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Book Involvement of Nitric Oxide in Osteoclastogenesis and Orthodontic Tooth Movement

Download or read book Involvement of Nitric Oxide in Osteoclastogenesis and Orthodontic Tooth Movement written by Dorrin Nilforoushan and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Involvement of Nitric Oxide in Osteoclast Formation and Orthodontic Tooth Movement

Download or read book Involvement of Nitric Oxide in Osteoclast Formation and Orthodontic Tooth Movement written by Dorrin Nilforoushan and published by . This book was released on 2009 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric oxide (NO) is a short lived free radical regulating bone turnover and bone cell function (1, 2). Osteoclasts are multinucleated bone resorbing cells which form by fusion of pre-osteoclasts. In addition, NO is a signaling molecule in mechanical loading of the bone (3), and in orthodontic tooth movement (OTM) (4). In OTM, force is applied to the tooth and transferred to the bone resulting in bone remodeling leading to tooth movement. This project has two parts: (1) NO in osteoclastogenesis: (a) An intense NO signal was observed in pre-osteoclasts preceding cell fusion. (b) Osteoclastogenesis increased when cells were exposed to the NOS inhibitor, L-NMMA, during their differentiation phase. (c) In contrast, pre-osteoclast fusion decreased in presence of to L-NMMA during the fusion phase. (d) NOS inhibitors, decreased osteoclast formation. (e) The inhibitory effect of L-NMMA on osteoclast formation was abolished with increasing concentrations of sRANKL. (f) NO donors increased osteoclast formation. (g) An increase in NO production coincided with pre-osteoclasts fusion. (h) Inhibiting fusion decreased osteoclast formation and NO production. (i) L-NMMA decreased, while NO donors increased actin free barbed ends. Conclusion: While NO initially negatively regulates pre-osteoclast differentiation, it later facilitates the fusion of mononuclear pre-osteoclasts, possibly by up regulating actin remodeling. (2) Involvement of NO in OTM: Differential expression of NOS isoforms was investigated in periodontal ligament (PDL) and bone in tension and pressure sides using immunohistochemistry with NOS isoforms in a rat model of OTM. (a) Expression of all isoforms was increased in the tension side. (b) iNOS and nNOS expressions in the pressure side with the cell free zone were decreased while in the pressure side without the cell free zone were increased. (c) The intensity of eNOS staining was increased in the tension side. (d) Duration of force only changed the pattern of nNOS expression. (e) Osteocyte NOS expression did not change. Conclusion: All NOS isoforms are involved in OTM with different expression patterns between the tension and pressure with nNOS being more involved in early OTM. PDL cells, rather than osteocytes are the mechanosensors in early OTM with regards to NO signaling.

Book Biological Mechanisms of Tooth Movement

Download or read book Biological Mechanisms of Tooth Movement written by Vinod Krishnan and published by John Wiley & Sons. This book was released on 2015-04-29 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Mechanisms of Tooth Movement, Second Edition is an authoritative reference to the scientific foundations underpinning clinical orthodontics. Led by an expert editor team and with contributions from an international group of contributors, the book covers key topics including bone biology, the effects of mechanical loading on tissues and cells, genetics, inflammation, tissue remodeling and the effects of diet, drugs, and systemic diseases. Highly-illustrated throughout, this second edition has been fully revised, updated and expanded to new developments in genomics, rapid orthodontics and current controversies in tooth movement research. Trainees, qualified specialists and researchers in orthodontics can rely on this comprehensive text to inform them about the clinical and scientific implications of the biological mechanisms involved in the movement of teeth.

Book Nitric Oxide in Bone and Joint Disease

Download or read book Nitric Oxide in Bone and Joint Disease written by Mika V. J. Hukkanen and published by Cambridge University Press. This book was released on 1998-10-15 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric oxide research has emerged as one of the most important areas in bone and joint diseases. First published in 1998, this book draws together knowledge on the actions of this mediator and its role in such common diseases as arthritis and osteoporosis. It introduces the basic biology and biochemistry of nitric oxide, the immune response and bone biology. It reviews in depth the facts we know today and the future promise of this exciting area of research. The book will give scientists and clinicians a unique insight into this increasingly important area. It also emphasises potential treatments which exploit our understanding of the role of nitric oxide in bone and joint disease.

