Download or read book Isolation and Characterisation of Phages Infecting Gram Positive Food Bacteria written by Wan-Jing Lee and published by . This book was released on 2008 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gram positive phages From isolation to application written by Jennifer Mahony and published by Frontiers Media SA. This book was released on 2015-05-15 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phage biology is one of the most significant and fundamental aspects of biological research and is often used as a platform for model studies relating to more complex biological entities. For this reason, phage biology has enjoyed focused attention and significant advances have been made in the areas of phage genomics, transcriptomics and the development and characterisation of phage-resistance mechanisms. In recent years, considerable research has been performed to increase our understanding of the interactions of these phages with their hosts using genomic, biochemical and structural approaches. Such multidisciplinary approaches are core to developing a full understanding of the processes that govern phage infection, information that may be harnessed to develop anti-phage strategies that may be applied in food fermentations or applied in a positive sense in phage therapy applications. The co-evolutionary processes of these phages and their hosts have also been a considerable focus of research in recent years. Such data has promoted a deeper understanding of the means by which these phages attach to and infect their hosts and permitted the development of effective anti-phage strategies. Furthermore, the presence and activity of host-encoded phage-resistance systems that operate at various stages of the phage cycle and the potential for the application of such systems consolidates the value of research in this area. Conversely, phages and their components have been applied as therapeutic agents against a number of pathogens including, among others, Clostridium difficile, Lactococcus garviae, Mycobacterium spp., Listeria spp. and the possibilities and limitations of these systems will be explored in this topic. Additionally, phage therapeutic approaches have been applied to the prevention of development of food spoilage organisms in the brewing and beverage sectors and exhonorate the positive applications of phages in the industrial setting. This research topic is aimed to address the most current issues as well as the most recent advances in the research of phages infecting Gram-positive bacteria covering areas such as phages in food fermentations, their impact in industry, phage ecology, genomics, evolution, structural analysis, phage-host interactions and the application of phages and components thereof as therapeutic agents against human and animal pathogens.
Download or read book Bacteriophages written by David R. Harper and published by Springer Nature. This book was released on 2021-01-30 with total page 1376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first major reference work dedicated to the mannifold industrial and medical applications of bacteriophages provides both theoretical and practical insights into the emerging field of bacteriophage biotechnology. The book introduces to bacteriophage biology, ecology and history and reviews the latest technologies and tools in bacteriophage detection, strain optimization and nanotechnology. Usage of bacteriophages in food safety, agriculture, and different therapeutic areas is discussed in detail. This book serves as essential guide for researchers in applied microbiology, biotechnology and medicine coming from both academia and industry.
Download or read book Bacteriophages written by Elizabeth Kutter and published by CRC Press. This book was released on 2004-12-28 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the emergence of pathogenic bacteria that cannot be treated with current antibiotics, many researchers are revisiting the use of bacteriophages, or phages, to fight multidrug-resistant bacteria. Bacteriophages: Biology and Applications provides unparalleled, comprehensive information on bacteriophages and their applications, such as
Download or read book Phage Ecology written by Sagar M. Goyal and published by Wiley-Interscience. This book was released on 1987-11-13 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first to explore the distribution, fate, and ecology of phage in the environment and point up the important applications of this information. The text begins with an historical overview, followed by a discussion of the current state of phage taxonomy. Next is covered the distribution patterns and fate of phage in diverse environments, e.g. soil, fresh water, marine water, and water and wastewater treatment plants. Factors that can influence the numbers and activity of phage populations, e.g. host and phage density, association of a phage with solids, presence of organic matter, temperature, pH, ultraviolet and visible light, concentration and types of ions present, and the metabolic activities of bacteria other than the phage host are examined. One chapter is devoted to the occurrence and implications of phage in various industries, e.g. dairy, wine, sausage, and antibiotic industries.
Download or read book Bacteriophages in the Control of Food and Waterborne Pathogens written by Parviz M. Sabour and published by American Society for Microbiology Press. This book was released on 2010-08-18 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gain a better understanding of how these fascinating microorganisms can help ensure a safe food supply. • Provides a unique comprehensive review of the literature on the application of bacteriophages as therapeutic and prophylactic agents in the food production and processing industries, including food animals, plants, and aquaculture. • Describes how bacteriophages function, explaining why they have the potential to be highly effective antimicrobials, and explores opportunities to use bacteriophages to detect bacterial contamination of foods and water and to control pathogens during both food production and processing. • Examines bacteriophages that can have a negative effect on industrial food processes and bacteriophages that potentially can lead to the evolution of foodborne pathogens; and covers safety and regulatory issues that are crucial to the success of bacteriophage use. • Serves as a resource for food microbiologists, food industry professionals, government regulators.
