Download or read book Joint Imaging Applications in General Neurodegenerative Disease written by Yongxia Zhou and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple advanced neuroimaging applications in various neurodegenerative diseases including Parkinson's disease (PD), frontotemporal dementia (FTD), vascular dementia (VaD) and autism spectrum disorder (ASD) are covered in this book. Relatively novel techniques such as integrated PET/MRI and independent component analysis (ICA)-based dual regression (DR) methods were developed to capture multi-level molecular/functional and structural/microstructural as well as high-order inter-network coordination abnormalities. For instance, both PET dopamine transporter and striatal binding ratio reductions in the caudate and putamen were found in PD, consistent with the diffusion tensor imaging (DTI) fractional anisotropy (FA) reduction and fMRI voxel-mirrored homotopic correlation (VMHC) in the substantia nigra (swallow tail sign signature of PD). Furthermore, dopamine storage and pathway labeled with the vesicular monoamine transporter tracer identified decreased densities in the bilateral mesial temporal cortex, caudate, orbitofrontal cortex, left frontal and occipital cortices, consistent with the morphological atrophy, functional connectivity and conductivity deficits in PD. Similarly in FTD patients, the advanced MRI methods such as ICA-DR, VMHC, voxel-based morphometry (VBM) as well as PET tracer for amyloid accumulation and FDG glucose uptake identified typical brain atrophy, structural dis-connectivity, glucose hypometabolism, higher neuropathological burden, lower interhemispheric correlation as well as disrupted intra- and inter-network modulation in the orbitofrontal and anterior temporal cortices together with insular and frontoparietal networks, with the cerebellum and dorsolateral attentional network as typical compensations.Functional and structural abnormalities had further been elucidated in the VaD dependent participants and autistic children. For instance, both lower FA and VMHC, brain atrophy and functional connectivity deficits, demyelination, axonal degeneration and white matter integrity damage in several white matter tracts were present in the dependent compared to independent participants in VaD data cohort. Increased neuronal activity with higher global fractional amplitude of low frequency fluctuation (fALFF) in the conventional and slow-wave sub-band was confirmed with less efficiency of systematic integration in VaD dependent group. Moreover, in ASD compared to controls, regional gray matter volume and cortical thickness in all four brain lobes increased, whereas white matter volume were decreased in addition to the lower temporal, visual and superior frontal but higher inferior and dorsolateral prefrontal cortical functional connectivities exhibited in ASD. The differences in each type of disease could also be revealed with the same imaging method based on either unique region or distinct brain circuit inter-connection, using VMHC, ICA-DR, DTI, VBM, fALFF and graph-theory based small-worldness analysis.In this book, we have developed and generalized conventional and advanced imaging methodologies to several common neurodegenerative diseases. For instance, we have identified the unique imaging signature for each disease type and the underlying neuropathological mechanism connections with conductivity, structural and microstructural connectivity, intra- and inter-network correlation, systematic integration and efficiency analyses. Our objective, comprehensive and confirmative results indicated great potential in utilizing these quantifications for accurate disease classification and staging. With solid imaging evidence, thorough analysis and generalized applications, this book should capture the interests of readers in the broad fields of brain science, disease diagnosis and effective treatment.

Download or read book Molecular Imaging of Neurodegenerative Disorders written by Donna J. Cross and published by Springer Nature. This book was released on 2023-09-26 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review of the role of molecular imaging in neurodegenerative diseases. A growing field, molecular imaging of neurodegeneration is becoming increasingly relevant with an aging population, and this book serves to provide both an introduction to the concept and background of neurodegeneration and an update on the most recent imaging advances. Throughout, chapters will review current applications of neuroimaging in neurodegenerative disorders, like dementia and movement disorders, and increase knowledge of quantification and semi-quantification methods for neuroimaging. Imaging methods such as PET/CT and PET/MR are covered, as well as more advanced technologies like artificial intelligence algorithms and novel radiotracers. Chapters are also intended to improve competency in reporting and interpretation skills with structured information on current practice. The book concludes with a collection of up to date practice cases for the interpretation of neurodegeneration in nuclear medicine imaging. This is an ideal guide for nuclear medicine physicians, neuroradiologists, neurologists, residents, trainees, and related medical professionals caring for patients with neurodegeneration.