Book Biological Mechanisms of Tooth Movement

Download or read book Biological Mechanisms of Tooth Movement written by Vinod Krishnan and published by John Wiley & Sons. This book was released on 2021-03-11 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Mechanisms of Tooth Movement This new edition continues to be an authoritative reference to the scientific foundations underpinning clinical orthodontics The newly and thoroughly revised Third Edition of Biological Mechanisms of Tooth Movement delivers a comprehensive reference for orthodontic trainees and specialists. It is fully updated to include new chapters on personalized orthodontics as well as the inflammatory process occurring in the dental and paradental tissues. It is heavily illustrated throughout, making it easier for readers to understand and retain the information discussed within. The topics covered range from bone biology, the effects of mechanical loading on tissues and cells, genetics, tissue remodeling, and the effects of diet, drugs, and systemic diseases. The Third Edition of Biological Mechanisms of Tooth Movement features seven sections that cover subjects such as: The development of biological concepts in orthodontics, including the cellular and molecular biology behind orthodontic tooth movement Mechanics meets biology, including the effects of mechanical loading on hard and soft tissues and cells, and biological reactions to temporary anchorage devices Inflammation and orthodontics, including markers for tissue remodeling in the gingival crevicular fluid and saliva Personalized diagnosis and treatment based on genomic criteria, including the genetic influences on orthodontic tooth movement Rapid orthodontics, including methods to accelerate or decelerate orthodontic tooth movement Perfect for residents and PhD students of orthodontic and periodontal programs, Biological Mechanisms of Tooth Movement is also useful to academics, clinicians, bone biologists, and researchers with an interest in the mechanics and biology of tooth movement.

Book Biology of Orthodontic Tooth Movement

Download or read book Biology of Orthodontic Tooth Movement written by Bhavna Shroff and published by Springer. This book was released on 2016-05-30 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​This book presents the current knowledge and understanding of the biological processes involved in the orthodontic movement of teeth and discusses recent progress in the field. It links research advances to their immediate clinical applications and offers researchers and clinicians a state of the art reference on topical issues relating to orthodontic tooth movement. Biological events play a central role in the movement of teeth during orthodontic therapy. The basis for understanding the sequence of cellular events that leads to orthodontic movement has been well established in the literature through the use of animal models. In recent years, researchers and clinicians have focused their efforts on developing treatment modalities to increase the speed of orthodontic treatment and provide better anchorage options for noncompliant patients. This book will be an invaluable aid in understanding the biology of tooth movement and the relevance of the latest concepts to clinical practice.

Book Tooth Movement

    Book Details:
  • Author : A. Kantarci
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2015-11-24
  • ISBN : 3318054801
  • Pages : 144 pages

Download or read book Tooth Movement written by A. Kantarci and published by Karger Medical and Scientific Publishers. This book was released on 2015-11-24 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the intention of improving the rate, quality, and stability of orthodontic tooth movement, those in the field are now moving toward accomplishing this 'acceleration' with minimally or non-invasive methods. New procedures have been widely tested in humans, animal models, and in vitro. While interest is growing both in the industry and at the clinical level, the understanding of the biology is limited. Considering that a simple increase in force will result in tooth morbidity and arrest of the tooth migration, a multi-disciplinary approach is critical for success. This publication brings together multi-disciplinary expertise on a wide variety of processes related to and involved in orthodontic tooth movement. The premise is that, by better understanding the biological structures and the mechanism through which they respond to biomechanical forces, one can get a better assessment of the 'acceleration'. This work presents research aimed at an improved understanding of conventional and accelerated orthodontic tooth movement from a biological perspective and will be of great value to clinicians, researchers, academics, and students.

