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Book Machine Learning in Medicine     A Complete Overview

Download or read book Machine Learning in Medicine A Complete Overview written by Ton J. Cleophas and published by Springer Nature. This book was released on 2020-03-03 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adequate health and health care is no longer possible without proper data supervision from modern machine learning methodologies like cluster models, neural networks, and other data mining methodologies. The current book is the first publication of a complete overview of machine learning methodologies for the medical and health sector, and it was written as a training companion, and as a must-read, not only for physicians and students, but also for any one involved in the process and progress of health and health care. In this second edition the authors have removed the textual errors from the first edition. Also, the improved tables from the first edition, have been replaced with the original tables from the software programs as applied. This is, because, unlike the former, the latter were without error, and readers were better familiar with them. The main purpose of the first edition was, to provide stepwise analyses of the novel methods from data examples, but background information and clinical relevance information may have been somewhat lacking. Therefore, each chapter now contains a section entitled "Background Information". Machine learning may be more informative, and may provide better sensitivity of testing than traditional analytic methods may do. In the second edition a place has been given for the use of machine learning not only to the analysis of observational clinical data, but also to that of controlled clinical trials. Unlike the first edition, the second edition has drawings in full color providing a helpful extra dimension to the data analysis. Several machine learning methodologies not yet covered in the first edition, but increasingly important today, have been included in this updated edition, for example, negative binomial and Poisson regressions, sparse canonical analysis, Firth's bias adjusted logistic analysis, omics research, eigenvalues and eigenvectors.

Book Machine Learning in Medicine   a Complete Overview

Download or read book Machine Learning in Medicine a Complete Overview written by Ton J. Cleophas and published by Springer. This book was released on 2016-10-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current book is the first publication of a complete overview of machine learning methodologies for the medical and health sector. It was written as a training companion and as a must-read, not only for physicians and students, but also for any one involved in the process and progress of health and health care. In eighty chapters eighty different machine learning methodologies are reviewed, in combination with data examples for self-assessment. Each chapter can be studied without the need to consult other chapters. The amount of data stored in the world's databases doubles every 20 months, and clinicians, familiar with traditional statistical methods, are at a loss to analyze them. Traditional methods have, indeed, difficulty to identify outliers in large datasets, and to find patterns in big data and data with multiple exposure / outcome variables. In addition, analysis-rules for surveys and questionnaires, which are currently common methods of data collection, are, essentially, missing. Fortunately, the new discipline, machine learning, is able to cover all of these limitations. So far medical professionals have been rather reluctant to use machine learning. Also, in the field of diagnosis making, few doctors may want a computer checking them, are interested in collaboration with a computer or with computer engineers. Adequate health and health care will, however, soon be impossible without proper data supervision from modern machine learning methodologies like cluster models, neural networks and other data mining methodologies. Each chapter starts with purposes and scientific questions. Then, step-by-step analyses, using data examples, are given. Finally, a paragraph with conclusion, and references to the corresponding sites of three introductory textbooks, previously written by the same authors, is given.

Book Artificial Intelligence in Healthcare

Download or read book Artificial Intelligence in Healthcare written by Adam Bohr and published by Academic Press. This book was released on 2020-06-21 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. Highlights different data techniques in healthcare data analysis, including machine learning and data mining Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks Includes applications and case studies across all areas of AI in healthcare data

Book Deep Medicine

    Book Details:
  • Author : Eric Topol
  • Publisher : Basic Books
  • Release : 2019-03-12
  • ISBN : 1541644646
  • Pages : 373 pages

Download or read book Deep Medicine written by Eric Topol and published by Basic Books. This book was released on 2019-03-12 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Science Friday pick for book of the year, 2019 One of America's top doctors reveals how AI will empower physicians and revolutionize patient care Medicine has become inhuman, to disastrous effect. The doctor-patient relationship--the heart of medicine--is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality. By freeing physicians from the tasks that interfere with human connection, AI will create space for the real healing that takes place between a doctor who can listen and a patient who needs to be heard. Innovative, provocative, and hopeful, Deep Medicine shows us how the awesome power of AI can make medicine better, for all the humans involved.

