Download or read book Mammary Tumor Cell Cycle Differentiation and Metastasis written by Robert B. Dickson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammary Tumor Cell Cycle, Differentiation and Metastasis is the fifth volume since 1988 in a series designed to broadly examine current advances in the cellular and molecular biology of breast cancer. As in previous volumes, the editors have invited recognized experts in cutting-edge topics to provide a chapter focused on their area of research. The editors have turned to the researchers who study rodent models of the disease and to those who study the cellular and molecular basis of human breast cancer. The first section of the book is devoted to new mouse models of mammary development and tumorigenesis. The second section moves to studies of human breast cancer and focuses on receptors, signalling, and the cell cycle. The final section deals with defective tissue interactions in human breast cancer. We are now in a period of extremely rapid accumulation of data on the molecular and cellular biology of breast cancer. These findings are highlighted in chapters from Mammary Tumor Cell Cycle, Differentiation and Metastasis: Advances in Cellular and Molecular Biology of Breast Cancer.
Download or read book Current Cancer Research on Cell Differentiation Tumor Growth Invasion and Metastasis written by and published by . This book was released on 1981 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Breast Cancer Biology written by Dil Afroze and published by BoD – Books on Demand. This book was released on 2020-07-08 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive overview of recent developments in the field of breast cancer biology. It is a complete and descriptive reference on motioning pathways and new treatment options for the future transnational scientists and clinicians working on cancer research and treatment. We greatly appreciate the work of all the contributors to this book. They have brought with them tremendous diversity of perspectives and fields, which is truly reflective of the complexity of the topic, and they have come together in this project to serve as the node of multidisciplinary collaboration in this field. Finally, we must acknowledge the thousands of cancer patients who have participated in the studies, and who have inspired us to gather information to significantly progress knowledge in the field in recent years.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Therapeutic potential of Cell Cycle Kinases in Breast Cancer written by Manzoor Mir and published by Springer Nature. This book was released on 2023-03-03 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the interrelation between cell cycle regulators and breast cancer phenotypes. It reviews the roles of Cyclin-Dependent Kinases (CDK) in driving cell cycle progression, cell cycle checkpoints and dysregulation in breast cancer. It also examines the prognostic significance of CDKs in breast cancer. and CDK inhibitors for the treatment of metastatic breast cancer. Further, the book discusses the role of different G1 cyclins in differentiation, chromosome stability, and transcriptional regulation in breast cancer. Additionally, it examines the role of immunogenic effects of CDK inhibitors, the mechanism of resistance and the current clinical trials in breast cancer treatment. Towards the end, the book explores cell cycle regulation as an attractive target for targeted drug therapy in breast cancer. This book is a comprehensive yet concise resource for oncologists and researchers interested in exploring the therapeutic potential of Cyclin-Dependent Kinases in breast cancer.
Download or read book Signal Transduction in Cancer Metastasis written by Wen-Sheng Wu and published by Springer Science & Business Media. This book was released on 2010-10-04 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the signal mechanisms responsible for triggering a series of phenotypical changes of primary tumor which may lead to final colonization of the tumor in a second home. It highlights the initial stage of tumor metastasis.
Download or read book Mammary Tumorigenesis and Malignant Progression written by Robert B. Dickson and published by Springer. This book was released on 1994-07-31 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current volume represents the fourth over a period of five years in our series on Advances in the Cellular and Molecular Biology of Breast Cancer. The first three volumes were entitled Breast Cancer: Cellular and Molecular Biology, Regulatory Mechanisms in Breast Cancer, and Genes, Oncogenes, and Hormones, respectively. Throughout this series, we have tried to take a broad look at cutting-edge topics in basic science research into breast cancer. This attempt has resulted in a wide range of subject material, including rodent and human model systems, oncogenes, suppressor genes, growth factors, hormones, tumor-host interactions, and determinants of metastases. Since our last volume, research in breast cancer has continued to proceed at an explosive rate. We hope the current volume will provide the reader with some of the excitement felt by the editors and authors as we begin to understand this all-too-common disease. The first section of this book is devoted to the basic processes of proli feration, differentiation, and malignant progression of breast cancer. T.l. Anderson and W.R. Miller lead off with a detailed description of controls on proliferation in the normal human breast and in breast cancer. This chapter strongly emphasizes pathological aspects. The second chapter, by M.R. Stampfer and P. Yaswen, presents a corresponding viewpoint through a presentation of experiments with human mammary epithelial cells in culture. The second section of the book emphasizes the genetic basis for breast cancer onset and malignant progression. Chapter 3, by M.-C. King and S.
Download or read book Regulatory Mechanisms in Breast Cancer written by Marc E. Lippman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Breast Cancer: Cellular and Molecular Biology [Kluwer Academic Pub lishers, 1988], we tried to present an introduction to the emerging basic studies on steroid receptors, oncogenes, and growth factors in the regulation of normal and malignant mammary epithelium. The response to this volume was superb, indicating a tremendous interest in basic growth regulatory mechanisms governing breast cancer and controlling its malignant progres sion. In the two years since its publication, much new and exciting in formation has been published and the full interplay of regulatory mechanisms is now beginning to emerge. We have divided this book into four sections that we hope will unify important concepts and help to crystallize areas of consensus and/or disagreement among a diverse group of basic and clinical scientists working on the disease. The first section is devoted to studies on oncogenes, antioncogenes, proliferation, and tumor prognosis. The first chapter, by Sunderland and McGuire, introduces the characteristics of breast cancer as studied by patho logists to establish prognostic outcome. Of particular interest is a new proto oncogene called HER-2 (or neu), which is rapidly becoming accepted as a valuable new tumor marker of poor prognosis. The second chapter, by Lee Bookstein and Lee, introduces the best known antioncogene, the retinoblas toma antioncogene, whose expression is sometimes lost in breast cancer. Malignant progression appears to be influenced by the balance of proto oncogene and antioncogene expression.