Download or read book The Bacteriophages written by Richard Calendar and published by Oxford University Press. This book was released on 2006 with total page 761 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative, timely, and comprehensively referenced compendium on the bacteriophages explores current views of how viruses infect bacteria. In combination with classical phage molecular genetics, new structural, genomic, and single-molecule technologies have rendered an explosion in our knowledge of phages. Bacteriophages, the most abundant and genetically diverse type of organism in the biosphere, were discovered at the beginning of the 20th century and enjoyed decades of used as anti-bacterial agents before being eclipsed by the antibiotic era. Since 1988, phages have come back into the spotlight as major factors in pathogenesis, bacterial evolution, and ecology. This book reveals their compelling elegence of function and their almost inconceivable diversity.Much of the founding work in molecular biology and structural biology was done on bacteriophages. These are widely used in molecular biology research and in biotechnology, as probes and markers, and in the popular method of assesing gene expression.
Download or read book Microbial Source Tracking written by Jorge W. Santo Domingo and published by Emerging Issues in Food Safety. This book was released on 2007 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a state-of-the-art review of the current technology and applications being utilized to identify sources of fecal contamination in waterways. - Serves as a useful reference for researchers in the food industry, especially scientists investigating etiological agents responsible for food contamination. - Provides background information on MST methods and the assumptions and limitations associated with their use. - Covers a broad range of topics related to MST, including environmental monitoring, public health and national security, population biology, and microbial ecology. - Offers valuable insights into future research directions and technology developments.
Download or read book Textbook of Diagnostic Microbiology written by Connie R. Mahon and published by Saunders. This book was released on 2011 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a solid introduction to the essentials of diagnostic microbiology, this accessible, full-color text helps you develop the problem-solving skills necessary for success in the clinical setting. A reader-friendly, "building block" approach to microbiology moves progressively from basic concepts to advanced understanding, guiding you through the systematic identification of etiologic agents of infectious diseases. Building block approach encourages recall of previously learned information, enhancing your critical and problem solving skills. Case in Point feature introduces case studies at the beginning of each chapter. Issues to Consider encourages you to analyze and comprehend the case in point. Key Terms provide a list of the most important and relevant terms in each chapter. Objectives give a measurable outcome to achieve by completing the material. Points to Remember summarize and help clearly identify key concepts covered in each chapter. Learning assessment questions evaluate how well you have mastered the material. New content addresses bone and joint infections, genital tract infections, and nosocomial infections. Significantly updated chapter includes current information on molecular biology and highlights content on multidrug resistant bacteria. Reorganized chapters accent the most relevant information about viruses and parasites that are also transmissible to humans. Case studies on the Evolve site let you apply the information that you learn to realistic scenarios encountered in the laboratory.
Download or read book Bacteriophages written by Martha R.J. Clokie and published by Humana Press. This book was released on 2017-11-15 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book expands on the previous volumes with new chapters exploring emerging themes and methodologies in bacterial virus research. The chapters in this book are divided into 4 parts and cover topics such as: iron chloride flocculation of bacteriophages from seawater; encapsulation of Listeria phage A511 by alginate; examining genome termini of bacteriophage through high-throughput sequencing; genome sequencing of dsDNA-containing bacteriophages directly from a single plaque; characterizing bacteriophages by biology, taxonomy, and genome analysis; phage genome annotation using the RAST pipeline; and the use of RP4::mini-Mu for gene transfer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and authoritative, Bacteriophages: Methods and Protocols, Volume III is a valuable resource for both established and novice phage scientists.
Download or read book Microbial Interactions written by J.L. Reissig and published by Springer Science & Business Media. This book was released on 2013-12-11 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiology has undergone a number of metamorphoses in its relatively brief existence. It has been in approximate succession, morphology, epidemiology, biochemistry, genetics, and molecular biology. It is also becoming a significant parcel of cell surface studies. The one embodiment which has remained elusiv- particularly for bacteriology - is the taxonomic one. This may have been a blessing in disguise because it encouraged microbiologists to deal with the general rather than the particular; promoting a search for unitary explanations, in the manner of Kluyver and van Niel, long before anyone knew about the universality of the genetic code, or could trace the genealogy of enzymes from the study of amino acid substitutions. . This volume is predicated on the idea that deep analogies underly the mech anisms of cellular interaction, and therefore belongs in the unitary tradition of microbiology. It occupies itself with a wide variety of micro-organisms, considering them from vantage points of considerable diversity, ranging from taxonomic irreverence to keen evolutionary awareness, and is concerned with areas which have developed independently of each other.