Book Machine Learning for Healthcare Applications

Download or read book Machine Learning for Healthcare Applications written by Sachi Nandan Mohanty and published by John Wiley & Sons. This book was released on 2021-04-13 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: When considering the idea of using machine learning in healthcare, it is a Herculean task to present the entire gamut of information in the field of intelligent systems. It is, therefore the objective of this book to keep the presentation narrow and intensive. This approach is distinct from others in that it presents detailed computer simulations for all models presented with explanations of the program code. It includes unique and distinctive chapters on disease diagnosis, telemedicine, medical imaging, smart health monitoring, social media healthcare, and machine learning for COVID-19. These chapters help develop a clear understanding of the working of an algorithm while strengthening logical thinking. In this environment, answering a single question may require accessing several data sources and calling on sophisticated analysis tools. While data integration is a dynamic research area in the database community, the specific needs of research have led to the development of numerous middleware systems that provide seamless data access in a result-driven environment. Since this book is intended to be useful to a wide audience, students, researchers and scientists from both academia and industry may all benefit from this material. It contains a comprehensive description of issues for healthcare data management and an overview of existing systems, making it appropriate for introductory and instructional purposes. Prerequisites are minimal; the readers are expected to have basic knowledge of machine learning. This book is divided into 22 real-time innovative chapters which provide a variety of application examples in different domains. These chapters illustrate why traditional approaches often fail to meet customers’ needs. The presented approaches provide a comprehensive overview of current technology. Each of these chapters, which are written by the main inventors of the presented systems, specifies requirements and provides a description of both the chosen approach and its implementation. Because of the self-contained nature of these chapters, they may be read in any order. Each of the chapters use various technical terms which involve expertise in machine learning and computer science.

Book Machine Learning and the Internet of Medical Things in Healthcare

Download or read book Machine Learning and the Internet of Medical Things in Healthcare written by Krishna Kant Singh and published by Academic Press. This book was released on 2021-04-14 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine Learning and the Internet of Medical Things in Healthcare discusses the applications and challenges of machine learning for healthcare applications. The book provides a platform for presenting machine learning-enabled healthcare techniques and offers a mathematical and conceptual background of the latest technology. It describes machine learning techniques along with the emerging platform of the Internet of Medical Things used by practitioners and researchers worldwide. The book includes deep feed forward networks, regularization, optimization algorithms, convolutional networks, sequence modeling, and practical methodology. It also presents the concepts of the Internet of Things, the set of technologies that develops traditional devices into smart devices. Finally, the book offers research perspectives, covering the convergence of machine learning and IoT. It also presents the application of these technologies in the development of healthcare frameworks. Provides an introduction to the Internet of Medical Things through the principles and applications of machine learning Explains the functions and applications of machine learning in various applications such as ultrasound imaging, biomedical signal processing, robotics, and biomechatronics Includes coverage of the evolution of healthcare applications with machine learning, including Clinical Decision Support Systems, artificial intelligence in biomedical engineering, and AI-enabled connected health informatics, supported by real-world case studies

