Download or read book Handbook of Pharmaceutical Manufacturing Formulations written by Sarfaraz K. Niazi and published by CRC Press. This book was released on 2004-04-27 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third volume in the six-volume Handbook of Pharmaceutical Manufacturing Formulations, this book covers liquid drugs, which include formulations of non-sterile drugs administered by any route in the form of solutions (monomeric and multimeric), suspensions (powder and liquid), drops, extracts, elixirs, tinctures, paints, sprays, colloidons, emul

Download or read book Pharmaceutical Manufacturing Handbook written by Shayne Cox Gad and published by John Wiley & Sons. This book was released on 2008-03-11 with total page 1386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook features contributions from a team of expert authors representing the many disciplines within science, engineering, and technology that are involved in pharmaceutical manufacturing. They provide the information and tools you need to design, implement, operate, and troubleshoot a pharmaceutical manufacturing system. The editor, with more than thirty years' experience working with pharmaceutical and biotechnology companies, carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear.

Download or read book 3D Printing written by Michael A. Repka and published by Springer Nature. This book was released on 2024-01-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: This inclusive text describes 3D Printing for pharmaceutical applications, including emerging 3D technologies. The book focuses on the functionality of the materials/biomaterials used for the preparation of dosage forms and devices, fundamentals for preparing these systems and novel applications using these additive manufacturing techniques. Also, the text includes clinical relevance and regulatory considerations for the future of personalized medicine. Authored by experts with a broad range of experience, extensive insight into the science of 3D printing technology used to produce these systems is provided. Highlighting viewpoints from the academic, polymer excipient, equipment, product development and regulatory communities, this comprehensive text compiles input from industry thought leaders to illustrate strategies and technologies for applying techniques of additive manufacturing for drug product and device development while also providing insight into the path forward for the technology in years to come.

Download or read book Handbook of Pharmaceutical Manufacturing Formulations Third Edition written by Sarfaraz K. Niazi and published by CRC Press. This book was released on 2019-12-06 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Pharmaceutical Manufacturing Formulations, Third Edition: Volume Five, Over-the-Counter Products is an authoritative and practical guide to the art and science of formulating drugs for commercial manufacturing. With thoroughly revised and expanded content, this fifth volume of a six-volume set, compiles data from FDA and EMA new drug applications, patents and patent applications, and other sources of generic and proprietary formulations including author’s own experience, to cover the broad spectrum of cGMP formulations and issues in using these formulations in a commercial setting. A must-have collection for pharmaceutical manufacturers, educational institutions, and regulatory authorities, this is an excellent platform for drug companies to benchmark their products and for generic companies to formulate drugs coming off patent. Features: Largest source of authoritative and practical formulations, cGMP compliance guidance and self-audit suggestions Differs from other publications on formulation science in that it focuses on readily scalable commercial formulations that can be adopted for cGMP manufacturing Tackles common difficulties in formulating drugs and presents details on stability testing, bioequivalence testing, and full compliance with drug product safety elements Written by a well-recognized authority on drug and dosage form development including biological drugs and alternative medicines

Download or read book Melt Extrusion written by Michael A. Repka and published by Springer Science & Business Media. This book was released on 2013-10-11 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides readers with the basic principles and fundamentals of extrusion technology and a detailed description of the practical applications of a variety of extrusion processes, including various pharma grade extruders. In addition, the downstream production of films, pellets and tablets, for example, for oral and other delivery routes, are presented and discussed utilizing melt extrusion. This book is the first of its kind that discusses extensively the well-developed science of extrusion technology as applied to pharmaceutical drug product development and manufacturing. By covering a wide range of relevant topics, the text brings together all technical information necessary to develop and market pharmaceutical dosage forms that meet current quality and regulatory requirements. As extrusion technology continues to be refined further, usage of extruder systems and the array of applications will continue to expand, but the core technologies will remain the same.

Download or read book Bioadhesive Drug Delivery Systems written by Vincent M. Lenaerts and published by CRC Press. This book was released on 1989-11-30 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensively written text covers, in-depth, all aspects of bioadhesive systems. Bioadhesive systems are presently playing a major role in the field because of their ability to maintain a dosage form at a precise body-site for a prolonged period of time over which the active principle is progressively released. Included in this book are descriptions of the different mucosae in healthy and pathological situations, a theoretical approach of polymers-mucin interactions, and a comparative description of the methods used to evaluate bioadhesion. Up-to-date reviews of pharmaceutical applications are also given - subdivided according to the route of administration and type of system. It also contains a chapter devoted to the fundamentals of bioadhesion. This reference is an indispensable guide for researchers in the pharmaceutical field as well as academic researchers.

