Download or read book Macromolecules and the function of the neuren written by Zdeněk Lodin and published by . This book was released on 1968 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Macromolecules and the Function of the Neuron written by Zdeněk Lodin and published by . This book was released on 1968 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book MacRomolecules and the Function of the Neuron written by Lodin and published by . This book was released on 1968 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Handbook of Neuroprotection written by Kewal K. Jain and published by Springer. This book was released on 2019-05-15 with total page 857 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully revised edition explores the management of neurological disorders with a focus on neuroprotection, disease modification, and neuroregeneration rather than symptomatic treatment. Since the publication of the first edition, advances in biotechnology, particularly in cell and gene therapies, are reflected in this volume, as are numerous new and repurposed drugs in clinical trials. Overall, The Handbook of Neuroprotection serves as a comprehensive review of neuroprotection based on knowledge of the molecular basis of disorders of the central nervous system. In-depth and authoritative, The Handbook of Neuroprotection, Second Edition features a compendium of vital knowledge aimed at providing researchers with an essential reference for this key neurological area of study.
Download or read book Modern Methods of Drug Discovery written by Alexander Hillisch and published by Birkhäuser. This book was released on 2012-11-28 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in the pharmaceutical industry today is in many respects quite different from what it used to be only fifteen years ago. There have been dramatic changes in approaches for identifying new chemical entities with a desired biological activity. While chemical modification of existing leads was the most important approach in the 1970s and 1980s, high-throughput screening and structure-based design are now major players among a multitude of methods used in drug discov ery. Quite often, companies favor one of these relatively new approaches over the other, e.g., screening over rational design, or vice versa, but we believe that an intelligent and concerted use of several or all methods currently available to drug discovery will be more successful in the medium term. What has changed most significantly in the past few years is the time available for identifying new chemical entities. Because of the high costs of drug discovery projects, pressure for maximum success in the shortest possible time is higher than ever. In addition, the multidisciplinary character of the field is much more pronounced today than it used to be. As a consequence, researchers and project managers in the pharmaceutical industry should have a solid knowledge of the more important methods available to drug discovery, because it is the rapidly and intelligently combined use of these which will determine the success or failure of preclinical projects.
Download or read book Occult Spinal Dysraphism written by R. Shane Tubbs and published by Springer. This book was released on 2019-03-14 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the known details of all subtypes of occult spinal dysraphism in unprecedented detail. This 21 chapter invaluable resource begins with a deep dive into the history and embryology of occult spinal dysraphisms. Following this, subtypes of occult spinal dysraphism are thoroughly explored — of which include split cord malformations, tethered cord syndromes, adult presentations/outcomes of occult spinal dysraphism, cutaneous stigmata. Chapters will cover the clinical presentation, radiological features, and surgical nuances of each of the occult spinal dysraphisms. Throughout the book, expertly written text is supplemented by a number of high quality figures and tables, as well as a video documenting surgical treatment of type 1 split cord malformation. By focusing on each entity currently grouped within this topic as a separate chapter, the most up-to-date information will be provided to the reader, making Occult Spinal Dysraphism a must-have resource for students, practitioners and medical professionals involved in treating spinal dsyraphism.
Download or read book FXTAS FXPOI and Other Premutation Disorders written by Flora Tassone and published by Springer. This book was released on 2016-11-17 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book should serve as a resource for professionals in all fields regarding diagnosis, management, and counseling of patients with FXTAS, FXPOI and their families, as well as presenting the molecular basis for disease that may lead to the identification of new markers to predict disease risk and eventually lead to target treatments. The book will present information on all aspects of FXTAS, FXPOI and other premutation disorders including clinical features and current supportive management, radiological, psychological, and pathological findings, genotype-phenotype relationships, animal models and basic molecular mechanisms. Genetic counseling issues are also discussed.