Book Introduction to Deep Learning for Healthcare

Download or read book Introduction to Deep Learning for Healthcare written by Cao Xiao and published by Springer Nature. This book was released on 2021-11-11 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook presents deep learning models and their healthcare applications. It focuses on rich health data and deep learning models that can effectively model health data. Healthcare data: Among all healthcare technologies, electronic health records (EHRs) had vast adoption and a significant impact on healthcare delivery in recent years. One crucial benefit of EHRs is to capture all the patient encounters with rich multi-modality data. Healthcare data include both structured and unstructured information. Structured data include various medical codes for diagnoses and procedures, lab results, and medication information. Unstructured data contain 1) clinical notes as text, 2) medical imaging data such as X-rays, echocardiogram, and magnetic resonance imaging (MRI), and 3) time-series data such as the electrocardiogram (ECG) and electroencephalogram (EEG). Beyond the data collected during clinical visits, patient self-generated/reported data start to grow thanks to wearable sensors’ increasing use. The authors present deep learning case studies on all data described. Deep learning models: Neural network models are a class of machine learning methods with a long history. Deep learning models are neural networks of many layers, which can extract multiple levels of features from raw data. Deep learning applied to healthcare is a natural and promising direction with many initial successes. The authors cover deep neural networks, convolutional neural networks, recurrent neural networks, embedding methods, autoencoders, attention models, graph neural networks, memory networks, and generative models. It’s presented with concrete healthcare case studies such as clinical predictive modeling, readmission prediction, phenotyping, x-ray classification, ECG diagnosis, sleep monitoring, automatic diagnosis coding from clinical notes, automatic deidentification, medication recommendation, drug discovery (drug property prediction and molecule generation), and clinical trial matching. This textbook targets graduate-level students focused on deep learning methods and their healthcare applications. It can be used for the concepts of deep learning and its applications as well. Researchers working in this field will also find this book to be extremely useful and valuable for their research.

Book Artificial Intelligence in Medicine

Download or read book Artificial Intelligence in Medicine written by David Riaño and published by Springer. This book was released on 2019-06-19 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 17th Conference on Artificial Intelligence in Medicine, AIME 2019, held in Poznan, Poland, in June 2019. The 22 revised full and 31 short papers presented were carefully reviewed and selected from 134 submissions. The papers are organized in the following topical sections: deep learning; simulation; knowledge representation; probabilistic models; behavior monitoring; clustering, natural language processing, and decision support; feature selection; image processing; general machine learning; and unsupervised learning.

Book Fundamentals of Machine Learning and Deep Learning in Medicine

Download or read book Fundamentals of Machine Learning and Deep Learning in Medicine written by Reza Borhani and published by Springer Nature. This book was released on 2022-11-18 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an accessible introduction to the foundations of machine learning and deep learning in medicine for medical students, researchers, and professionals who are not necessarily initiated in advanced mathematics but yearn for a better understanding of this disruptive technology and its impact on medicine. Once an esoteric subject known to few outside of computer science and engineering departments, today artificial intelligence (AI) is a widely popular technology used by scholars from all across the academic universe. In particular, recent years have seen a great deal of interest in the AI subfields of machine learning and deep learning from researchers in medicine and life sciences, evidenced by the rapid growth in the number of articles published on the topic in peer-reviewed medical journals over the last decade. The demand for high-quality educational resources in this area has never been greater than it is today, and will only continue to grow at a rapid pace. Expert authors remove the veil of unnecessary complexity that often surrounds machine learning and deep learning by employing a narrative style that emphasizes intuition in place of abstract mathematical formalisms, allowing them to strike a delicate balance between practicality and theoretical rigor in service of facilitating the reader’s learning experience. Topics covered in the book include: mathematical encoding of medical data, linear regression and classification, nonlinear feature engineering, deep learning, convolutional and recurrent neural networks, and reinforcement learning. Each chapter ends with a collection of exercises for readers to practice and test their knowledge. This is an ideal introduction for medical students, professionals, and researchers interested in learning more about machine learning and deep learning. Readers who have taken at least one introductory mathematics course at the undergraduate-level (e.g., biostatistics or calculus) will be well-equipped to use this book without needing any additional prerequisites.

Book Machine Learning in Cardiovascular Medicine

Download or read book Machine Learning in Cardiovascular Medicine written by Subhi J. Al'Aref and published by Academic Press. This book was released on 2020-11-20 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine Learning in Cardiovascular Medicine addresses the ever-expanding applications of artificial intelligence (AI), specifically machine learning (ML), in healthcare and within cardiovascular medicine. The book focuses on emphasizing ML for biomedical applications and provides a comprehensive summary of the past and present of AI, basics of ML, and clinical applications of ML within cardiovascular medicine for predictive analytics and precision medicine. It helps readers understand how ML works along with its limitations and strengths, such that they can could harness its computational power to streamline workflow and improve patient care. It is suitable for both clinicians and engineers; providing a template for clinicians to understand areas of application of machine learning within cardiovascular research; and assist computer scientists and engineers in evaluating current and future impact of machine learning on cardiovascular medicine. Provides an overview of machine learning, both for a clinical and engineering audience Summarize recent advances in both cardiovascular medicine and artificial intelligence Discusses the advantages of using machine learning for outcomes research and image processing Addresses the ever-expanding application of this novel technology and discusses some of the unique challenges associated with such an approach

