Download or read book Improving the Light Quantification of Near Infrared NIR Diffused Light Optical Tomography with Ultrasound Localization written by Yasaman Ardeshirpour and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Solutions for Clinical Problems of Near Infrared NIR Light Imaging Reconstruction with Ultrasound Localization written by Chen Xu and published by . This book was released on 2008 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Optical Imaging of Breast Cancers written by Yan Xu and published by . This book was released on 2013 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Horizons in Time Domain Diffuse Optical Spectroscopy and Imaging written by Yoko Hoshi and published by MDPI. This book was released on 2020-06-23 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jöbsis was the first to describe the in vivo application of near-infrared spectroscopy (NIRS), also called diffuse optical spectroscopy (DOS). NIRS was originally designed for the clinical monitoring of tissue oxygenation, and today it has also become a useful tool for neuroimaging studies (functional near-infrared spectroscopy, fNIRS). However, difficulties in the selective and quantitative measurements of tissue hemoglobin (Hb), which have been central in the NIRS field for over 40 years, remain to be solved. To overcome these problems, time-domain (TD) and frequency-domain (FD) measurements have been tried. Presently, a wide range of NIRS instruments are available, including commonly available commercial instruments for continuous wave (CW) measurements, based on the modified Beer–Lambert law (steady-state domain measurements). Among these measurements, the TD measurement is the most promising approach, although compared with CW and FD measurements, TD measurements are less common, due to the need for large and expensive instruments with poor temporal resolution and limited dynamic range. However, thanks to technological developments, TD measurements are increasingly being used in research, and also in various clinical settings. This Special Issue highlights issues at the cutting edge of TD DOS and diffuse optical tomography (DOT). It covers all aspects related to TD measurements, including advances in hardware, methodology, the theory of light propagation, and clinical applications.
Download or read book Three Dimensional Near infrared Optical Imaging Using Ultrasound Guidance for Breast Cancer Detection and Diagnosis written by Minming Huang and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation focuses on the study of three-dimensional near-infrared (NIR) imaging reconstruction using ultrasound localization for breast cancer detection and diagnosis. With the 3D NIR forward model for reflection geometry built and investigated, successful reconstruction of both absorption and scattering coefficients has been obtained and evaluated using both a phantom study and initial clinic data. In this work, we first introduce a dual mesh optical reconstruction method with depth correction using a priori ultrasound information. It can significantly improve the reconstructed absorption distributions in deeper target layers. Clinical results have shown improved correlation between reconstructed total hemoglobin concentrations and the histological micorvessel density counts. Next, a combined Tikhonov regularization and dual mesh scheme based on finite element method (FEM) is proposed to solve the inter-parameter cross talk between the scattering coefficient and absorption coefficient. In this approach, the optimal regularization factor is given by the standard L-curve. Different regularization factors have been assigned to the target region and non-target region to incorporate the priori target information from the co-registered ultrasound images. Both phantom experiments and clinic examples have shown that this new approach has the ability to reconstruct the absorption and diffusion coefficients simultaneously, and the reconstructed target absorption and diffusion maps have no depth dependence effect. Finally, a simple two-layer model is generated and studied to solve a clinical issue related to the chest wall, which is a mixture of bones and muscles. For small breasts, the chest wall appears within 2–3 cm distance from the skin surface. As a result, the simple one layer model is not accurate. Furthermore, for some cases, there is also an obvious chest wall mismatch between the reference site and lesion site. To solve this clinical issue, a simplified two-layer model is generated and a fitting method is adopted to estimate the optical properties of both layers. Then a correction method is applied to correct for the chest wall mismatch between the lesion site and reference site. With this scheme, phantom targets located on top of the chest wall phantom layer can be reconstructed with good contrast and resolution.
Download or read book Developments in Near Infrared Spectroscopy written by Konstantinos Kyprianidis and published by BoD – Books on Demand. This book was released on 2017-03-15 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few decades, exciting developments have taken place in the field of near-infrared spectroscopy (NIRS). This has been enabled by the advent of robust Fourier transform interferometers and diode array solutions, coupled with complex chemometric methods that can easily be executed using modern microprocessors. The present edited volume intends to cover recent developments in NIRS and provide a broad perspective of some of the challenges that characterize the field. The volume comprises six chapters overall and covers several sectors. The target audience for this book includes engineers, practitioners, and researchers involved in NIRS system design and utilization in different applications. We believe that they will greatly benefit from the timely and accurate information provided in this work.
Download or read book Three dimensional Ultrasound Imaging and Its Applications in Combined Near infrared Optical Imaging and Co registered Photoacoustic Imaging written by Puyun Guo and published by . This book was released on 2007 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation focuses on three-dimensional (3-D) ultrasound and its applications as an adjunct modality for biomedical optical imaging.
