Download or read book Integrated Nanoneedle microfluidic System for Single Cell Intracellular Temperature Measurement written by Salma Abdullah Shaaban Binsilm and published by . This book was released on 2015 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Micro Nanofluidic Devices for Single Cell Analysis written by Fan-Gang Tseng and published by MDPI. This book was released on 2018-10-04 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Micro/Nanofluidic Devices for Single Cell Analysis" that was published in Micromachines
Download or read book Interrogating Immune Signaling at Single cell Resolution Using Microfluidic Systems written by Meiye Wu and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammalian cell populations are heterogeneous and plastic in their response to stimuli and communication with each other. Multi-parameter quantitative experimental and computational methods that preserve single-cell resolution in these complex cell populations are necessary for elucidating the highly dynamic mechanisms that underlie cell signaling. This thesis explores various aspects of immune cell signaling using integrated microfluidic lab-on-a-chip technologies, capable of generating such multi-parameter single-cell measurements. A brief survey of existing single-cell resolution techniques and their applications in cell signaling studies, including microfluidic devices that evolved into those used in this thesis is discussed. Three microfluidic methods are developed for studying innate and adaptive immune cell signaling. The first method enables the spatiotemporal profiling of the toll-like receptor 4 (TLR4) pathway using a microfluidic device that seamlessly integrates cell culture, sample preparation, imaging and flow cytometry capabilities. Systems-level profiling of signaling proteins in the TLR4 pathway is performed in a single experiment on the integrated microfluidic platform, to generate data used for subsequent mathematical modeling. Next, a new single-cell resolution microfluidic method that combines metabolic labeling of bioorthogonal probes and proximity ligation assay to measure dynamically glycosylated proteins, a post-translational modification with widespread significance in cell signaling modulation, is demonstrated in T cells. The third method extends the utility of the microfluidic platform to measure microRNAs concurrently with proteins in intact T cells, to further expand the repertoire of signaling molecules that can be multiplexed and quantified at single-cell resolution. The lab-on-a-chip technologies developed in this thesis present potential uses for several important applications including basic research, drug and biomarker discovery, biodefense, and for development of cost-effective point-of-care clinical diagnostics.
Download or read book Vibrating Nanoneedle and Lab on chip Microfluidics System for Single Cell Mechanics written by Md. Habibur Rahman and published by . This book was released on 2015 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Integrated Temperature Measurement and Control in Polymer Microfluidic Systems written by and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current and Future Aspects of Nanomedicine written by Islam Khalil and published by BoD – Books on Demand. This book was released on 2020-05-06 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedicine refers to the use of nanotechnological applications in biomedical fields such as therapeutics, diagnostics, monitoring, visualization, tissue engineering and even surgery. This book presents recent updates in the nanomedicine market and discusses several aspects of drug delivery and tissue regeneration using different platforms and devices.
Download or read book Advanced Mechatronics and MEMS Devices II written by Dan Zhang and published by Springer. This book was released on 2016-10-18 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the state-of-the-art technologies in mechatronics, robotics, and MEMS devices in order to improve their methodologies. It provides a follow-up to "Advanced Mechatronics and MEMS Devices" (2013) with an exploration of the most up-to-date technologies and their applications, shown through examples that give readers insights and lessons learned from actual projects. Researchers on mechatronics, robotics, and MEMS as well as graduate students in mechanical engineering will find chapters on: Fundamental design and working principles on MEMS accelerometers Innovative mobile technologies Force/tactile sensors development Control schemes for reconfigurable robotic systems Inertial microfluidics Piezoelectric force sensors and dynamic calibration techniques ...And more. Authors explore applications in the areas of agriculture, biomedicine, advanced manufacturing, and space. Micro-assembly for current and future industries is also considered, as well as the design and development of micro and intelligent manufacturing.
Download or read book Advanced Healthcare Materials written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2014-05-09 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers
Download or read book Semiconducting Silicon Nanowires for Biomedical Applications written by Jeffery L. Coffer and published by Woodhead Publishing. This book was released on 2021-09-14 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: In its second, extensively revised second edition, Semiconducting Silicon Nanowires for Biomedical Applications reviews the fabrication, properties, and biomedical applications of this key material. The book begins by reviewing the basics of growth, characterization, biocompatibility, and surface modification of semiconducting silicon nanowires. Attention then turns to use of these structures for tissue engineering and delivery applications, followed by detection and sensing. Reflecting the evolution of this multidisciplinary subject, several new key topics are highlighted, including our understanding of the cell-nanowire interface, latest advances in associated morphologies (including silicon nanoneedles and nanotubes for therapeutic delivery), and significantly, the status of silicon nanowire commercialization in biotechnology. Semiconducting Silicon Nanowires for Biomedical Applications is a comprehensive resource for biomaterials scientists who are focused on biosensors, drug delivery, and the next generation of nano-biotech platforms that require a detailed understanding of the cell-nanowire interface, along with researchers and developers in industry and academia who are concerned with nanoscale biomaterials, in particular electronically-responsive structures. - Reviews the growth, characterization, biocompatibility, and surface modification of semiconducting silicon nanowires - Describes silicon nanowires for tissue engineering and delivery applications, including cellular binding & internalization, tissue engineering scaffolds, mediated differentiation of stem cells, and silicon nanoneedles & nanotubes for delivery of small molecule / biologic-based therapeutics - Highlights the use of silicon nanowires for detection and sensing - Presents a detailed description of our current understanding of the cell-nanowire interface - Covers the current status of commercial development of silicon nanowire-based platforms
Download or read book Second Harmonic Generation Imaging written by Francesco S. Pavone and published by Taylor & Francis. This book was released on 2016-04-19 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Second-harmonic generation (SHG) microscopy has shown great promise for imaging live cells and tissues, with applications in basic science, medical research, and tissue engineering. Second Harmonic Generation Imaging offers a complete guide to this optical modality, from basic principles, instrumentation, methods, and image analysis to biomedical a
Download or read book Nanobiotechnology written by Jameel M. Al-Khayri and published by Springer Nature. This book was released on 2021-07-22 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides up-to-date knowledge of the promising field of Nanobiotechnology with emphasis on the mitigation approaches to combat plant abiotic stress factors, including drought, salinity, waterlog, temperature extremes, mineral nutrients, and heavy metals. These factors adversely affect the growth as well as yield of crop plants worldwide, especially under the global climate change. Nanobiotechnology is viewed to revolutionize crop productivity in future. The chapters discuss the status and prospects of this cutting-edge technology toward understanding tolerance mechanisms, including signaling molecules and enzymes regulation in addition to the applications of Nanobiotechnology to combat individual abiotic stress factors.