Book Demystifying Big Data and Machine Learning for Healthcare

Download or read book Demystifying Big Data and Machine Learning for Healthcare written by Prashant Natarajan and published by CRC Press. This book was released on 2017-02-15 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthcare transformation requires us to continually look at new and better ways to manage insights – both within and outside the organization today. Increasingly, the ability to glean and operationalize new insights efficiently as a byproduct of an organization’s day-to-day operations is becoming vital to hospitals and health systems ability to survive and prosper. One of the long-standing challenges in healthcare informatics has been the ability to deal with the sheer variety and volume of disparate healthcare data and the increasing need to derive veracity and value out of it. Demystifying Big Data and Machine Learning for Healthcare investigates how healthcare organizations can leverage this tapestry of big data to discover new business value, use cases, and knowledge as well as how big data can be woven into pre-existing business intelligence and analytics efforts. This book focuses on teaching you how to: Develop skills needed to identify and demolish big-data myths Become an expert in separating hype from reality Understand the V’s that matter in healthcare and why Harmonize the 4 C’s across little and big data Choose data fi delity over data quality Learn how to apply the NRF Framework Master applied machine learning for healthcare Conduct a guided tour of learning algorithms Recognize and be prepared for the future of artificial intelligence in healthcare via best practices, feedback loops, and contextually intelligent agents (CIAs) The variety of data in healthcare spans multiple business workflows, formats (structured, un-, and semi-structured), integration at point of care/need, and integration with existing knowledge. In order to deal with these realities, the authors propose new approaches to creating a knowledge-driven learning organization-based on new and existing strategies, methods and technologies. This book will address the long-standing challenges in healthcare informatics and provide pragmatic recommendations on how to deal with them.

Book Machine Learning in Medicine

    Book Details:
  • Author : Ton J. Cleophas
  • Publisher : Springer Science & Business Media
  • Release : 2013-05-30
  • ISBN : 9400768869
  • Pages : 235 pages

Download or read book Machine Learning in Medicine written by Ton J. Cleophas and published by Springer Science & Business Media. This book was released on 2013-05-30 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine learning is concerned with the analysis of large data and multiple variables. However, it is also often more sensitive than traditional statistical methods to analyze small data. The first volume reviewed subjects like optimal scaling, neural networks, factor analysis, partial least squares, discriminant analysis, canonical analysis, and fuzzy modeling. This second volume includes various clustering models, support vector machines, Bayesian networks, discrete wavelet analysis, genetic programming, association rule learning, anomaly detection, correspondence analysis, and other subjects. Both the theoretical bases and the step by step analyses are described for the benefit of non-mathematical readers. Each chapter can be studied without the need to consult other chapters. Traditional statistical tests are, sometimes, priors to machine learning methods, and they are also, sometimes, used as contrast tests. To those wishing to obtain more knowledge of them, we recommend to additionally study (1) Statistics Applied to Clinical Studies 5th Edition 2012, (2) SPSS for Starters Part One and Two 2012, and (3) Statistical Analysis of Clinical Data on a Pocket Calculator Part One and Two 2012, written by the same authors, and edited by Springer, New York.

