Download or read book Invertebrate Models of Natural and Drug Sensitive Reward written by Robert Huber and published by Frontiers Media SA. This book was released on 2019-10-17 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rewarding properties of drugs depend on their capacity to activate appetitive motivational states. Because the mechanisms underlying natural reward are an important life-sustaining process and strongly conserved throughout metazoan evolution, invertebrate models provide a powerful complement to the mammalian systems traditionally used in addiction research. A wide range of organizational complexity, combined with genetically manipulable, and relatively simple, accessible nervous systems, make invertebrates excellent models in which to explore general addiction principles. These include the role of natural reward systems in learning, the basic biological mechanisms of drug addiction, and the long-term effects of early drug exposure. The contributions to this e-book illustrate the current state of invertebrate addiction research. The chapters show that the reward circuits of invertebrate taxa are surprisingly sensitive to human drugs of abuse. Employing learning paradigms typically used in vertebrate studies (viz., conditioned place preference and operant, self-administration paradigms), invertebrates are shown to exhibit aspects of the addiction cycle from activational effects of common psychostimulants, sensitization with repeated application, to extinction, withdrawal, and reinstatement. This highlights the value of the comparative approach for both exploring conserved mechanisms underlying drug addiction and the utility of invertebrate models in seeking potential solutions.

Download or read book Methods of Behavior Analysis in Neuroscience written by Jerry J. Buccafusco and published by CRC Press. This book was released on 2000-08-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

Download or read book Neurobiology of Sensation and Reward written by Jay A. Gottfried and published by CRC Press. This book was released on 2011-03-28 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesizing coverage of sensation and reward into a comprehensive systems overview, Neurobiology of Sensation and Reward presents a cutting-edge and multidisciplinary approach to the interplay of sensory and reward processing in the brain. While over the past 70 years these areas have drifted apart, this book makes a case for reuniting sensation a

Download or read book Healing Moments in Psychotherapy Norton Series on Interpersonal Neurobiology written by Daniel J. Siegel and published by W. W. Norton & Company. This book was released on 2013-11-18 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Distinguished clinicians explain what lies at the heart of change in effective psychotherapy. A wide range of distinguished scientists and clinicians discuss the nature of change in the therapeutic process. Jaak Panksepp, Ian McGilchrist, Ruth Lanius, Francine Shapiro, and other luminaries offer readers a powerful journey through mindful awareness, neural integration, affective neuroscience, and therapeutic presence to reveal the transformational nature of therapy. Healing Moments in Psychotherapy dives deep into the art and science of healing from the perspective of a variety of clinical approaches and scientific viewpoints, including interpersonal neurobiology. Through the voices of a dozen clinicians and scientists presenting their combined experiences and wisdom, it serves as a window into the process of healing. Practical examples and empowering research data support the ways in which therapeutic relationships can help catalyze health and restore wellness within psychotherapy.

Download or read book Categorical Versus Dimensional Models of Affect written by Ralph D. Ellis and published by John Benjamins Publishing. This book was released on 2012 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most important theoretical and empirical issues in the scholarly study of emotion is whether there is a correct list of “basic” types of affect or whether all affective states are better modeled as a combination of locations on shared underlying dimensions. Many thinkers have written on this topic, yet the views of two scientists in particular are dominant. The first is Jaak Panksepp, the father of Affective Neuroscience. Panksepp conceptualizes affect as a set of distinct categories. The leading proponent of the dimensional approach in scientific psychology is James Russell. According to Russell all affect can be decomposed into two underlying dimensions, pleasure versus displeasure and low arousal versus high arousal. In this volume Panksepp and Russell each articulate their positions on eleven fundamental questions about the nature of affect followed by a discussion of these target papers by noted emotion theorists and researchers. Russell and Panksepp respond both to each other and to the commentators. The discussion leads to some stark contrasts, with formidable arguments on both sides, and some interesting convergences between the two streams of work.