Download or read book Gardner s Commercially Important Chemicals written by G. W. A. Milne and published by John Wiley & Sons. This book was released on 2005-09-02 with total page 1205 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exhaustive resource for the industrial chemical community Through eleven editions, Gardner's Chemical Synonyms and Trade Names has become the best-known and most widely used source of information on chemicals in commerce. This companion book reflects the continuing research underlying Gardner's and presents a major expansion of the information provided for individual chemical compounds. Gardner's Commercially Important Chemicals: Synonyms, Trade Names, and Properties: * Contains 4,174 chemical entries and information such as structure, molecular formula, and chemical name * Includes synonyms for each chemical, including other identifiers, chemical names, trade names, and trivial names, in English and other languages * Provides chemical properties of the compounds, information concerning known uses of the chemical and biological data-in particular, acute toxicity in various species, where available * Lists the companies that manufacture or supply the listed chemicals * Describes bulk inorganic chemicals, major pesticides (herbicides, insecticides, antifungal agents, etc.), and many dyestuffs, surfactants, and metals, along with the most commonly used drugs * Contains indexes by chemical name and synonym, Chemical Abstracts Service (CAS) Registry Numbers, and EINECS (European Inventory of Existing Commercial Substances) numbers One useful feature of this database is the inclusion of physical properties and use data for pure chemicals. Properties that have been provided, when available, include: the melting point, boiling point, density or specific gravity, optical rotation, ultraviolet absorption, solubility, and acute toxicity. The major uses of most of the chemicals are indicated and, where appropriate, regulatory information is also provided.

Download or read book Polyvinylpyrrolidone Excipients for Pharmaceuticals written by Volker Bühler and published by Springer Science & Business Media. This book was released on 2005 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book describes the properties, analytical methods and the applications of different polyvinylpyrrolidone excipients (povidone, crospovidone, copovidone etc.) for use in pharmaceutical preparations. This group of excipients is one of the most important excipients used in modern technology to produce drugs. The book is intended for all persons working in the research, development and quality control of drugs. It gives a survey of all applications in solid, liquid and semisolid dosage forms including many drug formulation examples and more than 600 references to the literature.

Download or read book Fundamentals and Applications of Controlled Release Drug Delivery written by Juergen Siepmann and published by Springer Science & Business Media. This book was released on 2011-12-14 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pitched at a level comprehensible to those new to the field, this authoritative text covers the scientific and technological fundamentals of drug delivery as well as clinical applications and the developmental potential in controlled release drug delivery.

Download or read book Handbook of Fillers Extenders and Diluents written by Michael Ash and published by Synapse Info Resources. This book was released on 2007 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Hot Melt Extrusion written by Dennis Douroumis and published by John Wiley & Sons. This book was released on 2012-04-24 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hot-melt extrusion (HME) - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets. Hot-Melt Extrusion: Pharmaceutical Applications covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME products. Finally, the book includes some recent and novel HME applications, scale -up considerations and regulatory issues. Topics covered include: principles and die design of single screw extrusion twin screw extrusion techniques and practices in the laboratory and on production scale HME developments for the pharmaceutical industry solubility parameters for prediction of drug/polymer miscibility in HME formulations the influence of plasticizers in HME applications of polymethacrylate polymers in HME HME of ethylcellulose, hypromellose, and polyethylene oxide bioadhesion properties of polymeric films produced by HME taste masking using HME clinical studies, bioavailability and pharmacokinetics of HME products injection moulding and HME processing for pharmaceutical materials laminar dispersive & distributive mixing with dissolution and applications to HME technological considerations related to scale-up of HME processes devices and implant systems by HME an FDA perspective on HME product and process understanding improved process understanding and control of an HME process with near-infrared spectroscopy Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science. This is the first book from our brand new series Advances in Pharmaceutical Technology. Find out more about the series here.