Download or read book Bacteriophage Applications Historical Perspective and Future Potential written by Jessica Nicastro and published by Springer. This book was released on 2016-10-04 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores key applications of phage biotechnology and reviews recent advances in phage display technologies. The applications covered were selected on the basis of their significance and representativeness in the field. The small size and enormous diversity of bacteriophages make them ideal candidates for numerous applications across many industries. Since the discovery of phages and the advent of phage display systems, considerable attention has been focused on the development of novel therapeutic and industrial applications. Recent studies combine the genomic flexibility of phages with phage display systems in order to generate modified phages for targeted delivery.
Download or read book Bacteriophage written by Stephen Mc Grath and published by Caister Academic Press Limited. This book was released on 2007 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by eminent international researchers actively involved in the disparate areas of bacteriophage research this book focuses on the current rapid developments in this exciting field.
Download or read book Bacteriophage Ecology written by Stephen T. Abedon and published by Cambridge University Press. This book was released on 2008-05-01 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteriophages, or phages, are viruses that infect bacteria and are believed to be the most abundant and genetically diverse organisms on Earth. As such, their ecology is vast both in quantitative and qualitative terms. Their abundance makes an understanding of phage ecology increasingly relevant to bacterial ecosystem ecology, bacterial genomics and bacterial pathology. Abedon provides the first text on phage ecology for almost 20 years. Written by leading experts, synthesizing the three key approaches to studying phage ecology, namely studying them in natural environments (in situ), experimentally in the lab, or theoretically using mathematical or computer models. With strong emphasis on microbial population biology and distilling cutting-edge research into basic principles, this book will complement other currently available volumes. It will therefore serve as an essential resource for graduate students and researchers, particularly those with an interest in phage ecology and evolutionary biology.
Download or read book Phage Therapy Past Present and Future written by Stephen T. Abedon and published by Frontiers Media SA. This book was released on 2017-09-05 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Historically, the first observation of a transmissible lytic agent that is specifically active against a bacterium (Bacillus anthracis) was by a Russian microbiologist Nikolay Gamaleya in 1898. At that time, however, it was too early to make a connection to another discovery made by Dmitri Ivanovsky in 1892 and Martinus Beijerinck in 1898 on a non-bacterial pathogen infecting tobacco plants. Thus the viral world was discovered in two of the three domains of life, and our current understanding is that viruses represent the most abundant biological entities on the planet. The potential of bacteriophages for infection treatment have been recognized after the discoveries by Frederick Twort and Felix d’Hérelle in 1915 and 1917. Subsequent phage therapy developments, however, have been overshadowed by the remarkable success of antibiotics in infection control and treatment, and phage therapy research and development persisted mostly in the former Soviet Union countries, Russia and Georgia, as well as in France and Poland. The dramatic rise of antibiotic resistance and especially of multi-drug resistance among human and animal bacterial pathogens, however, challenged the position of antibiotics as a single most important pillar for infection control and treatment. Thus there is a renewed interest in phage therapy as a possible additive/alternative therapy, especially for the infections that resist routine antibiotic treatment. The basis for the revival of phage therapy is affected by a number of issues that need to be resolved before it can enter the arena, which is traditionally reserved for antibiotics. Probably the most important is the regulatory issue: How should phage therapy be regulated? Similarly to drugs? Then the co-evolving nature of phage-bacterial host relationship will be a major hurdle for the production of consistent phage formulae. Or should we resort to the phage products such as lysins and the corresponding engineered versions in order to have accurate and consistent delivery doses? We still have very limited knowledge about the pharmacodynamics of phage therapy. More data, obtained in animal models, are necessary to evaluate the phage therapy efficiency compared, for example, to antibiotics. Another aspect is the safety of phage therapy. How do phages interact with the immune system and to what costs, or benefits? What are the risks, in the course of phage therapy, of transduction of undesirable properties such as virulence or antibiotic resistance genes? How frequent is the development of bacterial host resistance during phage therapy? Understanding these and many other aspects of phage therapy, basic and applied, is the main subject of this Topic.
Download or read book Antibiotic Drug Resistance written by José-Luis Capelo-Martínez and published by John Wiley & Sons. This book was released on 2019-09-24 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Download or read book Bacteriophages in Health and Disease written by Paul Hyman and published by CABI. This book was released on 2012 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteriophages are viruses that infect bacteria; as such, they have many potential uses for promoting health and combating disease. This book covers the many facets of phage-bacterial-human interaction in three sections: the role and impact of phages on natural bacterial communities, the potential to develop phage-based therapeutics and other aspects in which phages can be used to combat disease, including bacterial detection, bacterial epidemiology, the tracing of fecal contamination of water and decontamination of foods.