Download or read book Spine Imaging written by Brian C. Bowen and published by . This book was released on 2001 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the popular Case Review series, SPINE IMAGING: CASE REVIEW focuses on imaging of the spine, complete with full discussion and images. Designed as a study guide for radiology and neuroradiology residents preparing for board exams and clinical practice, it presents 175 unknown cases in which clinical images (MR, CT, plain radiographs, angiograms, myelograms) of spinal pathology, as well as anatomic variants, are discussed. It contains more than 350 images with questions, answers, commentary, references, and cross references to NEURORADIOLOGY: THE REQUISITES by Grossman. * Features at-a-glance review of spine imaging cases that can prepare the candidate studying for exams in Neuroradiology or for the general radiologist looking for the ideal tool to help sharpen diagnostic abilities in this subspecialty. * Mimics official exam formats and allows reader self-testing, subsequent learning, preparation and confidence-building to succeed in exam settings and in the daily practice environment. * Organizes cases randomly and divides them into three overall categories, so the reader has the opportunity to test him/herself at different degrees of difficulty. * Complements and references the Neuroradiology: THE REQUISITES volume to provide the most comprehensive review for the exams. THE REQUISITES covers the essentials of the subspecialty and the CASE REVIEW allows you to test yourself on those essentials. * Includes approximately 400 state-of-the-art images which complement the text and provide a clear picture of what exam takers can expect. * Affordable, manageable, practical 8 1/2 x 11 size with space for note-taking in the text. * Features a consistent format with the same features: case presented as unknown with four questions, followed by answers to questions, detailed commentary, latest references in the literature, and cross-reference to THE REQUISITES volume.
Download or read book Neuro Oncology The Essentials written by Mark Bernstein and published by Thieme. This book was released on 2011-01-01 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Neuro-Oncology: The Essentials presents a comprehensive, highly readable introduction to the fundamental science and core clinical concepts for successfully managing common problems in neuro-oncology. Tightly focused chapters provide up-to-date systematic coverage of biology, imaging, surgery, radiation, chemotherapy, and biological concepts. The book addresses specific tumor types in separate chapters, providing detailed discussion of background, incidence, clinical features, management, surgical approaches, recurrence, and outcomes.Highlights: Pearls, pitfalls, controversies, and special considerations in textboxes -- ideal for rapidly reviewing key points More than 250 photographs and illustrations demonstrate important concepts This book is an invaluable reference for neurosurgeons, neurologists, oncologists, residents and fellows in these specialties, as well as for students.
Download or read book The Scar Book written by Andrew C. Krakowski and published by Lippincott Williams & Wilkins. This book was released on 2017-02-08 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: Apply cutting-edge expertise to manage your patients’ scarring issues! Scarring and fibrosis affect millions of people worldwide, and can be devastating both physically and psychologically, whether they result from major trauma such as burns or common conditions such as acne. Put today’s most advanced clinical approaches to work for your patients with The Scar Book: Formation, Mitigation, Rehabilitation, and Prevention! A multidisciplinary team of leading world experts presents the state of the art in scar pathophysiology and treatment, breaking down the barriers between medical disciplines to provide unprecedented holistic guidance.
Download or read book Structure Determination from Powder Diffraction Data written by William I. F. David and published by OUP Oxford. This book was released on 2002 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of the properties of materials, from drugs and proteins to catalysts and ceramics, is almost always based on structural information. This book describes the new developments in the realm of powder diffraction which make it possible for scientists to obtain such information even from polycrystalline materials. Written and edited by experts active in the field, and covering both the fundamental and applied aspects of structure solution from powder diffraction data, this book guides both novices and experienced practitioners alike through the maze of possibilities.
Download or read book Iminosugars written by Philippe Compain and published by John Wiley & Sons. This book was released on 2007-10-22 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iminosugars form undoubtedly the most attractive of carbohydrate mimics reported so far. In these structures, the substitution of the endocyclic oxygen of sugars by a basic nitrogen atom leads to remarkable biological properties and raises many challenges in organic synthesis. Since the discovery of their biological activity as glycosidase inhibitors in the 1970’s, these polyvalent molecules have progressively made their way from the laboratory to the clinic. The impressive series of discoveries in the field over the past ten years indicates clearly that it is “a boom time” for iminosugar chemistry and biology. The scope of their profile as inhibitors has been extended to a number of enzymes such as phosphorylases, glycosyltransferases or metalloproteinases, and iminosugars now constitute lead compounds for the development of new therapeutic agents for a wide range of diseases including diabetes, viral infections, lysosomal storage disorders and tumor metastasis. Latest developments, from iminosugar synthesis to their use in clinical studies, are presented in this book, which contains contributions from over fifteen of the major chemists, biochemists and drug developers in this rapidly expanding field. An extensive table correlating the structures of more than 600 iminosugars of therapeutic interest with their biological activities is also included in the book and should prove particularly useful to aid with the design and the discovery of novel bioactive substances. Iminosugars: From Synthesis to Therapeutic Application provides a unique resource for academic and industrial researchers working in the field of iminosugars and glycomimetics of biological and/or therapeutic interest: organic chemists, medicinal chemists, carbohydrate chemists and medical scientists.
Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1972 with total page 1132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Light and Biological Rhythms in Man written by L. Wetterberg and published by Elsevier. This book was released on 2014-06-28 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, current knowledge on light as a regulator of biological rhythms is considered from both basic science and clinical perspectives. Chapters by leading experts cover the whole range of biological rhythms, from infradian and circadian to the longer ultradian rhythms, in a wide variety of mammalian species. The chapters on humans provide a basis on which to establish mechanisms for mediating the therapeutic and physiologically beneficial effects of light as a regulator of rhythms in health and disease.
Download or read book Membranes and Molecular Assemblies written by Jurgen-Hinrich Fuhrhop and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supramolecular chemistry concerns the structure and function of molecular assemblies formed through weak interactions. These complexes have found diverse applications in materials chemistry, nanoscience, catalysis, food sciences and medicine, and this has led to a rapid expansion in supramolecular chemistry research. With contributions from high profile international scientists working within the field, each book in the series covers a key concept for graduate level students and above interested in supramolecular chemistry and its diverse applications. The books are ideal for reference and as state-of-the art guides, and they aim to enable further developments of new applications through an understanding of the fundamentals and a comprehensive overview of the latest research.
Download or read book Peptides and Peptide based Biomaterials and their Biomedical Applications written by Anwar Sunna and published by Springer. This book was released on 2017-10-26 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid-binding peptides have been used increasingly as molecular building blocks in nanobiotechnology as they can direct the assembly and functionalisation of a diverse range of materials and have the ability to regulate the synthesis of nanoparticles and complex nanostructures. Nanostructured materials such as β-sheet fibril-forming peptides and α-helical coiled coil systems have displayed many useful properties including stimulus-responsiveness, modularity and multi-functionality, providing potential technological applications in tissue engineering, antimicrobials, drug delivery and nanoscale electronics. The current situation with respect to self-assembling peptides and bioactive matrices for regenerative medicine are reviewed, as well as peptide-target modeling and an examination of future prospects for peptides in these areas.
Download or read book Spine Imaging E Book written by Brian C. Bowen and published by Elsevier Health Sciences. This book was released on 2008-01-22 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume in the best-selling "Case Review" series uses nearly 200 case studies to challenge your knowledge on a full range of topics in spine imaging. Each case includes a set of 1 to 4 unknown images and four self-test questions, accompanied by answers, supporting literature references, and a commentary to help you gain a better understanding of how the correct diagnosis was reached. The discussion addresses the most important imaging, pathological, and clinical features of the case. This unique case-based format - coupled with an easy-access organization and high-quality images - equips you with the guidance you need to master the material, pass certification exams, and succeed in practice. Serves as a useful preparation tool for certification review with its unique case-based format that mimics the actual exam. Illustrates many nondegenerative diseases of the spine, such as congenital, vascular, neoplastic, inflammatory/infectious, and traumatic cases, including abnormal imaging findings. Covers diseases involving spinal nerves and paraspinal plexuses, facilitating recognition of entities such as hereditary peripheral neuropathies and the perineural spread of neoplastic disease. Offers more than 400 high-quality, state-of-the-art images - most new to this edition - representing a wide range of clinical situations encountered in the field. Features cases at three different levels of difficulty: Opening Round, Fair Game, and Challenge to test the knowledge of any practitioners, regardless of degree or experience. Presents new and expanded coverage of vascular lesions · vetebral lesions · lesions of spinal/peripheral nerves · MR/CT techniques · and more. Features completely new figures as part of 120 new and existing cases. Includes cross references of every case to Grossman & Yousem text, Neuroradiology: The Requisites, 2nd Edition.