Download or read book Imaging in Neurodegenerative Disorders written by Luca Saba and published by OUP Oxford. This book was released on 2015-01-08 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosing neurodegenerative diseases can prove particularly intimidating to clinicians, because many times the diagnosis cannot be critically "confirmed" by a simple test. New imaging modalities have advanced to the point of high resolution, morphological, metabolic and functional analysis. Computed tomography, magnetic resonance, nuclear medicine and molecular imaging have recently emerged as outstanding non-invasive techniques for the study of the neurodegenerative disorders. Imaging in Neurodegenerative Disorders covers all the imaging techniques and new exciting methods like new tracers, biomarker, metabolomic and gene-array profiling, potential for applying such techniques clinically, and offers present and future applications as applied to the neurodegenerative disorders with the most world renowned scientists in these fields. This book is an invaluable resource for researchers, clinicians, and trainees in neuroscience, neurology, psychiatry, and radiology.

Download or read book Imaging of Neurodegenerative Disorders written by Sangam G. Kanekar and published by Thieme. This book was released on 2015-11-05 with total page 1176 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive reference on imaging and diagnosis of neurodegenerative diseases FIVE STARS from Doody's Star Ratings™ Imaging of Neurodegenerative Disorders is a comprehensive, up-to-date reference covering the latest techniques used in neuroimaging as well as the basic structural imaging that facilitates diagnosis of various neurodegenerative disorders. All advanced imaging modalities, including MR spectroscopy, DTI, MRI, and PET scans, are discussed in detail, enabling readers to gain a solid understanding of how to use them to diagnose neurodegenerative diseases. Key Features: Each chapter covers the clinical features, pathology, and imaging of a specific disease/disorder Sections on cerebellar degeneration and dysfunction, motor neuron disorders, post-traumatic cognitive disorders, dementia with extrapyramidal syndromes, and deep brain stimulation A final section discusses the distinctions between preventable, potentially reversible, and irreversible dementia This book provides radiologists and all who care for patients suffering from neurodegenerative diseases with an invaluable reference that will be part of their medical library for many years to come.

Download or read book Integrative Imaging in Neuroplasticity Wisdom and Neuropsychiatry written by Yongxia Zhou and published by Ethics International Press. This book was released on 2023-11-25 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book demonstrates the beneficial effects in brain circuits involving memory and attention, reward and social values, decision making and coordination, creativity and persistence of the skills and expertise of continuing education and exposure to the Arts; including chess practice, music/counting, college education and watching movies. These activities were reviewed and investigated using full-spectrum, advanced quantitative imaging techniques. The book highlights extensive applications for this research in common diseases, together with cutting-edge and full-spectrum static and dynamic, functional and structural, regional and inter-network, imaging and phenotypic scales. It will capture the interest of researchers in the areas of neurodevelopmental, neuroplasticity and neuropsychiatric imaging and correlation, as well as disease diagnosis and treatment, and could help convey the methodological innovation and neuroscientific applications of important educational, health and arts/science-related topics.

Download or read book Musculoskeletal Diseases 2021 2024 written by Juerg Hodler and published by Springer Nature. This book was released on 2021 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on imaging of the musculoskeletal diseases. Over the last few years, there have been considerable advances in this area, driven by clinical as well as technological developments. The authors are all internationally renowned experts in their field. They are also excellent teachers, and provide didactically outstanding chapters. The book is disease-oriented and covers all relevant imaging modalities, with particular emphasis on magnetic resonance imaging. Important aspects of pediatric imaging are also included. IDKD books are completely re-written every four years. As a result, they offer a comprehensive review of the state of the art in imaging. The book is clearly structured with learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers easily navigate through the text. As an IDKD book, it is particularly valuable for general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic knowledge, and for clinicians interested in imaging as it relates to their specialty.

Download or read book Innovative Imaging Techniques in Preclinical Models of Neurodegenerative Diseases written by Rodolfo Gabriel Gatto and published by Frontiers Media SA. This book was released on 2022-02-10 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Atypical Parkinsonian Disorders written by Irene Litvan and published by Springer Science & Business Media. This book was released on 2007-10-27 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of what is known not only about the cause and treatment of atypical parksonian disorders, but also the issues that clinicians, researchers, patients, and caregivers face in dealing with them. The authors cover the basic science (history, epidemiology, genetics, pathology, nosology, computer modeling, and animal models), detailed clinical and laboratory assessments, and available diagnostic tools, including neuropsychiatric, neurologic, neuropsychologic, speech, electrophysiologic, and imaging evaluations. Current and future therapeutic approaches are also detailed, along with extensive discussions about future research directions.