Download or read book Use of Laboratory Animals in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

Download or read book Drunk Flies and Stoned Dolphins written by One R. Pagan and published by BenBella Books. This book was released on 2021-11-16 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the cup of coffee that jumpstarts the day to dangerously addictive drugs, the recreational use of plants with psychoactive properties has a long history among humans. But, as with many things, it turns out that other animals got there first. From parrots to primates, consuming medicinal chemicals is an instinctive behavior that helps countless organisms fight infection and treat disease. But the similarities don't end there: Like us, many creatures also consume substances that have no apparent benefit . . . except for inducing intoxication. In fact, animals have been using drugs for recreational purposes since prehistoric times. We may even have animals to thank for the idea—legend says that coffee was discovered by observing the behavior of goats that had eaten it. In his previous book, Strange Survivors, author and biologist Oné R. Pagán introduced readers to some of the truly bizarre strategies animals use to survive in the cutthroat world of natural selection. Now, in Drunk Flies and Stoned Dolphins, he sheds light on the surprising cravings they indulge when it's time to unwind. In this book, you'll get an eye-opening glimpse into the mind-altering behavior of the non-human members of the animal kingdom, spanning insects to elephants—including the dolphin species that apparently likes to pass around an intoxicating pufferfish as if they were sharing a joint. Combining fascinating science with humor and enthusiasm, Pagán's latest is full of the kind of unforgettable stories and odd facts that you'll find yourself repeating to everyone you meet. From fruit fly happy hour to the evolutionary reasons behind nature's drugs, Drunk Flies and Stoned Dolphins takes you on a trip through the colorful world of animal intoxication—and along the way, explores what this science reveals about the surprising connections between all the world's creatures.

Download or read book Encyclopedia of the Mind written by Harold Pashler and published by SAGE. This book was released on 2013-01-14 with total page 897 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's hard to conceive of a topic of more broad and personal interest than the study of the mind. In addition to its traditional investigation by the disciplines of psychology, psychiatry, and neuroscience, the mind has also been a focus of study in the fields of philosophy, economics, anthropology, linguistics, computer science, molecular biology, education, and literature. In all these approaches, there is an almost universal fascination with how the mind works and how it affects our lives and our behavior. Studies of the mind and brain have crossed many exciting thresholds in recent years, and the study of mind now represents a thoroughly cross-disciplinary effort. Researchers from a wide range of disciplines seek answers to such questions as: What is mind? How does it operate? What is consciousness? This encyclopedia brings together scholars from the entire range of mind-related academic disciplines from across the arts and humanities, social sciences, life sciences, and computer science and engineering to explore the multidimensional nature of the human mind.

Download or read book The Archaeology of Mind written by Jaak Panksepp and published by W. W. Norton & Company. This book was released on 2012-09-11 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: Care: sources of maternal nurturance --

Download or read book Marijuana and Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 1999-07-10 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The medical use of marijuana is surrounded by a cloud of social, political, and religious controversy, which obscures the facts that should be considered in the debate. This book summarizes what we know about marijuana from evidence-based medicineâ€"the harm it may do and the relief it may bring to patients. The book helps the reader understand not only what science has to say about medical marijuana but also the logic behind the scientific conclusions. Marijuana and Medicine addresses the science base and the therapeutic effects of marijuana use for medical conditions such as glaucoma and multiple sclerosis. It covers marijuana's mechanism of action, acute and chronic effects on health and behavior, potential adverse effects, efficacy of different delivery systems, analysis of the data about marijuana as a gateway drug, and the prospects for developing cannabinoid drugs. The book evaluates how well marijuana meets accepted standards for medicine and considers the conclusions of other blue-ribbon panels. Full of useful facts, this volume will be important to anyone interested in informed debate about the medical use of marijuana: advocates and opponents as well as policymakers, regulators, and health care providers.

Download or read book Minding the Climate written by Ann-Christine Duhaime and published by Harvard University Press. This book was released on 2022-10-18 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: A neurosurgeon explores how our tendency to prioritize short-term consumer pleasures spurs climate change, but also how the brain’s amazing capacity for flexibility can—and likely will—enable us to prioritize the long-term survival of humanity. Increasingly politicians, activists, media figures, and the public at large agree that climate change is an urgent problem. Yet that sense of urgency rarely translates into serious remedies. If we believe the climate crisis is real, why is it so difficult to change our behavior and our consumer tendencies? Minding the Climate investigates this problem in the neuroscience of decision-making. In particular, Ann-Christine Duhaime, MD, points to the evolution of the human brain during eons of resource scarcity. Understandably, the brain adapted to prioritize short-term survival over more uncertain long-term outcomes. But the resulting behavioral architecture is poorly suited to the present, when scarcity is a lesser concern and slow-moving, novel challenges like environmental issues present the greatest danger. Duhaime details how even our acknowledged best interests are thwarted by the brain’s reward system: if a behavior isn’t perceived as immediately beneficial, we probably won’t do it—never mind that we “know” we should. This is what happens when we lament climate change while indulging the short-term consumer satisfactions that ensure the disaster will continue. Luckily, we can sway our brains, and those of others, to alter our behaviors. Duhaime describes concrete, achievable interventions that have been shown to encourage our neurological circuits to embrace new rewards. Such small, incremental steps that individuals take, whether in their roles as consumers, in the workplace, or in leadership positions, are necessary to mitigate climate change. The more we understand how our tendencies can be overridden by our brain’s capacity to adapt, Duhaime argues, the more likely we are to have a future.