Download or read book Cell and Molecular Biology of Breast Cancer written by Heide Schatten and published by Springer Science & Business Media. This book was released on 2013-09-27 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highlighting recent advances in our understanding of breast cancer, this book is intended for a wide audience as a reference book. Included are reviews of genetics, epigenetics, various aspects of cell and molecular biology, and several other areas of breast cancer that are aimed at determining new intervention sites for treatments and cures of the disease. The chapters are written by internationally recognized experts and include reviews of key topics in breast cancer research. Each chapter highlights the new aspects of specific research topics and the various impacts of designing new strategies as well as identifies new targets for therapeutic intervention. The topics addressed are selected to be of interest to patients, scientists, students, teachers, and anyone else interested in expanding their knowledge of breast cancer imaging, diagnostics, therapeutics, or basic biomedical research on breast cancer.
Download or read book Perspectives in Mammary Gland Development and Breast Cancer Research written by Zuzana Koledova and published by Frontiers Media SA. This book was released on 2020-10-27 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book Tumor Dormancy Quiescence and Senescence Volume 1 written by M.A. Hayat and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a particular emphasis on tumor dormancy in breast, lung, prostate, and liver cancers, as well as in melanoma, this first volume of a new Springer series focuses on the interrelationship between biological processes of aging and tumors—both dormant and quiescent. With detail supplied by numerous international researchers at the forefront of cancer research, the book examines a host of differing aspects of the topic. Featured contributions analyze the role of the quiescent state in regulating hematopoietic and muscle stem cells. They also explore the mediation, by the kinase, in the reversible quiescent state of a subset of ovarian, pancreatic, and colon cancers. The book includes key research on the molecular mechanisms underlying stress-induced cellular senescence, in addition to those governing the accumulation of reactive oxygen species, and the induction of premature senescence. It also provides information on suppressing cellular senescence in the most common, and most aggressive malignant primary brain tumor in humans, glioblastoma multiforme. With comprehensive and cutting-edge information on therapeutic interventions and on the correct diagnosis of relevant neoplasms, and with numerous color illustrations, this is the most up-to-date assessment of current medical knowledge in this crucial area of medical research.
Download or read book MAMMALIAN TUMOR CELL HETEROGENEITY written by John T. Leith and published by Springer. This book was released on 1986-02 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Introduction to Tumor Biology written by I. De Wever and published by Leuven University Press. This book was released on 1999 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers clinical oncologists an introduction to some selected topics of tumor biology where important progress has been made during the last decade. The concept is rather unique because it combines advances in clinical pathology, genetics, molecular oncology and immunology.The first two chapters deal with the genetic and molecular basis of malignant transformation on cellular level: DNA damage, mutations and repair mechanisms, oncogenes and tumor suppressor genes. The growth of a tumor cell population depends not only on cell division, but also on deregulation of apoptosis (chapter 3). Most clinical tumors are charcterised by heterogeneity caused by different degrees of differentiation in different cell clones as illustrated for soft tissue tumors in chapter 4. The following chapters explain the multistep process of local tumor progression in gastro-intestinal cancers and malignant melanoma. Cellular and molucular aspects of metastases are dealt with in chapter 7. But host cells react to tumor cells and specific T-cell defined antigens offer a perspective for cancer vaccine development as reviewed in the last chatper.The book is timely because new diagnostic and therapeutic applications based on molecular oncology will reach the clinic at ever increasing pace.
Download or read book The Biological Basis of Cancer written by Robert G. McKinnell and published by Cambridge University Press. This book was released on 1998-03-13 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new textbook, designed for undergraduates taking a cancer course, covering everything from the molecular to the clinical aspects of the subject.
Download or read book Cancer Stem Cells written by Stanley Shostak and published by BoD – Books on Demand. This book was released on 2011-03-22 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Stem Cells Theories and Practice does not 'boldly go where no one has gone before!' Rather, Cancer Stem Cells Theories and Practice boldly goes where the cutting edge of research theory meets the concrete challenges of clinical practice. Cancer Stem Cells Theories and Practice is firmly grounded in the latest results on cancer stem cells (CSCs) from world-class cancer research laboratories, but its twenty-two chapters also tease apart cancer's vulnerabilities and identify opportunities for early detection, targeted therapy, and reducing remission and resistance.
Download or read book The Genetics of Cancer written by Gajanan V. Sherbet and published by Academic Press. This book was released on 1997-06-22 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by internationally recognized experts, The Genetics of Cancer provides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes in the pathogenesis and progression of cancer. The Genetics of Cancer will be useful to all graduate students, clinicians, and researchers working in the fields of cancer biology, genetics, and molecular biology. Clonal evolution of the metastasis phenotype Cell Cycle regulation Apoptosis in tumour growth and metastasis Angiogenesis in cancer Cell surface glycoproteins and their receptors Proteinases and their inhibitors in cancer invasion Oncogenes and cancer metastasis Developmental genes Tumour suppressor genes Metastasis suppressor genes Dominant metastasis-associated genes
