Download or read book Cancer Immunology and Immunotherapy written by Glenn Dranoff and published by Springer Science & Business Media. This book was released on 2011-04-11 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.
Download or read book Incorporated Society of Valuers and Auctioneers Directory of Members and Member Firms written by The Incorporated Society of Valuers and Auctioneers and published by Springer. This book was released on 2016-01-13 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the official publication for members and member firms of the Incorporated Society of Valuers and Auctioneers (ISVA). The directory contains the names and addresses of every member, and a complete list of practising firms and commercial concerns with member firms.
Download or read book Who s Who in Plastics Polymers written by James P. Harrington and published by CRC Press. This book was released on 2000-05-09 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first edition of a unique new plastics industry resource: Who's Who in Plastics & Polymers. It is the only biographical directory of its kind and includes contact, affiliation and background information on more than 3300 individuals who are active leaders in this industry and related organizations. The biographical directory is i
Download or read book World Radio TV Handbook 2005 written by Publishing Wrth and published by WRTH Publications. This book was released on 2004-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive source available on medium wave, shortwave, FM broadcast, and television broadcast information, this handbook continues to be the ultimate guide for the serious radio listener.
Download or read book Particulate Carbon written by Donald Siegla and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of the symposium, "Particulate Carbon: Formation During Combustion", held at the General Motors Research Laboratories on October 15 and 16, 1980, was to discuss fundamental aspects of soot formation and oxidation in combustion systems and to stimulate new research by extensive interactions among the participants. This book contains lhe papers and discussions of that symposium, the 26th in an annual series covering many different disciplines which are timely and of interest to both General Motors and the technical community at large. The subject of this symposium has considerable relevance for man in his effort to control and preserve his environment. Emission of particulate carbon into the atmos phere from combustion sources is of concern to scientists and laymen alike. The hope of reducing this emission clearly requires an understanding of its formation during the combustion process, itself an area of considerable long-term research interest. It is our hope that this symposium has served to summarize what is known so that what remains to be learned can be pursued with greater vigor.
Download or read book The Herd book written by and published by . This book was released on 1843 with total page 878 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book National Air Quality and Emissions Trends Report written by and published by . This book was released on 1994 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Flash Jim written by Kel Richards and published by HarperCollins. This book was released on 2021-05-01 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: The astonishing story of James Hardy Vaux, writer of Australia's first dictionary and first true-crime memoir If you wear 'togs', tell a 'yarn', call someone 'sly', or refuse to 'snitch' on a friend then you are talking like a convict. These words, and hundreds of others, once left colonial magistrates baffled and police confused. So comprehensible to us today, the flash language of criminals and convicts had marine officer Watkin Tench complaining about the need for an interpreter in the colonial court. Luckily, by 1811, that man was at hand. James Hardy Vaux - conman, pickpocket, absconder and thief, born into comfortable circumstances in England - was so drawn to a life of crime he was transported to Australia ... not once, but three times! Vaux's talents, glibness and audacity were extraordinary, and perceiving an opportunity to ingratiate himself with authorities during his second sentence, he set about writing a dictionary of the criminal slang of the colony, which was recognised for its uniqueness and taken back to England to be published. Kel Richards tells Vaux's story brilliantly, with the help of Vaux's own extraordinarily candid memoir of misdeeds - one of the first true-crime memoirs ever published. Kel's book combines two of his favourite subjects: the inventiveness, humour and origins of Australian English, and our history of fabulous, disreputable characters. With echoes of The Surgeon of Crowthorne as well as Oliver Twist, Flash Jim is a ripping read - especially for those who appreciate the power of words and the convict contribution to our idiom. PRAISE 'James Hardy Vaux was a con-man with a talent for words who wrote the first dictionary of Australian English. Kel Richards is a word-man with a talent for telling a stirring story about the con-man. In Flash Jim Kel Richards brings James Hardy Vaux to life as we haven't seen him before' - Emeritus Professor Roland Sussex, School of Languages and Comparative Cultural Studies, University of Queensland 'An engaging tale from a great student of our language about one of the conmen who gave Australia its character - and its distinctive slang' - Andrew Bolt, broadcaster and columnist 'One of the strongest bonds binding the people of Australia together is the Australian language. We speak a dialect of English richer and more colourful than most. When we call someone a "hoon" or invite a friend to a "barbie" we know immediately what we're talking about - but we have to translate for overseas visitors. This powerful cultural bond was, as Kel explains, built on four foundations. And the most colourful of those four was convict slang. The role that it played, and still plays, in the Australian language, and the story of the man who first recorded it is - as we used to say - a "ripping yarn". It makes a page-turning story' - Alan Jones, broadcaster and columnist 'There's never been a more important time to truly understand our Australian history and this book is a great introduction to the richness of our language and a wonderful window onto the real life of colonial Australia from my favourite wordsmith, Kel Richards' - Peta Credlin, broadcaster and columnist
Download or read book Manufacturing written by Beno Benhabib and published by CRC Press. This book was released on 2003-07-03 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: From concept development to final production, this comprehensive text thoroughly examines the design, prototyping, and fabrication of engineering products and emphasizes modern developments in system modeling, analysis, and automatic control. This reference details various management strategies, design methodologies, traditional production techniqu
Download or read book Particulate Carbon written by George T. Wolff and published by Springer. This book was released on 2012-04-06 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the papers and discussions from the symposium, "PARTICU LATE CARBON: Atmospheric Life Cycle," held at the General Motors Research Laboratories on October 13-14, 1980. This symposium, which focused on atmospheric particulate elemental carbon, or soot, was the twenty-fifth in this series sponsored by the General Motors Research Laboratories. The present symposium volume contains discussions of the following aspects of particulate elemental carbon (EC): the atmos pheric life cycle of EC including sources, sinks, and transport processes, the role of EC in atmospheric chemistry and optics, the possible role of EC in altering climate, and measurement techniques as well as ambient concentrations in urban, rural, and remote areas. Previous symposia have covered a wide range of scientific and engineering subjects. Topics are selected because they are new or represent rapidly changing fields and are of significant technical importance. It is ironic that the study of particulate elemental carbon or soot should meet the above criteria for selection because soot, especially from coal and wood combustion, has been a recognized air pollutant for centuries. However, since the 1950s, when intense efforts to study air pollution were initiated, to until a few years ago, the role of elemental carbon in the atmosphere was largely ignored. The major reason for this was the lack of a suitable measurement technique.
Download or read book Group B Coxsackieviruses written by Steven Tracy and published by Springer. This book was released on 2008-02-18 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: At last – a volume that virologists have been waiting for: a fully updated new edition of a major study in a key subject area. The first edition of this work, published in 1997, described the molecular biology of coxsackie B viruses, as well as clinical, epidemiological, and immunological aspects of group B coxsackievirus disease. This brand new edition covers all the research accomplishments of the last ten years in this vital area of medicine, including immunopathology.
Download or read book Health Effects of Exposure to Diesel Exhaust written by National Research Council (U.S.). Diesel Impacts Study Committee. Health Effects Panel and published by National Academies. This book was released on 1981 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Licence Renewals Commercial and Public Broadcasting Stations 2AD 2LM 2NZ 2RE 2TM 2ARM FM and 2NCR FM New South Wales written by Australian Broadcasting Tribunal and published by . This book was released on 1985 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: