Download or read book In vivo High Resolution Magnetic Resonance Imaging of the Skin and the Effect of Hydration written by Fakhereh Mirrashed and published by . This book was released on 1998 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book In Vivo High resolution Magnetic Resonance Imaging written by Joelle Barral and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging is a powerful, non-invasive modality that provides excellent soft-tissue contrast, but it suffers from a relatively low signal-to-noise ratio and is inherently prone to artifacts. Although technological progress over the last few decades has dramatically enhanced the resolution and quality of magnetic resonance images, specific clinical challenges highlight the need for further improvements. First, patients with peripheral arterial disease are at high risk for developing skin ulcers, which are often detected at a late stage, when amputation is the only treatment option. High-resolution imaging might detect changes in skin early enough to enable alternative treatments. Second, higher-resolution larynx imaging is highly desirable for the exact assessment of cartilage invasion, which is a critical step in cancer staging and in the selection of the appropriate treatment. High-resolution skin and larynx magnetic resonance imaging poses specific engineering challenges. The resolution of magnetic resonance images is first hampered by insufficient signal-to-noise ratio. Dedicated surface coils and/or higher field strengths overcome this limitation. Receive-only and transmit/receive 1-inch-diameter coils are shown to be suitable for skin imaging at 1.5 T, 3 T, and 7 T, and a dedicated three-channel array for larynx imaging provides a dramatic increase in resolution over the conventionally used 8-channel neurovascular array. The next engineering challenge involves eliminating artifacts from high-resolution images. Chemical shift artifacts are a concern in skin imaging, especially at higher field strengths, because the hypodermis is a fat layer. A multi-echo sequence is introduced that separates fat and water and provides good signal-to-noise ratio for all skin layers. Motion artifacts affect both skin and larynx images. In skin, where motion is usually rigid-body, navigator-based motion correction proves effective, and navigators can be integrated into the multi-echo sequence that separates fat and water. In larynx, where motion is complex, a new real-time algorithm combining a reacquisition strategy with navigator-based motion correction accounts for the different types of motion. One additional concern with skin imaging at higher field strengths is the increase in the spin-lattice relaxation time T1, which compromises the signal-to-noise ratio. Robust T1 mapping requires the use of a 4-parameter model. A novel nonlinear Least-Squares algorithm reduces the complex minimization problem to a straightforward 1D search, making the fitting procedure much faster. T1 mapping performed in skin at 1.5 T, 3 T, and 7 T shows that the increase in T1 slightly attenuates the benefits of higher field strengths but does not offset them.

Download or read book Microscopic Magnetic Resonance Imaging written by Luisa Ciobanu and published by CRC Press. This book was released on 2017-09-08 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past two decades, significant advances in magnetic resonance microscopy (MRM) have been made possible by a combination of higher magnetic fields and more robust data acquisition technologies. This technical progress has enabled a shift in MRM applications from basic anatomical investigations to dynamic and functional studies, boosting the use of MRM in biological and life sciences. This book provides a simple introduction to MRM emphasizing practical aspects relevant to high magnetic fields. It focuses on biological applications and presents a number of selected examples of neuroscience applications. The text is mainly intended for those who are beginning research in the field of MRM or are planning to incorporate high-resolution MRI in their neuroscience studies.

Download or read book In Vivo NMR Spectroscopy written by Robin A. de Graaf and published by John Wiley & Sons. This book was released on 2019-03-11 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents basic concepts, experimental methodology and data acquisition, and processing standards of in vivo NMR spectroscopy This book covers, in detail, the technical and biophysical aspects of in vivo NMR techniques and includes novel developments in the field such as hyperpolarized NMR, dynamic 13C NMR, automated shimming, and parallel acquisitions. Most of the techniques are described from an educational point of view, yet it still retains the practical aspects appreciated by experimental NMR spectroscopists. In addition, each chapter concludes with a number of exercises designed to review, and often extend, the presented NMR principles and techniques. The third edition of In Vivo NMR Spectroscopy: Principles and Techniques has been updated to include experimental detail on the developing area of hyperpolarization; a description of the semi-LASER sequence, which is now a method of choice; updated chemical shift data, including the addition of 31P data; a troubleshooting section on common problems related to shimming, water suppression, and quantification; recent developments in data acquisition and processing standards; and MatLab scripts on the accompanying website for helping readers calculate radiofrequency pulses. Provide an educational explanation and overview of in vivo NMR, while maintaining the practical aspects appreciated by experimental NMR spectroscopists Features more experimental methodology than the previous edition End-of-chapter exercises that help drive home the principles and techniques and offer a more in-depth exploration of quantitative MR equations Designed to be used in conjunction with a teaching course on the subject In Vivo NMR Spectroscopy: Principles and Techniques, 3rd Edition is aimed at all those involved in fundamental and/or diagnostic in vivo NMR, ranging from people working in dedicated in vivo NMR institutes, to radiologists in hospitals, researchers in high-resolution NMR and MRI, and in areas such as neurology, physiology, chemistry, and medical biology.

Download or read book Magnetic Resonance Imaging written by Pottumarthi V. Prasad and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading experts in the use of MRI explain its basic principles and demonstrate its power to understand biological processes with numerous cutting-edge applications. To illustrate its capability to reveal exquisite anatomical detail, the authors discuss MRI applications to developmental biology, mouse phenotyping, and fiber architecture. MRI can also provide information about organ and tissue function based on endogenous cantrast mechanisms. Examples of brain, kidney, and cardiac function are included, as well as applications to neuro and tumor pathophysiology. In addition, the volume demonstrates the use of exogenous contrast material in functional assessment of the lung, noninvasive evaluation of tissue pH, the imaging of metabolic activity or gene expression that occur on a molecular level, and cellular labeling using superparamagnetic iron oxide contrast agents.

Download or read book Ultra High Field Neuro MRI written by Karin Markenroth Bloch and published by Elsevier. This book was released on 2023-08-21 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultra-High Field Neuro MRI is a comprehensive reference and educational resource on the current state of neuroimaging at ultra-high field (UHF), with an emphasis on 7T. Sections cover the MR physics aspects of UHF, including the technical challenges and practical solutions that have enabled the rapid growth of 7T MRI. Individual chapters are dedicated to the different techniques that most strongly benefit from UHF, as well as chapters with a focus on different application areas in anatomical, functional and metabolic imaging. Finally, several chapters highlight the neurological and psychiatric applications for which 7T has shown benefits. The book is aimed at scientists who develop MR technologies and support clinical and neuroscience research, as well as users who want to benefit from UHF neuro MR techniques in their work. It also provides a comprehensive introduction to the field. Presents the opportunities and technical challenges presented by MRI at ultra-high field Describes advanced ultra-high field neuro MR techniques for clinical and neuroscience applications Enables the reader to critically assess the specific UHF advantages over currently available techniques at clinical field strengths

Download or read book Atlas of the Human Brainstem written by George Paxinos and published by Elsevier. This book was released on 2013-10-22 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Work on the human brainstem has been impeded by the unavailability of a comprehensive diagrammatic and photographic atlas. In the authors' preliminary work on the morphology of the human brainstem (The Human Nervous System, 1990), Paxinos et al demonstrated that it is possible to use chemoarchitecture to establish a number of human homologs in structures known to exist in the rat, the most extensively studied species. Now, with the first detailed atlas on the human brainstem in more than forty years, the authors present an accurate, comprehensive, and convenient reference for students, researchers, and pathologists. Key Features * The first detailed atlas on the human brainstem in more than forty years * Delineated as accurately as The Rat Brain in Stereotaxic Coordinates, Second Edition (Paxinos/Watson, 1986), the most cited book in neuroscience * Based on a single brain from a 59-year-old male with no medical history of neurological or psychiatric illness * Represents all areas of the medulla, pons, and midbrain in the plane transverse to the longitudinal axis of the brainstem * Consists of 64 plates and 64 accompanying diagrams with an interplate distance of half a millimeter * The photographs are of Nissl and acetylcholinesterase (AChE) stained sections at alternate levels * Establishes systematically the human homologs to nuclei identified in the brainstem of the rat Reviewed by leading neuroanatomists * An accurate and convenient guide for students, researchers, and pathologists

Download or read book High Spatial Resolution Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging written by Susan Moyher Noworolski and published by . This book was released on 1999 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Techniques for in Vivo High resolution MR Imaging of Connective Tissue Microstructure written by Hee Kwon Song and published by . This book was released on 1999 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book High Resolution Neuroimaging written by Ahmet Mesrur Halefoğlu and published by BoD – Books on Demand. This book was released on 2018-03-14 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Ahmet Mesrur Halefoğlu mostly deals with research fields in body imaging and neuroradiology with multidetector computed tomography and high-resolution magnetic resonance imaging. He has served as postdoctoral research fellow at Johns Hopkins Hospital. Currently, he is working as an associate professor of radiology in Istanbul, Turkey. He has more than 50 high-impact-factor publications and has written 3 book chapters. He is a member of Turkish Society of Radiology and European Society of Radiology. During the recent years, there have been major breakthroughs in MRI due to developments in scanner technology and pulse sequencing. These important achievements have led to remarkable improvements in neuroimaging and advanced techniques, including diffusion imaging, diffusion tensor imaging, perfusion imaging, magnetic resonance spectroscopy, and functional MRI. These advanced neuroimaging techniques have enabled us to achieve invaluable insights into tissue microstructure, microvasculature, metabolism, and brain connectivity.

Download or read book Ultra High Field Magnetic Resonance Imaging written by Pierre-Marie Robitaille and published by Springer Science & Business Media. This book was released on 2007-12-31 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: The foundation for understanding the function and dynamics of biological systems is not only knowledge of their structure, but the new methodologies and applications used to determine that structure. This volume in Biological Magnetic Resonance emphasizes the methods that involve Ultra High Field Magnetic Resonance Imaging. It will interest researchers working in the field of imaging.

Download or read book Applications of Ultra high field Magnetic Resonance Imaging MRI and Proton Magnetic Resonance Spectroscopy 1H MRS in Preclinical Research written by Ivina Mali and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) is widely used to non-invasively evaluate anatomical and physiological properties of tissues in both clinical and preclinical studies making it the gold standard in medical imaging. The protocols and workflows for MRI are well established; such is not the case for Magnetic Resonance Spectroscopy (MRS). In contrast to MRI or as a complement, MRS provides biochemical composition and quantitative information of the tissue being analyzed. Modern MRI scanners can be used for MRS without any hardware modifications. MR scanners used in the clinic are of low field strength (1.5 Tesla (T) or 3 T) and require contrast agents to improve the visibility of tissue structures. On the other hand, small animal imaging requires scanners of high field strength to acquire higher resolutions to visualize similar structures and produce clinically translatable results. In this study, we use an ultra-high-field scanner of 14.1 T and optimized pulse sequences to obtain MRI and image-guided-MRS data of high spatial and spectral resolution, respectively. This work focuses on small animal models of solid tumors and neurological disorders. We monitored the growth of pancreatic ductal adenocarcinomas (PDAC) on C57BL/6 mice using a RARE (Rapid Acquisition with Relaxation Enhancement) pulse sequence after tumor implantation. MRI-guided thermal treatments were applied to mouse models of PDACs and aldosterone-producing adenoma in vivo. To evaluate the tissues before and after treatment, T1 mapping techniques were used. Another objective of this study was to use single voxel 1H-MRS (Proton MRS) techniques to study metabolite levels in cell lines and tissues ex vivo. We used a PRESS (Point RESolved Spectroscopy) sequence to acquire spectral information from five different cell lines (four cancer and one non-cancer) and solid tumors excised from mouse models and human subjects. Short, intermediate, and long echo times (TEs) were explored where short TE was found effective in resolving major metabolites compared to conventional long TE scans. Spectra with high SNR (signal-to-noise ratio) were acquired from voxel sizes up to 2 x 2 x 2 mm3. The current work also uses the valproic acid (VPA) model of autism spectrum disorder (ASD) in rodents. We collected 3D MRI scans to measure gray matter volumes in cerebellar and frontal regions of VPA-treated and control rat brains ex vivo. High-resolution MRI data allowed accurate segmentation across different regions of the rat brains. Altogether, we demonstrate diverse applications of MRI and image-guided 1H-MRS in preclinical studies using an ultra-high-field scanner.

Download or read book Microstructural Parcellation of the Human Cerebral Cortex written by Stefan Geyer and published by Springer Science & Business Media. This book was released on 2013-07-04 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unraveling the functional properties of structural elements in the brain is one of the fundamental goals of neuroscientific research. In the cerebral cortex this is no mean feat, since cortical areas are defined microstructurally in post-mortem brains but functionally in living brains with electrophysiological or neuroimaging techniques – and cortical areas vary in their topographical properties across individual brains. Being able to map both microstructure and function in the same brains noninvasively in vivo would represent a huge leap forward. In recent years, high-field magnetic resonance imaging (MRI) technologies with spatial resolution below 0.5 mm have set the stage for this by detecting structural differences within the human cerebral cortex, beyond the Stria of Gennari. This provides the basis for an in vivo microanatomical brain map, with the enormous potential to make direct correlations between microstructure and function in living human brains. This book starts with Brodmann’s post-mortem map published in the early 20th century, moves on to the almost forgotten microstructural maps of von Economo and Koskinas and the Vogt-Vogt school, sheds some light on more recent approaches that aim at mapping cortical areas noninvasively in living human brains, and culminates with the concept of “in vivo Brodmann mapping” using high-field MRI, which was introduced in the early 21st century.

Download or read book The Cytoarchitectonics of the Human Cerebral Cortex written by Constantin Freiherr von Economo and published by . This book was released on 1929 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book 7T MRI An Issue of Magnetic Resonance Imaging Clinics of North America written by Meng Law and published by Elsevier Health Sciences. This book was released on 2020-11-30 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of MRI Clinics of North America focuses on 7T MRI and is edited by Dr. Meng Law. Articles will include: 3T vs 7T MRI: Is It Really Worth It?; High Resolution Structural MRI & Quantitative Susceptibility Mapping; High Resolution Neurovascular Imaging at 7T: Arterial Spin Labeling Perfusion, 4-dimensional MR Angiography and Black blood MRI; 7T and Beyond Functional MRI; Sodium and Other UHF MRI; MR-EYE: Ultra High Field MRI of the Human Eye and Orbit at 7T; 7T MRI of Perivascular Spaces; 7T MRI in “Non Lesional" Epilepsy/ Perivascular Spaces; 7T Multiple Sclerosis; 7T Brain Tumors and Radiation Therapy; 7T Musculoskeletal MRI; Body Applications for 7T; MRI Safety at 7T/Implants; 7T Simultaneous MRI PET with PET Insert; GluCest 7T MRI; and more!

Download or read book Measuring Oxidants and Oxidative Stress in Biological Systems written by Lawrence J. Berliner and published by Springer Nature. This book was released on 2020-08-08 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the methods of analysis and determination of oxidants and oxidative stress in biological systems. Reviews and protocols on select methods of analysis of ROS, RNS, oxygen, redox status, and oxidative stress in biological systems are described in detail. It is an essential resource for both novices and experts in the field of oxidant and oxidative stress biology.

Download or read book Handbook of MRI Pulse Sequences written by Matt A. Bernstein and published by Elsevier. This book was released on 2004-09-21 with total page 1041 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Imaging (MRI) is among the most important medical imaging techniques available today. There is an installed base of approximately 15,000 MRI scanners worldwide. Each of these scanners is capable of running many different "pulse sequences", which are governed by physics and engineering principles, and implemented by software programs that control the MRI hardware. To utilize an MRI scanner to the fullest extent, a conceptual understanding of its pulse sequences is crucial. Handbook of MRI Pulse Sequences offers a complete guide that can help the scientists, engineers, clinicians, and technologists in the field of MRI understand and better employ their scanner. Explains pulse sequences, their components, and the associated image reconstruction methods commonly used in MRI Provides self-contained sections for individual techniques Can be used as a quick reference guide or as a resource for deeper study Includes both non-mathematical and mathematical descriptions Contains numerous figures, tables, references, and worked example problems