Download or read book Handbook of Pyrrolidone and Caprolactam Based Materials 6 Volume Set written by Osama M. Musa and published by John Wiley & Sons. This book was released on 2021-07-06 with total page 2665 pages. Available in PDF, EPUB and Kindle. Book excerpt: HANDBOOK OF PYRROLIDONE AND CAPROLACTAM BASED MATERIALS Brings together, for the first time, a comprehensive review of all aspects of pyrrolidone- and caprolactam-based materials This comprehensive, six-volume set describes the broad technical universe of γ- and ε- lactams, reviewing in-depth the chemistry of the small lactam-based molecules, uncovering their unique properties and showing how they have enabled a myriad of commercially important applications. From synthesis, through production and into applications, this extensive work targets significant and recent trends in γ- and ε-lactam science and technology and addresses all key aspects of pyrrolidone- and caprolactam-based materials to produce a definitive overview of the field. Handbook of Pyrrolidone and Caprolactam Based Materials provides a detailed and modern portrait of the impact of pyrrolidone- and caprolactam-based materials on the world, as well as potential future possibilities. Volume One presents the chemistry of small lactam-based molecules and uncovers their unique properties. Volume Two covers polymeric materials, including polyvinyl pyrrolidone and polyvinyl caprolactam, and reviews homopolymerization, copolymerization, controlled radical polymermization and acrylate based pyrrolidone polymerizations. Volume Three examines the physical chemistry and molecular interactions of pyrrolidone and caprolactam based materials. Volume Four expands upon the characterization theme from the third volume, and includes detailed discussions of nuclear magnetic resonance (NMR) and Fourier transform-infrared (FT-IR) spectroscopy, thermal and mechanical properties, and imaging techniques. Volume Five explores pharmaceutical applications in both ingredients and materials, as well as the antimicrobial properties and applications of pyrrolidone and caprolactam-based materials, and their toxicology. Volume Six covers personal and home care, skin care, transdermal applications and wound care, oral care, adhesion related applications and digital applications such as inkjet technology. Handbook of Pyrrolidone and Caprolactam Based Materials will appeal to industrial scientists and engineers interested in polymer development and manufacturing. It will also benefit academic researchers working in the fields of chemistry, materials science, and chemical and process engineering.

Download or read book Novel Approaches for the Delivery of Anti HIV Drugs written by José das Neves and published by MDPI. This book was released on 2020-05-20 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIV/AIDS continues to be one of the most challenging individual and public health concerns of the present day. According to the UNAIDS, nearly 38 million individuals were living with the infection by the end of 2018, while 1.7 million new cases occurred during that same year. In spite of the numerous advances in the development and delivery of antiretroviral agents, both for treatment and prevention, several challenges remain. This book includes original research and review articles on innovative strategies and approaches for the formulation and delivery of anti-HIV drugs, including genetic material and other biopharmaceuticals. Different local and systemic delivery strategies are addressed based on different technologies intended for oral, transdermal, subcutaneous, vaginal, or rectal administration. Authored by eminent scientists in academia and nonprofit organizations involved in the development of antiretroviral drug products, this collection provides useful information for all those involved in HIV/AIDS treatment and prevention.

Download or read book Amorphous Drugs written by Marzena Rams-Baron and published by Springer. This book was released on 2018-02-09 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products.

Download or read book 3D Industrial Printing with Polymers written by Johannes Karl Fink and published by John Wiley & Sons. This book was released on 2018-11-30 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: 3D industrial printing has become mainstream in manufacturing. This unique book is the first to focus on polymers as the printing material. The scientific literature with respect to 3D printing is collated in this monograph. The book opens with a chapter on foundational issues such and presents a broad overview of 3D printing procedures and the materials used therein. In particular, the methods of 3d printing are discussed and the polymers and composites used for 3d printing are detailed. The book details the main fields of applications areas which include electric and magnetic uses, medical applications, and pharmaceutical applications. Electric and magnetic uses include electronic materials, actuators, piezoelectric materials, antennas, batteries and fuel cells. Medical applications are organ manufacturing, bone repair materials, drug-eluting coronary stents, and dental applications. The pharmaceutical applications are composite tablets, transdermal drug delivery, and patient-specific liquid capsules. A special chapter deals with the growing aircraft and automotive uses for 3D printing, such as with manufacturing of aircraft parts and aircraft cabins. In the field of cars, 3D printing is gaining importance for automotive parts (brake components, drives), for the fabrication of automotive repair systems, and even 3D printed vehicles.

Download or read book PVP Polyvinylpyrrolidone written by General Aniline & Film Corporation. Development Dept and published by . This book was released on 1951 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Rheology Modifiers Handbook written by David D. Braun and published by Elsevier. This book was released on 2013-10-22 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first single-volume handbook with the information a researcher needs to select the best rheology modifiers for his/her project. Information on 20 different types of rheology modifiers manufactured by 26 companies worldwide is described. These range from Acrylic Polymers to Xanthan Gum. This handbook was written because, in the authors' experience, the selection of a rheology modifier for specific applications is an arduous task. It requires researching the technical literature of numerous suppliers, contacting them for current information and recommendations, and paring the list of candidates from hundreds to a few dozen. This book will enable readers to easily identify the best candidates for an application with a minimum investment of time.The book is divided into four sections. Part I reviews rheology fundamentals. Part II presents details on the products available from the 26 represented companies. Part III focuses on the selection of suitable rheology modifier candidates. Part IV is a formulary containing the contributions of the suppliers.