Download or read book Advances in Near Infrared Spectroscopy and Related Computational Methods written by Christian Huck and published by MDPI. This book was released on 2020-01-03 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last few decades, near-infrared (NIR) spectroscopy has distinguished itself as one of the most rapidly advancing spectroscopic techniques. Mainly known as an analytical tool useful for sample characterization and content quantification, NIR spectroscopy is essential in various other fields, e.g. NIR imaging techniques in biophotonics, medical applications or used for characterization of food products. Its contribution in basic science and physical chemistry should be noted as well, e.g. in exploration of the nature of molecular vibrations or intermolecular interactions. One of the current development trends involves the miniaturization and simplification of instrumentation, creating prospects for the spread of NIR spectrometers at a consumer level in the form of smartphone attachments—a breakthrough not yet accomplished by any other analytical technique. A growing diversity in the related methods and applications has led to a dispersion of these contributions among disparate scientific communities. The aim of this Special Issue was to bring together the communities that may perceive NIR spectroscopy from different perspectives. It resulted in 30 contributions presenting the latest advances in the methodologies essential in near-infrared spectroscopy in a variety of applications.
Download or read book Near Infrared Spectroscopy written by Yukihiro Ozaki and published by Springer Nature. This book was released on 2020-11-13 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides knowledge of the basic theory, spectral analysis methods, chemometrics, instrumentation, and applications of near-infrared (NIR) spectroscopy—not as a handbook but rather as a sourcebook of NIR spectroscopy. Thus, some emphasis is placed on the description of basic knowledge that is important in learning and using NIR spectroscopy. The book also deals with applications for a variety of research fields that are very useful for a wide range of readers from graduate students to scientists and engineers in both academia and industry. For readers who are novices in NIR spectroscopy, this book provides a good introduction, and for those who already are familiar with the field it affords an excellent means of strengthening their knowledge about NIR spectroscopy and keeping abreast of recent developments.
Download or read book Proceedings of Optical Tomography and Spectroscopy of Tissue III written by Britton Chance and published by SPIE-International Society for Optical Engineering. This book was released on 1999 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book 3D Near Infrared Diffuse Wave Imaging With Ultrasound Localization written by and published by . This book was released on 2005 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: This proposal is focused on the three-dimensional NIR imaging reconstruction using ultrasound localization for cancer detection and diagnosis. During the reported period, we have achieved simultaneous reconstruction of optical absorption and scattering coefficients of heterogeneities using a dual-mesh scheme based on finite element method, and introduced a new simple two-layer model to correct diffusive wave distortion caused by underlying chest wall of patients.
Download or read book Near Infrared Technology written by Phil Williams and published by AFRICAN SUN MeDIA. This book was released on 2019-09-01 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imagine an analytical technique that uses no chemicals, gives accurate and precise results in minutes or even continuously, and is simple to install and safe to use. Near-infrared spectroscopy (NIRS) supplies this dream. This book covers all of the essential features for successful NIRS application in a practical and easily understandable format. The driving force behind compiling this book is to provide knowledge on all aspects of NIRS to potential users, and to users who would like to delve a little deeper into the technology. We have assembled the book, mainly to help in the application of near-infrared (NIR) instruments and technology in industry.
Download or read book Optical Tomography and Spectroscopy of Tissue VII written by Britton Chance and published by SPIE-International Society for Optical Engineering. This book was released on 2007 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theory/Algorithm/Modeling; Instrumentation and Technology I; Fluorescence Imaging/Spectroscopy (algorithm/model/tomography); Fluorescence Imaging/Image Reconstruction (Experimental); Instrumentation and Technology II; Fluorescence Imaging Technology I; Fluorescence Imaging Technology II; Fluorescence Imaging Technology III; Network for Translational Research in Optical Imaging: Breast Cancer Diffuse Optical Imaging; Breast II - Instrumentation & New Analysis Method; Breast III - Clinical Study; Pre-Clinical/Animal; Instrumentation and Technology III; Clinical/Human Subject Studies.