Book Current Approaches in Orthodontics

Download or read book Current Approaches in Orthodontics written by and published by BoD – Books on Demand. This book was released on 2019-04-10 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides information on the current technological developments and new concepts in orthodontic treatment procedures. The main concepts of the book are scope innovations in accelerated tooth movement, new developments such as corticotomy, microperforations (MOP), piezosicion, photobiostimulation, laser in orthodontics, chemical agents, as well as complications and risks. The book contains interdisciplinary managements involving surgery first, cleft lip and palate therapy, orthognathic surgery, and obstructive sleep apnea. This internationally-recognized specialty is continuing to experience advancements in technology, instrumentation, and treatment methods.

Book Current Trends in Orthodontics

Download or read book Current Trends in Orthodontics written by and published by BoD – Books on Demand. This book was released on 2022-08-17 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores current trends in orthodontics. It covers a broad range of topics over four sections: “Current Evidence on Tooth Movement,” “Digitization and Workflow,” “Orthodontics Techniques and Trends,” and “Early Treatment.”

Book TEXTBOOK OF ORTHODONTICS   E Book

Download or read book TEXTBOOK OF ORTHODONTICS E Book written by Sridhar Premkumar and published by Elsevier Health Sciences. This book was released on 2015-04-25 with total page 781 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an effort to step up with the present changing scenarios of learning. It is the fruition of striking a balance between rejuvenated fundamentals of classical manuscripts, the fresh knowledge rich curriculum and tailored resource package with outstanding transparencies. It combines the strong foundation of basic core elements of orthodontic concepts, proper diagnosis and recognition of problems and exposure to treatment strategies and methodologies. It is a definite book for all dental undergraduates and an excellent supplement for all students undergoing postgraduate specialist training in orthodontics. - Covers syllabi prescribed by Dental Council of India (DCI) and International schools of dentistry - Provides more than 1500 line arts, flowcharts, tables and clinical photographs for easy perception of the subject and to illustrate vital principles and techniques - Chapters contain Clinical Significance boxes that encourage readers to relate and channelize the theory knowledge into clinical practice - Learning Exercises furnished in each chapter facilitates the students to assess themselves and reflect on what had been learnt - Synopsis of Treatment Planning for Different Malocclusions, the last chapter serves not only as a guide to recap the depth and breadth of factual comprehension but also to promote analysis, evaluation and judgment in orthodontic treatment philosophies

Book Advanced use of materials in orthodontics

Download or read book Advanced use of materials in orthodontics written by Domenico Ciavarella and published by Frontiers Media SA. This book was released on 2023-01-20 with total page 73 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Orthodontics  Current Principles and Techniques  First SA Edn

Download or read book Orthodontics Current Principles and Techniques First SA Edn written by Lee W. Graber and published by Elsevier Health Sciences. This book was released on 2016-12-01 with total page 1203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive, cutting-edge content prepares you for today's orthodontics! Orthodontics: Current Principles and Techniques: 1st South Asia Edition provides evidence-based coverage of orthodontic diagnosis, planning strategies, and treatment protocols, including esthetics, genetics, temporary anchorage devices, aligners, technology-assisted biomechanics, and much more. From respected editors Lee Graber, Robert Vanarsdall, Katherine Vig, and Greg Huang, along with a veritable Who's Who of expert contributors, this classic reference has a concise, no-nonsense approach to treatment that makes it the go-to book for orthodontic residents and practitioners - Comprehensive coverage provides a one-stop resource for the field of orthodontics, including foundational theory and the latest on the materials and techniques used in today's practice. - Experienced, renowned editors lead a team of expert, international contributors, bringing the most authoritative clinical practice and supporting science from the best and brightest in the industry. - More than 3,400 images include a mixture of radiographs, full-color clinical photos, and anatomic or schematic line drawings, showing examples of treatment, techniques, and outcomes. - Extensive references make it easy to look up the latest in orthodontic research and evidence-based information, and all references also appear online. - Detailed, illustrated case studies show the decision-making process, showing the consequences of various treatment techniques over time

Book Orthodontics   E Book

    Book Details:
  • Author : Lee W. Graber
  • Publisher : Elsevier Health Sciences
  • Release : 2016-07-15
  • ISBN : 0323444326
  • Pages : 1209 pages