Book Machine Learning in Medicine

Download or read book Machine Learning in Medicine written by Ayman El-Baz and published by CRC Press. This book was released on 2021-08-04 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine Learning in Medicine covers the state-of-the-art techniques of machine learning and their applications in the medical field. It presents several computer-aided diagnosis (CAD) systems, which have played an important role in the diagnosis of several diseases in the past decade, e.g., cancer detection, resulting in the development of several successful systems. New developments in machine learning may make it possible in the near future to develop machines that are capable of completely performing tasks that currently cannot be completed without human aid, especially in the medical field. This book covers such machines, including convolutional neural networks (CNNs) with different activation functions for small- to medium-size biomedical datasets, detection of abnormal activities stemming from cognitive decline, thermal dose modelling for thermal ablative cancer treatments, dermatological machine learning clinical decision support systems, artificial intelligence-powered ultrasound for diagnosis, practical challenges with possible solutions for machine learning in medical imaging, epilepsy diagnosis from structural MRI, Alzheimer's disease diagnosis, classification of left ventricular hypertrophy, and intelligent medical language understanding. This book will help to advance scientific research within the broad field of machine learning in the medical field. It focuses on major trends and challenges in this area and presents work aimed at identifying new techniques and their use in biomedical analysis, including extensive references at the end of each chapter.

Book Fundamentals and Methods of Machine and Deep Learning

Download or read book Fundamentals and Methods of Machine and Deep Learning written by Pradeep Singh and published by John Wiley & Sons. This book was released on 2022-02-01 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: FUNDAMENTALS AND METHODS OF MACHINE AND DEEP LEARNING The book provides a practical approach by explaining the concepts of machine learning and deep learning algorithms, evaluation of methodology advances, and algorithm demonstrations with applications. Over the past two decades, the field of machine learning and its subfield deep learning have played a main role in software applications development. Also, in recent research studies, they are regarded as one of the disruptive technologies that will transform our future life, business, and the global economy. The recent explosion of digital data in a wide variety of domains, including science, engineering, Internet of Things, biomedical, healthcare, and many business sectors, has declared the era of big data, which cannot be analysed by classical statistics but by the more modern, robust machine learning and deep learning techniques. Since machine learning learns from data rather than by programming hard-coded decision rules, an attempt is being made to use machine learning to make computers that are able to solve problems like human experts in the field. The goal of this book is to present a??practical approach by explaining the concepts of machine learning and deep learning algorithms with applications. Supervised machine learning algorithms, ensemble machine learning algorithms, feature selection, deep learning techniques, and their applications are discussed. Also included in the eighteen chapters is unique information which provides a clear understanding of concepts by using algorithms and case studies illustrated with applications of machine learning and deep learning in different domains, including disease prediction, software defect prediction, online television analysis, medical image processing, etc. Each of the chapters briefly described below provides both a chosen approach and its implementation. Audience Researchers and engineers in artificial intelligence, computer scientists as well as software developers.

Book Machine Learning and AI for Healthcare

Download or read book Machine Learning and AI for Healthcare written by Arjun Panesar and published by Apress. This book was released on 2019-02-04 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore the theory and practical applications of artificial intelligence (AI) and machine learning in healthcare. This book offers a guided tour of machine learning algorithms, architecture design, and applications of learning in healthcare and big data challenges. You’ll discover the ethical implications of healthcare data analytics and the future of AI in population and patient health optimization. You’ll also create a machine learning model, evaluate performance and operationalize its outcomes within your organization. Machine Learning and AI for Healthcare provides techniques on how to apply machine learning within your organization and evaluate the efficacy, suitability, and efficiency of AI applications. These are illustrated through leading case studies, including how chronic disease is being redefined through patient-led data learning and the Internet of Things. What You'll LearnGain a deeper understanding of key machine learning algorithms and their use and implementation within wider healthcare Implement machine learning systems, such as speech recognition and enhanced deep learning/AI Select learning methods/algorithms and tuning for use in healthcare Recognize and prepare for the future of artificial intelligence in healthcare through best practices, feedback loops and intelligent agentsWho This Book Is For Health care professionals interested in how machine learning can be used to develop health intelligence – with the aim of improving patient health, population health and facilitating significant care-payer cost savings.