Download or read book Selected Health Conditions and Likelihood of Improvement with Treatment written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-07-12 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Social Security Administration (SSA) administers two programs that provide disability benefits: the Social Security Disability Insurance (SSDI) program and the Supplemental Security Income (SSI) program. SSDI provides disability benefits to people (under the full retirement age) who are no longer able to work because of a disabling medical condition. SSI provides income assistance for disabled, blind, and aged people who have limited income and resources regardless of their prior participation in the labor force. Both programs share a common disability determination process administered by SSA and state agencies as well as a common definition of disability for adults: "the inability to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period of not less than 12 months." Disabled workers might receive either SSDI benefits or SSI payments, or both, depending on their recent work history and current income and assets. Disabled workers might also receive benefits from other public programs such as workers' compensation, which insures against work-related illness or injuries occurring on the job, but those other programs have their own definitions and eligibility criteria. Selected Health Conditions and Likelihood of Improvement with Treatment identifies and defines the professionally accepted, standard measurements of outcomes improvement for medical conditions. This report also identifies specific, long-lasting medical conditions for adults in the categories of mental health disorders, cancers, and musculoskeletal disorders. Specifically, these conditions are disabling for a length of time, but typically don't result in permanently disabling limitations; are responsive to treatment; and after a specific length of time of treatment, improve to the point at which the conditions are no longer disabling.

Download or read book Production Quality Control and Clinical Applications of Radiosynovectomy Agents written by IAEA and published by International Atomic Energy Agency. This book was released on 2021-06-25 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic radiopharmaceuticals play a major role in today's nuclear medicine with a positive impact on the diagnosis and treatment of diseases. One area of application is radiation synovectomy (RSV). Previously, RSV agents were often simple colloids. More recently, matrixes labelled with short/medium range beta emitters have been developed. However, the lack of generic and peer-reviewed production, quality control as well as clinical application guidelines and recommendations, are a major concern for their application in patients. This publication presents recommendations and suggestions for production, quality control and quality assurance procedures for Member State laboratories in charge of radiopharmaceutical production, with a focus on the latest RSV agents. It also proposes standard operating procedures for RSV application in patients. The publication aims to assist both newcomers and those currently working in the field in establishing comparable levels of control.

Download or read book Clinical Application of Medical Imaging for Functional Evaluation in Orthopaedics written by Tsung-Yuan Tsai and published by Frontiers Media SA. This book was released on 2023-10-11 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Imaging in Neurodegenerative Disorders written by Luca Saba and published by Oxford University Press, USA. This book was released on 2015 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text summarizes the latest developments in imaging techniques and other new diagnostic methods as applied to the neurodegenerative disorders.

Download or read book Biomarkers from Multi tracer and Multi modal Neuroimaging in Age related Neurodegenerative Diseases written by Ping Wu and published by Frontiers Media SA. This book was released on 2022-09-12 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Essential Bioimaging Methods written by P. Michael Conn and published by Academic Press. This book was released on 2009-10-05 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Need a tested, reliable method that works? Put Essential Bioimaging Methods to work for you. Editor Michael Conn has hand-picked the most robust methods from his previously-published volumes in the Methods in Enzymology series. Many of these methods have been briefly updated by the authors that created them and use them in their research, and this book further refines and organizes existing content and focuses on methods that work, including MRI, fMRI, PET, Microscopic optical imaging and other. Part of the Reliable Lab Solution series, this volume provides clear advice and explicit protocols, providing updates to classic, tried-and-true methods and an essential addition to the bookshelf or workbench of any researcher in the field. * Highlights usefulness of techniques in basic research detailing MRI imaging of small animals, fMRI of Macaque monkeys, and baboon model of reperfused stroke * Built from volumes in the flagship brand, Methods in Enzymology * Provides tricks, tips and different approaches