Download or read book Principles of Animal Behavior 4th Edition written by Lee Alan Dugatkin and published by University of Chicago Press. This book was released on 2020-01-15 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the last edition of this definitive textbook was published in 2013, much has happened in the field of animal behavior. In this fourth edition, Lee Alan Dugatkin draws on cutting-edge new work not only to update and expand on the studies presented, but also to reinforce the previous editions’ focus on ultimate and proximate causation, as well as the book’s unique emphasis on natural selection, learning, and cultural transmission. The result is a state-of-the-art textbook on animal behavior that explains underlying concepts in a way that is both scientifically rigorous and accessible to students. Each chapter in the book provides a sound theoretical and conceptual basis upon which the empirical studies rest. A completely new feature in this edition are the Cognitive Connection boxes in Chapters 2–17, designed to dig deep into the importance of the cognitive underpinnings to many types of behaviors. Each box focuses on a specific issue related to cognition and the particular topic covered in that chapter. As Principles of Animal Behavior makes clear, the tapestry of animal behavior is created from weaving all of these components into a beautiful whole. With Dugatkin’s exquisitely illustrated, comprehensive, and up-to-date fourth edition, we are able to admire that beauty anew.

Download or read book The Emotional Foundations of Personality A Neurobiological and Evolutionary Approach written by Kenneth L. Davis and published by W. W. Norton & Company. This book was released on 2018-03-27 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: A CHOICE Magazine Outstanding Academic Title of 2018. A novel approach to understanding personality, based on evidence that we share more than we realize with other mammals. This book presents the wealth of scientific evidence that our personality emerges from evolved primary emotions shared by all mammals. Yes, your dog feels love—and many other things too. These subcortically generated emotions bias our actions, alter our perceptions, guide our learning, provide the basis for our thoughts and memories, and become regulated over the course of our lives. Understanding personality development from the perspective of mammals is a groundbreaking approach, and one that sheds new light on the ways in which we as humans respond to life events, both good and bad. Jaak Panksepp, famous for discovering laughter in rats and for creating the field of affective neuroscience, died in April 2017. This book forms part of his lasting legacy and impact on a wide range of scientific and humanistic disciplines. It will be essential reading for anyone trying to understand how we act in the world, and the world’s impact on us.

Download or read book Conn s Handbook of Models for Human Aging written by Jeffrey L. Ram and published by Academic Press. This book was released on 2018-04-05 with total page 1220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated edition is designed as the only comprehensive, current work that covers the diversity in aging models. Chapters on comparative models explore age-related diseases, including Alzheimer's, joint disease, cataracts, cancer and obesity. Also included are new tricks and approaches not available in primary publications. This must-have handbook is an indispensable resource for researchers interested in the mechanisms of aging, gerontologists, health professionals, allied health practitioners and students. - Combines both the methods of study for human aging and animal models - Provides a historical overview and discussion of model availability, key methods and ethical issues - Contains over 200 full color illustrations

Download or read book Human Animal Interactions in Zoos written by Eduardo J. Fernandez and published by CABI. This book was released on 2024-05-30 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past couple of decades, Animal-Visitor Interactions (AVI), a type of Human-Animal Interaction (HAI), have become one of the major topics of interest for researchers working in zoos, especially in relation to animal welfare. This thought-provoking book summarizes the latest research concerning the impacts on HAIs in zoos, including the effects of visitors on animals and the effects of animals, exhibits, and the place itself on visitors. An invaluable resource for ethologists and animal behaviour and welfare students and practitioners, as well as social scientists and indeed anyone working with zoo animals.