Download or read book Kidney Organogenesis written by Seppo Vainio and published by Humana Press. This book was released on 2019-02-13 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book details protocols on classical methods and very modern ex vivo mammalian developmental kidney model systems. Chapters focus on generation of mosaic embryonic kidneys, culture of the kidney tissues ex vivo, embryonic kidney progenitor cell, 3Dkidney model cell line based cultures, programming the kidney cell fates in human pluripotent cells, protocols to target the functional players in kidney ontogenesis, 4D and 3D ex vivo imaging, drosphila, and computational approaches to kidney ontogenesis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Kidney Organogenesis: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Download or read book Organogenesis of the Kidney written by Lauri Saxen and published by Cambridge University Press. This book was released on 1987-04-16 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although this description of a model system for cell differentation and organogenesis emphasizes the mammalian kidney, detailed coverage is also given to the development of the transient excretory organs.
Download or read book The Kidney written by Peter D. Vize and published by Elsevier. This book was released on 2003-03-14 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organogenesis of the kidney has been intensely studied for over a century. In recent years advances in molecular techniques have not only made great inroads into exploring the genetic regulation of this complex process but also began to unravel the molecular basis of many forms of congenital kidney disease. This book is a comprehensive study on these findings and the only book available with such in depth coverage of the kidney. - Hundreds of color figures depicting key events in all aspects of kidney development - Full coverage of the genetic and cellular basis of kidney development - Analysis of the genetic basis of the major congenital kidney diseases
Download or read book Kidney Development Disease Repair and Regeneration written by Melissa Helen Little and published by Academic Press. This book was released on 2015-08-06 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney Development, Disease, Repair and Regeneration focuses on the molecular and cellular basis of kidney development, exploring the origins of kidney lineages, the development of kidney tissue subcompartments, as well as the genetic and environmental regulation of kidney development. Special coverage is given to kidney stem cells and possible steps towards kidney repair and regeneration. Emphasis is placed on the fetal origins of postnatal renal disease and our current understanding of the molecular basis of damage and repair. Biomedical researchers across experimental nephrology and developmental biology will find this a key reference for learning how the underlying developmental mechanisms of the kidney will lead to greater advances in regenerative medicine within nephrology. - Offers researchers a single comprehensive resource written by leaders from both the developmental biology and the experimental nephrology communities - Focuses on understanding the molecular basis of organogenesis in the kidney as well as how this can be affected both genetically and environmentally - Explains the underlying developmental mechanisms which influence the kidney's inherent repair capacity - Demonstrates how a deeper understanding of mechanisms will lead to greater advances in regenerative medicine
Download or read book Gynecologic and Urologic Pathology written by Maria Rosaria Raspollini and published by Cambridge University Press. This book was released on 2019-02-21 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the similarities and differences in the pathology of the genital and urinary tracts in males and females.
Download or read book Oxford Textbook of Clinical Nephrology written by Neil N. Turner and published by Oxford University Press. This book was released on 2015-10-29 with total page 3045 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts. The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field. This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management. Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence. This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.
Download or read book Normal and Abnormal Development of the Kidney written by Edith Louise Potter and published by . This book was released on 1972 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Regenerative Medicine in Urology written by Bup Wan Kim and published by Springer. This book was released on 2017-09-14 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multidisciplinary book provides up-to-date information on clinical approaches that combine stem or progenitor cells, biomaterials and scaffolds, growth factors, and other bioactive agents in order to offer improved treatment of urologic disorders including lower urinary tract dysfunction, urinary incontinence, neurogenic bladder, and erectile dysfunction. In providing clinicians and researchers with a broad perspective on the development of regenerative medicine technologies, it will assist in the dissemination of both regenerative medicine principles and a variety of exciting therapeutic options. After an opening section addressing current developments and future perspectives in tissue engineering and regenerative medicine, fundamentals such as cell technologies, biomaterials, bioreactors, bioprinting, and decellularization are covered in detail. The remainder of the book is devoted to the description and evaluation of a range of cell and tissue applications, with individual chapters focusing on the kidney, bladder, urethra, urethral sphincter, and penis and testis.
Download or read book The Testicular Descent in Human written by K.J. Barteczko and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: The testicular descent (descensus testis) is described in a complete series of human material from stage 14 CC to the adult state by using own phases. Central points of interest in this work are answers to questions which have been discussed controversially by generations of scientists and which are wrong or inadequately documented in most textbooks of embryology: Does an inner gonadal descent exist? What about origin, role and fate of gubernaculum H., processus vaginalis peritonei and gonadal ligaments? How do the annexes of testis come into their final position? The results are based on serial sections, scanning electron microscopy, three-dimensional reconstructions, microdissection and immunohistochemistry.