Download or read book Orthodontics E Book written by Lee W. Graber and published by Elsevier Health Sciences. This book was released on 2016-07-15 with total page 1209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive, cutting-edge content prepares you for today's orthodontics! Orthodontics: Current Principles and Techniques, 6th Edition provides evidence-based coverage of orthodontic diagnosis, planning strategies, and treatment protocols, including esthetics, genetics, temporary anchorage devices, aligners, technology-assisted biomechanics, and much more. New to this edition is an Expert Consult website using videos and additional visuals to show concepts difficult to explain with words alone. Expert Consult also adds three online-only chapters, research updates, and a fully searchable version of the text. From respected editors Lee Graber, Robert Vanarsdall, Katherine Vig, and Greg Huang, along with a veritable Who's Who of expert contributors, this classic reference has a concise, no-nonsense approach to treatment that makes it the go-to book for orthodontic residents and practitioners! - Comprehensive coverage provides a one-stop resource for the field of orthodontics, including foundational theory and the latest on the materials and techniques used in today's practice. - Experienced, renowned editors lead a team of expert, international contributors, bringing the most authoritative clinical practice and supporting science from the best and brightest in the industry. - More than 3,400 images include a mixture of radiographs, full-color clinical photos, and anatomic or schematic line drawings, showing examples of treatment, techniques, and outcomes. - Extensive references make it easy to look up the latest in orthodontic research and evidence-based information, and all references also appear online. - Detailed, illustrated case studies show the decision-making process, showing the consequences of various treatment techniques over time. - NEW! Seven all-new chapters include Orthodontic Diagnosis and Treatment Planning with Cone-Beam Computed Tomography Imaging; Upper Airway, Cranial Morphology, and Sleep Apnea; Management of Impactions; Iatrogenic Effects of Orthodontic Appliances; Minimally and Non-Invasive Approaches to Accelerate Tooth Movement; Management of Dental Luxation and Avulsion Injuries in the Permanent Dentition; and Patient Management and Motivation for the Child and Adolescent Patient. - NEW! Expert Consult website includes online-only chapters, instructional videos, many references linked to PubMed, and research updates including additional case studies. - UPDATED CHAPTERS include Biomechanical Considerations with Temporary Anchorage Devices, Bonding in Orthodontics, Clear Aligner Treatment, Lingual Appliance Treatment, Psychological Aspects of Diagnosis and Treatment, Clinically Relevant Aspects of Dental Materials Science in Orthodontics, The Biologic Basis of Orthodontics, and more. - New co-editor Greg J. Huang is joined by new contributors who are highly regarded experts within their respective subspecialties in orthodontics.

Book The Role of Nitric Oxide in Cholesteatoma Induced Bone Resorption

Download or read book The Role of Nitric Oxide in Cholesteatoma Induced Bone Resorption written by Jae Yeon Jung and published by . This book was released on 2003 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Osteoclast and Osteoblast Activities During Early Orthodontic Tooth Movement and Acceleration of Tooth Movement Through the Targeting of Preosteoclasts with Exogenous Recombinant Mouse M CSF

Download or read book Osteoclast and Osteoblast Activities During Early Orthodontic Tooth Movement and Acceleration of Tooth Movement Through the Targeting of Preosteoclasts with Exogenous Recombinant Mouse M CSF written by Patricia Joyce Brooks and published by . This book was released on 2009 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoclasts and osteoblasts play critical roles in remodelling alveolar bone during orthodontic tooth movement (OTM). The objectives of this study were (i) To characterize the spatial/temporal pattern of osteoblast and osteoclast differentiation in the periodontal ligament (PDL) during OTM, and (ii) To determine if OTM acceleration could occur with PDL administration of an osteoclastic differentiation factor, Macrophage-Colony Stimulating Factor (M-CSF). Rat/mouse OTM models were used to characterize the expression of osteoblast and osteoclast differentiation markers. Expression of markers involved in recruiting osteoclast precursors and markers found on preosteoclasts, but not monocytes, were found in the PDL during early stages of OTM. We found up-regulated expression of genes downstream of M-CSF and an increase in OTM rate after M-CSF administration. Taken together, our results showed that improved knowledge of the molecular basis of cellular activities is critical towards the development and testing of pharmacological strategies as a means to accelerate OTM.