Download or read book Near infrared Speckle Contrast Diffuse Correlation Tomography for Noncontact Imaging of Tissue Blood Flow Distribution written by Daniel Irwin and published by CRC Press. This book was released on 2022-11-07 with total page 61 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging of tissue blood flow (BF) distributions provides vital information for the diagnosis and therapeutic monitoring of various vascular diseases. The innovative near-infrared speckle contrast diffuse correlation tomography (scDCT) technique produces full 3D BF distributions. Many advanced features are provided over competing technologies including high sampling density, fast data acquisition, noninvasiveness, noncontact, affordability, portability, and translatability across varied subject sizes. The basic principle, instrumentation, and data analysis algorithms are presented in detail. The extensive applications are summarized such as imaging of cerebral BF (CBF) in mice, rat, and piglet animals with skull penetration into deep brain. Clinical human testing results are described by recovery of BF distributions on preterm infants (CBF) through incubator wall, and on sensitive burn tissues and mastectomy skin flaps without direct device-tissue interactions. Supporting activities outlined include integrated capability for acquiring surface curvature information, rapid 2D blood flow mapping, and optimizations via tissue-like phantoms and computer simulations. These applications and activities both highlight and guide the reader as to the expected abilities and limitations of scDCT for adapting into their own preclinical/clinical research, use in constrained environments (i.e., neonatal intensive care unit bedside), and use on vulnerable subjects and measurement sites.
Download or read book Ultrasound encoded Optical Tomography and Time reversed Ultrasonically Encoded Optical Focusing written by Xiao Xu and published by . This book was released on 2011 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrasound modulated optical tomography is a developing hybrid imaging modality that combines high optical contrast and good ultrasonic resolution to image soft biological tissue. We developed a photorefractive crystal-based, time-resolved detection scheme with the use of a millisecond long ultrasound burst to image both the optical and mechanical properties of biological tissues, with improved detection efficiency of ultrasound-tagged photons. We also applied spectral-hole burning (SHB) aided detection in ultrasound-modulated optical tomography (UOT) to image optical heterogeneities in thick tissue-mimicking phantom samples and chicken breast tissue. The efficiency of SHB was improved by using a Tm3+: YAG crystal of higher doping concentration (2.0-atomic%) and a double-pass pumping configuration. With the improved SHB-UOT system, we imaged absorbing, scattering, and phase contrast objects that were embedded in the middle plane of a 30-mm thick phantom sample. The imaging resolution was 0.5 mm in the lateral direction, as defined by the focal width of the ultrasonic transducer, and 1.5 mm in the axial direction, as determined by the ultrasonic burst length. We also imaged two absorbing objects embedded in the middle plane of a 32-mm thick chicken breast sample. The results suggest that the improved SHB-UOT system is one step closer to a practical optical imaging application in biological and clinical studies. Light focusing plays a central role in biomedical imaging, manipulation, and therapy. In optical scattering media such as biological tissue, light propagation is randomized by multiple scattering. Beyond one transport mean free path, where photon propagation is in the diffusive regime, direct light focusing becomes infeasible. Although various methods have been developed to overcome this optical diffusion limit, all are limited by the lack of a practical internal "guide star." Here we proposed and experimentally validated a novel concept, called Time-Reversed Ultrasonically Encoded (TRUE) optical focusing, to deliver light dynamically into any predefined location inside a scattering medium. First, diffused coherent light is encoded by an ultrasonic wave focused to a predefined location; then, the encoded component of the diffused light is time-reversed and consequently converges back to the ultrasonic focus. The ultrasonic encoding noninvasively provides a virtual internal "guide star" for the time reversal. The TRUE optical focus--dynamically defined by the ultrasonic focus--is unaffected by multiple scattering of light, which is especially desirable in biological tissue where ultrasonic scattering is ~1000 times weaker than optical scattering. Various fields, such as biomedical, colloidal, atmospheric, and ocean optics, can benefit from TRUE optical focusing. Further, the concept can be generalized for non-optical waves.
Download or read book Photon Migration and Diffuse light Imaging written by and published by . This book was released on 2005 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Horizons in Time Domain Diffuse Optical Spectroscopy and Imaging written by Yoko Hoshi and published by . This book was released on 2020 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jöbsis was the first to describe the in vivo application of near-infrared spectroscopy (NIRS), also called diffuse optical spectroscopy (DOS). NIRS was originally designed for the clinical monitoring of tissue oxygenation, and today it has also become a useful tool for neuroimaging studies (functional near-infrared spectroscopy, fNIRS). However, difficulties in the selective and quantitative measurements of tissue hemoglobin (Hb), which have been central in the NIRS field for over 40 years, remain to be solved. To overcome these problems, time-domain (TD) and frequency-domain (FD) measurements have been tried. Presently, a wide range of NIRS instruments are available, including commonly available commercial instruments for continuous wave (CW) measurements, based on the modified Beer-Lambert law (steady-state domain measurements). Among these measurements, the TD measurement is the most promising approach, although compared with CW and FD measurements, TD measurements are less common, due to the need for large and expensive instruments with poor temporal resolution and limited dynamic range. However, thanks to technological developments, TD measurements are increasingly being used in research, and also in various clinical settings. This Special Issue highlights issues at the cutting edge of TD DOS and diffuse optical tomography (DOT). It covers all aspects related to TD measurements, including advances in hardware, methodology, the theory of light propagation, and clinical applications.