Download or read book Introduction to Cell Mechanics and Mechanobiology written by Christopher R. Jacobs and published by Garland Science. This book was released on 2012-11-16 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Cell Mechanics and Mechanobiology is designed for a one-semester course in the mechanics of the cell offered to advanced undergraduate and graduate students in biomedical engineering, bioengineering, and mechanical engineering. It teaches a quantitative understanding of the way cells detect, modify, and respond to the physical prope
Download or read book CMBEBIH 2019 written by Almir Badnjevic and published by Springer. This book was released on 2019-05-10 with total page 731 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume gathers the proceedings of the International Conference on Medical and Biological Engineering, which was held from 16 to 18 May 2019 in Banja Luka, Bosnia and Herzegovina. Focusing on the goal to ‘Share the Vision’, it highlights the latest findings, innovative solutions and emerging challenges in the field of Biomedical Engineering. The book covers a wide range of topics, including: biomedical signal processing, medical physics, biomedical imaging and radiation protection, biosensors and bioinstrumentation, bio-micro/nano technologies, biomaterials, biomechanics, robotics and minimally invasive surgery, and cardiovascular, respiratory and endocrine systems engineering. Further topics include bioinformatics and computational biology, clinical engineering and health technology assessment, health informatics, e-health and telemedicine, artificial intelligence and machine learning in healthcare, as well as pharmaceutical and genetic engineering. Given its scope, the book provides academic researchers, clinical researchers and professionals alike with a timely reference guide to measures for improving the quality of life and healthcare.
Download or read book Two Dimensional Transition Metal Dichalcogenides written by Narayanasamy Sabari Arul and published by Springer. This book was released on 2019-07-30 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents advanced synthesis techniques adopted to fabricate two-dimensional (2D) transition metal dichalcogenides (TMDs) materials with its enhanced properties towards their utilization in various applications such as, energy storage devices, photovoltaics, electrocatalysis, electronic devices, photocatalysts, sensing and biomedical applications. It provides detailed coverage on everything from the synthesis and properties to the applications and future prospects of research in 2D TMD nanomaterials.
Download or read book Physics of the Life Sciences written by Jay Newman and published by Springer Science & Business Media. This book was released on 2010-03-23 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each chapter has three types of learning aides for students: open-ended questions, multiple-choice questions, and quantitative problems. There is an average of about 50 per chapter. There are also a number of worked examples in the chapters, averaging over 5 per chapter, and almost 600 photos and line drawings.
Download or read book Nano Antimicrobials written by Nicola Cioffi and published by Springer Science & Business Media. This book was released on 2012-02-26 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a high demand for antimicrobials for the treatment of new and emerging microbial diseases. In particular, microbes developing multidrug resistance have created a pressing need to search for a new generation of antimicrobial agents, which are effective, safe and can be used for the cure of multidrug-resistant microbial infections. Nano-antimicrobials offer effective solutions for these challenges; the details of these new technologies are presented here. The book includes chapters by an international team of experts. Chemical, physical, electrochemical, photochemical and mechanical methods of synthesis are covered. Moreover, biological synthesis using microbes, an option that is both eco-friendly and economically viable, is presented. The antimicrobial potential of different nanoparticles is also covered, bioactivity mechanisms are elaborated on, and several applications are reviewed in separate sections. Lastly, the toxicology of nano-antimicrobials is briefly assessed.
Download or read book Photon Upconversion Nanomaterials written by Fan Zhang and published by Springer. This book was released on 2014-12-11 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the latest advances made in both fundamental studies and potential applications of upconversion nanomaterials, particularly in the field of high-resolution in vitro bioanalysis and in vivo imaging. This book starts with the synthesis and characterization, and focuses on applications ranging from materials science to biology. Above all, it describes cutting-edge advances in upconversion nanophosphor (UCNP)-based applications in multiplexed encoding, guest delivery and release systems, photodynamic therapy (PDT), solar cells, photocatalysis and so on. The major barriers that currently prevent UCNPs from being used in mainstream applications are also presented in detail.