Book Deep Learning in Healthcare

Download or read book Deep Learning in Healthcare written by Yen-Wei Chen and published by Springer Nature. This book was released on 2019-11-18 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of deep learning (DL) in medical and healthcare applications, including the fundamentals and current advances in medical image analysis, state-of-the-art DL methods for medical image analysis and real-world, deep learning-based clinical computer-aided diagnosis systems. Deep learning (DL) is one of the key techniques of artificial intelligence (AI) and today plays an important role in numerous academic and industrial areas. DL involves using a neural network with many layers (deep structure) between input and output, and its main advantage of is that it can automatically learn data-driven, highly representative and hierarchical features and perform feature extraction and classification on one network. DL can be used to model or simulate an intelligent system or process using annotated training data. Recently, DL has become widely used in medical applications, such as anatomic modelling, tumour detection, disease classification, computer-aided diagnosis and surgical planning. This book is intended for computer science and engineering students and researchers, medical professionals and anyone interested using DL techniques.

Book Machine Learning in Medicine   Cookbook Two

Download or read book Machine Learning in Medicine Cookbook Two written by Ton J. Cleophas and published by Springer. This book was released on 2014-05-27 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: The amount of data medical databases doubles every 20 months, and physicians are at a loss to analyze them. Also, traditional data analysis has difficulty to identify outliers and patterns in big data and data with multiple exposure / outcome variables and analysis-rules for surveys and questionnaires, currently common methods of data collection, are, essentially, missing. Consequently, proper data-based health decisions will soon be impossible. Obviously, it is time that medical and health professionals mastered their reluctance to use machine learning methods and this was the main incentive for the authors to complete a series of three textbooks entitled “Machine Learning in Medicine Part One, Two and Three, Springer Heidelberg Germany, 2012-2013", describing in a nonmathematical way over sixty machine learning methodologies, as available in SPSS statistical software and other major software programs. Although well received, it came to our attention that physicians and students often lacked time to read the entire books, and requested a small book, without background information and theoretical discussions and highlighting technical details. For this reason we produced a 100 page cookbook, entitled "Machine Learning in Medicine - Cookbook One", with data examples available at extras.springer.com for self-assessment and with reference to the above textbooks for background information. Already at the completion of this cookbook we came to realize, that many essential methods were not covered. The current volume, entitled "Machine Learning in Medicine - Cookbook Two" is complementary to the first and also intended for providing a more balanced view of the field and thus, as a must-read not only for physicians and students, but also for any one involved in the process and progress of health and health care. Similarly to Machine Learning in Medicine - Cookbook One, the current work will describe stepwise analyses of over twenty machine learning methods, that are, likewise, based on the three major machine learning methodologies: Cluster methodologies (Chaps. 1-3) Linear methodologies (Chaps. 4-11) Rules methodologies (Chaps. 12-20) In extras.springer.com the data files of the examples are given, as well as XML (Extended Mark up Language), SPS (Syntax) and ZIP (compressed) files for outcome predictions in future patients. In addition to condensed versions of the methods, fully described in the above three textbooks, an introduction is given to SPSS Modeler (SPSS' data mining workbench) in the Chaps. 15, 18, 19, while improved statistical methods like various automated analyses and Monte Carlo simulation models are in the Chaps. 1, 5, 7 and 8. We should emphasize that all of the methods described have been successfully applied in practice by the authors, both of them professors in applied statistics and machine learning at the European Community College of Pharmaceutical Medicine in Lyon France. We recommend the current work not only as a training companion to investigators and students, because of plenty of step by step analyses given, but also as a brief introductory text to jaded clinicians new to the methods. For the latter purpose, background and theoretical information have been replaced with the appropriate references to the above textbooks, while single sections addressing "general purposes", "main scientific questions" and "conclusions" are given in place. Finally, we will demonstrate that modern machine learning performs sometimes better than traditional statistics does. Machine learning may have little options for adjusting confounding and interaction, but you can add propensity scores and interaction variables to almost any machine learning method.