical distribution chains, all form an integral part of this industry. At the interface of scientific research, technology, innovation and management and embedded in regulatory and legal frameworks, life science management is still an under-researched field of practice and science. This edited volume addresses this research gap and offers a wide range of practical and theoretical contributions that provide insights into one of the most exciting industries. The book is primarily directed at practitioners and decision makers in the life science industry. Students and professionals of life science management at all levels as well as policy makers will find valuable insights and inspiration for their daily work and career development.