Download or read book Musculoskeletal Imaging E Book written by Thomas Pope and published by Elsevier Health Sciences. This book was released on 2014-11-03 with total page 2884 pages. Available in PDF, EPUB and Kindle. Book excerpt: In its fully revised and updated second edition, Musculoskeletal Imaging covers every aspect of musculoskeletal radiology. This medical reference book incorporates the latest diagnostic modalities and interventional techniques, as well as must-read topics such as hip, groin and cartilage imaging; newly described impingements; and new concepts in the hip including teres ligament pathology. This publication is a key title in the popular Expert Radiology Series, which delivers evidence-based expert guidance from around the globe. Fully understand each topic with a format that delivers essential background information. Streamline the decision-making process with integrated protocols, classic signs, and ACR guidelines, as well as a design that structures every chapter consistently to include pathophysiology, imaging techniques, imaging findings, differential diagnosis, and treatment options. Write the most comprehensive reports possible with help from boxes highlighting what the referring physician needs to know, as well as suggestions for treatment and future imaging studies. Access in-depth case studies, valuable appendices, and additional chapters covering all of the most important musculoskeletal procedures performed today. Quickly locate important information with a full-color design that includes color-coded tables and bulleted lists highlighting key concepts, as well as color artwork that lets you easily find critical anatomic views of diseases and injuries. Engage with more than 40 brand-new videos, including arthroscopic videos. Easily comprehend complicated topics with over 5,000 images and new animations. Explore integrated clinical perspectives on the newest modalities such as PET-CT in cancer, diffusion MR, as well as ultrasonography, fusion imaging, multi-slice CT and nuclear medicine. Learn from team of international experts provides a variety of evidence-based guidance, including the pros and cons of each modality, to help you overcome difficult challenges. Consult this title on your favorite e-reader.

Download or read book Management of Temporomandibular Joint Degenerative Diseases written by Boudewijn Stegenga and published by Springer. This book was released on 2012-12-06 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is fashionable in professional circles to deplore the difficulty of intellectual discourse between "academicians" - men of letters, researchers, rationalist- and "practitioners" - surgeons, radiologists, physical therapists. How benefi cial it would be if educated non-academicians could speak intelligently about t-tests and chi-square tests and men of academia could appreciate the travail, spirit, and needs of a busy office and practice! Even this suspected gap between "two cultures" came very near together in the wonderful town of Groningen (The Netherlands) as wise men from both practice and scholarship gathered to talk about the unfathomables of the temporomandibular joint. There were keen discussions about the intense bio logical changes which occur about the complex temporomandibular joint after excessive use or injury. These papers were followed by talks outlining the experiences of those involved in the imaging and non-surgical and surgical management of patients who were enduring such changes. The pitch and interchange of opinions and evidence as to why a disc or its position could effect little or profound disturbance of the temporomandibular apparatus were en lightening to each who listened - and thought. And even more sobering was to hear the report of a well-documented, multiple decades long study of a large number of patients with osteoarthrosis and internal derangement which defined a natural course and eventual end of the disease. With this understanding, one is now faced with the obvious question of how much treatment patients with osteoarthrosis really require.

Download or read book Imaging of Arthritis and Metabolic Bone Disease written by Barbara N. W. Weissman and published by Elsevier Health Sciences. This book was released on 2009-01-01 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get state-of-the-art coverage of the full range of imaging techniques available to assist in the diagnosis and therapeutic management of rheumatic diseases. Written by acknowledged experts in musculoskeletal imaging, this richly illustrated, full-color text presents the latest diagnostic and disease monitoring modalities - MRI, CT, ultrasonography, nuclear medicine, DXA - as well as interventional procedures. You'll find comprehensive coverage of specific rheumatic conditions, including osteoarticular and extraarticular findings. This superb new publication puts you at the forefront of imaging in arthritis and metabolic bone disease - a must have reference for the clinician and imaging specialist. Includes all imaging modalities relevant to rheumatic disease, and applications and contraindications of each, for balanced coverage.Incorporates a user-friendly, consistent full-color format for quick and easy reference.Provides osteoarticular and extra-articular features and findings to show how imaging benefits diagnosis and management of complex rheumatologic conditions.Creates a one-stop shop with comprehensive coverage of imaging for all rheumatic conditions, including metabolic conditions and pediatric disorders.Presents interventional techniques-injections, arthrography, radiofrequency ablation-to create the perfect diagnostic and interventional clinical tool.