Download or read book Textbook of Clinical Embryology written by Kevin Coward and published by Cambridge University Press. This book was released on 2013-10-31 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.
Download or read book Pediatric Nephrology written by Ellis D. Avner and published by Springer Science & Business Media. This book was released on 2009-08-20 with total page 2059 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is an extensive update of Pediatric Nephrology, which has become the standard reference text in the field. It is global in perspective and reflects the international group of editors, who are well-recognized experts in pediatric nephrology. Within this text, the development of kidney structure and function is followed by detailed and comprehensive chapters on all childhood kidney diseases.
Download or read book Regenerative Nephrology written by Michael S. Goligorsky and published by Academic Press. This book was released on 2010-11-26 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progression of chronic diseases in general and chronic kidney disease in particular has been traditionally viewed in the light of various contributors to development of glomerulosclerosis and tubulointerstitial scarring culminating in renal fibrosis. Indeed, this dogma prevailed for decades underscoring experimental attempts to halt fibrotic processes. Breakthrough investigations of the past few years on stem/progenitor cell involvement in organ regeneration caused a conceptual shift in tackling the mechanisms of nephrosclerosis. It has become clear that the rate of progression of chronic kidney disease is the net sum of the opposing trends: degenerative fibrotic processes and regenerative repair mechanisms. The latter part of this equation has been by and large ignored for years and only recently attracted investigative attention. This book revisits the problem of kidney disease by focusing on regenerative mechanisms in renal repair and on the ways these regenerative processes can become subverted by an intrinsic disease process eventuating in its progression. Cutting-edge investigations are summarized by the most experienced international team of experts. - Presents a comprehensive, translational source for all aspects of renal stem cells, tissue regeneration, and stem cell therapies for renal diseases in one reference work. This will ultimately result in time savings for academic, medical and pharma researchers - Experts in the renal stem cell system in kidney repair and regeneration take readers from the bench research to new therapeutic approaches, providing a common language for nephrology researchers, fellows and other stem cell researchers. This enables the discussion of development of stem cells and their use in the repair and regeneration of the kidney
Download or read book Atlas of Medical Renal Pathology written by Stephen M. Bonsib and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: The kidney is an organ with complex organogenesis susceptible to numerous misadventures in development and is exposed to a diverse array of insults of hematogenous and lower urinary tract origin. This Atlas of Medical Renal Pathology provides an overview of the development, macroscopic and microscopic features of the normal kidney. This is followed by a comprehensive survey of developmental and cystic kidney diseases, vascular diseases and tubulointerstitial diseases. An emphasis is placed on gross diagnostic findings with detailed histological correlates. In addition, the histological, immunofluorescent, immunohistochemical and ultrastructural features of the major glomerular diseases and renal transplantation pathology are presented. This compendium of non-neoplastic kidney diseases illustrates the vast majority diseases you are likely to encounter in surgical and autopsy pathology.
Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.
Download or read book Kidney Development and Disease written by Rachel K. Miller and published by Springer. This book was released on 2017-04-13 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney Development and Disease brings together established and young investigators who are leading authorities in nephrology to describe recent advances in three primary areas of research. The first section describes the use of animal models as powerful tools for the discovery of numerous molecular mechanisms regulating kidney development. The second section focuses on nephric cell renewal and differentiation, which lead to diverse cell fates within the developing kidney, and discusses diseases resulting from the aberrant regulation of the balance between cell fate decisions. The final section concentrates on morphogenesis of the developing kidney and its maintenance after formation as well as the diseases resulting from failures in these processes. Kidney form and function have been extensively studied for centuries, leading to discoveries related to their development and disease. Recent scientific advances in molecular and imaging techniques have broadened our understanding of nephron development and maintenance as well as the diseases related to these processes.
Download or read book Organ Development written by and published by Academic Press. This book was released on 2019-02-21 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organ Development, Volume 132, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapter written by an international board of authors. This volume highlights cogent reviews of the development, maintenance and regeneration/repair of several organ systems, from eye to kidney, to the musculoskeletal system. Many reviews highlight new techniques or technologies that are currently pushing the field. The role of both embryonic and adult stem cells are highlighted and senior authors are all women scientists. - Provides the authority and expertise of leading contributors from an international board of author - Presents the latest release in this series - Updated release includes the latest information on organ development
Download or read book Regenerative Medicine Applications in Organ Transplantation written by Giuseppe Orlando and published by Academic Press. This book was released on 2013-10-11 with total page 1050 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results. - Bridges the gap between regenerative medicine and solid organ transplantation and highlights reasons for collaboration - Explains the importance and future potential of regenerative medicine to the transplant community - Illustrates to regenerative medicine investigators the needs of the transplant discipline to drive and guide investigations in the most promising directions
